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ISSN 2771-6309
INTERNATIONAL JOURNAL OF CLINICAL IMAGES AND MEDICAL REVIEWS
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International Journal of Clinical Images and Medical Reviews (ISSN 2771-6309) is
a peer reviewed journal dedicated to publishing clinical images, Case Reports,
Researches, Reviews, Mini Reviews, Short communications etc, from all sectors of
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about new discoveries and treatments in science and medicine and accepts topics
such as surgery, histology and cytology, oncology, dentistry, immunology,
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Finally, in order to preserve the highest quality of the information in this
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PUBMED
INDEXED ARTICLES
Title:Consequences of In utero exposure to synthetic estrogens and progestogens
for children and grandchildren.
Aurthor's :Soyer-Gobillard MO, Gaspari L, Sultan C.
DOI: IJCIMR-V1-0001001.pdf
Title:The incidence and mortality of COVID-19 related TB infection in
Sub-Saharan Africa: A systematic review and meta-analysis.
Aurthor's :Tamuzi J.L., Lulendo G., Mbuesse P.
PDF: IJCIMR-V1-1036.pdf
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INDEXING
LATEST
ARTICLES
ASSESSMENT OF ORGAN MOTION IMPACT ON BRACHYTHERAPY TREATMENT PLANNING OF CERVIX
CANCER
Original Article
Eight consented patients (a total of 12 fractions) undergoing CC brachytherapy
underwent a second paraxial T2-weighted MRI (MRI2) about 2-3 hours after the
initial planning MRI (MRI1) and before treatment delivery. The organs at risk
(OARs) were delineated on MRI1/MRI2. MRI2 and MRI1 were rigidly registered. The
high-risk clinical target volume (HR- CTV), the intermediate risk CTV (IR-CTV),
and the dose map were copied from MRI1 to MRI2.
DOI: 10.55920/IJCIMR.2024.04.001159
EFFECT OF CHIMERISM ON RELAPSE IN STEM CELL TRANSPLANTATION
Original Article
Chimerism guides the clinician about the patient's immune response after stem
cell transplantation.Chimerism is studies in which unique DNA fragments in both
the donor and recipient are used as markers using stem cell pre-transplant DNA
samples.. Post-transplantation, the recipient is evaluated for these uniquely
identifying DNA fragments. In the absence of donor DNA fragments detected in
recipient samples, graft rejection can be considered.ultimately the recipient
DNA frag ments are a proof of the recipient's hematopoiesis.
DOI: 10.55920/IJCIMR.2024.04.001158
THE “CLOT SIGN”, A VALUABLE IMAGING CLUE FOR RADIOLOGISTS AND SURGEONS
Clinical Image
A 28-year-old female presented to the emergency department with acute abdominal
pain in the right iliac fossa. Clinical examination revealed a pale and
tachycardic patient with tenderness in the right iliac fossa. Following an
ultrasound that showed a moderate amount of peritoneal fluid, an abdominal CT
scan was requested, revealing hemoperitoneum with clot sign (Figure 1) and
contrast extravasation in the pelvic region (Figure 2).
DOI: 10.55920/IJCIMR.2024.04.001157
ARTHROSCOPIC REPAIR OF FULL-THICKNESS CARTILAGE DEFECTS IN HORSES WITH
AUTOLOGOUS NASAL CHONDROCYTES SEEDED IN AN INJECTABLE HYDROGEL: FROM PRECLINICAL
DEVELOPMENT TO CLINICAL CASES
Case Report
Articular cartilage is frequently damaged as a result of trauma or degenerative
joint disease, and because it is an avascular and poorly cellularized tissue in
adults, its capacity for spontaneous repair is limited (Hanie et al., 1992;
Hurtig et al., 1988; Vachon et al., 1986). Indeed, only osteochondral defects,
which affect both the subchondral bone and cartilage exhibit a repair process
that leads to the formation of fibrocartilage. This fibrocartilage does not
however display the mechanical properties of native articular cartilage
(Buckwalter and Mankin, 1998) and unfortunately degrades rapidly.
DOI: 10.55920/IJCIMR.2023.04.001156
RECURRENT CUTANEOUS MYOEPITHELIOMA OF THE SCALP CASE REPORT: MANAGEMENT AND
HISTOLOGICAL ANALYSIS.
Case Report
Myoepithelial cell neoplasms consists of an uncommon group of tumors. These may
be both malignant and benign. Even if rare there is a quite proper
characterization. Actually, the best known is the salivary gland myoepithelioma,
but recently extra salivary examples have been reported (1). In this clinical
case, a cutaneous location of myoepithelioma (CM) is described. This is an even
more under-recognized tumor that generally behaves in a benign fashion.
DOI: 10.55920/IJCIMR.2023.04.001154
ROLE OF ULTRASONOGRAPHY IN PERIPHERAL NERVE INVOLVEMENT IN LEPROSY: A
CROSS-SECTIONAL STUDY
Research Article
Leprosy is a chronic infectious disease caused by Mycobacterium leprae (M.
leprae). Two key components of the disease are skin and nerve involvement.
Leprosy patients develop anaesthesia of hands and feet, which puts them at risk
of developing deformity and contractures.(7) Loss of fingers and toes is caused
by repeated injury in weak, anaesthetic limbs, and these visible deformities
cause significant stigmatisation. Mononeuritis multiplexis a typical
presentation of leprosy. (8) Diagnosis is based on the recognition of anesthetic
skin lesions, identification of enlarged nerves, and the demonstration of the
causative organism M leprae.
DOI: 10.55920/IJCIMR.2023.04.001153
ULTRASOUND FINDING OF SUBCLINICAL JOINT AND TENDON INFLAMMATION OF THE PATIENTS
WITH SYSTEMIC LUPUS ERYTHEMATOSUS
Case Report
According to clinical manifestations, systemic lupus erythematosus (SLE) can be
classified as a mild, moderate, or severe disease, which is significant for
treatment selection. Musculoskeletal manifestations are considered mild, but in
practice, they can often persist, relapse, and be resistant to treatment,
requiring the use of multiple therapy modalities and potent immunosuppressants.
Musculoskeletal manifestations occur in approximately 95% of patients, with
around 50% experiencing them as the initial presenting symptom [1,2]. These
manifestations can be symptomatic (clinically recognizable) or asymptomatic,
causing significant disability and socio-economic consequences [3].
DOI: 10.55920/IJCIMR.2023.04.001152
METASTASIS OF HEPATOCELLULAR CARCINOMA IN THE ORBIT AS FIRST MANIFESTATION OF
EXTRAHEPATIC SPREAD- A CASE REPORT AND REVIEW OF THE LITERATURE
Case Report
Primary liver cancer is one of the most common malignancies globally, being the
sixth cause of cancer and third in cancer-related mortality [1]. Its’ incidence
is expected to rise even further by 2040 [1]. Hepatocellular carcinoma (HCC)
consists of the 75-85% of all primary liver malignant neoplasms. Liver cirrhosis
of any cause is the most important risk factor for HCC development [2].
Extrahepatic metastatic HCC was estimated at 15-50% [3-7] with the most common
sites being the lungs (47-55%), lymph nodes (45-53%), bones (28-37%) and adrenal
glands (11-12%) [8].
DOI: 10.55920/IJCIMR.2023.04.001151
SELECTION OF FFPE BLOCKS WITH CONFOCAL MICROSCOPE TO REDUCE ROUTINE WORKLOAD IN
PATHOL- OGY DEPARTMENT
Original Research
In the current setting of a pathology department, the entire workflow from fresh
specimen to formalin fixed paraffin embedded (FFPE) tissue blocks and HE stained
microscopic slides is resource-intensive due to lack of automation. However,
shortcuts in the workflow may be an interesting introduction prior to a more
complete automation and double us as a resource saving method in a pathology
department. We decided to study such a potential shortcut in workflow by
focusing on the step between paraffin embedding and the production of H&E
stained slides.
DOI: 10.55920/IJCIMR.2023.04.001150
BILATERAL FRONTAL SINUS ECTOPIC ANGIOFIBROMA: FOCUS ON MANAGEMENT OF A RARE
LESION WITH UNUSUAL PRESENTATION.
