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JCPSP Open Access Journal of the College of Physicians and Surgeons Pakistan ISSN: 1022-386X (PRINT) ISSN: 1681-7168 (ONLINE) → Submit Your Manuscript 5-Year Impact Factor: 0.9 Volume 34, 12 Issues, 2024 * Home * About JCPSP * Editorial Board * Instructions For Authors * E-PUB Ahead * Guidelines Qualitative Studies * Indexed In * Policies * Archives * Search CLOSE -------------------------------------------------------------------------------- Journal of College of Physicians and Surgeons Pakistan (JCPSP), is an open access, peer reviewed monthly biomedical journal of the country published regularly since 1991. College of Physicians and Surgeons Pakistan is the parent body of this Journal. -------------------------------------------------------------------------------- The College of Physicians and Surgeons of Pakistan (CPSP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide credits to educational activities. CPSP designates '3 AMA PRA Category 1 Credits' for review of the manuscript of an original study. -------------------------------------------------------------------------------- IMPORTANT ANNOUNCEMENT FOR AUTHORS "A companion journal of JCPSP (the official journal of CPSP) has been launched by the name of JCPSP Case Reports. Submission of Case Reports is now open." Please visit https://jcpspcr.pk/. LATEST ARTICLES VOLUME 34 | ISSUE 11 | NOVEMBER 2024 Editorial FROM DISSERTATION TO ORIGINAL PAPER: A JOURNEY TOWARDS QUALITY AND STANDARDS IN RESEARCH By Khalid Masud Gondal Download PDF Read Full Article -------------------------------------------------------------------------------- Original Article IMMUNOMODULATORY POTENTIAL OF MELATONIN IN IMMUNOSUPPRESSION: AN IN-VIVO STUDY By Aamina Quddus Qureshi, Saghir Ahmed Jafri, Ambreen Tauseef, Waqar Ahmed Siddiqui, Amna Irum, Ayela Eman Zia ABSTRACT Objective: To assess the immunomodulatory effects of melatonin on the acquired immunity of immunosuppressed male Wistar rats by checking Interleukin 6 (IL-6) levels, total leucocyte counts (TLC), and differential leucocyte counts. Study Design: Experimental study. Place and Duration of the ... Download PDF Read Full Article -------------------------------------------------------------------------------- Original Article POST-NEUTRALISATION ACTIVATED CLOTTING TIME AND POSTOPERATIVE TRANSFUSIONS IN CARDIAC SURGERY OUTCOME By Muhammad Arslan Zahid, Syed Shabbir Ahmed, Muhammad Saad Yousuf, Sadique Ali Wadho, Muhammad Irfan Akhtar, Mohammad Hamid ABSTRACT Objective: To assess the impact of post-protamine neutralisation activated clotting time (ACT) values on postoperative outcomes including chest drain output, transfusion requirements, and CICU stay, in patients undergoing cardiac surgery. Study Design: Observational comparative study. Place... Download PDF Read Full Article View Graphical Abstract -------------------------------------------------------------------------------- Original Article CLINICAL EFFECTIVENESS OF GREEN TEA EXTRACTS AS A LOCAL HAEMOSTATIC AGENT FOLLOWING MANDIBULAR MOLAR EXTRACTION By Mashail M.M. Hamid, Seham Saleh Al-Amer, Jamilah Dhafer Alahmari, Budoor Ahmed Assiri, Taghreed A. Majrashi, Atiya A. Khan ABSTRACT Objective: To determine the clinical effectiveness of different green tea extracts (GTEs) in reducing bleeding after extraction of mandibular molars. Study Design: Randomised controlled trial. Place and Duration of the Study: College of Dentistry, King Khalid University, Abha, Saudi Arabia,... Download PDF Read Full Article View Graphical Abstract -------------------------------------------------------------------------------- Original Article PROGNOSTIC FACTORS AFFECTING DAY+100 SURVIVAL IN PATIENTS UNDERGOING ALLOGENEIC HAEMATOPOIETIC STEM CELL TRANSPLANTATION FOR ACUTE LEUKAEMIA - A SINGLE CENTRE EXPERIENCE By Awais Siddiq, Mehreen Ali Khan, Jehanzeb Ur Rehman, Yasir Abbas, Hashim Khan, Uzma Rahim ABSTRACT Objective: To determine the factors affecting the first 100 days of survival in acute leukaemia patients undergoing allogeneic haematopoietic stem cell transplantation (Allo-HSCT). Study Design: Descriptive study. Place and Duration of the Study: Bone Marrow Transplant Centre, Rawalpindi, P... Download PDF Read Full Article -------------------------------------------------------------------------------- Original Article IMPACT OF SIMULTANEOUS PRESENCE OF MULTIPLE PML-RARA ISOFORMS ON PHENOTYPE IN PATIENTS WITH ACUTE PROMYELOCYTIC LEUKAEMIA By Emine Goktas, Ayse Gul Zamani, Mahmut Selman Yildirim, Sinan Demircioglu, Atakan Tekinalp, Ozcan Ceneli ABSTRACT Objective: To determine the coexistence of multiple PML-RARA transcripts in adult APL (acute promyelotic leukaemia) patients, and its impact on the patients’ laboratory parameters, treatment responses, and prognoses. Study Design: Cross-sectional study. Place and Duration of t... Download PDF Read Full Article View Graphical Abstract -------------------------------------------------------------------------------- Original Article ASSOCIATION OF VITAMIN D WITH HAEMATOLOGICAL INFLAMMATORY INDICES IN PATIENTS WITH BACK PAIN By Yasemin Ozkan, Mahmut Alpayci, Veysel Delen ABSTRACT Objective: To assess the relationship between vitamin D and haematological inflammatory indices (HII) in chronic low back pain (CLBP) patients. Study Design: Descriptive study. Place and Duration of the Study: Harran University Hospital, Sanliurfa, Turkiye, between September 2023 and Februa... Download PDF Read Full Article View Graphical Abstract -------------------------------------------------------------------------------- Original Article DIAGNOSTIC ACCURACY OF COMBINED MEASUREMENT OF SERUM HOMOCYSTEINE, C-REACTIVE PROTEIN, AND SERUM FERRITIN IN MILD COGNITIVE IMPAIRMENTS AND ALZHEIMER’S DISEASE By Yiyang Li, Lin Duan, Yankui Shi, Ji Qi, Tongtong Li ABSTRACT Objective: Evaluation of the diagnostic accuracy of combined detection of serum homocysteine (Hcy), C-reactive protein (CRP), and serum ferritin (SF) levels in patients with Alzheimer’s disease (AD) and mild cognitive impairment (MCI). Study Design: Descriptive study. Place and Durati... Download PDF Read Full Article View Graphical Abstract -------------------------------------------------------------------------------- Original Article TUMOUR LOAD IN ADVANCED OVARIAN CANCER PATIENTS AND ITS VALIDATION BY RADIOLOGICAL PERITONEAL CANCER INDEX (PCI) SCORE By Uzma Chishti, Humaira Aziz, Imrana Masroor, Aliya Begum Aziz ABSTRACT Objective: To compare the radiological peritoneal cancer index (PCI) score to the surgical PCI score for validating it as a non-invasive method to predict surgical outcomes. Study Design: A descriptive study. Place and Duration of the Study: Department of Obstetrics and Gynaecology of ... Download PDF Read Full Article View Graphical Abstract -------------------------------------------------------------------------------- Original Article IDENTIFICATION AND VALIDATION OF A NOVEL PANOPTOSIS-RELATED GENE SIGNATURED FOR OSTEOSARCOMA AS PROGNOSTIC MODEL By Xianglin Peng, Wanchun Wang ABSTRACT Objective: To construct and validate a prognostic model for osteosarcoma prognostication and therapeutic potential of