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PROPECIA: A NUMBER ONE REMEDY FOR HAIR LOSS


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Table of Contents:

 * Why Is Propecia a Number One Remedy for Hair Loss?
 * What Is Alopecia?
 * Causes of Alopecia
 * Propecia: What Is It and How Does It Work?
 * What Is the Effect of Propecia on Body?
 * Propecia: Test Results
 * Efficiency of Propecia
 * Why Should Propecia Be Taken for a Long Time?
 * Composition
 * Propecia Contraindications
 * Propecia Instructions to Use
 * Propecia Shelf Life
 * Frequently Asked Questions about Propecia

--------------------------------------------------------------------------------

Propecia is developed for those who do not want to be reconciled with hair loss
affecting their look and countenance. This drug works flawlessly improving hair
follicles and making you forget about alopecia forever.



WHY IS PROPECIA A NUMBER ONE REMEDY FOR HAIR LOSS?

Propecia is a drug for men and women treating alopecia and reducing hair loss.
Regular hair loss is one of the most common problems of modern men and women.
Hundreds of men all over the world suffer from alopecia that can occur both at a
young and elderly age.

In some cases, hair loss is accompanied by severe nervous stress or
overexcitation, in others it is the result of previous diseases of
cardiovascular system or bad hereditary predisposition. Anyway, there is no
reason to worry about hair loss, because in the beginning of the 21st century a
way out of this situation was found and named Propecia. It copes well with not
only its direct purpose, but also struggles against issues caused by genetic
predisposition to the development of this alopecia. Propecia provides perfect
results in a few months.




WHAT IS ALOPECIA?

Alopecia - this word came to us from Ancient Greece denoting baldness. This term
in medicine refers to hair loss that is pathological in nature and causes
complete loss of hair, or its significant thinning in large areas of scalp or
trunk.

Among the widespread types of this disease is called focal, symptomatic,
scarring, and finally, androgenetic alopecia. On this latter we will dwell in
detail, as it develops under the influence of dihydrotestosterone (DHT), the
active form of the sex hormone in men, and is responsible for more than 95% of
cases of baldness in the stronger sex. Hair follicles contain 5-alpha-reductase,
an enzyme that interacts with testosterone that leads to follicle dystrophy
beginning to produce short and colorless hair. Such vegetation is already unable
to cover certain areas of the head, there is a noticeable bald patch.

The hair follicle of women also contains 5-alpha-reductase, but the male sex
hormone in the female body is present in a much smaller amount, and DHT is
formed less. Androgenetic alopecia in the weaker sex has a less pronounced
clinical picture, affecting mainly the central areas of the head, the so-called
“parting”. On the lateral surfaces of a woman's head, thinning and hair loss is
not so extensive, while baldness in men is more noticeable, as androgenetic
alopecia is more prone to parietal and frontal areas of the head. This is
explained by the fact that not all hair follicles are equally sensitive to male
sex hormones. This indicator is strictly individual for each person, but it is
in these zones that the most sensitive dihydrotestosterone follicles are
located.

It is well known that human hair is constantly renovated. With the loss of about
fifty or even a hundred and fifty hairs a day, organism makes up for the loss,
and this replacement is imperceptible and painless for the body. Visually,
unnecessary hair loss becomes visible only after losing 15% of hair. And this is
an occasion to sound the alarm and take urgent measures to save hair. To prevent
a serious hair loss, you should pay attention to intensity of hair loss: daily
amount remaining on the comb or in bath tub after washing your head, the
quantity of thinning areas or even bald spots. Abundant loss of hair while
combing and thinning hair are the first signs of alopecia.

Do not rely on the prevailing view that the appearance of a man does not matter
for women. This statement was invented earlier, when there were no effective
ways to combat hair loss, and there was nothing else to do but to reconcile with
the situation. Science does not stand still. Our medicine claims that you can
and should fight with such a cosmetic problem as baldness. Although bald head
does not cause physical discomfort to its owner, it strongly changes his
appearance. It goes without saying that you can get used to your new
countenance, if necessary, change photos on documents, and enjoy life. But if
you are experiencing psychological discomfort, do not agree to put up with this
state of affairs and want to fight for your fluffy head of hair, modern medicine
is ready to offer you an excellent drug that will help solve the problem of
baldness, Propecia.




CAUSES OF ALOPECIA

Alopecia is a disease characterized by hair loss on head and impairment new hair
growth.

