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Text Content

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   NEW MEDICINE: FASTER, SAFER, SMARTER.
   
    
   
   CTi TOKEN
   
   

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   NEW MEDICINE: FASTER, SAFER, SMARTER.
   
    
   
   CTi TOKEN
   
   

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   NEW MEDICINE: FASTER, SAFER, SMARTER.
   
    
   
   CTi TOKEN
   
   

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   NEW MEDICINE: FASTER, SAFER, SMARTER.
   
    
   
   CTi TOKEN
   
   

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CURRENTLY, EFFICIENCY ISSUES IN CLINICAL TRIALS ARE COSTING BETWEEN $600,000 –
$8M DOLLARS PER DAY, AND ARE SIGNIFICANTLY DELAYING THE DELIVERY OF NEW MEDICINE
TO PATIENTS IN NEED.


WE WANT TO CHANGE THAT.

CLINTEX ARE A SOLUTION PROVIDER TO THE PHARMACEUTICAL INDUSTRY, AND THE TEAM
BEHIND CTI – CLINICAL TRIALS INTELLIGENCE:

A new type of software platform aimed at transforming the medicine development
industry through the application of predictive analytics, machine learning, and
the novel use of blockchain technology and smart contracts in clinical trials.

Our mission is to bring down the cost of medicine and improve the speed to
market of new medicines for the people who need them, through vastly reducing
development costs for the global pharmaceutical industry.


AS FEATURED ON:





CLINICAL TRIALS INTELLIGENCE IS A DISTRIBUTED TECHNOLOGY PLATFORM THAT
INCORPORATES PREDICTIVE DATA ANALYTICS, MACHINE LEARNING (AI), AND THE
INNOVATIVE USE OF SMART CONTRACTS TO DRIVE SIGNIFICANT QUALITY AND OPERATIONAL
IMPROVEMENTS IN CLINICAL TRIALS.



DATA ANALYTICS



With the application of powerful and insightful data analytics functionality
across administrative, operational and clinical functions, stakeholders can now
identify, action and resolve the potential issues detected before they 
negatively impact the trial.



ECO-SYSTEM



Clinical Trials Intelligence has created an eco-system that fosters
collaboration across the entire pharmaceutical industry while addressing the
privacy and security concerns of all stakeholders.



CLINICAL DATA



A “first of it’s kind” perpetually increasing library of clinical data analytics
that facilitates the sharing of “lessons learned” across corporate boundaries
without any compromise of sensitive data.



WORKFLOW MANAGEMENT



Advanced workflow management, including “closing the loop” functionality and a
blockchain based immutable audit-trail.



Pharmaceutical companies can now gain deep insight into the operational and
clinical aspects of their trials without the necessity of major investment into
backend technical infrastructure or data science expertise.

ONE PAGE SUMMARY

CLINTEX WHITEPAPER

TECHNICAL PAPER




KEY FEATURES

 * A full history of clinical trial key metrics are stored immutably on Clinical
   Trials Intelligence’s decentralised ledger, where they are used by Clinical
   Trials Intelligence’s App’s to power bespoke predictive analytics algorithms
   in on-going trials on the platform.

 * As Clinical Trials Intelligence is a fully integrated platform that provides
   end-to-end auditable workflow management & oversight in trials, all actions,
   including preventative and corrective actions (CAPA), are recorded on the
   Clinical Trials Intelligence blockchain on an on-going basis.

 * This represents the creation of a clinical eco-system that enables
   interoperability and safe storage of all clinical trial data views, while
   also addressing the privacy and security concerns of all stakeholders.


CTI APPLICATIONS

The CTi eco-system consists of seven separate Apps which each provide invaluable
key insights and immense benefit to stakeholders such as Clinical Project
Managers & Physicians, Clinical Data Managers, Pharmacovigilance staff and Site
Monitors.

CTI-OEM



Operational Excellence

Provides intuitive operational oversight of clinical trials for clinical project
managers, clinical data managers and remote staff, allowing instream
decision-making on what actions are required to ensure a successful project.

CTI-CDV



Clinical Data Visualisations

Provides enhanced clinical data review through the use of data visualisations to
identify issues that may impact on the trial integrity and safety of the patient
e.g. data quality issues, disease exacerbation. Furthermore, CTi-CDV will
facilitate flagging of these issues, and corrective actions to be recorded and
monitored.

CTI-PDA



Predictive Analytics

The CTi-PDA application will combine all operational and clinical data sources
and use predictive modelling to forecast issues and events before they happen.
The CTi-PDA application will reveal hidden correlations across all datasets
thereby facilitating the pharmaceutical company to take pro-active action to
address.

