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SaferWorldbyDesign

SaferWorldbyDesign is a solution-oriented, safety assessment platform supporting
the design and testing of
intelligent, safer products using new approach methods in toxicology and next
generation risk assessment.

 Shop  Solutions

Explore

How we work

We offer you personalized support throughout the entire supply chain to ensure
your product's and brand's integrity.

GET IN TOUCH

Getting in touch with us is easy. We offer Webinar sessions and 1-to-1 Demo
meetings where you and your team will learn more about how our services can
support you. Register online now!

Contact us

GET A CONSULTATION

A consultation session is a next step. Here we learn more about your case and
define together the strategy to success. We know how overwhelming the process
can be, so we are there for you - from consultation to testing, data
implementation, final reporting, to brand building.

WE ASSESS

We work hard to identify any toxicological endpoints that can be relevant to
include in the testing pipeline. We'll provide you with the analysis data and
run more tests as necessary.

GET A SOLUTION

When you've reached this stage, you know what effects the ingredients in your
product can have on human and environmental health. We can identify and suggest
safer and greener alternatives when needed.

PRODUCT READY!

Success! Your product is ready to be safely marketed and distributed. You can
stand out through your brand and show how much you care about your customers'
skin and the environment.

How we work

STEP 1: GET IN TOUCH

Getting in touch with us is easy. We offer Webinar sessions and 1-to-1 Demo
meetings where you and your team will learn more about how our services can
support you. Register online now!

Book a 1-1 Demo now

STEP 2: GET A CONSULTATION

A consultation session is a next step. Here we learn more about your case and
define together the strategy to success. We know how overwhelming the process
can be, so we are there for you - from consultation to testing, data
implementation, final reporting, to brand building.

STEP 3: WE ASSESS

We work hard to identify any toxicological endpoints that can be relevant to
include in the testing pipeline. We'll provide you with the analysis data and
run more tests as necessary.

STEP 4: GET A SOLUTION

When you've reached this stage, you know what effects the ingredients in your
product can have on human and environmental health. We can identify and suggest
safer and greener alternatives when needed.

YOUR PRODUCT IS READY!

Success! Your product is ready to be safely marketed and distributed. You can
stand out through your brand and show how much you care about your customers'
skin and the environment.



What would you like to do...

Explore SaferWorld

SaferWorldbyDesign is a solution-oriented, safety assessment platform supporting
the design and testing of intelligent, safer products using new approach methods
in toxicology and next generation risk assessment.

More

Become a partner

Our partners bring expertise in the best emerging research methods in
toxicology, biology, chemistry, risk assessment and computer science to provide
a one-stop shop for designing safer products.

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Shop Products

Choose from our wide selection of products and services, ready for you to use
as-is or customized. Contact our support Knowledge Desk for advice and
consultation on your problem.

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Request Consultation or Quotation

Contact us to discuss which solutions are most relevant for your current
problems and work situation or to ask us for advice on solutions you need.

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Book a demo call

SaferWorldbyDesign Solutions

Under the SaferWorldbyDesign platform, we provide solutions, products and
services to:


COMBINED EXPERTISE FOR INTEGRATED SOLUTIONS

SaferWorldbyDesign integrates in silico and in vitro methods to develop standard
and premium Integrated Approaches to Testing and Assessment (IATAs), including
methods that support ingredient screening, product design and the preparation of
regulatory dossiers.


Together, the SaferWorldbyDesign partners supply commercial solutions, products
and services to:


 * Help industry incorporate the latest methods from complex science into
   business processes;
 * Prepare evidence and regulatory dossiers;
 * Promote the design and management of safer products throughout the life
   cycle;
 * Translate new assessment methods to best practices;
 * Support alternative methods and implementation of 3Rs principles on the
   Replacement, Reduction and Refinement of animal testing.


Historically, products have been tested using animal testing. We adhere and
pursue the 3Rs principles of the refinement, reduction and replacement of such
animal testing through the integrated use of modern interdisciplinary science.
Such an integration supports the use of all evidence available from chemistry,
biology, toxicology, medicine and environmental science, combined with best data
and computational science practices and methods.

Learn More


SAFERWORLDBYDESIGN SOLUTIONS

 * In vitro testing/assays on compounds and formulations for the cosmetics,
   pharma, medical device, chemical, and food industries
 * Harmonised data integration supporting IATAs (EdelweissData™)
 * Pre-clinical safety testing
 * Formulation assessments
 * Toxicological and regulatory expertise and advice
 * Safety Assessments and Regulatory Affairs
 * HepaRG™ cell lines and applications for hepatotoxicity testing
 * IATA for skin sensitisation (SaferSkin™)
 * Skin discs and product testing for skin tolerance and irritation
 * Text mining and aggregation to deliver actionable insights (Taxila™)
 * Machine learning and AI applied to data analysis

Learn More


SAFERWORLDBYDESIGN PRODUCTS

SaferSkin™ platform
 * An easy-to-use application based on OECD defined and industry tested
   approaches to predict the skin sensitisation potential of ingredients.
   SaferSkin™ assesses input data and assigns a sensitisation category and the
   level of confidence in the prediction.
 * A complete range of assays and reports.
 * Tests on volunteers.

Learn More
EdelweissData™

A platform for harmonised data integration, supporting the use of multiple
datasets with seamless sharing of data and metadata. EdelweissData™ prepares,
curates, harmonises, standardises and brings together data from different
formats, different sources, and different labs.

 * - EdelweissData in the Lab
   (https://saferworldbydesign.com/edelweissdata/use-cases/case-2/): organise
   your data workflow.
 * - EdelweissData Sharing
   (https://saferworldbydesign.com/edelweissdata/use-cases/case-1/): integrate
   and harmonise project-driven data from multiple users and in different
   formats.
 * - EdelweissData Predictive Modelling
   (https://saferworldbydesign.com/edelweissdata/use-cases/case-3/): integrate
   your data to make predictions.

Learn More
HepaRG™

HepaRG™ is a well-established hepatic cell system. It is truly unique in its
ability to produce early hepatic progenitor cells as well as completely mature
human hepatocytes. They are economical, convenient, and available either under
their stem cell status and good to be expanded and differentiated in-house, or
as cryopreserved, fully differentiated and ready-to-use hepatic cells. HepaRG™
applications include in vitro ADME testing, inhibition assays, drug metabolism
and clearance, cholestasis, virology (HBV, HCV) and viral infection.

Learn More


SaferWorldbyDesign

SaferWorldbyDesign integrates in silico and in vitro methods to develop standard
and premium Integrated Approaches to Testing and Assessment (IATAs), including
methods that support ingredient and formulation screening and testing, product
design and the preparation of Regulatory Dossiers.

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