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   * About HipSci
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 * About Us About Us
   * About Us
   * Investigators
   * Funders and partners
   * News
 * Cell lines Cell lines
   * Cell lines
   * Cohorts
   * Using HipSci lines for your research > Using HipSci lines for your research
     * Purchase lines
     * Navigating our cell line browser
     * Culturing feeder-free lines
     * Culturing feeder-dependent lines
     * Trouble shooting iPSC culture
   * FAQs on cell lines
 * Data Data
   * Data
   * Assays
   * Using hipsci data for your research Using hipsci data for your research
     * The data-an overview
     * How to apply for managed access data
     * Finding and downloading data
   * FAQs on data


HUMAN INDUCED PLURIPOTENT STEM CELL INITIATIVE

HipSci brings together diverse constituents in genomics, proteomics, cell
biology and clinical genetics to create a global iPS cell resource

Cell lines and data browser



ABOUT US

Meet the team and learn more about our partners and us.


CELL LINES

Hundreds of iPSC lines derived from healthy and rare disease donors.


DATA

Extensive characterisation data available for all iPSC lines


ABOUT HIPSCI

The Human Induced Pluripotent Stem Cells Initiative (HipSci) is generating a
large, high-quality reference panel of human iPSC lines for the research
community.

HipSci stands apart from other iPSC projects in a number of respects:

 * Magnitude – HipSci is systematically generating iPSCs from hundreds of donors
   using a standardised experimental pipeline.
 * Cell line availability – HipSci’s cell lines are produced as a global iPSC
   resource. The cell lines are readily available from two cell banks (ECACC and
   EBiSC), for use by the wider research community.
 * Cohorts – HipSci’s reference panel comprises hundreds of cell lines from
   phenotypically healthy donors, plus several cohorts of donors with inherited
   genetic diseases.
 * The data – – Each line generated is extensively characterised. Assays include
   genotyping by array, expression array, methylation array, RNA-seq, Exome-seq,
   proteomics mass spectrometry, and high content cellular phenotyping.




NEWS


PUBLICATION

 * Common genetic variation drives molecular heterogeneity in human iPSCs
 * Genetic effects on chromatin accessibility foreshadow gene expression changes
   in macrophage immune response
 * Molecular and functional variation in iPSC-derived sensory neurons


ANNOUNCEMENTS

 * HipSci symposium in London, 22nd March 2018
 * HipSci symposium in London, 5th July 2017
 * Watch HipSci's online training webinar




Archived News


HIPSCI WORKFLOW


 * PATIENT RECRUITMENT
   
    * HEALTHY VOLUNTEERS
    * RARE DISEASE VOLUNTEERS


 * SOMATIC CELL ISOLATION
   
    * SKIN BIOPSY
    * PERIPHERAL BLOOD MONONUCLEAR CELLS


 * IPSC REPROGRAMMING
   
   CYTOTUNE SENDAI REPROGRAMMING
   
    * KLF4
    * C-MYC
    * SOX2
    * OCT3/4


 * QUALITY CONTROL
   
   
   


 * CELL BANKING
   
   
   
   
   


 * GENETIC AND GENOMICS ASSAYS
   
    * RNA SEQ
    * DNA METHYLATION
    * WHOLE GENOME SEQ
    * EXOME SEQ


 * CELULAR PHENOTYPING ASSAYS


 * PROTEOMICS ASSAYS

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