PANoptosis- related genes. Study Design: Observational study. Place and Duration of the Study: Department of Orthopaedics, The Second Xiangya Hospital of Central South Unive... Download PDF Read Full Article View Graphical Abstract -------------------------------------------------------------------------------- Original Article CORRELATION OF AIR-BONE GAP ON PURE TONE AUDIOMETRY WITH THE SIZE OF PERFORATION ASSESSED ON OTO-ENDOSCOPY By Aiman Fatima Naqvi, Syeda Uzma Naqvi, Nida Khan, Murtaza Ahsan Ansari, Iqbal A. Muhammad Khyani ABSTRACT Objective: To determine the correlation between the air-bone gap on pure tone audiometry with size of perforation oto-endoscopically. Study Design: A descriptive study. Place and Duration of the Study: Department of ENT - Head and Neck Surgery, Dow University of Health Sciences (DUHS)... Download PDF Read Full Article View Graphical Abstract -------------------------------------------------------------------------------- Original Article PROGNOSTIC VALUE OF PREOPERATIVE SYSTEMIC IMMUNE-INFLAMMATION INDEX IN NON-METASTATIC PAEDIATRIC WILMS' TUMOUR PATIENTS UNDERGOING UPFRONT RADICAL NEPHRECTOMY By Kai Sai, Yi-Bo Ding, Qun Gao ABSTRACT Objective: To analyse the relationship between the preoperative systemic immune-inflammation index (SII) and the relapse-free survival (RFS) of paediatric patients with Wilms' tumour (WT) after radical surgery, and to establish and validate a prognostic survival model. Study Design: Obs... Download PDF Read Full Article View Graphical Abstract -------------------------------------------------------------------------------- Original Article CONGENITAL ANOMALIES OF THE KIDNEY AND URINARY TRACT IN PATIENTS WITH HIRSCHSPRUNG DISEASE By Muniba Mehmood, Jamshed Akhtar, Naima Zamir ABSTRACT Objective: To determine the frequency and types of congenital anomalies of the kidney and urinary tract (CAKUT) in patients with Hirschsprung disease. Study Design: An observational cross-sectional study. Place and Duration of the Study: Department of Paediatric Surgery, National Ins... Download PDF Read Full Article View Graphical Abstract -------------------------------------------------------------------------------- Original Article OUTCOME ANALYSIS OF TRANSPERITONEAL LAPAROSCOPIC NEPHRECTOMY IN CHILDREN: EXPERIENCE FROM A DEVELOPING COUNTRY By Ghulam Mujtaba Zafar, Muhammad Zaheer, Fawad Humayun Akhtar, Sadia Ghias ABSTRACT Objective: To analyse the outcome of laparoscopic nephrectomy among children. Study Design: An observational study. Place and Duration of the Study: Department of Paediatric Urology, Children’s Hospital Lahore, from September 2021 to June 2023. Methodology: During the study, 100 chil... Download PDF Read Full Article -------------------------------------------------------------------------------- Original Article OUTCOMES OF DOUBLE-FACE BUCCAL MUCOSAL URETHROPLASTY FOR TREATING ANTERIOR URETHRAL STRICTURE IN ADULT MALES By Tanzeel Ur Rahman Gazder, Syed Saeed Abidi, Syed Rabiullah, Mazahir Zulfiqar, Usman Qamar, Manzoor Hussain ABSTRACT Objective: To assess the results of double-face buccal mucosal graft urethroplasty (BMG) for treating anterior urethral stricture in adult males. Study Design: An observational study. Place and Duration of the Study: Department of Urology, Sindh Institute of Urology and Transplantation, Kar... Download PDF Read Full Article View Graphical Abstract -------------------------------------------------------------------------------- Meta-Analysis RISK FACTORS FOR CYTOMEGALOVIRUS INFECTION AFTER HAEMATOPOIETIC STEM CELL TRANSPLANTATION: A META-ANALYSIS By