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ANTIBIOTIC RESISTANCE IS HAPPENING NOW.

The race is on.
#PowerOfAntibiotics





ANTIBIOTICS ARE THE FOUNDATION OF MODERN MEDICINE. WE NEED TO ENSURE IT STAYS
THAT WAY.

Across the world, drug-resistant infections are on the rise. Meanwhile,
investments in the antibiotics needed to control them remain dangerously low,
too low to change that.



Business as usual is not enough. In the run-up to the United Nations General
Assembly High-Level Meeting on Antimicrobial Resistance (AMR), GARDP and other
organizations are coming together to raise awareness on the need to invest in
antibiotic research and development.

The race is on.

Support the campaign
Learn about GARDP



NO ONE IS SAFE

Meet the people affected by antibiotic resistance.

MELISSA'S STORY

Melissa Nelson is a disease intervention specialist with the Jefferson County
Department of Health, in Birmingham, Albama, USA. When someone is diagnosed with
a sexually transmitted infection, it is Melissa's job to investigate from where
it has come and to stop it from spreading further.

"People affectionately call us 'sex detectives'," she says.

When engaging with young people who feel invincible, Melissa asks them, "What
would you do if we started to see a drug-resistant strain of gonorrhoea here in
Birmingham, Alabama? Because it exists."

Learn more about GARDP's work

ASHISH'S STORY

Dr Ashish Abraham runs medical camps in villages in Madhepura, a rural district
in the state of Bihar in northern India, to offer care to the Musahars, part of
India's "Scheduled Castes" (i.e. the lowest caste, formerly "the untouchables").

It was during one of these health camps that Ashish found a child with Mycetoma,
also known as Madura foot, caused by actinomyces bacteria. It would take several
months of antibiotic treatment to fight off the infection.

"We've started building rapport and earning trust," says Dr Abraham. "That is
the first step in providing the Musahars with accessible healthcare, including
effective treatment of bacterial infections."

Learn more about GARDP's work

HILARY'S STORY

As an oncologist in the UK, Hilary had treated thousands of patients for cancer
over the years, but nothing prepared her for her own cancer diagnosis. "Until
you're there, you can't stand in those shoes," she says.

Doctors put Hilary on an aggressive treatment regimen that included chemotherapy
and a medication meant to boost the production of white blood cells to
strengthen the immune system.

"I was very aware of the risk of sepsis," says Hilary, who completed her
treatment successfully 17 years ago. "We need to be having conversations with
people across society about the dangers of antimicrobial resistance for cancer
patients and others."



Learn more about GARDP's work

JUDITH'S STORY

As the head nurse of a neonatal intensive care unit, Judith is always on the
look-out for signs of problems, including neonatal sepsis, the body's
life-threatening reaction to severe infection. "One moment they seem to be
improving and getting better, and in a matter of hours things change," says
Judith.

In the case of sepsis, doctors must administer antibiotics quickly.
Unfortunately, she and her colleagues have noticed that the standard treatments
for neonatal sepsis are increasingly ineffective. Finding good treatment options
is becoming harder and harder.

Learn more about GARDP's work

HELMI'S STORY

Dr Helmi bin Sulaiman had carefully tended to his patient at the University of
Malaya, Malaysia. He treated the man for life-threatening bacterial infections
in his liver and bloodstream, and then an infection in his lungs. But now the
infection had returned.

Dr Helmi was granted special permission known as "compassionate use" to treat
the patient with a recently approved antibiotic that is not currently available
in Malaysia. After a long recovery, the patient walked out of the hospital
infection-free.

"This compassionate use programme has helped us a lot," said Dr Helmi. "But it
doesn't solve the problem: I do not have access to the right medications."

Learn more about GARDP's work

JEMIN'S STORY

Just weeks before, the patient was a strong and healthy 25-year-old who farmed
and drove a tractor in this region that is known throughout the world for its
famous Assam black tea. Now he was unable to walk.

Dr Jemin Webster started running tests and eventually diagnosed the patient with
melioidosis, a bacterial infection that is more common in the region than
elsewhere.

Jemin administered antibiotics following guidelines, and slowly his young
patient began to recover. However Jemin cannot take available antibiotics for
granted: "One of the main challenges in treating bacterial infection here is the
lack of availability of antibiotics, particularly the narrow-spectrum
antibiotics," says Jemin.

Learn more about GARDP's work

SERGEI'S STORY

Together with countries around the world, Ukraine was badly hit by COVID-19.
"Many patients were afraid of getting sick and dying, and insisted on getting
antibiotics," says Sergei Petrik, a doctor in Mariupol.

Many doctors were scared too. Despite WHO and national guidance not to prescribe
antibiotics for COVID-19, Sergei says some pushed ahead, risking antibiotic
resistance. Then, as Ukraine was emerging from the pandemic, it was caught in
the grip of war.

