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Jump to navigation * Full Prescribing Information * Full Prescribing Information * Información Completa de Prescripción * Patient Information * Patient Information * Información Para el Paciente * Important Safety Information * Información de seguridad importante * Indications * Indicaciones * Healthcare Professionals * Healthcare Professionals https://www.ibrance.com/financial-support-resources?src_code=IBRW10031130 Live Support 1-844-9-IBRANCE Materiales en Español * For Newly Diagnosed * Understanding MBC * About IBRANCE * Starting & Taking IBRANCE * IBRANCE Tablets * Real Stories * Share Your Story * Savings Resources * Patient & Caregiver Resources * Talking With Your Doctor * Additional Support Resources * Tips On Living With MBC * Resources To Download * Caregiver Resources SIGN UP SIGN UP Materiales en Español Healthcare Professionals * Home * Savings Resources https://www.ibrance.com/financial-support-resources?src_code=IBRW10031130 Live Support 1-844-9-IBRANCE Materiales en Español * For Newly Diagnosed * Understanding MBC * About IBRANCE * Starting & Taking IBRANCE * IBRANCE Tablets * Real Stories * Share Your Story * Savings Resources * Patient & Caregiver Resources * Talking With Your Doctor * Additional Support Resources * Tips On Living With MBC * Resources To Download * Caregiver Resources SIGN UP SIGN UP Materiales en Español Healthcare Professionals Financial Support MAKING YOUR SUPPORT NEEDS A PRIORITY. TOGETHER. Pfizer Oncology TogetherTM is a personalized support program to help you and your loved ones throughout IBRANCE treatment. We can work with you to help identify financial assistance options for your prescribed IBRANCE. And if you need help with some of the day-to-day challenges you're facing, we can connect you to a dedicated Care Champion who has social work experience and will offer you support resources. Because when it comes to support, we're in this together. For live personalized support, call 1-844-9-IBRANCE. * Commercially Insured * Medicare Or Government Insured * Uninsured COMMERCIALLY INSURED? Resources for eligible patients with commercial, private, employer, or state health insurance marketplace coverage. CO-PAY ASSISTANCE Eligible, commercially insured patients may pay as little as $0 per month for IBRANCE. Limits, terms, and conditions apply.* There are no income requirements, forms, or faxing to enroll. SIGN UP *Patients are not eligible to use this card if they are enrolled in a state or federally funded insurance program, including but not limited to Medicare, Medicaid, TRICARE, Veterans Affairs health care, a state prescription drug assistance program, or the Government Health Insurance Plan available in Puerto Rico. Patients may receive up to $25,000 in savings annually. The offer will be accepted only at participating pharmacies. This offer is not health insurance. No membership fees apply. Pfizer reserves the right to rescind, revoke, or amend this offer without notice. For full terms and conditions, please see PfizerOncologyTogether.com/terms. For any questions, please call 1-844-9-IBRANCE, visit PfizerOncologyTogether.com/terms or write: Pfizer Oncology Together Co-Pay Savings Program, 2250 Perimeter Park Drive, Suite 300, Morrisville, NC 27560. †Data current as of March 2019. Individual out-of-pocket cost will vary depending on plan. ON MEDICARE OR GOVERNMENT INSURANCE? Help identifying resources for eligible patients with Medicare/Medicare Part D, Medicaid, and other government insurance plans: * Assistance with searching for financial support that may be available from independent charitable foundations. These foundations exist independently of Pfizer and have their own eligibility criteria and application processes. Availability of support from the foundations is determined solely by the foundations * Financial assistance through Extra Help, a Medicare Part D Low-Income Subsidy (LIS) program * Free medicine* *If support from independent charitable foundations or Medicare Extra Help is not available, Pfizer Oncology Together will provide eligible patients with medication for free through the Pfizer Patient Assistance Program. The Pfizer Patient Assistance Program is a joint program of Pfizer Inc. and the Pfizer Patient Assistance Foundation™. The Pfizer Patient Assistance Foundation is a separate legal entity from Pfizer Inc. with distinct legal restrictions. †Data current as of March 2019. Individual out-of-pocket cost will vary depending on plan. UNINSURED? Help identifying resources for eligible patients without any form of healthcare coverage: * Help finding