CTI-RBM



Risk Based Monitoring

The CTi-RBM application will use current and historical data to predict specific
risks, and thereby allow for tactical deployment of the pharmaceutical company’s
data and site monitoring resources to take preventative action. This predictive
risk based approach differs from current reactive approaches to risk and can
significantly reduce site monitoring costs during a clinical trial.

CTI-PRR



Patient Recruitment and Retention

The CTi-PRR application manages recruitment and retention of patients for
clinical trials by providing a portal for patient identification and producing a
series of alerts (based on predictive analytics) that flag when a patient is at
risk of withdrawing from the study.

CTI-SIM



Site Investigators

The CTi-SIM application manages the recruitment of investigators (physicians) to
run clinical trials,and manages token payment compensation by the pharmaceutical
company to investigators, triggered by data-driven milestones and KPIs, defined
on Clinical Trials Intelligence.

CTI-VMM



Vendor Management

CTi-VMM provides oversight on data quality and manages token payment
compensation by the pharmaceutical company to the third party vendors, triggered
automatically by data-driven milestones and KPIs, defined on Clinical Trials
Intelligence.




MEET OUR TEAM

Combining the best of expertise from across the pharmaceutical, clinical,
software development and data analytics spectrum.

ANDRE BYRNE
Chief Operating Officer



READ BIO

Andre has been involved in the startup world since an early age, having founded
a successful media development company at the age of 22.

Coming from a strongly technical background in programming, network deployment
and online marketing, his interest in blockchain spans back to 2014 when he made
his first investments in Bitcoin and Ethereum and fell in love with the world of
decentralized technology.

NEILL BARRON
Director of Clinical Data Analytics



READ BIO

Neill leads the requirements specification, design and development of the CTi
platform, ensuring it meets current and future real-world challenges for the
pharmaceutical industry.

He has over 20 years broad clinical development experience through a blend of
senior roles in clinical data management, data analytics, technical/process
improvement and site data monitoring.

ETHAN DIAMANT
Director of Clinical Data Services



READ BIO

Ethan is leading the Clinical Trial Services function, responsible for building
partnerships with the pharmaceutical industry, and ensuring that evolving
customer requirements are built into ClinTex’s products and services.

Ethan has 19 years experience working directly in clinical trials including
clinical data monitoring, study optimization and global operational excellence.

MATTHEW BUCKLEY
Trial Optimisation Manager



READ BIO

Matthew Buckley, Manager, Clinical Trial Optimisation - Matthew graduated from 
Leeds University with a BEng in Process and Chemical Engineering, and started
working in the clinical trial space as a Data Manager in 2017.  He quickly
progressed to applying his engineering background to process improvement in
clinical trials, having led a number of efficiency initiatives. His practical
experience in this area is a welcome addition to the ClinTex team, where his
skills will be used in the application of CTi to improve clinical trial
efficency.

BRENDAN MANNION
Non Executive Director



READ BIO

Brendan is a highly experienced project manager and business analyst with
extensive experience in financial operations, telecommunications & consumer
marketing.

Successful proven leadership skills, he enjoys working with people to solve
problems. Brendan has had an interest in the blockchain space since 2013 and
intertwines this experience with his business expertise regularly in his role as
a director in ClinTex.

JOHN MCCABE
Head of Legal & Regulatory



READ BIO

John holds a BA (Hons) in Business Law and is a licenced solicitor in England,
Wales and Ireland after being admitted into the Law Society of Ireland in 2013.

John has been working in law for over eleven years and has a keen interest in
all things blockchain. He is excited to be bringing his focus to the
cryptocurrency legal and regulatory landscape.

IAN HARRIGAN
Senior Developer



READ BIO

Ian joins the team as a top level systems architect and developer with
experience building solutions for NHS contractors and designing various desktop
and web applications as well as complex distributed back end systems.

Ian has spearheaded ClinTex' Optex development on the ICP, in association with
the DFINITY foundation

SHILPY GOYAL
Data Analytics Developer



READ BIO

Shilpy holds over 10 years of experience in analytics, visualising data, data
cleaning and machine learning.

She has worked in various domains such as telecommunications, healthcare, and
energy, and ClinTex are delighted to have her oversight and expertise and she
works to build on CTi's existing data models and visualisations.

SEAN COMISKEY
Technology Engineering Advisor



READ BIO

Sean is highly motivated software engineer with experience covering the full
software development life cycle, with particular specialisation in event
sourcing and CQRS.

He brings excellent understanding of modern software development principles,
practices and paradigms to the ClinTex advisory board.




WHO WE WORK WITH

INTELLIMED

An innovative health-tech company focusing on streamlining UK National Health
Service (NHS) processes, reducing costs and improving patient care. Intellimed
is part of the Serendip Digital Health quarter based at the Innovation
Birmingham Campus, and will be a valuable partner for CTi Platform deployments
in healthcare and clinical research settings.