With injuries mounting and often unsanitary conditions, doctors turned to
antibiotics to treat infections. But some of them no longer worked.

"Infection and antibiotic resistance came alongside the war. It's been a hard
lesson to use antibiotics wisely," says Sergei.

GREGORY'S STORY

Pneumonia. Together with other lower respiratory infections, it is the fourth
leading cause of death worldwide.

Gregory Carson, from Perth, knows this threat all too well. In the first half of
2023, he suffered from a bout of pneumonia that made him fear for his life.

"The antibiotic that saved me is 60 years old and cost less than US$5."

His experience motivated him to speak out about the need to develop the next
generation of life-saving antibiotics.

"I'm aware of the issue of drug resistance. I wish all inexpensive antibiotics
in developed countries had a levy to fund antibiotic resistance research."

ORUM'S STORY

When Prudence felt the first contraction, she knew something was wrong. "I was
scared. I knew it was not time, but the baby was coming," she recalls. Rushed to
the Kawempe Hospital, Prudence gave birth to her son Orum at just 24 weeks.

When doctors discovered Orum had pneumonia, they gave him a first-line
antibiotic treatment intravenously. However, Orum did not immediately recover.

It took several rounds of treatment before he was discharged to continue
recovery at home. Now Orum is healthy and ready to start school.

Learn more about GARDP's work

ASTRID'S STORY

Astrid was in labour at Geneva University Hospitals when she started to shiver
and vomit and her temperature soared to 39.9°C. Doctors realized that she had a
life-threatening bloodstream infection, and there wasn't a moment to spare.

"I had worried about my baby, but until then, I had never worried about myself,"
says Astrid.

Soon, Astrid was being treated with antibiotics intravenously, and she gave
birth to a healthy baby girl. "Without antibiotics, I would not be here," she
says.

Learn more about GARDP's work

CHELSEA'S STORY

When a drug-resistant infection swept through her COVID-19 ward, Chelsea found
herself on the frontline of the COVID-19 pandemic and confronting an outbreak of
drug-resistant Klebsiella pneumonia.

"Not only were patients battling with the virus, they then had to face a
secondary infection on top of it, which could often not be treated because of
antibiotic resistance," says Chelsea.

"It took COVID-19 to make me realise how crucial it is to have effective
antibiotics."

Learn more about GARDP's work

HASSAN'S STORY

In southern Syria, expert nurse, Hassan Khatar, is working together with his
colleagues to use antibiotics with care. When used wisely, antibiotics have made
a huge difference to his patients.

“We must work together with international organisations to increase awareness of
how to safely and correctly use antibiotics to prevent antibiotic resistance,”
says Hassan, who has worked as a nurse in Syria for the past 30 years.

Hassan suggests that nurses and doctors should attend seminars and learn about
new developments in the use of antibiotic treatments and care of patients.
“Improving our knowledge and experience will lead towards a better and healthier
life for patients.”

HONAR'S STORY

For over 30 years, Dr Honar Cherif has been treating cancer patients. For these
patients, serious bacterial infections are a significant threat, with some
needing several rounds of antibiotic treatments.

But in recent years, many countries, including those in Europe, are reporting
increased antibiotic resistance.

"Infections caused by multi-resistant bacteria such as methicillin-resistant
Staphylococcus aureus (MRSA) and extended-spectrum beta-lactamase producing
(ESBL) bacteria do not respond to the broad-spectrum antibiotics we use to
manage infections in these immunocompromised patients," says Honar.

"If we get to a point where we cannot prevent and treat these serious
infections, we will have a very difficult time treating cancer with
chemotherapy. This, of course, has catastrophic consequences."

Learn more about GARDP's work

In collaboration with

GUSTAVO'S STORY

How might you teach young schoolchildren about antibiotic resistance?

As a teacher in Cuenca, Ecuador, Gustavo Cedillo has drawn on ReAct’s Alforja
Educativa—or "educational saddlebag" in Spanish.

"It allows children to discover the natural world of bacteria and the balance
needed to care for human health and nature," says Gustavo.

In one of its games, children as young as 5 or 6 years old stand inside a circle
and attempt to block children outside from getting in. The game simulates
antibiotics that are unable to get into bacteria cells or are ejected from those
cells (both of which are resistance mechanisms).

"During the first years of schooling the students are very perceptive and open
to play, which makes it easier to capture their interest in discovery and
exploration of nature," says Gustavo.

Learn more about GARDP's work

In collaboration with

DANIEL'S STORY

Kenyan advocate, Daniel Waruingi, is shining a spotlight on one of the most
pressing issues of our time….antimicrobial resistance (AMR).