coverage * Free medicine through the Pfizer Patient Assistance Program, or at a savings through the Pfizer Savings Program* *The Pfizer Savings Program is not health insurance. For more information, call the toll-free number 1-844-9-IBRANCE. There are no membership fees to participate in this program. Estimated savings are 50% and depend on such factors as the particular drug purchased, amount purchased, and the pharmacy where purchased. Additional pricing information can be found at IBRANCEPricing.com. TO GET STARTED WITH PFIZER SUPPORT RESOURCES: FOR LIVE, PERSONALIZED SUPPORT Call 1-844-9-IBRANCE (Monday–Friday 8 AM–8 PM ET) SIGN UP A diagnosis of mBC takes support. We’re here to help. ACCESS PATIENT & CAREGIVER RESOURCES Terms and Conditions By using this co-pay card, you acknowledge that you currently meet the eligibility criteria and will comply with the Terms and Conditions described below: * Patients are not eligible to use this card if they are enrolled in a state or federally funded insurance program, including but not limited to Medicare, Medicaid, TRICARE, Veterans Affairs health care, a state prescription drug assistance program, or the Government Health Insurance Plan available in Puerto Rico (formerly known as “La Reforma de Salud”). * Patient must have private insurance. Offer is not valid for cash-paying patients. * With this card, eligible patients will pay a $0 co-pay per eligible monthly prescription, subject to a maximum amount of $25,000 per calendar year. The amount of any benefit is the difference between your co-pay and $0. After the annual maximum of $25,000 is reached, you will be responsible for the remaining monthly out-of-pocket costs. This card may not be redeemed more than once per 30 days. * This co-pay card is not valid when the entire cost of your prescription drug is eligible to be reimbursed by your private insurance plan or other private health or pharmacy benefit programs. * You must deduct the value of this co-pay card from any reimbursement request submitted to your insurance plan, either directly by you or on your behalf. * You are responsible for reporting use of the co-pay card to any private insurer, health plan, or other third party who pays for or reimburses any part of the prescription filled using the co-pay card, as may be required. You should not use the co-pay card if your insurer or health plan prohibits use of manufacturer co-pay cards. * You must be 18 years of age or older to redeem the co-pay card. * This co-pay card is not valid where prohibited by law. * Card cannot be combined with any other savings, free trial, or similar offer for the specified prescription. * Card will be accepted only at participating pharmacies. * This card is not health insurance. * Offer good only in the U.S. and Puerto Rico. * Card is limited to 1 per person during this offering period and is not transferable. * No other purchase is necessary. * Data related to your redemption of the co-pay card may be collected, analyzed, and shared with Pfizer for market research and other purposes related to assessing Pfizer's programs. Data shared with Pfizer will be aggregated and de-identified; it will be combined with data related to other co-pay card redemptions and will not identify you. * Pfizer reserves the right to rescind, revoke, or amend this offer without notice. * Offer expires 12/31/2022. * If your pharmacy does not participate, you may be able to submit a request for a rebate in connection with this offer. Mail a copy of the patient's pharmacy receipt indicating patient name, name of medication purchased, price paid, and date purchased, along with a copy of the patient's Pfizer Oncology Together Co-Pay Savings Card, to: Pfizer Oncology Together Co-Pay Savings Program 2250 Perimeter Park Drive, Suite 300 Morrisville, NC 27560 Turn to Pfizer Oncology Together to learn about financial assistance resources and get personalized support from one of our dedicated Care Champions. Acuda a Pfizer Oncology Together para obtener más información sobre los recursos de asistencia financiera y obtener apoyo personalizado de uno de nuestros Campeones de Atención especializados. CALL 1-844-9-IBRANCE (Monday–Friday 8 AM–8 PM ET) VISIT PfizerOncologyTogether.com LLAME AL 1-844-9-IBRANCE (De lunes a viernes de 8:00 a 20:00 h, hora del este) VISITE PfizerOncologyTogether.com Turn to Pfizer Oncology Together to learn about financial assistance resources and get personalized support from one of our dedicated Care Champions. Acuda a Pfizer Oncology Together para obtener más información sobre los recursos de asistencia financiera y obtener apoyo personalizado de uno