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Print your offer today.

Print your offer today. If you are unable to see the message below, view the web
version here.

Please see U.S. Full Prescribing Information, including Boxed WARNINGS and
Medication Guide.

ELIQUIS (apixaban) is a prescription medicine used to reduce the risk of stroke
and blood clots in people who have atrial fibrillation (AFib), a type of
irregular heartbeat, not caused by a heart valve problem.

ELIQUIS is a prescription medicine used to treat blood clots in the veins of
your legs (deep vein thrombosis) or lungs (pulmonary embolism), and reduce the
risk of them occurring again.

ELIQUIS is a prescription medicine used to reduce the risk of forming a blood
clot in the legs and lungs of people who have just had hip or knee replacement
surgery.

See below for ELIQUIS Important Safety Information

Your Co-pay Card is
one click away



Your Co-pay Card is one click away

Dear Patricia, Thank you for signing up. This e-mail provides a link to your
Co-pay Card for ELIQUIS® (apixaban). Your Co-pay Card can help you save on the
cost of ELIQUIS. With it, eligible patients may pay as little as $10 a month*†
on a prescription.

SELECTED IMPORTANT SAFETY INFORMATION For people taking ELIQUIS (apixaban) for
atrial fibrillation: Do not stop taking ELIQUIS without talking to the doctor
who prescribed it for you. Stopping ELIQUIS increases your risk of having a
stroke. ELIQUIS can cause bleeding, which can be serious and rarely may lead to
death. This is because ELIQUIS is a blood thinner medicine that reduces blood
clotting. Spinal or epidural blood clots (hematoma). People who take ELIQUIS,
and have medicine injected into their spinal and epidural area, or have a spinal
puncture have a risk of forming a blood clot that can cause long-term or
permanent loss of the ability to move (paralysis). Please see additional
Important Safety Information, including Boxed WARNINGS, for ELIQUIS below.

Print your Co-pay Card

If you haven’t already printed a copy of your Co-pay Card, you can click here
now to print a temporary card for immediate use. You’ll also be receiving a hard
copy of your Co-pay Card in the mail, if requested.



As a reminder, your card has been activated and is ready to use. Just go ahead
and bring it to your pharmacy with a valid prescription for ELIQUIS from your
doctor.

* Eligibility requirements and terms of use apply. Please see Eligibility
Requirements and Terms of Use below.

† Patient is responsible for applicable taxes, if any.

As a reminder, your card has been activated and is ready to use. Just go ahead
and bring it to your pharmacy with a valid prescription for ELIQUIS from your
doctor.

* Eligibility requirements and terms of use apply.

† Please see Eligibility Requirements and Terms of Use below.



Eligibility Requirements: You may be eligible for the Co-pay Card for ELIQUIS®
(apixaban) if:

1. You are insured by commercial insurance and your prescription insurance
coverage does not cover the full cost of your prescription, that is, you have a
co-pay obligation for ELIQUIS;

2. You do not have prescription insurance coverage through a state or federal
healthcare program, including but not limited to Medicare Part D, Medicaid,
Medigap, Veterans Affairs (VA), or Department of Defense (DOD) programs;
patients who move from commercial plans to state or federal healthcare programs
will no longer be eligible;

3. You are 18 years of age or older; and

4. You are a resident of the United States or Puerto Rico.

Terms of Use:

1. Eligible patients who present an activated Co-pay Card together with a valid
prescription for ELIQUIS at participating pharmacies may pay as little as $10
per 30‑day supply (up to 74 tablets for the first fill and up to 60 tablets for
all subsequent fills) for up to 24 months, subject to a maximum annual benefit
of $3800. Other restrictions may apply. Patient is responsible for applicable
taxes, if any.

2. Offer not applicable to co-pays of $10 or less.

3. Patients, pharmacists, and prescribers cannot seek reimbursement, from health
insurance or any third party, for any part of the benefit received by the
patient through this offer.

4. Your acceptance of this offer confirms that this offer is consistent with
your insurance and that you will report the value received as may be required by
your insurance provider.

