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NEPHROLOGY TIMES

Nephrology Times delivers the latest news in kidney-related treatments and
technologies with the goal of better informing care decisions and improving
patient outcomes.

AKI
CKD
Diabetes and Hypertension
Gout
Hyperkalemia
IgAN
Transplantation
SC0062 Effective and Safe in Patients With IgA Nephropathy

In patients with IgA nephropathy (IgAN) there are associations between both
endothelin-1 upregulation and endothelin receptor type A (ETA) activation and
proteinuria, inflammation, and fibrosis. The 2-SUCCEED trial was designed to
identify the efficacy, safety, and optimal doses of SC0062 for the treatment of
patients with IgAN (NCT05687890). During a late-breaking oral session at ASN
Kidney Week 2024, Hiddo Jan L. Heerspink, PhD, PharmD, reported results of the
phase 2, randomized, placebo-controlled, double-blind trial. The presentation
was titled SC0062, a New Selective Endothelin Receptor Type A Antagonist in IgA
Nephropathy. ...
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The Importance of Long-Term Treatment of Hyperkalemia


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LATEST NEWS

SC0062 Effective and Safe in Patients With IgA Nephropathy
Victoria SochaASN Kidney Week 2024 | November 6, 2024
A novel endothelin receptor type A selective antagonist showed a meaningful
reduction in proteinuria in patients with IgAN.
Novo Nordisk Drops Ocedurenone After Trial Failure and Financial Losses
Charlotte RobinsonChronic Kidney Disease | November 6, 2024
Novo Nordisk will terminate development of ocedurenone for treatment of
hypertension in chronic kidney disease.
Kidney Transplant Collaborative Criticizes CMS Delay of IOTA Payment Model
Charlotte RobinsonKidney Transplantation | November 6, 2024
The Kidney Transplant Collaborative called on CMS to prioritize the IOTA payment
model to improve transplant access.
Pig Kidney Survives Transatlantic Flight
Charlotte RobinsonKidney Transplantation | November 6, 2024
Using X-Therma preservation products, a pig kidney preserved at subzero
temperatures survived a transatlantic flight.
Final Results of the IGNAZ Study of Felzartamab for IgA Nephropathy
Victoria SochaASN Kidney Week 2024 | November 5, 2024
Treatment of IgA nephropathy with felzartamab led to sustained proteinuria
reduction and reduced eGFR decline.
Dr. Jonathan Barratt on Sibeprenlimab for IgAN
Jonathan Barratt, PhDASN Kidney Week 2024 | November 6, 2024
Jonathan Barratt discussed his research on the anti-APRIL antibody sibeprenlimab
in the treatment of IgA nephropathy.
Bone Findings in Transplant Recipients With Gout
Abdul Abdellatif, MDASN Kidney Week 2024 | November 5, 2024
Abdul Abdellatif discussed findings from the PROTECT study examining pegloticase
for kidney transplant patients with gout.
Drug Stewardship in CKD
Charlotte RobinsonChronic Kidney Disease | November 5, 2024
Drug stewardship to ensure the safety and effectiveness of medications is
especially important in patients with CKD.
Hurricane Helene Impacts Dialysis
Charlotte RobinsonNephrology Times | November 5, 2024
Hurricane damage at Baxter's North Carolina facility continues to impact
peritoneal dialysis fluid supplies.
Results of Open-Label Extension of the ORIGIN Phase 2b Study of Atacicept 
Victoria SochaASN Kidney Week 2024 | November 4, 2024
BAFF and APRIL inhibitor atacicept reduced UPCR, hematuria, and Gd-IgA1 and
stabilized eGFR in patients with IgAN.
View More


EXPERT INTERVIEWS

Bone Findings in Transplant Recipients With GoutNovember 5, 2024
Unknown Causes of Kidney Disease ProjectSeptember 26, 2024
ANNA and Nephrology NursingSeptember 4, 2024
Role of Patient Activation in Kidney HealthAugust 27, 2024
Dr. Jonathan Barratt on Sibeprenlimab for IgANNovember 6, 2024
Bone Findings in Transplant Recipients With GoutNovember 5, 2024
Unknown Causes of Kidney Disease ProjectSeptember 26, 2024
ANNA and Nephrology NursingSeptember 4, 2024
Role of Patient Activation in Kidney HealthAugust 27, 2024
Dr. Jonathan Barratt on Sibeprenlimab for IgANNovember 6, 2024
Bone Findings in Transplant Recipients With GoutNovember 5, 2024
Unknown Causes of Kidney Disease ProjectSeptember 26, 2024
ANNA and Nephrology NursingSeptember 4, 2024
Role of Patient Activation in Kidney HealthAugust 27, 2024
 * 1
 * 2
 * 3
 * 4
 * 5

Dr. Jonathan Barratt on Sibeprenlimab for IgANNovember 6, 2024
Bone Findings in Transplant Recipients With GoutNovember 5, 2024
Unknown Causes of Kidney Disease ProjectSeptember 26, 2024
ANNA and Nephrology NursingSeptember 4, 2024
More Interviews