de nuestros Campeones de Atención especializados. CALL 1-844-9-IBRANCE (Monday–Friday 8 AM–8 PM ET) VISIT PfizerOncologyTogether.com LLAME AL 1-844-9-IBRANCE (De lunes a viernes de 8:00 a 20:00 h, hora del este) VISITE PfizerOncologyTogether.com IMPORTANT SAFETY INFORMATION & INDICATIONS INDICACIONES E INFORMACIÓN DE SEGURIDAD IMPORTANTE IBRANCE may cause serious side effects, including: Low white blood cell counts (neutropenia). Low white blood cell counts are very common when taking IBRANCE and may cause serious infections that can lead to death. Your doctor should check your white blood cell counts before and during treatment. If you develop low white blood cell counts during treatment with IBRANCE, your doctor may stop your treatment, decrease your dose, or may tell you to wait to begin your treatment cycle. Tell your doctor right away if you have signs and symptoms of low white blood cell counts or infections such as fever and chills. Lung problems (pneumonitis). IBRANCE may cause severe inflammation of the lungs during treatment that can lead to death. Tell your doctor right away if you have any new or worsening symptoms, including: * chest pain * cough with or without mucus * trouble breathing or shortness of breath Your doctor may interrupt or stop treatment with IBRANCE completely if your symptoms are severe. Before you take IBRANCE, tell your doctor about all of your medical conditions, including if you: * have fever, chills, or any other signs or symptoms of infection. * have liver or kidney problems. * are pregnant or plan to become pregnant; IBRANCE can harm your unborn baby. * Females who are able to become pregnant should use effective birth control during treatment and for at least 3 weeks after the last dose of IBRANCE. Your doctor may ask you to take a pregnancy test before you start treatment with IBRANCE. * Males with female partners who can become pregnant should use effective birth control during treatment with IBRANCE for at least 3 months after the last dose of IBRANCE. * are breastfeeding or plan to breastfeed. It is not known if IBRANCE passes into your breast milk. Do not breastfeed during treatment with IBRANCE and for 3 weeks after the last dose. The most common side effects of IBRANCE include: * Low red blood cell counts and low platelet counts. Call your doctor right away if you develop any of these symptoms during treatment: * dizziness * shortness of breath * weakness * bleeding or bruising more easily * nosebleeds * infections * tiredness * nausea * sore mouth * abnormalities in liver blood tests * diarrhea * hair thinning or hair loss * vomiting * rash * loss of appetite IBRANCE may cause fertility problems in males. This may affect your ability to father a child. Talk to your healthcare provider about family planning options before starting IBRANCE if this is a concern for you. These are not all of the possible side effects of IBRANCE. For more information, ask your doctor. Tell your doctor about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. IBRANCE and other medicines may affect each other, causing side effects. Do not drink grapefruit juice or eat grapefruit products while taking IBRANCE as they may increase the amount of IBRANCE in your blood. Tell your doctor if you start a new medicine. Take IBRANCE exactly as your doctor tells you. If you take too much IBRANCE, call your doctor right away or go to the nearest hospital emergency room. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088. INDICATIONS IBRANCE 125 mg capsules and tablets are a prescription medicine used in adults to treat hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) breast cancer that has spread to other parts of the body (metastatic) in combination with: IBRANCE is a prescription medicine used in adults to treat hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) breast cancer that has spread to other parts of the body (metastatic) in combination with: * an aromatase inhibitor as the first hormonal based therapy in postmenopausal women or in men, or * fulvestrant in people with disease progression following hormonal therapy. Please see Full Prescribing Information and Patient Information. Please see Full Prescribing Information and Patient Information. IBRANCE puede causar efectos secundarios graves, entre ellos: Recuentos bajos de glóbulos blancos (neutropenia). Los recuentos bajos de glóbulos blancos son muy frecuentes cuando se toma IBRANCE y pueden causar infecciones graves que pueden provocar la muerte. Su médico debe verificar sus recuentos de glóbulos blancos antes y durante el tratamiento. Si presenta recuentos bajos de glóbulos blancos