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JDRF, the type 1 diabetes charity•Connect Immune Research


CONNECT IMMUNE RESEARCH

A new scientific challenge. A new opportunity for charities to increase impact.

We and our partners are presenting the scientific community with an unanswered
challenge. Can they collaborate across disease-specific silos to tackle many
conditions at once?

Their response could transform lives, and transform them much faster than small
groups of specialists working in parallel could possibly achieve.

The type 1 diabetes charity JDRF, the MS Society, Versus Arthritis and the
British Society for Immunology want to know how immune disorders are linked. To
be more specific, ‘what are the common mechanisms of autoimmunity and immune
mediated inflammation?’

We want to build momentum among funders and scientists to find the answer by
working together in a way that rarely happens across different immune disorders
today.

We are calling our project Connect Immune Research.


WHY ARE WE DOING THIS?

As the type 1 diabetes charity, JDRF wants the answer for one reason: so that we
can prevent type 1 diabetes from happening and find the cure, faster, for the
400,000 UK people living with it.

But the answer could also allow our partners to prevent and cure a whole range
of other autoimmune and inflammatory conditions, which together affect
approximately four million Britons.

(Left to right) JDRF’s Director of Research Partnerships Rachel Connor, MS
Society’s Senior Research Manager David Coutts and Versus Arthritis’ Head of
Research Awards and Translation Caroline Aylott


BROADENING THE FOCUS. BUILDING A COALITION.

There are a large number of autoimmune and inflammatory conditions known to
science. They include type 1 diabetes, Crohn’s disease, colitis, MS, psoriasis
and rheumatoid arthritis.

We know there are similarities in the genetic risk factors for many of these
conditions. We know that many people live with more than one of them – for
example thirty three per cent of people diagnosed with type 1 diabetes have at
least one other autoimmune disorder at diagnosis – they are much more likely to
have Coeliac disease or Hashimoto’s thyroiditis than the general population.

So it is well established that the conditions are linked in some way. But for
too long, investigating researchers have not been. They have had limited
opportunities to collaborate.

By working with scientists with expertise in different conditions, we could
discover that one treatment in a single condition is a skeleton key, unlocking
impact far beyond the initial indication. This could also dramatically reduce
costs and speed transformation of treatment for millions of people.


THAT’S WHY WE’RE BUILDING JDRF’S CONNECT IMMUNE RESEARCH INITIATIVE.

We will start by funding a pilot collaborative award – we want scientists from
different immune-related specialties to come together in a consortium to begin
uncovering the common threads between their work. We want them to explore how to
build progress in individual fields into faster progress across many fields.


WHAT IS THE EMERGING CONNECT IMMUNE RESEARCH COALITION?

JDRF, Versus Arthritis and MS Society committed to the pilot initiative along
with the backing of the British Society of Immunology.

As the initiative develops further and begins to deliver some results, we are
keen for other organisations with an interest in research related to other
autoimmune conditions to join this initiative.

To help inform potential partners, we have developed the Connect Immune Research
Charter which explains our vision, strategy and principles but also offers a
tiered membership so that big and small organisations feel that they can join.

We are delighted that Alopecia UK, the Psoriasis and Psoriatic Arthritis
Alliance (PAPAA), Coeliac UK, Bowel Research UK, the British Thyroid Foundation,
the Royal Free Charity and myaware have since joined the Connect Immune Research
initiative.


WHAT IS THE LORNA AND YUTI CHERNAJOVSKY BIOMEDICAL RESEARCH FOUNDATION AND
CONNECT IMMUNE RESEARCH PARTNERSHIP?

In 2022, we announced that ten new autoimmunity research projects would receive
nearly £1 million from the partnership of the Lorna and Yuti Chernajovsky
Biomedical Research Foundation and Connect Immune Research.

The ten new 12-month pilot projects will explore how to target the links between
multiple autoimmune conditions to increase our understanding and generate new
treatments.

The ultimate aim of this initiative is to deliver significant new investment to
confront the UK’s high prevalence of autoimmunity and develop new treatments for
multiple autoimmune conditions, faster.

Read more about this announcement, or find out about the ten pilot projects.


READ THE CONNECT IMMUNE RESEARCH PRESS RELEASE

Read our public announcement of this groundbreaking initiative.


DOWNLOAD THE ARE YOU #AUTOIMMUNEAWARE? REPORT



Are You #AutoimmuneAware? from Connect Immune Research reveals the increase in
autoimmune conditions and highlights the need for greater recognition and
investment for autoimmunity as a distinct research area.


FOR FURTHER INFORMATION

Please contact connect@jdrf.org.uk


DISCOVER OUR RESEARCH



Browse our world-class research projects that will transform the lives of people
with type 1 diabetes - improving treatments until we find the cure



Our research


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JDRF, THE TYPE 1 DIABETES CHARITY

We fund research to cure, treat and prevent type 1. We work with government,
academia and industry to accelerate research in the UK and within healthcare
policy to ensure that the outcomes of research are delivered to people with type
1 in the UK. And we give support and a voice to people with type 1 and their
families. Join us in creating a world without type 1 diabetes.


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Copyright © 2022 | Juvenile Diabetes Research Foundation Ltd (JDRF) is a charity
registered in England and Wales (No. 295716) and in Scotland (No. SC040123).
Registered address: 17/18 Angel Gate, City Road, London EC1V 2PT. Tel: 020 7713
2030. Registered as a company limited by guarantee, in England and Wales (No
2071638).



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KEEP IN TOUCH

We'd love to keep you updated about our work to cure, treat and prevent type 1
diabetes, and how we support people with type 1. We'd also like to let you know
how you can help by donating, volunteering or campaigning.

We may stay in touch by post or phone if we have those details from you, but it
keeps our costs down if we can use email, meaning that we can invest more money
in ground breaking type 1 research.

Please let us know if you're happy for us to contact you by email:


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No, I don't want to receive emails from JDRF

To change how we contact you, or to stop all contact from us, please phone 020
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Your privacy is important to us. Please read our privacy policy.


OUR SUPPORTER PROMISE

We promise that we will treat you and your personal information with the utmost
care and respect.Please read our supporter promise.