At present, the following types of disease are described in the medical
literature:

 * Focal alopecia (in other words, circular alopecia);
 * Alopecia areata;
 * Alopecia occurring after a traumatic situation;
 * Diffuse alopecia;
 * Alopecia based on hereditary factors;
 * Androgenic alopecia;
 * Seborrheic alopecia;
 * Alopecia, accompanied by scar formation (cicatricial alopecia).

Etiology of some forms of this disease is not completely studied; therefore,
alopecia is considered to be a multifactorial disease. The risk of focal
alopecia may lie in stressful situations, prolonged intoxication or autoimmune
processes. Hair loss can also develop due to unfavorable heredity or as a result
of a traumatic situation, due to pulling out of hair during a fight, a game,
etc. Alopecia can cause constriction of hair when styling them in a hairdo. The
appearance of cosmetic alopecia with frequent use of crimpers for straightening
or curling hair and application of hot hair stylers.

The cause of alopecia can be hormonal disorders as well. An imbalance of
androgens and estrogens can cause the development of so-called androgenic
alopecia and is manifested in a mild form in men, is not a cause for concern and
is not considered a pathological process. In women, such a violation of the
ratio of hormones can be the cause of increased production of androgens by
adrenals or ovaries.

A consequence of prolonged intoxication, chronic poisoning, long-lasting severe
infectious diseases can be diffuse alopecia. This pathology often accompanies
the course of pregnancy. Alopecia can be transmitted from generation to
generation. In this case, it is a hereditary disorder. Most often, the type of
inheritance is autosomal recessive, but in some cases, an autosomal dominant
type of transmission of genetic information is also uncovered.

If alopecia is caused by destruction of the hair follicles due to the appearance
of scar tissue on skin, then this pathology should be attributed to cicatricial
alopecia. Various skin injuries (burns, exposure to radiation), manifestation of
some infectious diseases, such as syphilis, tuberculosis, leishmaniasis, or
tumor growth may cause scar alopecia.




PROPECIA: WHAT IS IT AND HOW DOES IT WORK?

Propecia (finasteride) is a modern preparation that appeared not so long ago on
world pharmaceutical markets but has already received a lot of positive reviews.
The reception of finasteride is a drug therapy is the most accessible form of
combating baldness, along with such approaches to treatment as laser therapy and
hair transplantation.

Propecia received the approval of the European Medicines Agency and was
recommended by the US Food and Drug Administration (FDA) which confirmed the
clinical efficacy and safety of this drug. Earlier, in addition to Propecia,
approval of these organizations received only one drug for alopecia – minoxidil
that was originally created to treat hypertension.

Propecia is a unique drug. These are the first tablets in the world effectively
eliminating the problem of baldness. Efficiency and duration of impact on
treatment of androgenetic alopecia with Propecia is much higher than the one of
minoxidil. Thus, now these tablets are called “a number two medicine” for men
legging behind the leader of sales - Viagra.

After successful clinical trials, the popularity of Propecia is steadily
growing. As already noted, the active substance of Propecia is finasteride which
became widespread in 1992 when it was used in medical practice for the treatment
of prostatic hyperplasia. Men who received the treatment of baldness with
finasteride began to note the increase in hair growth on forehead and head.




WHAT IS THE EFFECT OF PROPECIA ON BODY?

The thing is that the excess of dihydrotestosterone, one of the male hormones
needed at the stage of development and maturation of the male body, leads to
alopecia with age. The accumulation of DHT in hair follicles leads to their
dystrophy and gradual narrowing and causes termination of hair growth its
further death. For the formation of dihydrotestosterone, 5-alpha-reductase is
necessary and the active substance of Propecia, being an inhibitor of this
enzyme, prevents the formation of DHT in hair follicles and allows successfully
to combat the cause of baldness. Decrease in DHT level better affects the
structure and condition of hair. It acquires a healthy look and the ability to
grow and replace and restore fallen hair.




PROPECIA: TEST RESULTS

Clinical studies confirm the high efficacy of Propecia. According to clinical
trials, under 90% of men noticed that their hair stopped falling out. A year
later, half of the patients resumed their hair growth. And after 18 months, the
percentage of men whose hair acquired a “second life” rose to 66%. Propecia
provides tremendous results: it restores hair follicles on the crown and
eliminates bald patches on forehead ideally coping with the so-called male
pattern of alopecia. Before Propecia was developed, it was thought that these
areas of the head are the least treatable, since it is there that hair follicles
are sensitive to the effects of the male sex hormone. This drug with proven
effectiveness returns hair to men.