durante el tratamiento con IBRANCE, el médico puede interrumpir el tratamiento, disminuir la dosis o indicarle que espere para comenzar el ciclo de tratamiento. Comuníquele de inmediato a su médico si presenta signos y síntomas de recuentos bajos de glóbulos blancos o de infecciones, como fiebre y escalofríos. Problemas pulmonares (neumonitis). IBRANCE puede provocar una inflamación de los pulmones grave o potencialmente fatal durante el tratamiento y puede conducir a la muerte. Informe a su profesional médico de inmediato si tiene algún síntoma nuevo o si sus síntomas empeoran, que incluyen: * dolor de pecho * tos con o sin flema * dificultad para respirar o falta de aire Su médico puede interrumpir o detener por completo el tratamiento con IBRANCE si sus síntomas son intensos. Antes de tomar IBRANCE, informe a su médico todas sus afecciones médicas, incluyendo si: * tiene fiebre, escalofríos o cualquier otro signo o síntoma de infección. * tiene problemas hepáticos o renales. * está embarazada o planea embarazarse; IBRANCE puede hacer daño a su bebé por nacer. * Las mujeres con capacidad de quedar embarazadas deben utilizar un método anticonceptivo eficaz durante el tratamiento y, como mínimo, durante 3 semanas después de tomar la última dosis de IBRANCE. Es posible que su médico le pida someterse a una prueba de embarazo antes de iniciar el tratamiento con IBRANCE. * Los hombres que tengan parejas del sexo femenino que puedan quedar embarazadas deben utilizar un método anticonceptivo eficaz durante el tratamiento con IBRANCE y, como mínimo, durante 3 meses después de tomar la última dosis de IBRANCE. * está amamantando o planea hacerlo. Se desconoce si IBRANCE se excreta en la leche materna. No amamante mientras esté en tratamiento con IBRANCE ni durante 3 semanas después de tomar la última dosis. Los efectos secundarios más frecuentes de IBRANCE incluyen: * Bajos recuentos de glóbulos rojos y bajos recuentos de plaquetas. Llame de inmediato a su médico si presenta cualquiera de estos síntomas durante el tratamiento: * mareos * falta de aliento * debilidad * sangrado o formación de moretones con más facilidad * sangrado nasal * infecciones * cansancio * náuseas * llagas en la boca * anomalías en las pruebas de función hepática * diarrea * afinamiento o caída del cabello * vómitos * sarpullido * pérdida del apetito IBRANCE puede causar problemas de fertilidad en los hombres. Esto puede afectar su capacidad de engendrar un hijo. Si esto le preocupa, antes de tomar IBRANCE hable con su proveedor de atención médica sobre sus opciones de planificación familiar. Estos no son todos los posibles efectos secundarios de IBRANCE. Para obtener más información, consulte a su médico. Informe a su médico sobre todos los medicamentos que toma, incluidos los medicamentos de venta con receta y los de venta libre, vitaminas y suplementos a base de hierbas. IBRANCE y otros medicamentos pueden afectarse mutuamente, causando efectos secundarios. No beba jugo de toronja ni coma productos a base de toronja mientras toma IBRANCE, ya que pueden aumentar la cantidad de IBRANCE en la sangre. Informe a su médico si comienza a tomar un nuevo medicamento. Tome IBRANCE exactamente como se lo indique su médico. Si toma una dosis demasiado alta de IBRANCE, llame de inmediato a su médico o acuda a urgencias del hospital más cercano. Le recomendamos que informe los eventos adversos relacionados con los productos de Pfizer llamando al 1-800-438-1985 (EE. UU. únicamente). Si lo prefiere, puede comunicarse directamente con la Administración de Medicamentos y Alimentos de los EE. UU. (Food and Drug Administration, FDA). Visite www.fda.gov/medwatch o llame al 1-800-FDA-1088. (EE. UU. únicamente). INDICACIONES IBRANCE cápsulas y comprimidos de 125 mg son un medicamento de venta con receta que se utiliza en adultos para el tratamiento del cáncer de mama con receptor hormonal positivo (HR+) y receptor 2 del factor de crecimiento epidérmico humano negativo (HER2-) que se ha propagado a otras partes del cuerpo (metastásico) en combinación con: * un inhibidor de la aromatasa como primera terapia hormonal en mujeres posmenopáusicas o en hombres, o bien, * fulvestrant en personas con progresión de la enfermedad después de la terapia hormonal. Consulte la Información Completa de Prescripción y la Información Para el Paciente. Consulte la Información Completa de Prescripción y la Información Para el Paciente. * Terms of Use * Privacy Policy * Contact Pfizer * Site Map * Sign Up You are encouraged to report adverse events related to Pfizer products by calling 1-800-438-1985 (U.S. only). If you prefer, you may contact