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 * Rapamycin

Rapamycin
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Rapamycin or Rapacan (Sirolimus)
(0 Customer reviews)


RAPAMYCIN OR RAPACAN (SIROLIMUS)

(0 Customer reviews)

Rapamycin (Rapacan) is an immunosuppressant with antifungal and antitumor
effects. It has a suppressive effect on the immune system. It is effective in
cases where it is necessary to suppress its activity to avoid some diseases or
rejection of donor organs.

According to some data, the drug's active ingredient, Sirolimus, and the
rapamycin supplement may positively affect older people's health, helping
prolong life, but confirming this requires additional studies.

Hide

Active Ingredient: Sirolimus

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RAPAMYCIN

1mg
 * 1mg 10 pills
   
   £47.47 £49.85
   
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 * 1mg 20 pills
   
   £85.37 £89.64
   
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 * 1mg 30 + 2 pills
   
   £133.30 £139.97
   
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 * 1mg 60 + 4 pills
   
   £264.41 £277.63
   
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 * 1mg 90 + 6 pills
   
   £391.69 £411.28
   
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 * 1mg 120 + 10 pills
   
   £523.74 £549.93
   
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 * 1mg 180 + 10 pills
   
   £757.34 £795.20
   
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 * 1mg 270 + 10 pills
   
   £1104.11 £1159.32
   
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 * 1mg 360 + 20 pills
   
   £1478.94 £1552.89
   
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Descriptions


DRUG INFO

 * Brand Names: Rapamune, Rapamycin, Rapacan;
 * Active Ingredient: Sirolimus;
 * Manufacturer: Pfizer, Biocon.


RAPAMYCIN (RAPACAN) AND ITS ACTIVE SUBSTANCE SIROLIMUS

Rapamycin (or Rapacan) is a pill containing the active ingredient Sirolimus. For
treatment with the drug to be effective, you should follow the instructions or
doctor's recommendations.

After you take the tablet, the active substance Sirolimus gets into the blood
and has these effects:

 * Blocking cell growth;
 * Blocking cell reproduction;
 * Suppressing the immune system.

ATTENTION! Overdosing on Rapamycin may lead to hazardous results. Don't take the
drug without a doctor's prescription.


INDICATIONS FOR USE

The main indications of Rapamycin (Rapacan) are tumor treatment and elimination
of possible donor organ rejection. The EMA approved the use of the drug in the
following cases:

 * Preventing donor organ rejection after kidney transplantation in adults;
 * Treating sporadic lymphangioleiomyomatosis with moderate lung damage.


TREATMENT REGIMENS AND DOSAGES

The treatment regimens and dosages of Rapamycin depend on the purpose of its
use. The drug is available in a dosage of 1 mg. A doctor may prescribe more than
one tablet at a time.

 * After transplantation, a single dosage of 6 mg is usually prescribed. After
   that, you switch to a daily dosage of 2 mg until the required therapeutic
   level of the active substance in the blood is achieved. Next, the dosage is
   calculated individually, and the treatment duration is 2–3 months.
 * For the treatment of sporadic lymphangioleiomyomatosis, the usual starting
   dosage is 2 mg per day. After 10 - 20 days, when the therapeutic level of the
   active substance is reached in the blood, the dosage should be adjusted
   depending on individual characteristics.

Before adjusting the drug dosage, you should have special tests to determine the
level of the active substance in the blood. Dosage adjustments are also
necessary for:

 * Black people due to high immunological risk;
 * People with liver dysfunction.

Currently, there is not enough data to confirm that the response of people over
65 years to the drug may differ from that of younger people. The drug's safety
for children and people under 18 has also yet to be proven. So, a doctor should
decide on dosage adjustments based on individual characteristics and the
advisability of using Rapamycin in each particular case.


RECOMMENDATIONS FOR USE

Rapamycin (Rapacan) 1 mg is available as tablets. To get the most out of
Rapamycin treatment, follow these rules:

 * Take the medication at the same time every day;
 * Take the pill with plenty of water;
 * Take the drug before or after meals;
 * Avoid grapefruit juice.

Although the data on combining alcohol and Rapamycin are insufficient, to
prevent adverse effects, we recommend avoiding alcohol for the entire period of
treatment with the drug.

Also, when using the Rapamycin supplement, you should avoid fatty foods. This is
because fats reduce the absorption rate of the drug's active ingredient. St.
John's wort can lower the blood concentration of the active substance. Avoid
medicines containing St. John's wort during treatment.