Case report
Extranasopharyngeal angiofibromas (ENA) involving paranasal sinuses represent an
unusual finding and the localization at the level of frontal sinus is an
extremely rare event with few cases reported inliterature [1,2]. The clinical
presentation is aspecific, lacking the typical features of their more common
nasopharyngeal counterpart with which they share the histological
characteristics.
DOI: 10.55920/IJCIMR.2023.04.001149
RISK FACTORS FOR MORBIDITY AND MORTALITY IN PATIENTS WITH HEMORRHAGE SPONTANEOUS
CEREBRAL
Research Article
Spontaneous cerebral hemorrhage is non-aneurysmal or intracranial hemorrhage not
associated with trauma or other structural injury. It constitutes 10-15% of all
strokes1. Depending on the location, it can be supratentorial or infratentorial.
Its most frequent location is in the basal ganglia, associated with the most
frequent cause, which is uncontrolled arterial hypertension, its incidence
increasing with age2.
DOI: 10.55920/IJCIMR.2023.04.001148
PREVALENCE AND IMPACT OF GASTROESOPHAGEAL REFLUX DISEASE IN INFANTS AND CHILDREN
Review Article
Definition: GER is the passage of gastric content from the stomach to the
esophagus, with or without regurgitation or vomiting.[1] GER is a common chronic
GI disorder. As per [2], It is normal physiologically, typically after meals, it
occurs throughout the day in infants and decreases in frequency in children and
adolescents. It may be asymptomatic or cause mild regurgitation or rarely
vomiting. Regurgitation is caused by passive reflux from the stomach into the
pharynx or oral cavity.
DOI: 10.55920/IJCIMR.2023.04.001145
STUDY ON THE EXPRESSION OF RAD51 IN NON-SMALL CELL LUNG CANCER BASED ON
BIOINFORMATICS
Research Paper
Lung cancer remains the most common cause of cancer and cancer death worldwide
[1]. More than 50% of patients die within the first year of lung cancer
diagnosis, and the 5-year survival rate is less than 20%[2]. According to the
latest survey, there were 787,000 new cases of lung cancer in China, with an
incidence rate of 57.26/100,000 and a death rate of 63,100, respectively, with a
mortality rate of 45.87/100,000. Compared with 2010, the number of new cases
increased by 25.56%[3].
DOI: 10.55920/IJCIMR.2023.04.001144
DURAL TAIL SIGN
Clinical Images
A 74-year-old right-handed male presented with headaches, paroxysmal cervical
pain and gait instability that worsened during exercise walking. Neurological
examination demonstrated proximal right lower extremity weakness. T1-weighted
brain magnetic resonance imaging illustrated a well-delineated 26×23-mm mass
with homogeneous enhancement, located in the right parietal convexity and
associated with extensive edema. The presence of a dural tail (Figure 1, arrows)
suggested the diagnosis of meningioma.
DOI: 10.55920/IJCIMR.2022.04.001140
AN UNCOMMON FINDING OF A PARATHYROID LESION.
Short Communication
A 71- year- old Caucasian woman was admitted for hypercalcemia (3,15 mmol/l),
discovered in the context of peritoneal carcinomatosis of unknown primitive.
Laboratory evaluation revealed a primary hyperparathyroidism with an increased
PTH level (176 pg/ml), whereas PTHrp was not detectable. Cervical
ultrasonography showed a nodular formation of the right superior parathyroid
gland (P4), which was well defined, hypoechoic, surrounded by a bright interface
and located behind the thyroid (figure 1). There were no morphological
abnormalities apparent in the other 3 parathyroid glands.
DOI: 10.55920/IJCIMR.2022.04.001139
LIVER TRANSPLANTATION FOR FAVIPIRAVIR-INDUCED CHOLESTASIS AND ALCOHOL
CONSUMPTION - A CASE REPORT AND LITERATURE REVIEW
Case Report
Clinical data indicate that patients with coronavirus disease 2019 (COVID19)
often had abnormal liver function tests, such as aspartate transferase (AST) and
alanine transferase (ALT) [1]. Acute liver injury is defined based on the upper
limit of normal (ULN) serum concentration of ALT, AST, and total bilirubin as
follows: Increased ALT more than 5-fold ULN or ALP more than 2-fold ULN (in the
absence of bone pathology), or simultaneous increase of ALT ≥3-times ULN and
total bilirubin concentration more than 2-times ULN [2].
DOI: 10.55920/IJCIMR.2023.04.001137
REVERSAL OF ACUTE LIVER FAILURE DUE TO WILSON’S DISEASE IN AN ADULT WITHOUT
LIVER TRANSPLANT: ROLE OF INTRAVENOUS ALBUMIN AND PLASMAPHERESIS
Case Report
Wilson’s Disease (WD) is a recessively inherited autosomal disease related to
mutations in the ATP7B gene caused by the accumulation of excess copper in the
body, particularly in the liver, brain, and kidney. It especially affects
children and young adults, but it can occur before three and after 40 years of
age1. The clinical profile of hepatic manifestations may vary from asymptomatic
biochemical abnormalities and steatosis to acute hepatitis, acute liver failure,
chronic hepatitis, and cirrhosis.
DOI: 10.55920/IJCIMR.2023.04.001136
A CASE OF AUTOIMMUNE HYPOPHYSITIS INDUCED BY IPILIMUMAB/NIVOLUMAB COMBINATION
THERAPY FOR METASTATIC MELANOMA
Case Report
An 83-year-old Chinese gentleman presented to the Accident and Emergency
department in July 2021 for severe non-vertigo dizziness and fatigue. He is an
ex-smoker and ex-drinker, with a past medical history of pulmonary tuberculosis
in 2009. 10 months prior to presentation, in September 2020, he was diagnosed
with BRAF-negative metastatic melanoma of scrotum with groin and external iliac
lymph node metastasis.
DOI: 10.55920/IJCIMR.2023.04.001135
STUDENT AND TEACHER SATISFACTION WITH ONLINE MODE OF POSTGRADUATE EXAMINATION
Research Article
In the COVID- 19 era, learning organizations cannot lag in the use of new
technologies[1]. Higher Education Institutions all over the world are
increasingly adopting and implementing online modes.[2,3] Many institutions in
developing countries are facing challenges with online examinations due to a
lack of sensitization of students to online mode and lack of preparation of
students, and lack of internet facilities in some areas.[4] In India, a
nationwide lockdown was implemented due to the coronavirus disease (COVID-19)
pandemic towards the end of March 2020 leading to immense disruption of routine
hospital services and residency training.
DOI: 10.55920/IJCIMR.2023.04.001134
A CHALLENGING CASE OF UNSUCCESSFUL PERCUTANEOUS NEPHROSTOMY TUBE REPLACEMENT FOR
MANAGEMENT OF XANTHOGRANULOMATOUS PYELONEPHRITIS
Clinical Image
A 62-year-old female initially presented in septic shock with altered mental
status and was found to have left renal xanthogranulomatous pyelonephritis (XGP)
on CT scan of the C/A/P (characteristic image in Figure 1). She had percutaneous
nephrostomy tube (PCN) placement for management in addition to antibiotics and
supportive care. She was subsequently discharged on culture-directed oral
antibiotics with PCN to drainage and plan for interval simple nephrectomy of
minimally functional XGP kidney.
DOI: 10.55920/IJCIMR.2023.04.001133
PERCUTANEOUS LIGAMENTUM FLAVUM CYST RUPTURE BY INTERLAMINAR EPIDURAL APPROACH -
A CASE REPORT AND LITERATURE REVIEW
Case report
A ligamentum flavum cyst (LFC) was first reported by Moiel et al. in 1967 [1].
It represents a rare cause of lumbar nerve root compression or spinal stenosis.
LFC is a juxtafacet cyst (JFC), which was reported in 1974 to describe synovial
and ganglion cysts that are adjacent to the facet joints [2]. A previous study
evaluated cystic origins intraoperatively in 58 cases and suggested that JFCs
may originate from three anatomic structures and present as facet cysts, flavum
cysts, and posterior longitudinal ligament (PLL) cysts [3]. The cyst causes back
pain and lower leg pain. The treatment of choice is surgical intervention, and
conservative treatment is also one of the treatments.