the U.S. Food and Drug Administration (FDA) directly. Visit http://www.fda.gov/MedWatch or call 1-800-FDA-1088. This site is intended only for U.S. residents. The products discussed in this site may have different product labeling in different countries. The information provided is for educational purposes only and is not intended to replace discussions with a healthcare provider. © 2022 Pfizer Inc. All rights reserved. Pfizer, PO Box 29387, Mission, KS 66201 March 2022 PP-IBR-USA-4908 Turn to Pfizer Oncology Together to learn about financial assistance resources and get personalized support from one of our dedicated Care Champions. CALL 1-844-9-IBRANCE (Monday–Friday 8 AM–8 PM ET) VISIT PfizerOncologyTogether.com IMPORTANT SAFETY INFORMATION & INDICATIONS INDICACIONES E INFORMACIÓN DE SEGURIDAD IMPORTANTE IMPORTANT SAFETY INFORMATION & INDICATIONS INDICACIONES E INFORMACIÓN DE SEGURIDAD IMPORTANTE view more Ver Más close cerca IBRANCE may cause serious side effects, including: Low white blood cell counts (neutropenia). Low white blood cell counts are very common when taking IBRANCE and may cause serious infections that can lead to death. Your doctor should check your white blood cell counts before and during treatment. If you develop low white blood cell counts during treatment with IBRANCE, your doctor may stop your treatment, decrease your dose, or may tell you to wait to begin your treatment cycle. Tell your doctor right away if you have signs and symptoms of low white blood cell counts or infections such as fever and chills. Lung problems (pneumonitis). IBRANCE may cause severe inflammation of the lungs during treatment that can lead to death. Tell your doctor right away if you have any new or worsening symptoms, including: * chest pain * cough with or without mucus * trouble breathing or shortness of breath Your doctor may interrupt or stop treatment with IBRANCE completely if your symptoms are severe. Before you take IBRANCE, tell your doctor about all of your medical conditions, including if you: * have fever, chills, or any other signs or symptoms of infection. * have liver or kidney problems. * are pregnant or plan to become pregnant; IBRANCE can harm your unborn baby. * Females who are able to become pregnant should use effective birth control during treatment and for at least 3 weeks after the last dose of IBRANCE. Your doctor may ask you to take a pregnancy test before you start treatment with IBRANCE. * Males with female partners who can become pregnant should use effective birth control during treatment with IBRANCE for at least 3 months after the last dose of IBRANCE. * are breastfeeding or plan to breastfeed. It is not known if IBRANCE passes into your breast milk. Do not breastfeed during treatment with IBRANCE and for 3 weeks after the last dose. The most common side effects of IBRANCE include: * Low red blood cell counts and low platelet counts. Call your doctor right away if you develop any of these symptoms during treatment: * dizziness * shortness of breath * weakness * bleeding or bruising more easily * nosebleeds * infections * tiredness * nausea * sore mouth * abnormalities in liver blood tests * diarrhea * hair thinning or hair loss * vomiting * rash * loss of appetite IBRANCE may cause fertility problems in males. This may affect your ability to father a child. Talk to your healthcare provider about family planning options before starting IBRANCE if this is a concern for you. These are not all of the possible side effects of IBRANCE. For more information, ask your doctor. Tell your doctor about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. IBRANCE and other medicines may affect each other, causing side effects. Do not drink grapefruit juice or eat grapefruit products while taking IBRANCE as they may increase the amount of IBRANCE in your blood. Tell your doctor if you start a new medicine. Take IBRANCE exactly as your doctor tells you. If you take too much IBRANCE, call your doctor right away or go to the nearest hospital emergency room. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088. INDICATIONS IBRANCE 125 mg capsules and tablets are a prescription medicine used in adults to treat hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) breast cancer that has spread to other parts of the body (metastatic) in combination with: IBRANCE is a prescription medicine used in adults to treat hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) breast cancer that has spread to other parts of the body (metastatic) in combination with: * an aromatase inhibitor as the first hormonal based therapy in postmenopausal women or in men, or * fulvestrant in people with disease progression following hormonal therapy. Please see Full Prescribing Information and Patient Information. Please see Full Prescribing Information and Patient Information. IBRANCE puede causar efectos secundarios graves, entre ellos: Recuentos bajos de glóbulos blancos (neutropenia). Los recuentos bajos de glóbulos blancos son muy frecuentes cuando se toma IBRANCE y pueden causar infecciones graves que pueden provocar la muerte. Su médico debe verificar sus recuentos de glóbulos blancos antes y durante el tratamiento. Si presenta recuentos bajos de glóbulos blancos durante el tratamiento con IBRANCE, el médico puede interrumpir el tratamiento, disminuir la dosis o indicarle que espere para comenzar el ciclo de tratamiento. Comuníquele de inmediato a su médico si presenta signos y síntomas de recuentos bajos de glóbulos blancos o de infecciones, como fiebre y escalofríos. Problemas pulmonares (neumonitis). IBRANCE puede provocar una inflamación de los pulmones grave o potencialmente fatal durante el tratamiento y puede conducir a la muerte. Informe a su profesional médico de inmediato si tiene algún síntoma nuevo o si sus síntomas empeoran, que incluyen: * dolor de pecho * tos con o sin flema * dificultad para respirar o falta de aire Su médico puede interrumpir o detener por completo el tratamiento con IBRANCE si sus síntomas son intensos. Antes de tomar IBRANCE, informe a su médico todas sus afecciones médicas, incluyendo si: * tiene fiebre, escalofríos o cualquier otro signo o síntoma de infección. * tiene problemas hepáticos o renales. * está embarazada o planea embarazarse; IBRANCE puede hacer daño a su bebé por nacer. * Las mujeres con capacidad de quedar embarazadas deben utilizar un método anticonceptivo eficaz durante el tratamiento y, como mínimo, durante 3 semanas después de tomar la última dosis de IBRANCE. Es posible que su médico le pida someterse a una prueba de embarazo antes de iniciar el tratamiento con IBRANCE. * Los hombres que tengan parejas del sexo femenino que puedan quedar embarazadas deben utilizar un método anticonceptivo eficaz durante el tratamiento con IBRANCE y, como mínimo, durante 3 meses después de tomar la última dosis de IBRANCE. * está amamantando o planea hacerlo. Se desconoce si IBRANCE se excreta en la leche materna. No amamante mientras esté en tratamiento con IBRANCE ni durante 3 semanas después de tomar la última dosis. Los efectos secundarios más frecuentes de IBRANCE incluyen: * Bajos recuentos de glóbulos rojos y bajos recuentos de plaquetas. Llame de inmediato a su médico si presenta cualquiera de estos síntomas durante el tratamiento: * mareos * falta de aliento * debilidad * sangrado o formación de moretones con más facilidad * sangrado nasal * infecciones * cansancio * náuseas * llagas en la boca * anomalías en las pruebas de función hepática * diarrea * afinamiento o caída del cabello * vómitos * sarpullido * pérdida del apetito IBRANCE puede causar problemas de fertilidad en los hombres. Esto puede afectar su capacidad de engendrar un hijo. Si esto le preocupa, antes de tomar IBRANCE hable con su proveedor de atención médica sobre sus opciones de planificación familiar. Estos no son todos los posibles efectos secundarios de IBRANCE. Para obtener más información, consulte a su médico. Informe a su médico sobre todos los medicamentos que toma, incluidos los medicamentos de venta con receta y los de venta libre, vitaminas y suplementos a base de hierbas. IBRANCE y otros medicamentos pueden afectarse mutuamente, causando efectos secundarios. No beba jugo de toronja ni coma productos a base de toronja mientras toma IBRANCE, ya que pueden aumentar la cantidad de IBRANCE en la sangre. Informe a su médico si comienza a tomar un nuevo medicamento. Tome IBRANCE exactamente como se lo indique su médico. Si toma una dosis demasiado alta de IBRANCE, llame de inmediato a su médico o acuda a urgencias del hospital más cercano. Le recomendamos que informe los eventos adversos relacionados con los productos de Pfizer llamando al 1-800-438-1985 (EE. UU. únicamente). Si lo prefiere, puede comunicarse directamente con la Administración de Medicamentos y Alimentos de los EE. UU. (Food and Drug Administration, FDA). Visite www.fda.gov/medwatch o llame al 1-800-FDA-1088. (EE. UU. únicamente). INDICACIONES IBRANCE cápsulas y comprimidos de 125 mg son un medicamento de venta con receta que se utiliza en adultos para el tratamiento del cáncer de mama con receptor hormonal positivo (HR+) y receptor 2 del factor de crecimiento epidérmico humano negativo (HER2-) que se ha propagado a otras partes del cuerpo (metastásico) en