5. Card must be activated before use. Activation and first use of the Co‑pay
Card must take place by December 31, 2022. Card expires 24 months from
activation. Upon expiration, eligible patients may re‑enroll in the Co‑pay Card
Program.

6. All Program payments are for the benefit of the patient only.

7. Only valid in the United States and Puerto Rico; this offer is void where
restricted or prohibited by law.

8. This offer is non‑transferable, no substitutions are permissible, and offer
cannot be combined with any other rebate/coupon, free trial, or similar offer
for the specified prescription.

9. The Co-pay Card may not be sold, purchased, traded, or counterfeited.
Reproductions of this Co-pay Card are void.

10. Bristol Myers Squibb and Pfizer reserve the right to rescind, revoke, or
amend this offer at any time without notice.

11. This offer is not conditioned on any past, present, or future purchase,
including refills.

12. No membership fees.

13. The Co-pay Card for ELIQUIS is not health insurance.

The Co‑pay Card will be accepted only at participating pharmacies. For those
customers using mail order or any non‑participating retail pharmacy, please call
866‑279‑4730 to request a patient rebate form, or go to
www.patientrebateonline.com to download a form. Questions can also be submitted
via mail to: PO Box 2914 Phoenix, AZ, 85062‑2914. BY USING THIS CARD, YOU AND
YOUR PHARMACIST UNDERSTAND AND AGREE TO COMPLY WITH THESE ELIGIBILITY
REQUIREMENTS AND TERMS OF USE. To the pharmacist: For processing assistance,
please call McKesson Pharmacy Support at 1‑866‑279‑4730. For more information
about ELIQUIS, visit ELIQUIS.com.

  Important facts about ELIQUIS® (apixaban): This is a summary of important
information that you need to know about ELIQUIS.

Do not stop taking ELIQUIS without talking to the doctor who prescribed it to
you

For patients taking ELIQUIS for atrial fibrillation: stopping ELIQUIS increases
your risk of having a stroke.

Talk to your healthcare team before any medical procedures. ELIQUIS may need to
be stopped before surgery, or a medical or dental procedure. Your doctor will
tell you when you should stop taking ELIQUIS and when you may start taking it
again. If you have to stop taking ELIQUIS your doctor may prescribe another
medicine to help prevent a blood clot from forming.

Look out for
the following
icons as you
read:



Talk to your
healthcare
team



Call a
healthcare
provider right
away



Helpful
information
to remember

Look out for the following icons as you read:

Talk to your healthcare team



Call a healthcare provider right away



Helpful information to remember



What are the possible serious side effects of ELIQUIS? This is a list of some of
the serious side effects of ELIQUIS.

Bleeding ELIQUIS can cause bleeding, which can be serious, and rarely may lead
to death. This is because ELIQUIS is a blood thinner medicine that reduces blood
clotting. While taking ELIQUIS, you may bruise more easily and it may take
longer than usual for any bleeding to stop. You may have a higher risk of
bleeding if you take ELIQUIS with other medicines that increase your risk of
bleeding, such as:

Bleeding

ELIQUIS can cause bleeding, which can be serious, and rarely may lead to death.
This is because ELIQUIS is a blood thinner medicine that reduces blood clotting.
While taking ELIQUIS, you may bruise more easily and it may take longer than
usual for any bleeding to stop. You may have a higher risk of bleeding if you
take ELIQUIS with other medicines that increase your risk of bleeding, such as:

• Aspirin

• Nonsteroidal anti-
inflammatory drugs
(called NSAIDs)

• Warfarin

• Heparin

• Selective serotonin
reuptake inhibitors
(SSRIs) or serotonin
norepinephrine
reuptake inhibitors
(SNRIs)

• Other medicines
to help prevent or
treat blood clots

• Aspirin • Nonsteroidal anti-inflammatory drugs (called NSAIDs) • Warfarin •
Heparin • Selective serotonin reuptake inhibitors (SSRIs) or serotonin
norepinephrine reuptake inhibitors (SNRIs) • Other medicines to help prevent or
treat blood clots

Tell your doctor if you take any of these medicines.