EFFICIENCY OF PROPECIA

As for the treatment of female androgenetic alopecia, Propecia could be just as
effective, but its main active ingredient, finasteride, increases the likelihood
of congenital anomalies in fetus in pregnant women. This circumstance forced the
development company Merck & Co. Inc. to categorically prohibit the use of
Propecia by women of childbearing age.

Since finasteride is really effective in combating hair loss, it is becoming
increasingly popular all over the world. It is noteworthy that the regular
reception of finasteride leads to the renewal of follicles that produce cannula
hair and stimulates the growth of full-fledged real hair. It is quite natural
that the final results can be different depending on the individual
characteristics of the human body.

Until now, it was believed that to cure androgenetic alopecia with one hundred
percent effectiveness is possible only in women. The effectiveness of drug
therapy for men is usually determined by stages of the disease according to the
Norwood scale from I to VII, and it is recommended to begin treatment of
baldness as early as possible in order to achieve a better effect. As research
has shown, even in advanced cases of disease, the use of Propecia allows, if not
to return the lost hair completely, then at least completely prevent further
baldness, and keep the remaining amount of hair.

If you have patience and perseverance, repeat treatment courses, a year later,
or a little more, you can leave problems with alopecia in the past, and admire a
much more lush and thick hairstyle.




WHY SHOULD PROPECIA BE TAKEN FOR A LONG TIME?

The development of DHT hormone begins to get blocked immediately after the
beginning of therapy course. However, damaged hair follicles need time to
restore normal functioning. Even healthy hair grows very slowly, about 1 cm per
month, so to replace thinning hair and get visible improvement a several-months
therapy with finasteride is required. Therefore, Propecia should be taken daily
within the course of three months or longer. Termination of therapy can often be
accompanied by relapses, it is better to immediately adjust to a long and
successful treatment of alopecia. In case you forgot to take the medicine, just
skip this day and continue the course of treatment with initial dosage.
Unauthorized increase in assigned dose of the drug is unacceptable, as it
accelerates the risk of side-effects. Gradually, you will begin to notice
improvements and after about halfway through a year you will see healthy
newly-grown hair that will return a young and fresh appearance.




COMPOSITION

Propecia is a medicinal product that includes the active substance, finasteride
(1 mg). Finasteride is an inhibitor of the enzyme the main function of which is
conversion of testosterone to dihydrotestosterone. This substance was in demand
in 1990s when specialists in the urological practice started medical treatment
of hyperplasia.

In addition to the main substance, the composition contains auxiliary
components, including magnesium stearate, microcrystalline cellulose, corn
starch, sodium starch, lauryl macrogol glyceride.

Propecia is produced in the form of small capsules of octagonal shape. The cost
of tablets varies due to the number of capsules in the package.




PROPECIA CONTRAINDICATIONS

Propecia is prohibited to pregnant and lactating women. Due to the presence of a
large number of HMG-CoA reductase inhibitors in the female body, testosterone is
not able to get transformed into an active element provoking occurrence of some
abnormalities in the reproductive system of fetus. The drug is contraindicative
to children and aged people. Moreover, if you have a hypersensitivity to use of
substances in the composition of Propecia, refuse the usage of this drug.

Side-effects of tablets include:

 1. Sharp decrease in libido
 2. Erectile dysfunction
 3. Occurrence of symptoms of erectile issues
 4. Reducing semen amount




PROPECIA INSTRUCTIONS TO USE

The effect of taking this medication is experienced only in case of its regular
use. Take Propecia tablet one time a day (not fasted) with a lot of warm water.
The daily dose should be established by direct examination of the patient by his
or her attending physician.

Do not self-medicate, since the misuse of generic drugs can give quite an
opposite effect. Usually the duration of the therapeutic course takes 3 to 6
months without interruption. The duration of treatment depends on the individual
characteristics of a particular patient’s organism, as well as on the growth
rate of his hair. After therapy course termination, hair returns to its original
state for the next few months.




PROPECIA SHELF LIFE

In order to get the expected effect and tangible results, it is necessary to
take Propecia by carefully following all the instructions and prescriptions. If
you have not previously used this drug, it is better to consult a qualified
specialist who can analyze your problem, identify the causes of it, and
prescribe an effective therapy course.