DOI: 10.55920/IJCIMR.2022.03.001132
PACHYDERMOPERIOSTOSIS (TOURAINE–SOLENTE–GOLE SYNDROME) IMITATING ACROMEGALY
Review Article
PDP is the primary form of hypertrophic osteoarthropathy (HOA) which should be
distinguished from the secondary form of HOA, which is much more frequent and
mostly associated with severe pulmonary disease, bronchogenic carcinoma, lung
empyema, bronchiectasis, congenital heart disease, and thyroid or GI malignancy
1. It was first described by Friedreich2 in 1868, who called it ‘Hyperostosis of
the entire skeleton’. In 1907, Unna named the term ‘cutis verticis gyrate’ for
thick, transversely folded skin of scalp and forehead.
DOI: 10.55920/IJCIMR.2022.03.001131
INDICATORS OF DAILY MONITORING OF BLOOD PRESSURE AND TROPHOBLAST FUNCTION IN THE
DIFFERENTIAL DIAGNOSIS OF HYPERTENSION IN PREGNANT WOMEN AND PRE-ECLAMPSIA
Review Article
Preeclampsia, remaining one of the most frequent and dangerous complications of
pregnancy and childbirth for many years, is one of the main causes of maternal
perinatal morbidity and mortality[4]. In Russia, despite the decline in the
absolute number of births observed in the last decade, the frequency of
preeclampsia increases from year to year, reaching 16-21%[1]. In recent years,
the frequency of combined preeclampsia has increased (about 70%) [ 2].
DOI: 10.55920/IJCIMR.2022.03.001130
SCORPION STING INDUCED MYOCARDITIS, HYPERPYREXIA AND CONVULSION: - A CASE REPORT
Case report
Scorpion envenomation is a public health problem, common in certain areas of the
world including Middle East, Latin America, Asia and Africa. In tropical and
sub-tropical regions, scorpion stings are considered one of the most important
health challenges. (4) In 2018, WHO reported that the truth of scorpion sting
envenoming is not known because many cases do not seek medical attention and
envenoming accidents occur in villages of tropical and subtropical countries, it
has been estimated that there are approximately 1.23 million stings per year.
(9) Scientists are very keen on treating, reporting and studying the snake bite
than scorpion envenoming. (4, 7) Scorpion sting is ignored because of unknown
prevalence and high number of low income countries.
DOI: 10.55920/IJCIMR.2022.03.001129
STRESS, RESILIENCE, AND SELF-EFFICACY AMONG UNIVERSITY/COLLEGE STUDENTS DURING
COVID-19 PANDEMIC
Case report
From the initial phase of covid 19 pandemic ,globally the economical,
psychosocial, occupational and academic domains have been adversely affected
where prevention of spread of disease through lockdowns has further restricted
the general population.in this period of chaos, the daily life activities
especially have been negatively changed where many higher institutions carried
on online learning to ensure effective academic deliverance despite being
inexperienced in this new mode of teaching. UNICEF revealed that 90% of
countries employed broadcast and digital learning during this pandemic [1,2,3],
according to United Nations
DOI: 10.55920/IJCIMR.2022.03.001128
INVESTIGATION OF DEMOGRAPHIC CHARACTERISTICS OF ESSENTIAL HYPERTENSION PATIENTS
ADMITTED TO CUMHURIYET UNIVERSITY HEALTH SERVICES PRACTICE AND RESEARCH HOSPITAL
Case report
Hypertension (HT) is an important health problem that causes many serious events
such as early mortality, decreased quality of life and increased health
expenditures (1). If HT cannot be treated successfully due to the clinical
picture it creates, it causes serious organ damage (2,3). When the demographic
characteristics of hypertensive individuals are examined, it is seen that blood
pressure is affected by factors such as geographical, ethnic and gender (4). It
is recommended that those with a history of diabetes or cardiovascular disease
are among the most risky groups for the development of HT, and that people with
at least one of these diseases should be screened regularly for HT (5).
DOI: 10.55920/IJCIMR.2022.03.001127
POSTPARTUM HEMORRHAGE COMPLICATED BY PAN-HYPOPITUITARISM: SHEEHAN’S SYNDROME;
CASE REPORT, 2022
Case report
Sheehan's syndrome is hypopituitarism due to postpartum ischemic necrosis of the
pituitary gland and was first described in 1937 by Sheehan [1]. It is rare
complication which occurs in 1 out of every 100,000 births globally and is the
most common cause of hypopituitarism in low- or middle-income countries [2, 3].
The prevalence is much high- er in developing countries, as high as 3.1% in
India where more than half of the affected individuals had home deliveries [4].
DOI: 10.55920/IJCIMR.2022.03.001126
EXUBERANT MOLLUSCUM CONTAGIOSUM IN HIV DISEASE
Clinical Image
A 36-year-old female presented with multiple skin-colored nodules around the
eyes associated with difficulty in vision from right eye for five months (Panel
A and B). She also gave history of significant weight loss. There was no history
of high-risk sexual behavior, intravenous drug abuse, or blood transfusion.
Bedside Tzanck smear showed multiple Henderson Peterson bodies. Lab
investigations revealed HIV positive status with a CD4 count of 98 cells/μl. She
was diagnosed as giant molluscum contagiosum (MC) in a HIV positive patient.
DOI: 10.55920/IJCIMR.2022.03.001125
THE DIFFERENT LOCATIONS FOR COLLECTING BLOOD SAMPLE FROM THE HEART OF RED SOKOTO
GOAT- A CLINICAL APPROACH
Review Article
In Nigeria, goats are the most numerous of all types of livestock numbering
about 27.6 million (FOS, 1986). The animals are primarily for meat production.
The Federal Ministry of Agriculture (FMA, 1981) estimated that goats contributed
about 17 per cent (65 000 tonnes) of the total meat supply in Nigeria. Of the
three breeds of goats in Nigeria Red Sokoto is the predominant and the most
widely used and distributed breed in the northern savannah belts of the country
(Ngere et al, 1984).
DOI: 10.55920/IJCIMR.2022.03.001124
MODELING OF HEAT TRANSFER AND HYDRAULIC RESISTANCE OF AN INTENSIFIED TURBU-LENT
FLOW OF LIQUID OR GAS IN PIPES WITH ANNULAR TURBULATORS
Editorial
The problem of reducing the mass and size heat exchangers is urgent. Enhancement
of convective heat transfer processes is a promising means for solving this
problem. At present, different methods of heat transfer enhancement in channels
have been proposed and studied. Heat transfer in tubes at flow of heat-carries
with constant thermal properties in conditions of heat transfer enhancement is
simulated on the basis of a four-layer scheme of turbulent flow. From numer- ous
results of the previous researches it is known, that at the definite depth of
cavities roughness (smaller than 20 thicknesses of a viscous sublayer), i.e. at
regime of a developed roughness, the fixed vortical flow with regular vortexes
is observed
DOI: 10.55920/IJCIMR.2022.03.001123
MEDICATION ADHERENCE: FACT OR FICTIONS?
Editorial
Proper use of medicine or taking medicine in correct order is essential to cure
any disease. According to the WHO, lack of adherence to treatment regimens leads
to major problems among patients, mostly with chronic illnesses. "Right
administration" depends on at least 5 right factors--right patient, right drug,
right time, right dose and right route [1]. "Medicines won't work if you don't
take it right"--This simple fact is not understood by most people in the world,
as a result still more than half of the patients with chronic diseases in the
developed world do not take their medicine correctly-says WHO [2].
DOI: 10.55920/IJCIMR.2022.03.001122
STEATOHEPATITIC VARIANT OF HEPATOCELLULAR CARCINOMA. “WOLF IN A SHEEP’S
CLOTHING” - A CASE REPORT AND REVIEW OF LITERATURE
Case report
HCC is the most common malignant tumour of the liver accounting for 85-90% of
all primary liver cancers.1 HCC shows an increasing incidence worldwide in both
the developed and developing nations.2 It is the fifth most common cancer and
the second most frequent cause of cancer mortality.3 The prevalence of HCC is
high in Asia and Africa when compared to rest of the world.1 Etiological
association with chronic viral hepatitis (HBV and HCV) and ALD (alcoholic liver
disease) are well documented.2 Recently, NAFLD and NASH (non-alcoholic
steatohepatitis) have also been implicated in the development of cirrhosis and
HCC.4 Several co-factors like genetic susceptibility,
DOI: 10.55920/IJCIMR.2022.03.001121
ELEVATED FACTOR VIII CASE REPORT: A COMPLICATING FACTOR FOR ACUTE CORONARY
SYNDROME
Case report
Atherothrombosis is the main cause of coronary syndrome, due to the presence of
classic cardiovascular risk factors. In some patients, other factors can be
responsible for arterial or venous thrombosis. The presence of other
thrombophilic risk factors such as high homocysteine, Factor VIII (FVIII), lupus
anticoagulant and genetic polymorphisms of hemostatic factors (Factor II and
Factor V Leiden) should be suspected as responsible or adjuvant mechanism
(1,2,3). FVIII is an essential cofactor in the coagulation cascade; FVIII
overexpression can trigger thrombotic disorders and complicate acute coronary
syndrome (ACS).
