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Location in Punjab, Pakistan. This article needs additional citations for
verification. Please help improve this article by adding citations to reliable
sources. Unsourced material may be challenged and removed. Retrieved 4 May
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In third world countries like Pakistan, most of the barbers are illiterate and
unaware of transmission of infectious agents through the repeated use of razors
and scissors for different customers without sterilizing them first [ 82 ].
Circumcision is a very important religious procedure performed during early
infancy both in rural and urban areas, and the barber community performing this
procedure are mostly unaware of transmission of hepatitis by contaminated
instruments [ 84 ].

In the Pakistani population there was moderate knowledge about HCV infection
whereas awareness about various HCV risk factors was very low [ 31 , 86 , 87 ].
In a survey conducted at a family medicine clinic in Karachi, most of the
participants had some educational background and were living in Karachi city.

Zuberi et al [ 88 ] reported that knowledge about HCV infection was related to
the educational background of the participants.

Public awareness programs are required to decrease the future burden of HCV
infection in the Pakistani population. HCV is classified into eleven different
genotypes, of which six are the major genotypes and these genotypes are further
classified into many subtypes [ 89 , 90 ]. The most detailed study was conducted
by Idrees and Riazuddin in , who performed genotyping of patients and reported
that genotype 3a was the most prevalent genotype in Pakistan; their results are
summarized in Figure 1 [ 95 ].


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This study reviewed the seroprevalence of HCV among various population groups,
along with risk factors and genotypes in Pakistan. High prevalence was observed
in IDUs and the multi-transfused population, suggesting that the reuse of
syringes was common among the injecting drug users, and that blood transfusions
were not properly screened.

The majority of HCV-positive patients had a history of facial and armpit shaving
by barbers suggesting that the barbers shop was the key place for viral
transmission. Condom usage was very low among the commercial sex workers and
there was low awareness about sexually transmitted diseases amongst this group.
In Pakistan, the number of estimated injections per person per year was very
high because most Pakistanis think that injectable drugs are more efficacious
than oral drugs.

There was low awareness in people about the various risk factors associated with
HCV transmission. More emphasis should be given to the preventive measures of
the disease in order to decrease the future health and economic burden; these
include screened blood transfusions, proper sterilization techniques in clinics
and hospitals, use of disposable syringes and razor blades. The government
should take aggressive steps to create awareness among the general public by the
use of media or by modifying the school syllabus.

Advanced Search. This Article. Citation of this article. Hepatitis C virus in
Pakistan: A systematic review of prevalence, genotypes and risk factors.

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All rights reserved. World J Gastroenterol. Flaviviridae: the viruses and their
replication. Fields virology. Philadelphia: Lippincott-Raven Publishers ; Wands
JR. Prevention of hepatocellular carcinoma. N Engl J Med. Clinical Update -
Debio in Hepatitis C. Accessed April, Centers for Disease Control and
Prevention. World Health Organization.

Department of Measurement and Health Information. United Nations Development
Program. Human Development Report New York: Oxford University Press ;. PSG
consensus statement on management of hepatitis C virus infection J Pak Med
Assoc. An autoregressive integrated moving average model for short-term
prediction of hepatitis C virus seropositivity among male volunteer blood donors
in Karachi, Pakistan.

The relationship between therapeutic injections and high prevalence of hepatitis
C infection in Hafizabad, Pakistan. Epidemiol Infect. J Clin Gastroenterol.
General seroprevalence of hepatitis C and hepatitis B virus infections in
population. J Coll Physicians Surg Pak. Pak J Med Res. Zaman R. J Med Sci.
Frequency of Hepatitis B and C in central Punjab. Pak J Pathol. Pak J Med Sci.
Libyan J Med. Hepatitis A, B and C seroprevalence in Pakistan. Indian J Pediatr.
Khan HI. A study of seroprevalence of hepatitis B and C in mothers and children
in Lahore.

Pak Ped J. Detection of antibodies to hepatitis C virus in dried blood spot
samples from mothers and their offspring in Lahore, Pakistan.

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