Si-Ting Wu, Chun-Li Wang, Li Wang, Cai-Yun Zhang ABSTRACT Cytomegalovirus (CMV) infection is the most common viral infection after haematopoietic stem cell transplantation (HSCT). However, studies on related risk factors give different views without any clear conclusion. Therefore, the purpose of this study was to evaluate the risk variables of CM... Download PDF Read Full Article -------------------------------------------------------------------------------- Meta-Analysis EXPLORING THE SYNERGISTIC EFFECTS OF CONCURRENT EXERCISE FOR MANAGING TYPE-II DIABETES MELLITUS: A META-ANALYSIS By Uroosa Amin, Qurat-Ul-Ain Adnan, Tauseef Ahmad, Sumaira Imran Farooqui ABSTRACT The effectiveness of concurrent exercise (CE) as an emerging approach for type-II diabetes mellitus (T2DM) patients was evaluated through a comprehensive search on Google Scholar, PubMed, Pedro, CINAHL, and Medline from 2015 to March 2023. Sixteen RCTs were selected which evaluated CE (aero... Download PDF Read Full Article -------------------------------------------------------------------------------- Clinical Practice Article PREOPERATIVE ULTRASOUND-GUIDED MARKING, MAMMOGRAM, AND PEROPERATIVE USE OF IMAGE INTENSIFIER: A COST-EFFECTIVE TECHNIQUE IN CLIPPED NON-PALPABLE BREAST CANCER LESIONS TO ACHIEVE ADEQUATE SURGICAL MARGINS By Amna Masud, Huma Majeed Khan, Eisha Tahir, Anam Waseem, Hafsa Ahmed, Rabia Ikram ABSTRACT Objective: To measure the effectiveness of localisation and removal of impalpable target lesions without compromising patient safety in a resource-limited setup using preoperative ultrasound and mammography with peroperative use of C-arm image intensifier. Study Design: Descriptive study. P... Download PDF Read Full Article -------------------------------------------------------------------------------- Clinical Practice Article POSITIONING FOR EMERGENCY LAPAROSCOPIC SPLENECTOMY FOR TRAUMATIC SPLENIC RUPTURE By Hongjun Haung, Zhiqiang Haung, Ruofei Xiong, Xingcheng Meng, Ju Zhang ABSTRACT Objective: To determine whether the right-lateral decubitus or supine position is superior for emergency laparoscopy for traumatic splenic rupture. Study Design: Descriptive study. Place and Duration of the Study: Department of General Surgery, Central Hospital of Shaoxing, Affiliated Hospi... Download PDF Read Full Article -------------------------------------------------------------------------------- Clinical Practice Article MODIFIED DOUBLE-TRACT RECONSTRUCTION IN GASTROINTESTINAL RECONSTRUCTION AFTER PROXIMAL GASTRECTOMY By Yingying Li, Jian Wu, Ming Han, Wenbin Li, Zhibin Bi ABSTRACT Objective: To determine the clinical efficacy and safety of modified double-channel anastomosis for digestive tract reconstruction in proximal gastrectomy for early gastric cancer (EGC). Study Design: Case series. Place and Duration of the Study: Department of Gastrointestinal Surgery, Hej... Download PDF Read Full Article -------------------------------------------------------------------------------- Evidence-Based Report THE EFFICACY AND SAFETY OF TRASTUZUMAB IN THE METASTATIC BREAST CANCER By Xinli Wang, Yan Xue ABSTRACT The aim of this study was to explore the efficacy and safety of Trastuzumab-Deruxtecan (T-DXd) in metastatic breast cancer (mBC). This retrospective observational study was conducted between January 2021 and 2023. Patients’ clinical and pathological characteristics and previous medici... Download PDF Read Full Article -------------------------------------------------------------------------------- Short Article EFFECTS OF SMALL-DOSE ESKETAMINE ON POSTOPERATIVE ANALGAESIA AND SLEEP