combinación con: * un inhibidor de la aromatasa como primera terapia hormonal en mujeres posmenopáusicas o en hombres, o bien, * fulvestrant en personas con progresión de la enfermedad después de la terapia hormonal. Consulte la Información Completa de Prescripción y la Información Para el Paciente. Consulte la Información Completa de Prescripción y la Información Para el Paciente. IMPORTANT SAFETY INFORMATION & INDICATIONS INDICACIONES E INFORMACIÓN DE SEGURIDAD IMPORTANTE IBRANCE may cause serious side effects, including: Low white blood cell counts (neutropenia). Low white blood cell counts are very common when taking IBRANCE and may cause serious infections that can lead to death. Your doctor should check your white blood cell counts before and during treatment. If you develop low white blood cell counts during treatment with IBRANCE, your doctor may stop your treatment, decrease your dose, or may tell you to wait to begin your treatment cycle. Tell your doctor right away if you have signs and symptoms of low white blood cell counts or infections such as fever and chills. Lung problems (pneumonitis). IBRANCE may cause severe inflammation of the lungs during treatment that can lead to death. Tell your doctor right away if you have any new or worsening symptoms, including: * chest pain * cough with or without mucus * trouble breathing or shortness of breath Your doctor may interrupt or stop treatment with IBRANCE completely if your symptoms are severe. Before you take IBRANCE, tell your doctor about all of your medical conditions, including if you: * have fever, chills, or any other signs or symptoms of infection. * have liver or kidney problems. * are pregnant or plan to become pregnant; IBRANCE can harm your unborn baby. * Females who are able to become pregnant should use effective birth control during treatment and for at least 3 weeks after the last dose of IBRANCE. Your doctor may ask you to take a pregnancy test before you start treatment with IBRANCE. * Males with female partners who can become pregnant should use effective birth control during treatment with IBRANCE for at least 3 months after the last dose of IBRANCE. * are breastfeeding or plan to breastfeed. It is not known if IBRANCE passes into your breast milk. Do not breastfeed during treatment with IBRANCE and for 3 weeks after the last dose. The most common side effects of IBRANCE include: * Low red blood cell counts and low platelet counts. Call your doctor right away if you develop any of these symptoms during treatment: * dizziness * shortness of breath * weakness * bleeding or bruising more easily * nosebleeds * infections * tiredness * nausea * sore mouth * abnormalities in liver blood tests * diarrhea * hair thinning or hair loss * vomiting * rash * loss of appetite IBRANCE may cause fertility problems in males. This may affect your ability to father a child. Talk to your healthcare provider about family planning options before starting IBRANCE if this is a concern for you. These are not all of the possible side effects of IBRANCE. For more information, ask your doctor. Tell your doctor about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. IBRANCE and other medicines may affect each other, causing side effects. Do not drink grapefruit juice or eat grapefruit products while taking IBRANCE as they may increase the amount of IBRANCE in your blood. Tell your doctor if you start a new medicine. Take IBRANCE exactly as your doctor tells you. If you take too much IBRANCE, call your doctor right away or go to the nearest hospital emergency room. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088. INDICATIONS IBRANCE 125 mg capsules and tablets are a prescription medicine used in adults to treat hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) breast cancer that has spread to other parts of the body (metastatic) in combination with: IBRANCE is a prescription medicine used in adults to treat hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) breast cancer that has spread to other parts of the body (metastatic) in combination with: * an aromatase inhibitor as the first hormonal based therapy in postmenopausal women or in men, or * fulvestrant in people with disease progression following hormonal therapy. Please see Full Prescribing Information and Patient Information. Please see Full Prescribing Information and Patient Information. IBRANCE puede causar efectos secundarios graves, entre ellos: Recuentos bajos de glóbulos blancos (neutropenia). Los recuentos bajos de glóbulos blancos son muy frecuentes cuando se toma IBRANCE y pueden causar infecciones graves que pueden provocar la