DOI: 10.55920/IJCIMR.2022.03.001120
IS MY PROFESSION A RISK FOR MY LUNGS? - UNUSUAL CASE OF HYPERSENSITIVITY
PNEUMONITIS.
Case report
A 68-year-old male was referred to the pulmonary clinic with progressive
shortness of breath (SOB) for the last six months. The SOB has worsened in the
two months prior to his presentation. His SOB was exertional, especially when he
climbed stairs. He had undergone an extensive workup for cardiac causes, but the
results were negative for such causes. The patient never smoked and reported no
industrial exposure, pets, or pigeons at home. No other exposure history to any
organic or inorganic agents was reported based on a detailed structured
questionnaire.
DOI: 10.55920/IJCIMR.2022.03.001119
HEMIFACIAL MICROSOMIA: CASE SERIES AND OVERVIEW
Case report
A 15 years old female was referred to department of Radio-diagnosis for
cross-sectional Non-contrast CT scan of Face with 3D reconstruction by
department of plastic surgery. Patient has complaints of facial asymmetry with
skin tags in right pre-auricular region since birth (Figure 1 and 2). NCCT with
3D reconstruction reveals small sized right mandibular ramus, and both right
condylar and coronoid process however condylar process articulating with glenoid
fossa with reduced right temporomandibular joint as compared to left side
(Figure).
DOI: 10.55920/IJCIMR.2022.03.001118
NUTRITION DURING PREGNANCY IN THE ERITREAN CONTEXT
Review Article
A woman’s nutritional status prior to and during pregnancy influences the baby’s
and her own health. A woman's nutritional status should be assessed
preconceptionally with the goal of optimizing maternal, fetal, and infant
health. Pregnancy-related dietary changes should begin prior to conception, with
appropriate modifications across preg- nancy and during lactation. During
pregnancy, women should eat an extra meal per day (in their second and third
trimester, no extra needed in the first one) as well as reduce physical workload
during the final months of pregnancy in order to gain enough weight. The
recommended intake is adding 0, 340, and 452 kcal/day to the estimated
nonpregnant energy requirements in the first, second, and third trimesters,
respectively
DOI: 10.55920/IJCIMR.2022.03.001117
OUTPATIENT STENTING OF POST SLEEVE GASTRECTOMY LEAKS
BRIEF REPORT
Between January and June 2022, 2 patients, a 34- year-old-man and a 22 year-old-
woman, presented, one month and 4 months respec- tively, following laparoscopic
sleeve gastrectomy, a type II (1) gastric leak documented on CT scan. The 2
patients were directly addressed for endoscopic internal drainage of the leak.
The orifice of the leak was identified under the gastroesophageal junction and
catheterized, under endoscopic guidance by a guidewire, followed by the
introduction of a 7Fr,7 cm plastic pancreatic endoprosthesis (Geenen pancreatic
stent, Cook, Limerick) in the anomalous tract. (Figure 1) Patients were
discharged directly after the procedure. Oral antibiotic was prescribed as well
as early soft oral alimentation.
DOI: 10.55920/IJCIMR.2022.03.001116
FEMALE RUNNER WITH AN ELEVATED TROPONIN
Clinical Image
45-year-old female runner with a past medical history of hypertension presented
to the Emergency Department with sudden onset subster- nal chest pain and
diaphoresis after one of her usual running sessions. EKG showed normal sinus
rhythm with nonspecific T-wave changes. Initial troponin I was 1.16 ng/mL, she
was admitted to the Coronary Care Unit and started on a heparin drip. Her
troponin I peaked at 38 ng/mL. Coronary angiography was performed the following
day which suggested Type II spontaneous coronary artery dissection (SCAD)
involving the obtuse marginal artery.
DOI: 10.55920/IJCIMR.2022.03.001115
ASYMPTOMATIC OSTEOID OSTEOMA IN THE MANDIBLE - A CASE REPORT
Case Report
Osteoid osteoma is defined as benign neoplasm1. It is the third most common
benign bone tumor and account for 10-14% of all benign bone tumors after
enchondroma and non-ossifying fibroma 2. They occur most often in the lower
extremities of the appendicular skeleton (80%) 3. Their occurrence in the
craniofacial skeleton is exceptionally rare 3,4. The lesions are often
symptomatic, and patients seek medical help due to pain. Young adults under 30
years of age are usually affect- ed 2,3.
DOI: 10.55920/IJCIMR.2022.03.001114
PREDICTING OF ENROLLMENT AS A PART OF RISK-BASED MANAGEMENT OF CLINICAL TRIALS
Research Article
An obligatory stage before starting a clinical trial is to conduct a study of
the capabilities of clinical centers to implement the protocol - feasibility
(Kibby M., 2011). The same author talks about the flexibility of the concept of
feasibility from sponsor to sponsor. Poorly conducted feasibility study is a
barrier to patient recruitment (Parke J, 2022) and undergones the study to risk
to be failure. Risks which might be raised during the clinical trial is accepted
by clini- cal trials stakeholders and graduated accordingly (Risk classification
guide, 2022).
DOI: 10.55920/IJCIMR.2022.03.001113
ANTIBACTERIAL ACTIVITY OF DEW AND ACACIA GUM ON BIOFILM FORMING OF PSEUDOMONAS
AERUGINOSA
Research Article
Waterborne and foodborne diseases have emerged as the major public health
concerns across the globe. Food-borne diseases are major health problems both in
developed and developing countries (Abunna et al.2016). Utilization of foods and
water contaminated with certain food and water pathogens such as fungi,
bacteria, and viruses, is con- sidered as a major source of foodborne illness
human. Salmonella spp., Escherichia coli, Klebsiella pneumoniae, Pseudomonas
aeruginosa, Staphylococcus aureus, Shigella spp., and Listeria monocytogenes,
are the most frequently reported foodborne pathogens from different parts of the
world (Hoiby et al.2010 and Hassett et al. 2010).
DOI: 10.55920/IJCIMR.2022.03.001112
TUBERCULOSIS IN PERITONEAL DIALYSIS PATIENTS: A DIAGNOSTIC CHALLENGE.
Original Article
Mycobacterium tuberculosis is a contagious infectious illness caused by a
tuberculosis complex mycobacterium, primarily Mycobacterium tuberculosis or
Koch's bacillus (KB) [1]. It is still a huge public health issue across the
world, particularly in underdeveloped nations [2]. It is commonly seen in people
with CKD. Peritoneal localization, which is generally uncommon, has become a
significant type in peritoneal dialysis patients [3]. Positive diagnosis is
challenging in this popula- tion due to the non-specific clinical presentation
[4].
DOI: 10.55920/IJCIMR.2022.03.001111
PHYSICAL EXAMINATION – A KEY FOR GIANT CELL ARTERITIS EARLY DIAGNOSIS
Clinical Image
A 76-year-old woman presented to our hospital in August 2021 with severe right
sided headache, jaw claudication and recurrent episodes of transient visual
loss, with blurred vision, a floating shadow, and flashing lights, lasting less
than 2 minutes. She reported no previous medical history.
DOI: 10.55920/IJCIMR.2022.03.001110
CUTANEOUS METASTASES OF AMPULLARY ADENOCARCINOMA: CASE REPORT AND LITERATURE
REVIEW
Case Report
A 64-year-old woman known for stage IIA (pT3 pN0 M0) ampullary adenocarcinoma
with pancreatobiliary phenotype, underwent Whipple procedure in September 2014
and received gemcitabine as adjuvant chemotherapy. In July 2018, she developed
systemic recurrence with mediastinal disease and superior vena cava syndrome and
received first-line palliative chemotherapy with cisplatin/5-fluorouracil (5FU),
the best response was stable disease. In October 2020 she presented with a
2-month history of rapidly growing scalp lesions on the occipital and left
parietal region.