QUALITY IN PATIENTS WITH TOTAL HIP REPLACEMENT By Qiufeng Wei, Sisi Feng, Weixin Dai, Cheng Xin Lin, Wen Zheng He ABSTRACT Objective: To determine the effect of esketamine in patient-controlled analgaesia after hip replacement on postoperative pain and improve sleep quality in patients. Study Design: Randomised double-blind study. Place and Duration of the Study: Department of Anaesthesiology, The First Affilia... Download PDF Read Full Article -------------------------------------------------------------------------------- Short Communication APPLICATION OF MULTI-SLICE SPIRAL CT RENAL ANGIOGRAPHY COMBINED WITH INTRAOPERATIVE ULTRASOUND IN LAPAROSCOPIC PARTIAL NEPHRECTOMY By Tao Ma, Wentao Wang, Ke Zhang, Wenzeng Yang, Zhen-Yu Cui ABSTRACT This study aimed to evaluate the clinical significance of multi-slice spiral CT renal angiography combined with intraoperative ultrasound in laparoscopic partial nephrectomy. Eighty patients were seen at the Affiliated Hospital of Hebei University from January 2021 to December 2022. The pat... Download PDF Read Full Article -------------------------------------------------------------------------------- Short Communication EFFECT OF TISSUE FRAGMENTS REMAIN IN THE KARMAN CANNULA ON THE HISTOPATHOLOGICAL DIAGNOSIS OF ABNORMAL UTERINE BLEEDING By Omer Tammo, Elif Celik, Enes Celik, Denizhan Bayramoglu, Suleyman Yildiz ABSTRACT The aim of this study was to perform histopathological analysis of residual material in the cannula by endometrial sampling using a Carmen injector, and to compare the results. The study was conducted in the Department of Gynaecology, Mardin Training and Research Hospital, Artuklu/Mardin, T... Download PDF Read Full Article -------------------------------------------------------------------------------- Letter to the Editor BEYOND LAPAROSCOPY: EMBRACING A SCARLESS SOLUTION FOR GALLSTONES “THE NOTES” By Abdul Sami Arain, Muhammad Aliyan Ahmed Sheikh, Ali Ahmed Khoso Download PDF Read Full Article -------------------------------------------------------------------------------- Letter to the Editor DETECTION OF HYPERDIPLOIDY FROM CEREBROSPINAL FLUID IN B-CELL ACUTE LYMPHOBLASTIC LEUKAEMIA By Emine Goktas, Sinan Demircioglu Download PDF Read Full Article -------------------------------------------------------------------------------- Letter to the Editor NODULAR MELANOMA PRESENTING WITH CUTANEOUS HORN AND DISPLAYING RHABDOID FEATURES: AN UNUSUAL PRESENTATION By Asuman Kilitci Download PDF Read Full Article -------------------------------------------------------------------------------- Letter to the Editor SYNCHRONOUS DIAGNOSIS OF ANGIOIMMUNOBLASTIC T-CELL LYMPHOMA AND LUNG NEURO-ENDOCRINE CANCER IN A PATIENT By Guangquan Zhou, Rong Chen Download PDF Read Full Article -------------------------------------------------------------------------------- Letter to the Editor PROSTATE CANCER TREATMENT CANNOT BE ENHANCED WITHOUT INCLUDING COMPREHENSIVE CANCER REHABILITATION By Farooq Azam Rathore Download PDF Read Full Article -------------------------------------------------------------------------------- USEFUL LINKS * JCPSP Latest Articles * JCPSP Search * JCPSP Policies FURTHER INFORMATION * Contact Us * Advertise with Us * CPSP Website GUIDELINES * Processing of Manuscript * Guidelines Qualitative Studies * F.A.Q ABOUT JOURNAL * About JCPSP -------------------------------------------------------------------------------- JCPSP JOURNAL OF THE COLLEGE OF PHYSICIANS & SURGEONS PAKISTAN Copyright © 2015 - 2019 College of Physicians & Surgeons Pakistan. 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