muerte. Su médico debe verificar sus recuentos de glóbulos blancos antes y durante el tratamiento. Si presenta recuentos bajos de glóbulos blancos durante el tratamiento con IBRANCE, el médico puede interrumpir el tratamiento, disminuir la dosis o indicarle que espere para comenzar el ciclo de tratamiento. Comuníquele de inmediato a su médico si presenta signos y síntomas de recuentos bajos de glóbulos blancos o de infecciones, como fiebre y escalofríos. Problemas pulmonares (neumonitis). IBRANCE puede provocar una inflamación de los pulmones grave o potencialmente fatal durante el tratamiento y puede conducir a la muerte. Informe a su profesional médico de inmediato si tiene algún síntoma nuevo o si sus síntomas empeoran, que incluyen: * dolor de pecho * tos con o sin flema * dificultad para respirar o falta de aire Su médico puede interrumpir o detener por completo el tratamiento con IBRANCE si sus síntomas son intensos. Antes de tomar IBRANCE, informe a su médico todas sus afecciones médicas, incluyendo si: * tiene fiebre, escalofríos o cualquier otro signo o síntoma de infección. * tiene problemas hepáticos o renales. * está embarazada o planea embarazarse; IBRANCE puede hacer daño a su bebé por nacer. * Las mujeres con capacidad de quedar embarazadas deben utilizar un método anticonceptivo eficaz durante el tratamiento y, como mínimo, durante 3 semanas después de tomar la última dosis de IBRANCE. Es posible que su médico le pida someterse a una prueba de embarazo antes de iniciar el tratamiento con IBRANCE. * Los hombres que tengan parejas del sexo femenino que puedan quedar embarazadas deben utilizar un método anticonceptivo eficaz durante el tratamiento con IBRANCE y, como mínimo, durante 3 meses después de tomar la última dosis de IBRANCE. * está amamantando o planea hacerlo. Se desconoce si IBRANCE se excreta en la leche materna. No amamante mientras esté en tratamiento con IBRANCE ni durante 3 semanas después de tomar la última dosis. Los efectos secundarios más frecuentes de IBRANCE incluyen: * Bajos recuentos de glóbulos rojos y bajos recuentos de plaquetas. Llame de inmediato a su médico si presenta cualquiera de estos síntomas durante el tratamiento: * mareos * falta de aliento * debilidad * sangrado o formación de moretones con más facilidad * sangrado nasal * infecciones * cansancio * náuseas * llagas en la boca * anomalías en las pruebas de función hepática * diarrea * afinamiento o caída del cabello * vómitos * sarpullido * pérdida del apetito IBRANCE puede causar problemas de fertilidad en los hombres. Esto puede afectar su capacidad de engendrar un hijo. Si esto le preocupa, antes de tomar IBRANCE hable con su proveedor de atención médica sobre sus opciones de planificación familiar. Estos no son todos los posibles efectos secundarios de IBRANCE. Para obtener más información, consulte a su médico. Informe a su médico sobre todos los medicamentos que toma, incluidos los medicamentos de venta con receta y los de venta libre, vitaminas y suplementos a base de hierbas. IBRANCE y otros medicamentos pueden afectarse mutuamente, causando efectos secundarios. No beba jugo de toronja ni coma productos a base de toronja mientras toma IBRANCE, ya que pueden aumentar la cantidad de IBRANCE en la sangre. Informe a su médico si comienza a tomar un nuevo medicamento. Tome IBRANCE exactamente como se lo indique su médico. Si toma una dosis demasiado alta de IBRANCE, llame de inmediato a su médico o acuda a urgencias del hospital más cercano. Le recomendamos que informe los eventos adversos relacionados con los productos de Pfizer llamando al 1-800-438-1985 (EE. UU. únicamente). Si lo prefiere, puede comunicarse directamente con la Administración de Medicamentos y Alimentos de los EE. UU. (Food and Drug Administration, FDA). Visite www.fda.gov/medwatch o llame al 1-800-FDA-1088. (EE. UU. únicamente). INDICACIONES IBRANCE cápsulas y comprimidos de 125 mg son un medicamento de venta con receta que se utiliza en adultos para el tratamiento del cáncer de mama con receptor hormonal positivo (HR+) y receptor 2 del factor de crecimiento epidérmico humano negativo (HER2-) que se ha propagado a otras partes del cuerpo (metastásico) en combinación con: * un inhibidor de la aromatasa como primera terapia hormonal en mujeres posmenopáusicas o en hombres, o bien, * fulvestrant en personas con progresión de la enfermedad después de la terapia hormonal. Consulte la Información Completa de Prescripción y la Información Para el Paciente. Consulte la Información Completa de Prescripción y la Información Para el Paciente. Enable JavaScript to visit this website. Live chat:Chat with an Expert