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Eat|How Does Alcohol Affect the Gut Microbiome?

https://www.nytimes.com/2024/01/30/well/eat/alcohol-gut-health-microbiome.html
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HOW DOES ALCOHOL AFFECT THE GUT MICROBIOME?

Scientists are just beginning to explore the relationship between drinking and
the good and bad bacteria in your gut.

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Credit...Mojo Wang


By Alice Callahan

Published Jan. 30, 2024Updated Feb. 1, 2024
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guidance to live your healthiest life. Get it with a Times subscription.

A frothy beer or a glass of wine can enhance a meal and settle the mind. But
what does alcohol do to the trillions of microbes living in your gut?

As with much of microbiome science, “there is a lot that we don’t know,” said
Dr. Lorenzo Leggio, a physician-scientist who studies alcohol use and addiction
at the National Institutes of Health.

That said, it’s clear that happy microbes are essential for proper digestion,
immune function and intestinal health. And as scientists begin to explore how
drinking may influence your gut, they’re learning that overdoing it could have
some unhappy consequences.


HOW DOES HEAVY DRINKING AFFECT YOUR MICROBIOME?

Most of the available research on alcohol and the microbiome has focused on
people who drink regularly and heavily, said Dr. Cynthia Hsu, a
gastroenterologist at the University of California, San Diego.



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A handful of studies, for instance, have found that people with alcohol use
disorder (the inability to control or stop problematic drinking) often have an
imbalance of “good” and “bad” bacteria in their guts. This is called dysbiosis,
and it is generally associated with greater inflammation and disease compared
with having a healthier microbiome, Dr. Hsu said.

Heavy drinkers with dysbiosis can also have “leakier,” or more permeable,
intestinal linings, Dr. Leggio said. A healthy gut lining acts as a barrier
between the interior of the intestine — full of microbes, food and potentially
harmful toxins — and the rest of the body, he said.

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Alice Callahan is a Times reporter covering nutrition and health. She has a
Ph.D. in nutrition from the University of California, Davis. More about Alice
Callahan

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