DOI: 10.55920/IJCIMR.2022.03.001109
AS PARA NEOPLASTIC SYNDROME OPSOCLONUS MYOCLONUS ATAXIA [OMA]
Case Report
OMA is seen in 1 in 10 lakh people.It is manifested with chaotic move- ments of
eyeballs,Myoclonic jerks and/or Tremor and ataxia both appendicular and
truncal.In the children it is associated with Neu- roblastoma and in adults
50%associated with CA breast or small cell carcinoma of the lung.Anti RI
antibodies are associated in 60 to 70 % of OMA associated with CA breast. These
are the antibodies targetted against Nova 1 and Nova 2[1].
DOI: 10.55920/IJCIMR.2022.03.001108
ROLE OF GENERAL PRACTITIONERS NOVEL CORONAVIRUS PNEUMONIA IN PREVENTION AND
CONTROL OF EPIDEMIC SITUATION
Review Article
Novel coronavirus pneumonia has been found in Wuhan, Hubei since the end of
December 2019, and has gradually spread through- out the country. In order to
control the new epidemic situation, the country launched a major public health
level 1 emergency response, implemented nationwide traffic control and travel
restrictions, and required the masses to be isolated at home and spread the way
to re- duce the chance of infection; general practitioners, as the “gatekeep-
er” of community health, gave full play to their continuous man- agement and
service of patients in community places during the epidemic period.
DOI: 10.55920/IJCIMR.2022.03.001107
POINT-OF-CARE ULTRASOUND IN THE DIAGNOSIS AND MANAGEMENT OF CHLAMYDIA-ASSOCIATED
REACTIVE ARTHRITIS WITH ISOLATED PERONEAL TENOSYNOVITIS
Clinical Image
Chlamydia reactive arthritis most commonly presents as an asym- metric
oligoarthritis with lower extremity predominance1. It can have a poor prognosis
due to reinfection, variable clinical manifestations, and overlap with other
common inflammatory arthropathies. Al- though magnetic resonance imaging (MRI)
is often used to evaluate joint effusions, the average wait times have exceeded
two to four weeks with costs ranging between $300-$5,000 dollars2. Point-of-care
ultra- sound (POCUS) can be used as an efficient diagnostic resource while
navigating through the list of differential diagnoses3.
DOI: 10.55920/IJCIMR.2022.03.001106
URINARY INCONTINENCE AFTER RETAINED LUMBAR DRAINAGE CATHETER: A CASE STUDY
Case Study
Lumbar external drainage (LED) is one of the most frequently used salvage
methods in neurosurgery. This method helps to prevent CSF fistula in patients
with risk of developing rhi- norrhea. This report describes a case of a mechanic
complication due to the lumbar drainage system. A 54-year-old woman presented to
the otolaryngology clinic with a complaint of nasal congestion. Radiological
imaging revealed meningocele. During the endoscopic meningocele repair performed
by otolaryngology clinic, cerebrospi- nal fluid leak was observed. Following the
repair of the meningo- cele sac, a LED was inserted into the patient’s lumbar
subarachnoid space to prevent cerebrospinal fluid fistula.
DOI: 10.55920/IJCIMR.2022.03.001105
CA SUCCESS STORY OF A WOMAN MEDICAL PHYSICIST IN THE MIDDLE EAST
Opinion
Most of us pictures the Middle East as a region having conservative culture
where women are considered second class citizens and men dominates the
professionals in whatever field it may be. Not to men- tion the common
misconception elsewhere that women are oppressed in this part of the world, many
of us thinks that middle eastern women have a very limited opportunity when it
comes to professional career and they are thought to be better off staying at
home taking care of the household.
DOI: 10.55920/IJCIMR.2022.03.001104
EOSINOPHILIA AFTER EXPOSURE TO DARBEPOETIN ALFA: A CASE REPORT
Case report
Darbepoetin alfa stimulates erythropoiesis in manner similar to re- combinant
human erythropoietin (rEPO). It differs from rEPO as there are two additional
oligosaccharide chains in darbepoetin alfa.1 These two chains increase the
number of sialic acid residues within the molecule, thereby enhancing its
half-life three-fold compared to rEPO.1 U.S. Food and Drug Administration label
for Darbepoetin alfa indicates that allergic rash and erythema can occurred in
5% of patients taking darbepoetin alfa,2 which may be due to the immuno- genic
nature of darbepoetin alfa owing to different amino acid and oligosaccharide
chain sequences (compared to endogenous EPO and rEPO).
DOI: 10.55920/IJCIMR.2022.03.001103
A NEW STRATEGY TO BUILD CULTURE OF COMPASSION IN NURSING PRACTICE
Review Article
Values are generally defined as beliefs or principles that influence behaviour.
Following several reports that revealed poor care quality with an apparent lack
of compassion, England's Department of Health (DH) introduced the ‘6Cs’ as
values for practice within a new nursing strategy. In 2016, the 6Cs were
included in the new framework for nursing (1). This article sets out the
background to the 6Cs, considers other sets of values relevant to nursing
practice and theories of caring, and then explores the meaning of the DH’s 6Cs
in detail.
DOI: 10.55920/IJCIMR.2022.03.001102
CIUS AS A MEASURE OF COMMUNICATIVE PERFORMANCE IN A PERSIAN SPEAKER WITH ANOMIC
APHASIA
Case report
Aphasia is an acquired neurological language disorder, primarily due to brain
injury caused by stroke, which affects language comprehen- sion and production.
Anomia is a type of aphasia, which according to American Hearing and Speech
Association (ASHA) is defined as a mild form of aphasia with word-finding
difficulty being the main characteristic. Individuals with anomic aphasia have
relatively pre- served speech fluency, repetition, comprehension, and
grammatical speech but sometimes have difficulty with word retrieval (Dronkers &
Baldo, 2010)
DOI: 10.55920/IJCIMR.2022.03.001101
INCIDENTAL FINDING OF LUMBAR RIB
Clinical Image
An incidental finding of “thirteenth” or “lumbar” rib was discovered upon
radiological imaging. An oblique radiograph shows the costo- vertebral
articulation (Figure 1., white arrow) between the first lumbar vertebra and the
rib. Axial CT also demonstrates the articulation as well (Figure 2., white
arrow). Three-dimensional volume rendered CT provides a clear view of the bony
architecture of the spine (Figures 3 and 4).
DOI: 10.55920/IJCIMR.2022.02.001100
PYRIMIDINE METABOLISM-RELATED GENE RRM2 AS A NOVEL BIOMARKER FOR PROGNOSIS AND
IMMU- NOTHERAPY IN LUAD
Research Article
Lung adenocarcinoma (LUAD), which accounts for 40% of lung can- cers, is usually
diagnosed at an advanced stage and has a low aver- age 5-year survival rate
(about 20%) [1] [2] [3]. To promote tumor growth, tumor cells initiate a unique
metabolic program [4] [5]. This is not only conducive to the unlimited
proliferation of tumor cells, but also shapes a unique immune microenvironment,
affecting the com- position and biological functions of immune cells in the
microenvi- ronment [6] [7].
DOI: 10.55920/IJCIMR.2022.02.001097
TOTAL KNEE ARTHROPLASTY: SOCIOECONOMIC DISPARITIES OF POST-OPERATIVE
COMPLICATIONS
Research Article
A 2018 American Academy of Orthopedic Surgeons report predicts that TKA rates
will increase by 189% in 2030 and by 382% in 2060.2 Current projections are that
by 2030, there will be 935,000 primary TKAs annually.1 Healthcare disparities
continue to be a concern for total knee arthroplasties (TKAs), and given the
anticipated increase of TKAs, these disparities need to be addressed. Elderly
patients un- dergoing TKA, such as the Medicare beneficiaries analyzed in this
study, have an increased perioperative risk and require close interdis-
ciplinary cooperation for success. For these patients, post-operative function
depends significantly upon psychosocial factors in addition to a patient’s
preoperative health status.