Call your doctor or get medical help right away if you have any of these signs
or symptoms of bleeding when taking ELIQUIS:

• Unexpected bleeding
or bleeding that lasts
a long time, such as:

Unusual bleeding
from the gums

Nosebleeds that
happen often

Menstrual or
vaginal bleeding
that is heavier
than normal

• Bleeding that is
severe or you
cannot control

• Red, pink, or
brown urine

• Red or black
stools (looks like
tar)

• Coughing up or
vomiting blood

• Vomit that looks
like coffee grounds

• Unexpected pain,
swelling, or joint
pain

• Headaches

• Feeling dizzy or
weak

• Unexpected bleeding or bleeding that lasts a long time, such as:

Unusual bleeding from the gums Nosebleeds that happen often Menstrual or vaginal
bleeding that is heavier than normal

• Bleeding that is severe or you cannot control • Red, pink, or brown urine •
Red or black stools (looks like tar) • Coughing up or vomiting blood • Vomit
that looks like coffee grounds • Unexpected pain, swelling, or joint pain •
Headaches • Feeling dizzy or weak

Spinal or epidural blood clots (hematoma)

People who take ELIQUIS, and have medicine injected into their spinal or
epidural area, or have a spinal puncture, have a risk of forming a blood clot
that can cause long‑term or permanent loss of the ability to move (paralysis).
Your risk of developing a spinal or epidural blood clot is higher if:

• A thin tube called an
epidural catheter is
placed in your back
to give you certain
medicine

• You take NSAIDs
or a medicine to
prevent blood
from clotting

• You have a history
of difficult or
repeated epidural
or spinal punctures

• You have a history
of problems with
your spine, or have
had surgery on
your spine

• A thin tube called an epidural catheter is placed in your back to give you
certain medicine • You take NSAIDs or a medicine to prevent blood from clotting
• You have a history of difficult or repeated epidural or spinal punctures • You
have a history of problems with your spine, or have had surgery on your spine

If you take ELIQUIS and receive spinal anesthesia or a spinal puncture, your
doctor should watch you closely for symptoms of spinal or epidural blood clots
or bleeding.

Tell your doctor right away if you have any of these signs or symptoms
(especially in your legs and feet) when taking ELIQUIS:

• Tingling

• Numbness

• Muscle weakness

• Tingling • Numbness • Muscle weakness

A reaction to ELIQUIS itself A reaction to ELIQUIS can cause hives, rash,
itching, and possibly trouble breathing. If you get this reaction, it will
usually happen soon after you take a dose of ELIQUIS.

Get medical help right away if you have any of the following symptoms:

• Sudden chest pain
or chest tightness

• Sudden swelling of
your face or tongue

• Trouble breathing

• Wheezing

• Feeling dizzy or
faint

• Sudden chest pain or chest tightness • Sudden swelling of your face or tongue
• Trouble breathing • Wheezing • Feeling dizzy or faint

Talk to your doctor about any side effect that may be bothering you or that does
not go away. These are not all of the possible side effects of ELIQUIS. Call
your doctor for medical advice about side effects.

You are encouraged to report any side effects to the FDA at
1-8 00-F DA-1 088.



Who should not take ELIQUIS?

ELIQUIS is not for patients who:

• have artificial heart
valves.

• have
antiphospholipid
syndrome (APS),
especially with
positive triple
antibody testing,
who have a history
of blood clots.

• currently have
certain types of
abnormal bleeding.

• have had a serious
allergic reaction to
ELIQUIS.

• have artificial heart valves. • have antiphospholipid syndrome (APS),
especially with positive triple antibody testing, who have a history of blood
clots. • currently have certain types of abnormal bleeding. • have had a serious
allergic reaction to ELIQUIS.



What should I discuss with my healthcare team before starting ELIQUIS?

