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Skip to content SimpleMicrofluidics * DIY Microfluidics Prototyping * Duplicate an Existing Circuit * PDMS Fabrication Techniques * Overview * What is PDMS? * 3D Printed Mold * Metal Micromilling * Puffy Paint Mold * Duplicate an Existing Circuit * ABS Sheet Mold * ESCARGOT * PDMS Surface Modification * Corona Discharge * SolGel (TEOS) * SolGel (Glass) * SolGel (Borosilicate Glass) * O2 Plasma (Plasma Cleaner) * O2 Plasma (Microwave) * Surfactant In-molding * PEGMEM Modification * PVA Deposition * PVP Coating * Silinization * Chemical Micropatterning * Polymer Brushing (Grafting-to) * Polymer Brushing (Grafting-from) * Silicon-Oxide Layer * Paper Fabrication Techniques * Overview * Laser Cutting * Wax Printing * Wax Stamping * Wax Tracing * Paper and Tape * Stamp Printing Ink * Stamp Printing PDMS * Flash Foam Stamping * Screen Printing * Printed Polyester Film * Embossing * Ink Plotting * Plasma Treatment * Microfluidics News SIMPLE MICROFLUIDICS EVERYTHING YOU WANT TO KNOW ABOUT MICROFLUIDICS MANUFACTURING Become the microfluidics fabrication expert at your lab PDMS MICROFLUIDICS MOLDING -------------------------------------------------------------------------------- * Overview * What is PDMS? * 3D Printed Mold * Metal Micromilling * Puffy Paint Mold * Duplicate a PDMS circuit * ABS sheet mold * ESCARGOT DUPLICATE A CHIP -------------------------------------------------------------------------------- * How to duplicate a microfluidic chip PAPER MICROFLUIDIC FABRICATION -------------------------------------------------------------------------------- * Overview * Laser Cutting * Wax Printing * Wax Stamping * Wax Tracing * Movable Type Wax Printing * Paper and Tape * Stamp Printing Ink * Stamp Printing PDMS * Flash Foam Stamping * Screen Printing * Laser Printed Polyester Film * Embossing * Ink Plotting * Plasma Treatment * Silicon-Oxide Layer (UV/Ozone Treatment) PDMS SURFACE MODIFICATION -------------------------------------------------------------------------------- * SolGel (TEOS) * SolGel (Glass) * SolGel (Borosilicate glass) * O2 Plasma (Plasma Cleaner) * O2 Plasma (Microwave) * Surfactant in-molding * PEGMEM Modification * PVA Deposition * PVP Coating * Silinization * Chemical Micropatterning * Polymer Brushing (grafting-to) * Polymer Brushing (grafting-from) * Charged Polymers BECOME THE FABRICATION EXPERT AT YOUR LAB Get concise summaries of new fabrications techniques and research papers right in your inbox WHY MICROFLUIDICS? > We all know about the miracle of miniaturization. Back in the day, computers > used to fill this entire room, and people actually used to work inside the > computers. [..] The good news is that the same technology that allowed > miniaturization of electronics is now allowing us to miniaturize biological > laboratories. So, right now, we can actually miniaturize biological and > chemistry laboratories onto microfluidic chips [..] so you have integrated > valves, pumps, mixers and injectors — so you can fit entire diagnostic > experiments onto a microfluidic system. > > Fredrick Balagadde, UMass Lowell > By combining tissue engineering techniques with microfluidics, the field is > actually evolving towards just that, a model of the entire ecosystem of the > body, complete with multiple organ systems to be able to test how a drug you > might take for your blood pressure might affect your liver or an > antidepressant might affect your heart. These systems are really hard to > build, but we’re just starting to be able to get there, and so, watch out. > > Nina Tandon, CEO @ EpiBone > This could really revolutionize and be a game changer for not only the > pharmaceutical industry, but a whole host of different industries, including > the cosmetics industry. We can [..] test whether the ingredients in those > products that you’re using are actually safe to put on your skin without the > need for animal testing. We could test the safety of chemicals that we are > exposed to on a daily basis in our environment, such as chemicals in regular > household cleaners. We could also use the organs on chips for applications in > bioterrorism or radiation exposure. We could use them to learn more about > diseases such as ebola or other deadly diseases such as SARS. > > Geraldine Hamilton, Wyss Institute Harvard ADDITIONAL RESOURCES 1. Greg Nordin: New Tools, New Possibilities – 3D Printing for Lab-on-a-Chip 2. 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