DOI: 10.55920/IJCIMR.2022.02.001096
PREVALENCEOF SACROILIAC JOINT DYSFUNCTION IN PATIENTS WITH LUMBAR DISC HER-
NIATION
Research Article
In individuals with low back pain, sacroiliac joint (SIJ) is the most common
pain causing joint (1). SIJ is developed by the junction be- tween iliac bone
and sacral bone. Association between two bones, muscles and ligaments provide
the stability to the joint. This joint is the largest joint of body with a
diameter of 17.5 cm2 (2). Low back pain approximately affects 80% of the
population. It is extremely com- mon and thus continues to affect millions of
people every year. It is a difficult condition to treat effectively and so it
causes a huge financial burden on the patients as well as the hospitals.
DOI: 10.55920/IJCIMR.2022.02.001095
EVALUATION OF THE RELATIONSHIP BETWEEN THE ADHERENCE TO THE TREATMENTS OF
INDIVIDUALS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND THEIR ATTITUDES
TOWARDS COMPLEMENTARY AND ALTERNATIVE MEDICINE IN THE COVID-19 PANDEMIC
Research Article
Chronic Obstructive Pulmonary Disease (COPD) is one of the im- portant causes of
morbidity and mortality among chronic diseases. Periods of exacerbation seen
during the disease process can cause progression of the disease, increase in
health expenditures and mor- tality (1). The leading cause of COPD exacerbations
is the occurrence of tracheobronchial infections. Viral agents are shown as the
source of tracheobronchial infections (2). All these data; It predicts that in-
dividuals with COPD may be adversely affected by the new type of coronavirus
(COVID-19).
DOI: 10.55920/IJCIMR.2022.02.001094
MONOGENIC SYSTEMIC LUPUS ERYTHEMATOSUS ASSOCIATED WITH DNASE1 GENE MUTATION: A
CASE REPORT AND LITERATURE REVIEW
Research Article
Systemic lupus erythematosus (SLE) in children is an autoimmune disease that can
involve multiple systems, and its pathogenesis is genetically related, with
single mutations causing the disease being extremely rare [1]. No cases of SLE
associated with mutations in the deoxyribonuclease 1 (DNASE1) gene have been
reported in China, and only four cases have been reported abroad [2-3]. One case
of monogenic SLE in a young child associated with DNASE1 mutation was diagnosed
in our hospital through clinical features, autoantibody examination and genetic
testing, and the diagnosis and treatment of this case are reported below.
DOI: 10.55920/IJCIMR.2022.02.001093
A NEW STRATEGY TO BUILD CULTURE OF COMPASSION IN NURSING PRACTICE
Review Article
Values are generally defined as beliefs or principles that influence behaviour.
Following several reports that revealed poor care quality with an apparent lack
of compassion, England's Department of Health (DH) introduced the ‘6Cs’ as
values for practice within a new nursing strategy. In 2016, the 6Cs were
included in the new framework for nursing (1).
DOI: 10.55920/IJCIMR.2022.02.001092
TWO CASE REPORTS OF SUCCESSFUL ENDOVASCULAR TREATMENT OF VERTEBROBASILAR
INSUFFICIENCY: A CASE OF AN INCOMPLETE BALINT SYNDROME AND RECURRENT
VERTEBROBASILAR STROKE
Case Report
High-grade vertebrobasilar insufficiency is an important cause of posterior
circulation stroke. It is characterized by symptoms such as ataxia, diplopia,
hemianopia, cranial nerve palsies and decreased level of consciousness. Among
rare clinical presentations, Balint syndrome consists of the triad of
simultanagnosia, oculomotor apraxia and optic ataxia. It is frequently
associated with bilateral ischemic parieto-occip- ital lesions or some
neurodegenerative diseases.
DOI: 10.55920/IJCIMR.2022.02.001091
A RARE FORM OF URINARY TRACT INFECTION IN A TRANSPLANTED PATIENT
Clinical Image
A 62-years-old woman with end-stage renal disease received a 2nd kid- ney
transplant. The early post-transplant period was complicated with lymphocele
formation, causing bladder and ureteric compression, and left iliac vein
thrombosis. The lymphocele was initially treated with local drainage and
warfarin was also initiated for vein thrombosis. After two months the patient
presented with worsening kidney func- tion and reformation of lymphocele.
DOI: 10.55920/IJCIMR.2022.02.001090
EOSINOPHILIC MYOCARDITIS PRESENTING WITH PROGRESSIVE CARDIAC CACHEXIA
Case Report
Hypereosinophilic syndrome (HES) is a rare hematologic disorder characterized by
persistent overproduction of eosinophils causing multiple organ damage (1).
Cardiac involvement in HES is frequent, found in approximately 50% of patients
with HES, and is associated with high morbidity and mortality rates (2-4). It is
caused by eosino- phil infiltration of the endomyocardium with subsequent tissue
dam- age and endomyocardial fibrosis (5).
DOI: 10.55920/IJCIMR.2022.02.001089
BLUE NEVUS: A CASE REPORT
Case Report
Oral melanocytic nevi (OMNs) are rare and benign melanocytic tu- mors [2, 5, 7,
11]. Long associated with hamartomas, melanocytic nevi are now considered as
neoplasms [7]. OMNs can be congenital or acquired. They are classified
histologically as junctional, compound, intradermal, combined and blue. This
classification is correlated with the location, morphology of the cells and
their distribution [2,7].
DOI: 10.55920/IJCIMR.2022.02.001088
DIGITAL PHANTOMS FOR EVALUATING THE DOSIMETRIC IMPACT OF MRI GEOMETRIC
INACCURACY IN SBRT PLANNING FOR LIVER CANCER IN THE PRESENCE OF MOTION
Research Article
Recent advances in radiation therapy have placed Stereotactic body radiation
therapy (SBRT) as a superior therapeutic option for the treatment of various
tumors especially in the liver compared to other RT techniques [1 - 5]. SBRT has
shown a sustain improvement of local control rates of tumors that are subject to
motion.
DOI: 10.55920/IJCIMR.2022.02.001087
AN UNUSUAL CAUSE OF PELVIC PAIN: GIANT RECTOSIGMOID LITHOBEZOAR IN A BIG CHILD
Clinical Image
We report the case of a rectosigmoid lithobezoar. He was a 10 years old boy,
without any particular history, who was seen in consultation for pelvic pain and
difficulty to defecate. The examination revealed a firm mass in the left iliac
fossa and hypogastrium. On rectal examina- tion, a firm, friable formation with
telluric debris on the glove was found.
DOI: 10.55920/IJCIMR.2022.02.001086
PERSPECTIVES OF JAUNDICE AND IMPLICATIONS
Mini Review
Jaundice involves yellowing of the skin, whites of the eyes, and body fluids. It
is as a result of high level of bilirubin in the blood [1]. The bilirubin simply
is a yellow pigment that is generated from haem me- tabolism, mainly from
haemoglobin in red blood cells (RBCs). This bilirubin is moved by the blood to
the liver, where it is linked with a sugar by an enzyme through conjugation so
that it can be excreted in bile, which later reach the small intestine. It has
been reported that jaundice may result from a problem at any point in the
pathway es- pecially increased breakdown of RBC, liver dysfunction or problems
with excretion of bile [2].
DOI: 10.55920/IJCIMR.2022.02.001085
DIFFUSE BILIARY PAPILLOMATOSIS (IPNB) ASSOCIATED WITH IPNM : A CASE REPORT
Case Report
Biliary papillomatosis is a rare event. It concerns the biliary epithelium. The
definition of the World Health Organization is the presence of multifocal
papillary lesions on intra hepatic and/or extrahepatic bile ducts 1. There is a
risk of malignant transformation. The papillary lesions are producing mucus
conducting to biliary obstruction. Right hypochondrium pain and jaundice are the
more frequent symptoms.
DOI: 10.55920/IJCIMR.2022.02.001083
EVALUATION OF PREDICTIVE FACTORS ASSOCIATED WITH PROGNOSIS OF PATIENTS WITH
SOLITARY HEPATOCELLULAR CARCINOMA RECEIVING TRANSCATHETER ARTERIAL
CHEMOEMBOLIZATION
Original article
Hepatocellular carcinoma (HCC) occurs most often in underlying chronic liver
diseases including advanced fibrosis or cirrhosis, which is usually related to
chronic hepatitis B virus (HBV), hepatitis C virus (HCV) infection, prolonged
alcohol use, or nonalcoholic fatty liver disease.1.2 The Barcelona Clinic Liver
Cancer (BCLC) staging system can be used to assess therapeutic options,3 such as
transcatheter arterial chemoembolization (TACE), which is recommended as the
treatment modality for intermediate stage, or BCLC stage B, HCC.