With regard to storage conditions, the product should be stored in a dark and
cool room, the air temperature of which should not exceed 20-30 degrees Celsius.
Store Propecia away from children.




FREQUENTLY ASKED QUESTIONS ABOUT PROPECIA

DESCRIBE BRIEFLY WHAT THE PURPOSE OF PROPECIA IS...

Propecia is a drug designed to treat hair loss and baldness in men and in men
only. Propecia is available in the form of tablets that must be administered not
oftener than once a day.

WHAT FORMS OF HAIR LOSS DOES PROPECIA TREAT?

Propecia is designed to treat only androgenic forms of alopecia (synonyms: male
pattern baldness, hereditary alopecia). About 95% of all cases of baldness
belong to this type. The drug is not intended for treatment of other forms of
alopecia: focal alopecia (nest alopecia), baldness caused by a lack of vitamins
and nutrients, etc. The nature of these forms of alopecia is completely
different than androgenic alopecia, and there will be little or no benefit from
Propecia administration.

CAN WOMEN TAKE PROPECIA?

No, the use of Propecia by women is strictly forbidden, since this can lead to
serious side-effects.

IN WHAT FORMS IS THE DRUG PRODUCED?

Propecia is available in tableted form. The shape and type of tablets may vary.
As a rule, the tablets have brownish tinge, octagonal shape and coating.
Generally, the tablets are placed in plastic vials of different shapes and
designs depending on manufacturer. Vials can in turn be packaged in kits
designed for treatment course 1, 2, 3 and more months.

WHAT IS THE COMPOSITION OF PROPECIA?

The active component of Propecia is finasteride which was approved for use under
the name Proscar in 1992 for the treatment of prostatic hyperplasia. Propecia
tablets contain 1 mg of finasteride.

WHAT EFFECTS SHOULD I EXPECT FROM PROPECIA’S ADMINISTRATION?

Propecia usually gives very good results allowing you to restore hair growth not
only on the top of head, but also in the area of the frontal bald patches. These
areas are usually difficult to treat. Effectiveness of Propecia in struggle
against alopecia is evidenced by the fact that approximately 66% of men who took
Propecia not only preserved the amount of hair on the same or increased level,
but also had a significant number of new hair instead of the fallen out. These
results were achieved by different patients quite naturally. The most important
thing that is proved by clinical trials is that the vast majority of patients
using Propecia have completely retained the amount of hair up to now.

HOW FAST SHOULD WE EXPECT RESULTS?

Although Propecia begins to block the formation of dihydrotestosterone (DHT)
immediately after the beginning of its application, it takes time to start the
hair growth. It should be remembered that healthy hair grows in average a
centimeter per month; therefore, it takes time to discover a visible
improvement. According to clinical studies, it is necessary to take Propecia
daily for 3 months or longer so that the effect becomes noticeable – slowing
down and stopping the process of hair loss. After 6 months of Propecia
administration, you can observe growing hair instead of falling out and it will
not be just a fluff, but real hair. If Propecia did not work for twelve months,
its further application is most likely impractical.

HOW LONG SHOULD I TAKE PROPECIA?

You need to take Propecia as long as you want to keep your hair, continue their
recovery and increase the amount. If you stop using Propecia, you will most
likely lose the previously restored hair for about 12 months. It is worth
remembering that the role played by Propecia in blocking the formation of
dihydrotestosterone (DHT). With termination of Propecia course, this hormone
will begin its destructive impact on hair again.

WHAT ARE THE POSSIBLE SIDE-EFFECTS OF PROPECIA?

Side-effects noted in the clinical trials were rare and did not concern most
men. In about 0.5% of cases, men experienced any of the following side-effects
related to sexual sphere: decrease in libido (decreased sexual desire),
difficulty in achieving erection, reduction in the number of germ cells.
Side-effects completely disappeared in men who stopped taking Propecia.

WHAT IS THE POSSIBILITY RATE OF FINASTERIDE OCCURRENCE IN SEMEN?

Special clinical studies were conducted on this topic. The presence of
finasteride in semen was monitored in 35 men on the daily basis for 6 months of
Propecia administration. In 60% of cases Propecia in semen was not found at all.
The highest level was 1.52 nanograms/ml. If we assume that the level of
finasteride in semen will always be the highest detected level and that a
woman's vagina occurs daily 100 % absorption of the dose of ejaculate 5 ml, it
turns out that the human body is exposed to a dose that is 750 times less than
in experiments with rhesus monkeys - classic laboratory animals.

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