Talk to your healthcare team about the following:

• Kidney or liver
problems

• If you have antiphospholipid syndrome

• Any other medical conditions

• If you have ever
had bleeding
problems

• Kidney or liver problems • If you have antiphospholipid syndrome • Any other
medical conditions • If you have ever had bleeding problems

Tell your doctor if you are pregnant or breastfeeding, or planning to become
pregnant or breastfeed. You and your doctor should decide if you will take
ELIQUIS or breastfeed. You should not do both. Females who are able to become
pregnant: talk with your healthcare provider about pregnancy planning, and your
risk of severe uterine bleeding if you are treated with blood thinner medicines,
including ELIQUIS.

Tell your healthcare team about all of the medications you are taking,
including:

• Prescriptions

• Over-the-counter
medicines

• Herbal supplements

• Vitamins

• Prescriptions • Over-the-counter medicines • Herbal supplements • Vitamins

During treatment, make sure you talk to your healthcare team before you begin to
take any new medication.



How should I take ELIQUIS?

Take ELIQUIS exactly as prescribed by your doctor.

Twice daily With or without food

Twice daily

With or without food

Do not change your dose or stop taking ELIQUIS unless your doctor tells you to.

What if I miss a dose of ELIQUIS?

If you miss a dose of ELIQUIS, take it as soon as you remember, and do not take
more than one dose at the same time.

When should I refill my prescription?

If you are taking ELIQUIS for atrial fibrillation, stopping ELIQUIS may increase
your risk of having a stroke. Do not run out of ELIQUIS. Refill your
prescription before you run out. When leaving the hospital following hip or knee
replacement, be sure that you will have ELIQUIS available to avoid missing any
doses.

ELIQUIS is available in two different tablets. Your doctor or healthcare
provider will determine what dose is right for you. On one side of each tablet,
there is a number indicating the dosage strength of the tablet (in milligrams).
On the other side, there is a medication identification number.

2.5 mg tablet

Round, with a pale yellow color

OR

5 mg tablet

Oval, with a pale orange or pink color

2.5 mg tablet

Round, with a pale yellow color

OR

5 mg tablet

Oval, with a pale orange or pink color

Note: Images do not represent actual tablet size.

On one side of each tablet, there is a number indicating the dosage strength of
the tablet (in milligrams). On the other side, there is a medication
identification number.



What is ELIQUIS? ELIQUIS is a prescription medicine used to:

Reduce the risk of stroke and blood clots in people who have atrial fibrillation
(AFib), a type of irregular heartbeat, not caused by a heart valve problem.

Reduce the risk of stroke and blood clots in people who have atrial
fibrillation (AFib), a type of irregular heartbeat, not caused by a heart valve
problem.

Treat blood clots in the veins of the legs (deep vein thrombosis – DVT) or lungs
(pulmonary embolism – PE), and reduce the risk of them occurring again.

Treat blood clots in the veins of the legs (deep vein thrombosis – DVT) or lungs
(pulmonary embolism – PE), and reduce the risk of them occurring again.

Reduce the risk of forming a blood clot in the legs (DVT) and lungs (PE) of
people who have just had hip or knee replacement surgery.

Reduce the risk of forming a blood clot in the legs (DVT) and lungs (PE) of
people who have just had hip or knee replacement surgery.

Please see U.S. Full Prescribing Information, including Boxed WARNINGS and
Medication Guide.

The product information provided in this email is intended only for residents of
the United States. The products discussed herein may have different product
labeling in different countries. The health information contained herein is
provided for educational purposes only and is not intended to replace
discussions with a healthcare provider. All decisions regarding patient care
must be made with a healthcare provider, considering the unique characteristics
of the patient. You are encouraged to report negative side effects of
prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call
1-800-FDA-1088. For more information about ELIQUIS, visit www.ELIQUIS.com.
Sincerely, The ELIQUIS 360 Team





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calling
1‑ 8 7 7 ‑ 9 2 0 ‑ 1 9 0 4, or mailing your request to Bristol Myers Squibb,
P.O. Box 925, Palatine, IL 60078‑0925.



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ELIQUIS® and the ELIQUIS logo are trademarks of Bristol-Myers Squibb Company.
All other trademarks are property of their respective companies. © 2021
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