IN PRINT

September/October 2024
Tribute to Nicoloas Madias, amino acid infusion to reduce AKI risk, felzartamab
results, and more.
July/August 2024
American Transplant Congress, 61st ERA Congress, AKI risk prediction, effects of
a lifestyle intervention, and more.
View Full Archive of Past Issues


CONFERENCES

ASN Kidney Week 2024
The American Society of Nephrology's annual meeting to highlight the latest
scientific and medical advances in the field
American Transplant Congress 2024
ATC provides a forum for exchange of new scientific and clinical information
relevant to transplantation.
ERA Congress 2024
The annual nephrology meeting organized by the European Renal Association
NKF Spring Clinical Meetings 2024
The National Kidney Foundation's premier educational event designed for the
interprofessional kidney health team
View Past Conference Coverage


PODCASTS

Clinical Use of Diuretics: Chapter 15 Part 2
Channel Your EnthusiasmNephrology Times | September 13, 2024
Listen to the second part of the discussion of Chapter 15 of Dr. Burton Rose's
book, focused on diuretics.
The KDIGO CKD 2024 Guideline Draft
Freely FilteredNephrology Times | August 2, 2024
It's time for another NephJC draft! This time the 2024 KDIGO CKD guideline draft
is on the clock!
Nefecon for IgAN, The NefIgArd Part B Trial
Freely FilteredNephrology Times | June 18, 2024
Results of Nefecon (budesonide) for IgA nephropathy set the stage for a
glomerulonephritis renaissance.
The Spice Must FLOW!
Freely FilteredNephrology Times | September 13, 2024
Vlado Perkovic presented results from the FLOW trial at the 61st ERA Congress,
making headlines worldwide.
More Episodes


EXPERT COLUMNS

Critical Financial Shifts Ahead: How CY 2025 ESRD PPS Changes Could Impact Small
Dialysis Facilities
Sarah TolsonFrom the Field | October 2, 2024
Sarah Tolson reviews the key financial implications of the CMS proposed rule for
the ESRD Prospective Payment System.
You Will Be Greatly Missed, Nick Madias
Ajay K. Singh, MBBS, FRCP, MBAFrom the Chair | September 27, 2024
Ajay Singh pays tribute to the late nephrologist and researcher Nicolaos Madias,
MD, of Tufts Medical Center.
Go With the Flow
Ajay K. Singh, MBBS, FRCP, MBAFrom the Chair | August 23, 2024
The four-pillar approach to treating diabetic kidney disease (DKD) has been
endorsed by high-quality trials, such as FLOW. 
Navigating the Aftermath: Mitigating Risks From Clearinghouse Disruptions in
Renal Care
Sarah TolsonFrom the Field | June 17, 2024
It is essential for nephrology practices and dialysis centers to have backup
methods for processing claims.
Update on IgA Nephropathy Treatment: Several Newer Therapies on the Horizon
Ajay K. Singh, MBBS, FRCP, MBAIgA Nephropathy | August 23, 2024
IgA nephropathy (IgAN) is on the cusp of a transformational change in its
treatment.
The Dialysis Dilemma: Navigating the Rough Waters of Medicare Advantage Plans
Sarah TolsonFrom the Field | August 23, 2024
Medicare Advantage plans are posing significant operational and financial
hurdles for dialysis programs.
Read More


KNOWLEDGE HUBS

ACUTE KIDNEY INJURY

ADPKD

ANEMIA AND KIDNEY DISEASE

CHRONIC KIDNEY DISEASE

COVID-19 AND KIDNEY DISEASE

DIABETES AND HYPERTENSION

END-STAGE RENAL DISEASE

GOUT

HYPERKALEMIA

IGA NEPHROPATHY

KIDNEY TRANSPLANTATION

METABOLIC ACIDOSIS

ACUTE KIDNEY INJURY

ADPKD

ANEMIA AND KIDNEY DISEASE

CHRONIC KIDNEY DISEASE

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Nephrology Times Chair

--------------------------------------------------------------------------------

Ajay K. Singh, MBBS, FRCP, MBASenior Nephrologist, Brigham and Women’s Hospital
| Senior Associate Dean, Harvard Medical School
Editorial Board

--------------------------------------------------------------------------------

Mohamed G. Atta, MD, MPHProfessor of Medicine, Johns Hopkins School of Medicine
Timothy E. Bunchman, MDProfessor and Director, Pediatric Nephrology,
Transplantation, and Rheumatology, Children’s Hospital of Richmond at VCU
Suphamai Bunnapradist, MD, MSProfessor of Medicine, David Geffen School of
Medicine at UCLA | Research Director, Kidney Transplant Program, UCLA
Fernando C. Fervenza, MD, PhDProfessor of Medicine, Division of Nephrology and
Hypertension, Mayo Clinic
Kenneth A. Liss, DOPartner, Hypertension and Nephrology Association, Eatontown,
NJ
Joel M. Topf, MD, FACPAssistant Clinical Professor of Medicine, Oakland
University William Beaumont School of Medicine

630 Madison Ave.

Manalapan, NJ 07726


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