MISSED DOSE

If you miss a dose of Rapamycin, take it as soon as possible. If it is near time
for your next dose, skip the previous dose and continue treatment as scheduled.


PRECAUTIONS

In some cases, using Rapamycin may have a higher risk and be contraindicated. A
doctor will not prescribe the drug in the following cases:

 * You are pregnant or breastfeeding;
 * You have an increased sensitivity to the active ingredient;
 * You had a liver or lung transplantation.

Considering the immunosuppressive effect of Rapamycin, the risk of contracting
various types of infections increases during its use. Avoid contact with sick
people to protect yourself. The immunosuppressive effect of the drug can persist
for 6 months after the end of treatment.

Rapamycin (Rapacan) may increase the risk of bleeding and slow wound healing. Be
careful when using sharp objects and seek immediate medical attention if you
have symptoms such as:

 * Bruises;
 * Black stool;
 * Blood in urine.

According to some data, people with a body mass index greater than 30 kg/m2 may
have an increased risk of impaired wound healing when taking Rapamycin.

The medication reduces the effect of vaccinations. Moreover, Sirolimus may
increase skin sensitivity to the sun. So, always use sunscreen during treatment.


USE OF RAPAMYCIN (RAPACAN) DURING PREGNANCY

Usually, doctors don't prescribe the drug to pregnant women because there is no
data on its safety for them. Animal studies confirm fetal toxicity of Rapamycin.
A doctor should decide on the possible use of the medicine during pregnancy if
it is absolutely necessary.

There is also no evidence that Sirolimus gets into women's breast milk due to
the lack of relevant studies. However, according to some studies, the drug gets
into the milk of animals. So, its use by breastfeeding women can be dangerous
for the child. If you are breastfeeding, avoid using Rapamycin and consult a
doctor.


POSSIBLE SIDE EFFECTS

Like any other drug, Rapamycin may cause side effects. To reduce the likelihood
of side effects, follow the doctor’s instructions and don't exceed the
prescribed dosage. The most common (in 10% of cases) side effects of the
medicine are as follows:

 * Anemia;
 * High pressure;
 * Urinary tract infections;
 * Hypokalemia;
 * Abdominal pain;
 * Swelling;
 * Headache;
 * Diarrhea;
 * Constipation;
 * Nausea.

Most often, the severity of side effects depends on the individual
characteristics and dosage of the medication. If you have severe side effects or
if they get worse over time, consult a doctor.

As a rule, overdosing on the drug causes increased side effects. See a doctor if
you exceed the prescribed dosage, and your condition worsens.


RAPAMYCIN (RAPACAN): INTERACTION WITH OTHER DRUGS

Rapamycin may interact with other medicines. So, you should inform a doctor
about all the drugs you take. When combined with CYP3A4 inhibitors, the
medication may increase the active substance in the blood and cause side
effects. At the same time, CYP3A4 inhibitors reduce Sirolimus levels. Don't use
Rapamycin with these drugs:

 * Rifampicin;
 * Ketoconazole;
 * Voriconazole;
 * Diltiazem;
 * Erythromycin;
 * Cyclosporine.

Grapefruit juice affects CYP3A4-mediated metabolism. So, avoid it in any form.
For more information about possible Rapamycin interactions, consult a doctor or
pharmacist.


STORAGE

Store Rapamycin at room temperature 20 - 25°C in a dark place out of the reach
of children and animals. Don't use the drug if the expiration date has passed or
the packaging is damaged.


THE BEST OFFER FOR RAPAMYCIN ONLINE ON THE MARKET

Proven drugs that provide a guaranteed effect are an important condition for the
safety and effectiveness of treatment. At our pharmacy, you can buy Rapamycin 1
mg, which quality meets all necessary EU standards. Moreover, we offer
attractive prices compared to our competitors. When ordering at our online
pharmacy, you will also get these benefits:

 * Fast delivery;
 * 100% anonymity;
 * 24/7 support;
 * Convenient payment methods (VISA, MasterCard, American Express, or bank
   transfer).

At our pharmacy, you can buy Rapamycin without a prescription, saving time and
getting the opportunity to start treatment immediately. If you need help, you
can contact our experts, who will answer all your questions.


HOW TO BUY RAPAMYCIN 1 MG ONLINE

You can buy Rapamycin 1 mg online in a few minutes at our pharmacy. To do this,
fill out a special order form indicating the following information:

 * Drug name;
 * Dosage;
 * Quantity;
 * Delivery address.

We will quickly complete your order and send it to the specified address. Our
managers are in touch around the clock and will help you in case of any
difficulties. Contact our support team now, and we will help you place your
order.

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