GLOBAL BLOCKCHAIN CONSORTIUM

The GBC has been established with the mission of promoting blockchain awareness
and education in the areas of fintech, disruptive tech and blockchain
technologies. The GBC errand is to work in strategic collaboration with
organisations and individuals that are revolutionising leading practices and
wider adaptation of fintech and blockchain technologies elucidation to aid wider
society.

KUCOIN EXCHANGE

Founded in September 2017, KuCoin has grown into one of the most popular crypto
exchanges, and it currently provides a series of financial services including
fiat-to-crypto, crypto-to-crypto, futures, staking, borrowing, token launch and
more to its 6 million users across 207 countries and regions around the world.
One out of four crypto holders worldwide is with KuCoin.

TIBCO

ClinTex are partnering with Tibco to utilise their Spotfire visualisation
software to display the various analytics generated from the CTi data model.
TIBCO Spotfire® allows users to combine data in a single analysis , and delivers
AI-driven interactive visuals that will help identify the main causes of
clinical trial inefficiency.

SUM & SUBSTANCE

Sum & Substance are a pioneer in the Trusted Digital Identity space that
specialise in identity proofing, risk-based authentication, regulatory
identification, and the detection and prevention of the use of stolen
identities, ensuring a robust and comprehensive risk and compliance solution.

BEOSIN

Beosin is a well respected and experienced blockchain technology firm offering a
full spectrum solution from tactical technical execution to high-level
theoretical modelling, with a speciality in the auditing of smart contracts for
blockchain projects.

STERLING LAW

Sterling Law is a modern and innovative boutique law firm with cross-domain
specialisation that allows for seamless solutions to solve complex problems.





CTI DEVELOPMENT ROADMAP

The development of Clinical Trials Intelligence from concept to completion.

2021

Q1 |
CTi-PDA Specification Development


Q2 |
CTi-OEM GUI Development & Testing


Q3 |
CTi-OEM MVP Launch


Q4 |
OpTex & PDA Development / Testing

2022

Q1 |
CTi-PDA GUI Development & MVP Launch
Optex MVP alpha target

Q2 |
Migration on-chain of CTi Clinical Data Statistical Summaries


Q3 |
Industry Pilots – Development of Visual Specs for Clinical Trial Launch

Q4 |
Launch CTi into active clinical trial


2018

Q1 |
Ideation & Research

Q2 |
Concept Development

Q3 |
Development Sprint 1 ‘Minimum Viable Product’
Whitepaper Published

Q4 |
Industry Consultation on CTi Prototype
Core Team Established

2019

Q1 |
Development
Sprint 2 ‘Enhancement’


Q3 |
Proof of Concept

Q4 |
Strategic Partnerships Agreed

Q2 |
CTi Data Model Finalised


2020

Q1 |
System Requirements Evaluation
Private Funding Round

Q2 |
CTi-OEM Specification Development

Q3 |
CTi-OEM Prototype Development & Testing
Public Token Sale

Q4 |
Standardisation of CTi Data model to SDTM

2021

Q1 |
CTi-PDA Specification Development


Q2 |
CTi-OEM GUI Development & Testing


Q3 |
CTi-OEM MVP Launch


Q4 |
OpTex & PDA Development / Testing

2022

Q1 |
CTi-PDA GUI Development & MVP Launch
Optex MVP alpha target

Q2 |
Migration on-chain of CTi Clinical Data Statistical Summaries


Q3 |
Industry Pilots – Development of Visual Specs for Clinical Trial Launch

Q4 |
Launch CTi into active clinical trial


2018

Q1 |
Ideation & Research

Q2 |
Concept Development

Q3 |
Development Sprint 1 ‘Minimum Viable Product’
Whitepaper Published

Q4 |
Industry Consultation on CTi Prototype
Core Team Established

2019

Q1 |
Development
Sprint 2 ‘Enhancement’


Q3 |
Proof of Concept

Q4 |
Strategic Partnerships Agreed

Q2 |
CTi Data Model Finalised



ABOUT US



ClinTex deliver intuitive blockchain-based self service analytic solutions to
the pharmaceutical industry.

At ClinTex, our novel Clinical Trials Intelligence solution will enhance
clinical trial processes by providing tools to optimise Operational Efficiency,
Clinical Data Quality and Medical Review.

eClinTex t/a Clintex Limited (Estonia)
Juhkentali 8, Tallinn 10132, Estonia

Estonia Business Number 14991810


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Ian Harrigan@IanHarrigan1982

#haxeui v1.5 (finally) released! With its usual write up here:
https://community.haxeui.org/t/haxeui-v1-5-released

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Our onboarding process at LVL Health consists of four important steps to arrange
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