Together with a fellow student, he founded ‘Students Against Superbugs Africa’
to counter the threat of AMR.

As ‘AMR Champions’ young professionals and students in Kenya and other African
countries set up AMR awareness initiatives in universities, colleges, schools,
clinics and communities. Daniel and his team also offer support and training.
Through their work, they’ve generated a wave of positive change.

"All of us are playing our part to improve our health and curtail the spread of
antibiotic-resistant infections. Our end goal is to have a global youth
movement, originated in Africa, to mitigate the threat of AMR," says Daniel.

Learn more about GARDP's work

In collaboration with

JEREMY'S STORY

Dr Jeremy Nel is the Head of Infectious Diseases at the Helen Joseph Hospital in
Johannesburg, South Africa-one of the biggest hospitals in Johannesburg and one
of the biggest HIV clinics in the world.

Over the past couple decades, he's seen huge progress against HIV/AIDS, driven
in large part by free access to antiretroviral medications.

But future progress is in jeopardy.

"Antimicrobial resistance is one of the absolute top things that could set back
progress in HIV patients. I mean we have the HIV drugs now-that's not the
limiting factor. One of the things that might make things go backwards is AMR,"
says Jeremy.

Learn more about GARDP's work

MOMIPAL'S STORY

Drug-resistant bacteria isn't just affecting Momipal’s health, it is also
threatening her family's livelihood. Having been repeatedly hospitalized by a
series of infections, this has led to out-of-pocket expenses that are placing
additional economic pressure on her and her family.

For a growing number of people this is the grim reality of the antimicrobial
resistance (AMR) crisis. Not only is it already one of the world’s biggest
killers, but over the coming decade it also threatens to push 24 million more
people like Momipal into medical impoverishment.

Learn more about GARDP's work

BENZ'S STORY

Benz* lives and works in Thailand. Recently he met a man on an online dating app
and they arranged to get together. After a great night out, they ended up having
unprotected sex. A few days later, Benz realized something wasn’t right when he
felt a sharp pain while urinating.

Feeling anxious, he was tempted to search for medication online, but then made a
wise decision to see a doctor. Benz was tested for a sexually transmitted
infection, diagnosed with gonorrhoea and prescribed antibiotic treatment.

"Looking back, I am proud of my decision to seek treatment early from a doctor.
Thanks to antibiotics, I am cured from the infection."

*not his real name

Learn more about GARDP's work

LILLIAN'S STORY

As an oncologist at The Hospital for Sick Children (SickKids) in Toronto,
Canada, Professor Lillian Sung specializes in treating children with blood
cancer like leukaemia.

Although in recent decades, survival rates for this group of patients have
increased, infections continue to pose a serious threat.

"Some bacterial infections are easily treated, and after a course of
antibiotics, the infection is gone," says Lillian. "But they can also be
difficult to treat and lead to significant morbidity. And in the very worst-case
scenario, the child can die."

Learn more about GARDP's work


Prof Lillian Sung is part of the Union for International Cancer Control
taskforce on antimicrobial resistance (AMR) and cancer care.


Load more



IT’S HARD TO IMAGINE LIFE WITHOUT ANTIBIOTICS.

But, with drug resistance already one of the world’s biggest killers and rising,
that’s exactly where we’re heading.

0 million
deaths associated with drug-resistant infections every year
1 in 0
of those deaths occur in children under 5
0 years
increase in life expectancy due to antibiotics


A GLOBAL CRISIS NEEDS A GLOBAL SOLUTION.

Drug resistance doesn’t have to mean ‘Game Over’. All over the world,
researchers, scientists, civil society and private organizations are taking
steps to ensure that people get the protection they need from drug-resistant
infections, today and for generations to come.



Together we can do more.

We all have a part to play. As part of this global effort, GARDP is working to
support the development of essential new antibiotic treatments, and make sure
that they are available to everyone who needs them.

Join us
Learn about GARDP
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ARE YOU READY TO TAKE ACTION?


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OUR CAMPAIGN

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new progress in antibiotic research, development and access.

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OUR COMMUNITY

Our REVIVE community is committed to sharing knowledge, skills and developments
in R&D. Membership is open to students, academics and researchers alike.

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ORGANIZATIONS ACROSS THE WORLD ARE JOINING THE RACE TO REVIVE THE POWER OF
ANTIBIOTICS.

Will yours be next?





ABOUT GARDP


THE GLOBAL ANTIBIOTIC RESEARCH & DEVELOPMENT PARTNERSHIP

To address the challenge of antibiotic resistance, we need to recognize the
market and public health failures that have contributed to it.

Established in 2016, GARDP is the only organization in the world working to
address both issues simultaneously. Driven by public health needs rather than
profit, we work in partnership to develop new antibiotic treatments and expand
access to them.

Find out more



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