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COLUMBIA UNIVERSITY • DEPARTMENT OF
PHYSIOLOGY AND CELLULAR BIOPHYSICS

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MISSION STATEMENT >



" As the mysteries of the human genome are revealed it is ever more important to
understand the functional consequences of genetic variants. Physiology provides
the key to unlock these mysteries and bring us to future new understandings that
will alleviate human miseries."

> Multiple Awards in the Shaun Liu Lab

— Andrew Marks

> Congratulations to Professor Filippo Mancia for being named a Foreign Member
   of Academia das Ciências de Lisboa

> 2024 Departmental RETREAT 



Honoring Pioneering Neuroscientist
Eric Kandel 



Henry Colecraft and the
Case of the Scientist and Entrepreneur

Columbia University in NYC

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RESEARCH AREAS


NEUROBIOLOGY

Uncovering the biological mechanisms by which nervous systems mediate behavior.
Research in the neurobiology focus area spans molecular, cellular, circuit, and
systems level physiology to understand the development and function of the
nervous system, and mechanisms that contribute to neurological and
neuropsychiatric diseases.


STRUCTURAL BIOLOGY

Unraveling principles that govern structure and function of macro-molecules.
Research in the Structural Biology focus area uses state-of-the-art technologies
such as cryo-electron microscopy to probe structure and function of biological
macromolecules, particularly membrane proteins, at near-atomic resolution.


CARDIOVASCULAR PHYSIOLOGY

Unveiling fundamental mechanisms underlying heart function and heart disease.
Research in the Cardiovascular Physiology focus area includes fundamental
investigation of cardio-vascular biology, identifying mechanisms of
cardiovascular dysfunction in heart failure, cardiac arrhythmias, and
atherosclerosis, as well as developing new translational approaches to treat
life-threatening heart disease.


INTEGRATED PHYSIOLOGY

Understanding cellular and systems physiology. Research in the Integrated
Physiology focus area spans a wide-range of cutting-edge topics including
metabolism and mitochondrial function, pulmonary biology, bone biology, skeletal
muscle function, and virology. A major thrust is to attain a systems level
understanding of human physiology and human disease leveraging emerging omics
technologies.

Departmental Address

 Department of Physiology & Cellular Biophysics
Columbia University College of Physicians & Surgeons
Russ Berrie Pavilion
1150 St. Nicholas Ave., Room 508
New York, NY 10032 

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