DOI: 10.55920/IJCIMR.2022.02.001082
NEGATIVE PRESSURE WOUND THERAPY FOR NECROTIZING FASCIITIS OF THE HEAD AND NECK:
A CASE REPORT
Case Report
Necrotizing fasciitis (NF) is an acute severe infection of the superficial
fascia that rapidly progresses, causing fascial necrosis with serious damage to
the surrounding skin, subcutaneous tissue, muscle, and soft tissue. It can be
caused by polymicrobial bacteria including mixed aerobic and anaerobic species.
The incidence rate of NF is approximately 3.5–4 cases per 100,000 people. Among
them, cervical NF accounts for only approximately 5%.
DOI: 10.55920/IJCIMR.2022.02.001081
MALIGNANT MASQUERADE – PROXIMAL TO THE HILUM
Case Report
Cholangiocarcinoma is an aggressive malignancy and a challenging disease to
treat, with available literature emphasizing on surgical resection, newer
imaging modalities, adjuvant therapy, and palliative therapy, but just
establishing a tissue diagnosis itself is the most complex problem before
treating such tumors especially in proximally located hilar biliary stricture.
DOI: 10.55920/IJCIMR.2022.02.001080
PANCREATICOPLEURAL FISTULA: REVISITING A RARE COMPLICATION
Case Report
Pancreatic fistula is a rare complication of acute pancreatitis, chronic
pancreatitis and pancreatic trauma. It develops because of pancreatic ductal
disruption or rupture of a pseudocyst. Pancreatic ascites develops due to free
secretion of pancreatic juice into peritoneal cavity . Its challenging to
diagnose this rare complication and even more challenging to treat it adequately
. Left pleura is the most common location for pancreatic fistula followed by
right pleura and both pleural cavities.
DOI: 10.55920/IJCIMR.2022.02.001079
GUT MICROBIOTA AND INTESTINAL IMMUNE SYSTEMS -IMMUNE CONTROL FUNCTIONS VIA
SHORT-CHAIN FATTY ACIDS, AMINO ACID METABOLITES AND BILE ACIDS
Mini Review
Intestinal environments, including gut microbiota, are deeply involved in the
developments and control of intestinal immune systems. Gut microbiota exerts
various actions on immune cells through bacterial cell components and
metabolites produced by the bacteria.
DOI: 10.55920/IJCIMR.2022.02.001078
ACUTE KIDNEY INJURY AND COVID-19 INFECTION
Review Article
Coronavirus disease (COVID-19) is an infection that has been one of the most
frequently discussed medical as a socio-economic issues over the past two years.
Common risk factors for COVID-19 infection and its severe course include age,
race, male gender, chronic lung disease, cardiovascular disease (CVD), diabetes
mellitus (DM), immunode- ficiency, kidney and liver disease, obesity/overweight,
smoking and polypharmacy.
DOI: 10.55920/IJCIMR.2022.02.001077
TO DETERMINE SENSITIVITY OF DIFFUSION WEIGHTED IMAGING FOR DIAGNOSIS OF
HEPATOCELLULAR CAR- CINOMA, KEEPING THE DYNAMIC POST CONTRAST MRI AS GOLD
STANDARD.
Research Article
There is increasing incidence of hepatocellular carcinoma (HCC) worldwide, being
the fifth commonest cancer and holds being the sec- ond commonest reason of
cancer death [1]. It is alarmingly on rise in Pakistan [2, 3]. Multiple risk
factors for HCC have been documented worldwide, a few include alcohol, hepatitis
B and C viral infection and non-alcoholic fatty liver disease (NAFLD). With
current disease load it is crucial to accurately diagnose HCC at the early stage
for reduc- ing the morbidity and mortality. Early diagnosis is the rate limiting
step in the disease burden.
DOI: 10.55920/IJCIMR.2022.02.001076
THE USING OF BIPHASIC CALCIUM SULFATE IN TWO-STAGE TREATMENT OF ODONTOGENIC
FIBROMA OF THE MANDIBLE – CASE REPORT
Case Report
Among the patients of the Oral Surgery Department, a significant per- centage
are people requiring treatment due to the diagnosis of odon- togenic cysts in
the jaw bones. Most of these cysts, of various etiolo- gies, require surgical
treatment. The most common lesions of various origins include the germinal cyst,
while the broadly understood root cyst, as a chronic inflammatory pathological
condition, may constitute the highest percentage of recognizable lesions of this
type in the jaw bones. Statistically, it is over 60% of odontogenic cysts and
over 50% of bone cysts[1,2].
DOI: 10.55920/IJCIMR.2022.02.001075
DIETARY MINERAL IMBALANCE AMONG PRIMARY SCHOOL CHILDREN IN BENGHAZI
Research Article
Childhood is the entire blueprint of an individual's future life, evi- dences
show that experiences in early and middle childhood are extremely important for
a child’s healthy development and lifelong learning. How a child develops during
this time affects future cog- nitive, social, emotional, language, and physical
development, which in turn influences school readiness and later success in life
1-3
DOI: 10.55920/IJCIMR.2022.02.001074
CHRONIC GI BLEEDING AS THE ONLY PRESENTING SIGN OF AML IN AN ELDERLY PATIENT
Case Report
While acute myeloid leukemia (AML) remains a common type of leukemia in adults,
it is a relatively rare cancer diagnosis overall, re- sponsible for only one
percent of adult cancer deaths in the United States.1-3 AML stems from the
malignant clonal expansion of undif- ferentiated myeloid precursor cells,
resulting in ineffective hematopoi- esis and bone marrow failure.1,2 The
production of malfunctioning white blood cells can cause cytopenia’s, creating
downstream symp- toms related to anemia and thrombocytopenia.1-4 However, a
handful of individuals may be asymptomatic upon diagnosis with isolated lab
abnormalities.
DOI: 10.55920/IJCIMR.2022.02.001073
SPONTANEOUS REGRESSION OF ELTROMBOPAG INDUCED BONE MARROW FIBROSIS, IN A PATIENT
WITH CHRONIC IMMUNE THROMBOCYTOPENIA
Case Report
Immune thrombocytopenia (ITP) is an autoimmune bleeding disor- der that lessens
the production of platelets. ITP is a syndrome char- acterized by: (i)
thrombocytopenia (platelet count less than 100,000/ mm3); (ii) shortened
platelet survival; (iii) presence of antiplatelet an- tibody in the plasma; (iv)
normal or increased megakaryocytes in the bone marrow [1]. Patients are over 60
years of age with no predilection for sex and the chronic form being the most
common.
DOI: 10.55920/IJCIMR.2022.02.001072
POSTPARTUM DEPRESSION: A COMPREHENSIVE REVIEW
Review Article
Postpartum depression is a form of depression, a mental illness, dis- covered to
be common lately in birth mothers affecting roughly 15% to a minimum of 10%.
Such a period is very critical due to its nature and effect on Mother-baby
bonding and Child’s long-term Devel- opment. However, following depressions are
found to be very inad- equately diagnosed and nursed. According to the survey
carried out in this regard revealed that halves of such conditions are
unidentified by concerned Practitioners or medical Professionals in-charge and
revealed that most of the diagnosed mothers, do not follow recom- mended
treatment accordingly.
DOI: 10.55920/IJCIMR.2022.02.001071
PREVALENCE OF CERVICAL EPITHELIAL CELL DYSFUNCTION IN PAPANICOLAOU SMEARS
REPORTS IN LOW-RISK POPULATION REFERRED TO IMAM REZA HOSPITAL
Original Article
Cervical cancer is one of the most preventable malignancies among human cancers.
Infection of the uterine cervix with human papilloma- virus (HPV) is the main
causative agent of cervical cancer [1]. About 15 high-risk types of human
papilloma virus have been identified, which are responsible for cervical
neoplasia and other related cancers [2]. Cervical cancer with worldwide
distribution, though a prevent- able disease, is one of the leading causes of
cancer death in women.
