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VISUALIZE PD1/PD-L1
INTERACTIONS

The first commercial in situ assays out! Detect the PD1/PD-L1 interactions, and
analyze phosphorylated PD1, both assays are based on our NaveniTM Proximity
Ligation Technology READ MORE


THE ART OF PROTEIN SCIENCE

Visualization of protein-protein interactions and post-translational
modifications directly in tissue and cells with Naveni next-generation proximity
ligation technology. OUR PRODUCTS

14.09.2022

HERE TO MAKE A DIFFERENCE – THE FIRST PD1/PD-L1 INTERACTION ASSAY



22.08.2022

LOW SIGNAL AND MULTIPLE NON-SPECIFIC BANDS IN YOUR WESTERN BLOT? LEARN HOW TO
SURPASS THE PROBLEMS



12.07.2022

NAVINCI DIAGNOSTICS AB ANNOUNCES CLOSING OF SEK 90M SERIES A FINANCING, LED BY
SEGULAH MEDICAL ACCELERATION WITH SUPPORT FROM EXISTING SHAREHOLDERS






WELCOME TO NAVINCI

Navinci has a proud history as developers of the first commercial in
situ Proximity Ligation Assays. The Proximity Ligation Technology can be used to
monitor interactions or modifications of endogenous proteins directly in
individual cells and tissues, to reveal the cellular and molecular architecture
and its response to disturbances. The Naveni TM Proximity Ligation Assays are
based on a new, proprietary technology providing higher sensitivity and less
unspecific background than traditional Proximity Ligation Assay.

About us



BRINGING PRECISION TO SPATIAL PROTEOMICS

The Naveni proximity ligation platform pushes the boundaries of
fluorescence-based in situ methodology, enabling researchers to get the maximum
information from every analysis by localizing and quantifying proteins, their
interactions and modifications, in situ at the molecular level. Increased
sensitivity compared to conventional in situ proximity ligation assay, enables
detection of very low abundant proteins and ensures that proteins can be
investigated without the need to over-express, or in any way modify the native
environment of the cell.

Our Platform






FLEXIBLE KITS



FLEXIBLE PRODUCTS TO BE USED WITH YOUR PRIMARY ANTIBODIES 

All our kits are based on the novel, proprietary Naveni™ Proximity Ligation
Technology, which enables precise detection of proteins, protein-protein
interactions, or protein modifications in cultured cells fresh-frozen and FFPE
samples. The flexible in situ kits contain secondary detection reagents called
Navenibodies. The Navenibodies can be used with one or two primary IgG
antibodies.  

NaveniFlexTM kits for visualization of your target with fluorescence readout 

NaveniBrightTM kits for visualization of your target with chromogenic readout 

To our Flexible products 


TARGET-SPECIFIC KITS



TARGET-SPECIFIC PRODUCTS – PRIMARY ANTIBODY SYSTEM INCLUDED 

Our target-specific kits are based on the proprietary Naveni™ Proximity Ligation
Technology, including carefully selected and validated Navenibodies with
specific target protein detection. No extra antibodies are needed; the assay is
already optimized.

Naveni PPI (protein-protein interactions) kits are optimized to detect protein
interactions of validated targets. Naveni PD1/PD-L1 is a specific kit for the
precise and sensitive detection of the PD1 and PD-L1 interaction in human
tissue.

Naveni PTM (post-translational modifications) kits are optimized to detect
phosphorylated proteins. Six products are currently available in this range:
Naveni pY HER2, Naveni pY PDGFR-beta, Naveni pY EGFR, Naveni pY MET, Naveni pY
VEGFR2 and Naveni pY PD1.  

To our Target-specific products 




PHARMA SERVICE



CUSTOM SOLUTIONS TO FIT YOUR RESEARCH NEEDS        

Do you have specific research questions, or do you need help with a
target-specific assay? Please get in touch with us; we have additional support
and services to suit your research project’s needs and requirements. 
Contact us for more information





“To my impression it is a lot better than every other PLA we have done before.
The negative controls are nearly blank for the first time ever. This is a huge
advantage of your kit because this was the main point with which we always
struggled when analyzing the assay in a quantitative way”.

DR. STEFAN PUSCH,

Department of Neuropathology at Heidelberg University


Contact us

Phone: +46 730214726
Email: contact@navinci.se

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