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Submission: On August 24 via manual from KE — Scanned from DE
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* Careers * Investors * Contact * About * Our Platform * Pipeline & Programs * Pipeline OverviewSee the 23andMe Therapeutics pipeline in full * 23ME-00610Clinical-stage therapeutic antibody designed to restore the immune system’s ability to kill cancer cells * 23ME-01473Clinical-stage antibody targeting ULBP6 to induce immune activation through dual mechanisms that may restore anti-tumor immunity. * Collaborations * News & Research * About Us * Our Platform * Pipeline & Programs * Overview * 23ME-00610 * 23ME-01473 * Collaborations * News & Research * Careers * Contact * Investors TOMORROW’S MEDICINES ARE IN OUR GENES. WE ARE AN INTEGRATED CLINICAL-STAGE BIOTECH COMPANY TURNING DATA AT SCALE INTO NEW TREATMENTS FOR PATIENTS. WE TRANSLATE BIOLOGICAL INSIGHTS FROM THE WORLD'S LARGEST RECONTACTABLE HUMAN GENETIC DATABASE INTO POTENTIALLY SIGNIFICANT NEW THERAPIES FOR PATIENTS WITH SERIOUS UNMET NEED, FOCUSING ON CANCER AND IMMUNOLOGICAL AND INFLAMMATORY DISEASES. OUR PLATFORM Powered by the world’s largest recontactable platform of genetic and phenotypic data, and an experienced team with the ability to leverage it, we focus on developing therapeutic antibodies with high-value targets that are central mediators of biological processes. Explore Our Platform CLINICAL PROGRAMS 23andMe Therapeutics has advanced two immuno-oncology programs into the clinic. 23ME-00610 is a first-in-class clinical investigational therapeutic antibody generated in-house and designed to restore the ability of the body’s immune cells to kill cancer cells by blocking the immunosuppressive checkpoint receptor CD200R1. It is currently enrolling the Phase 2a portion of a Phase 1/2a study. 23ME-01473 is an NK cell-activating investigational therapeutic antibody targeting the NKG2D ligand ULBP6. Learn More About Our Pipeline and Programs "We look forward to leveraging our unique database, along with advancements in AI and ML, to further advance therapeutic programs at 23andMe, both independently and with collaborators." Anne Wojcicki CEO & Co-Founder COLLABORATIONS We seek development collaborators to help us realize the full clinical and commercial potential of our immuno-oncology programs. We also seek innovative, future-forward research teams to embark with us on the discovery and early development of novel, genetically validated targets. Lastly, we invite inquiries from teams interested in leveraging our database for in silico discovery partnerships. Collaborate on our I/O clinical assets Help us pursue targets in I&I Learn about leveraging our data for in silico R&D LATEST RESEARCH View All Research 23ME-00610 Research SAFETY, EFFICACY, AND PKPD OF 23ME-00610, A FIRST-IN-CLASS ANTI-CD200R1 ANTIBODY, IN PATIENTS WITH ADVANCED OR... Jun 3, 2024 Read more 23ME-00610 Research SAFETY, EFFICACY, AND PKPD OF 23ME-00610, A FIRST-IN-CLASS ANTI-CD200R1 ANTIBODY, IN PATIENTS WITH ADVANCED NEUROENDOCRINE... Jun 1, 2024 Read more 23ME-01473 Research DISCOVERY OF ULBP6 AS A NOVEL IMMUNO-ONCOLOGY TARGET USING PLEIOTROPIC SIGNALS FROM 23ANDME’S GENETIC AND... Apr 17, 2024 Read more 23ME-01473 Research 23ME-01473, A NOVEL ANTI-ULBP6/2/5 MONOCLONAL ANTIBODY, REINVIGORATES ANTI-TUMOR NK CELL FUNCTION THROUGH NKG2D AND FCΓRIIIA... Apr 8, 2024 Read more 23ME-00610 Research NEW INSIGHTS INTO TARGETING THE CD200R1 PATHWAY IN T AND NK CELLS USING 23ME-00610 AS... Apr 8, 2024 Read more Company Research AN ENGINEERED MOUSE MODEL THAT GENERATES A DIVERSE REPERTOIRE OF ENDOGENOUS, HIGH-AFFINITY COMMON LIGHT CHAIN... Feb 8, 2024 Read more Company Research THE METABOLIC ROLE OF MAP3K15: GENETIC AND PHENOTYPIC INSIGHTS FROM THE 23ANDME RESEARCH DATABASE AND... Jan 10, 2024 Read more Blog Research THE POWER OF SCALE IN DRUG DEVELOPMENT Jan 10, 2024 Read more 23ME-00610 Research FIRST-IN-CLASS ANTI-CD200R1 ANTIBODY 23ME-00610 IN PATIENTS WITH ADVANCED SOLID MALIGNANCIES: PHASE 1 POSTER Nov 3, 2023 Read more * 1 * 2 * 3 SERVICES * Health + Ancestry * Ancestry Service * 23andMe+ Premium * 23andMe+ Total Health * Gifts COMPANY * Investors * About Us * Diversity, Equity, & Inclusion * Media Center * Blog * Genetics Learning Hub * Careers * Refer a Friend * Return Policy * Customer Care * FSA/HSA Eligibility LEGAL * Important Test Info * Terms of Service * Privacy Statement * Data Protection * Family Considerations * Research Consent * Individual Data Consent * Biobanking Consent * Cookie Policy * Cookie Choices * Patent Information * Report a Security Issue * Consumer Health Data Privacy Policy PARTNER WITH US * Healthcare Professionals * Education * Scientists * Therapeutics DOWNLOAD APP DOWNLOAD APP ©2024 23andMe, Inc. All rights reserved. RECENT NEWS Safety, efficacy, and PKPD of 23ME-00610, a first-in-class anti-CD200R1 antibody, in patients with advanced neuroendocrine cancers. Learn more RECENT NEWS 23andMe Therapeutics Announces Positive Preliminary Phase 2 Safety and Efficacy Results for 23ME-00610, targeting CD200R1, at the 2024 ASCO Annual Mee Learn more RECENT NEWS Safety, efficacy, and PKPD of 23ME-00610, a first-in-class anti-CD200R1 antibody, in patients with advanced or metastatic ovarian cancer. Learn more RECENT NEWS Safety, efficacy, and PKPD of 23ME-00610, a first-in-class anti-CD200R1 antibody, in patients with advanced neuroendocrine cancers. Learn more RECENT NEWS 23andMe Therapeutics Announces Positive Preliminary Phase 2 Safety and Efficacy Results for 23ME-00610, targeting CD200R1, at the 2024 ASCO Annual Mee Learn more RECENT NEWS Safety, efficacy, and PKPD of 23ME-00610, a first-in-class anti-CD200R1 antibody, in patients with advanced or metastatic ovarian cancer. Learn more RECENT NEWS Safety, efficacy, and PKPD of 23ME-00610, a first-in-class anti-CD200R1 antibody, in patients with advanced neuroendocrine cancers. Learn more * 1 * 2 * 3