DOI: 10.55920/IJCIMR.2022.02.001070
THE EFFECT OF GESTATIONAL DIABETES ON THE Α7 AND Α4 SUBTYPES OF NACHRS IN HUMAN
PLACENTA
Original Article
Gestational diabetes mellitus (GDM) is developed among those preg- nant women
with inadequate pancreas function that cannot overcome resistance to insulin
[1]. GDM increases blood glucose level that can be initiated or diagnosed for
the first time in pregnancy. It was esti- mated that diabetes affects up to 15 %
of pregnant women worldwide [2]. Moreover, its prevalence is increasing in all
parts of the world [3].
DOI: 10.55920/IJCIMR.2022.02.001069
MYOCARDIAL INFARCTION FOLLOWING COVID-19 VACCINATION
Short Communications
The rapidly spreading COVID-19 virus has killed millions(1). Vac- cination is
the best way to prevent severe illness and death(2). Local reactions at the
injection site and nonspecific systemic effects (myal- gia, chills, fatigue,
headache, and fever) are common side effects of this vaccine(3).
DOI: 10.55920/IJCIMR.2022.02.001068
MAIN LEFT CORONARY PRINZMETAL ANGINA: A RARE CAUSE OF ACUTE MYOCARDIAL IN-
FARCTION AND DILATED CARDIOMYOPATHY.
Case Report
Prinzmetal's Angina is a rare cause of chest pain. It occurs when a cor- onary
artery goes into spasm, usually among young patients leading to angina pectoris
with electrocardiographic changes. 1The spasm can be focal or diffuse and affect
the epicardial or microvascular coronary arteries, in addition there is a risk
of sudden death, acute coronary syndrome, syncope and arrhythmias.
DOI: 10.55920/IJCIMR.2022.02.001067
CLINICOPATHOLOGICAL ANALYSIS OF 20 CASES OF SUBCUTANEOUS SARCOIDOSIS IN SOUTH
KOREA
Research Article
Sarcoidosis is a multisystem granulomatous disorder of unclear ori- gin.1 The
diagnosis of sarcoidosisis well established when clinical and radiological
findings are supported by histological evidence of non- caseating granulomas in
one or more tissues.2 It involves mainly the lungs, mediastinal and peripheral
lymph nodes, skin, liver, spleen, eyes and parotid glands.
DOI: 10.55920/IJCIMR.2022.02.001066
EFFECTS OF ETHNICITY ON ALLOGENIC STEM CELL MOBILIZATION
Original Article
Allogeneic stem cell transplant (ASCT) is a treatment method for var- ious
malignant and non-malignant hematologic disorders. The plu- ripotent
hematopoietic stem cells are usually obtained from the bone marrow or peripheral
blood of a donor. The results of allogeneic bone marrow transplantation from the
human leukocyte antigen (HLA) compatible sibling are much better.
DOI: 10.55920/IJCIMR.2022.02.001065
PAEDIATRIC CUTANEOUS MASTOCYTOSIS : REPORT OF 3 CASES
Case Report
Mastocytosis is characterized by an abnormal mast cell infiltrates. It can occur
at any age. Severity of this disease ranges from fleetingly benign to
aggressively malignant contitions. Cutaneous mastocytosis is most common in
children. About 50% of affected children develop typical skin lesions before the
age of 6 months.
DOI: 10.55920/IJCIMR.2022.02.001064
SICKLE CELL DISEASE AND PROJECTION INTO FUTURE IN AFRICAN PATIENTS LIVING IN
FRANCE, BORN IN AFRICA AND THOSE BORN IN FRANCE FROM AFRICAN PARENTS
Research Article
Sickle cell disease (SCD) is a serious chronic disease that manifests itself
from early childhood with intense pain, chronic anemia, infec- tions to which
can be added acute and chronic complications affecting the brain, heart, lungs,
and kidneys, among others. All organs can be affected. A genetic disease, it is
transmitted to the child by both par- ents, each carrying the S gene for sickle
cell disease.
DOI: 10.55920/IJCIMR.2022.02.001063
A TECHNIQUE FOR PROSTHETICALLY ALIGNING MULTIPLE NON-PARALLEL IMPLANTS
Technique
Placing implants in a proper prosthetic position and direction is es- sential to
achieve a successful long-lasting restoration.1 However, this is sometimes
difficult to achieve because of anatomical or technical difficulties and angled
abutments are required to correct the unfavor- able alignment.
DOI: 10.55920/IJCIMR.2022.02.001062
IMPORTANCE OF MAINTAINING AND IMPROVING IMMUNE FUNCTION BY PHYSICAL ACTIVITY
DURING THE COVID-19 PANDEMIC
Mini Review
In early December 2019, a novel coronavirus disease, designated as COVID-19,
came into light in Wuhan, Hubei Province of China. With the first pneumonia
cases of unknown origin being identified, it has be- come a pandemic worldwide.
The World Health Organization (WHO) has declared it as a potential threat to the
world population, and a pub- lic health emergency of international concern on
January 30, 2020.
DOI: 10.55920/IJCIMR.2022.02.001061
COMBINED CERVICAL LACERATION AND BLADDER RUPTURE: A CASE REPORT OF AN UNUSUAL
COMPLICA- TION OF PRECIPITATED LABOR
Case Report
Spontaneous bladder rupture following normal vaginal delivery is a surgical
postpartum emergency. Previous cesarean section, vacuum/ forceps-assisted
vaginal deliveries, and distended bladder compressed by engaged head in birth
canal are all risk factors for bladder injuries in healthy parturient women 1.
DOI: 10.55920/IJCIMR.2022.02.001060
RESEARCH PROGRESS OF RHUBARB IN THE TREATMENT OF LIVER FIBROSIS
Review Article
Liver fibrosis is the excessive accumulation of extracellular matrix proteins
including collagen that occurs in most types of chronic liver diseases.It is a
complex disease centered on the activation of hepatic stellate cells and
regulated by a variety of cell signal transduction pathways.Advanced liver
fibrosis can results in cir - rhosis, liver failure, and portal hypertension.
DOI: 10.55920/IJCIMR.2022.02.001056
UNILATERAL BIPORTAL ENDOSCOPY DISCECTOMY FOR HIGH GRADE MIGRATED LUMBAR DISK
HERNIATION WITH A HOMEMADE GUIDER
Case Presentation
Compared with open lumbar disk herniation discectomy, percutane- ous endoscopic
discectomy(PED)has advantages of smaller incision and faster recovery in the
treatment of lumbar disk herniation. Al- though successful results have been
achieved with the improvement of technology and equipment, the application of
PED to treat high- migrated disc herniation is still technical challenging.
DOI: 10.55920/IJCIMR.2022.02.001055
DEVELOPMENT OF A NOVEL DENTAL THERMAL IMAGING APPLICATION
Research Article
Thermography is a process where a (thermal) camera captures and generates an
image by using infrared radiation, emitted from an ob- ject [1]. The image
provides an opportunity to visibly record invisible (to the human eye) infrared
energy or heat. Thermography is non- invasive, non-contact, user-friendly and a
portable imaging method and has been used in various industrial fields, such as
engineering and construction.
DOI: 10.55920/IJCIMR.2022.02.001054
RETAINED SEVERED RADIAL ARTERIAL CATHETER
Mini Review
The radial artery is the most frequently utilized site for arterial can-
nulation due to accessibility and safety, with approximately 8 million catheters
placed per year in the USA.1 Radial artery cannulation is associated with a
major complication rate of less than 1%. While the most common complication is
temporary occlusion (19%), common complications such as thrombosis.
DOI: 10.55920/IJCIMR.2022.02.001053
VALIDATION OF REGIONAL WALL MOTION ABNORMALITY ASSESSMENT METHODS BASED ON
CORONARY CT- ANGIOGRAPHY WITH LEFT VENTRICULAR FUNCTION REGARDING PREDICTION OF
HEMODYNAMICALLY REL- EVANT STENOSES WITH INSTANTANEOUS WAVE-FREE RATIO
Original Article
Invasive coronary angiography (ICA) is the gold standard for diag- nostic and
treatment of CAD in high-risk patients [1]. Patients with stable angina or
silent ischaemia undergo revascularization therapy when ischaemia or a
hemodynamically relevant stenosis are detected [2]. The DEFINE-FLAIR and
iFR-SWEDEHEART randomized tri- als demonstrated similar outcomes in FFR
(fractional flow reserve) and iwFR (instantaneous wave-free ratio) guided
revascularizations in patients with intermediate-grade stenosis [3, 4].
DOI: 10.55920/IJCIMR.2022.02.001051
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