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ALLIANCE FOR THE PRUDENT USE OF ANTIBIOTICS
 * Home
 * About Us ISAC / APUA Merger APUA Board Individual membership Organisational
   members Join APUA What We Do Our History APUA Publications APUA / ISAC
   Reception Contact Us
 * About the Issue General Background Science of Resistance Glossary
 * Policy APUA in Action Antibiotic Use in Food Animals Antibiotics and
   Nutrition Other Initiatives International Development
 * Research Research Competencies Representative Projects
 * Resources Antibiotic cards Antibiotic cards - vietnamese Consumers Educators
   Practitioners References
 * News APUA Newsletter Latest APUA News Antibiotic Resistance in the News World
   Antibiotic Awareness Week Tributes to Prof. Stuart Levy APUA Webinars In
   Memorium APUA Leadership Award Archives

 * Home/
 * About Us/
    * ISAC / APUA Merger
    * APUA Board
    * Individual membership
    * Organisational members
    * Join APUA
    * What We Do
    * Our History
    * APUA Publications
    * APUA / ISAC Reception
    * Contact Us

 * About the Issue/
    * General Background
    * Science of Resistance
    * Glossary

 * Policy/
    * APUA in Action
    * Antibiotic Use in Food Animals
    * Antibiotics and Nutrition
    * Other Initiatives
    * International Development

 * Research/
    * Research Competencies
    * Representative Projects

 * Resources/
    * Antibiotic cards
    * Antibiotic cards - vietnamese
    * Consumers
    * Educators
    * Practitioners
    * References

 * News/
    * APUA Newsletter
    * Latest APUA News
    * Antibiotic Resistance in the News
    * World Antibiotic Awareness Week
    * Tributes to Prof. Stuart Levy
    * APUA Webinars
    * In Memorium
    * APUA Leadership Award
    * Archives




ALLIANCE FOR THE PRUDENT USE OF ANTIBIOTICS

 * Home/
 * About Us/
    * ISAC / APUA Merger
    * APUA Board
    * Individual membership
    * Organisational members
    * Join APUA
    * What We Do
    * Our History
    * APUA Publications
    * APUA / ISAC Reception
    * Contact Us

 * About the Issue/
    * General Background
    * Science of Resistance
    * Glossary

 * Policy/
    * APUA in Action
    * Antibiotic Use in Food Animals
    * Antibiotics and Nutrition
    * Other Initiatives
    * International Development

 * Research/
    * Research Competencies
    * Representative Projects

 * Resources/
    * Antibiotic cards
    * Antibiotic cards - vietnamese
    * Consumers
    * Educators
    * Practitioners
    * References

 * News/
    * APUA Newsletter
    * Latest APUA News
    * Antibiotic Resistance in the News
    * World Antibiotic Awareness Week
    * Tributes to Prof. Stuart Levy
    * APUA Webinars
    * In Memorium
    * APUA Leadership Award
    * Archives




ALLIANCE FOR THE PRUDENT USE OF ANTIBIOTICS



Mission Statement
The mission of the Alliance for the Prudent Use of Antibiotics (APUA) is to
strengthen global defenses against infectious disease by ensuring access to
effective treatment and promoting appropriate antibiotic use to contain drug
resistance. With a network of affiliated colleagues, APUA stands as the world’s
leading organisation conducting research and education on antimicrobial
treatment and resistance at the grassroots and global levels.

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AMR IN LOW RESOURCE SETTINGS AND / OR DISPLACED POPULATIONS WEBINAR



22 October at 17.00 CET

The joint ISAC / ESCMID webinar which aims to explore the challenges of
antimicrobial resistance (AMR) in low-resource settings and displaced
populations, highlighting practical solutions for infection control is happening
tomorrow. It seeks to promote global collaboration and innovative strategies to
address AMR in these vulnerable communities. Join our expert panelists who will
shine the spotlight on AMR in resource challenged areas and populations.

Speakers: Dr Rana Hajjeh, Dr Guido Granata
Moderators: Prof. Souha Kanj, Prof. Robert Skov

Register

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ISAC/APUA NEWSLETTER - SPECIAL UNGA EDITION

The International Society of Antimicrobial Chemotherapy (ISAC) and the Alliance
for the Prudent Use of Antibiotics (APUA) are delighted to share a special issue
of ISAC / APUA Newsletter to mark the important occasion of the United Nations
General Assembly High-Level Meeting on AMR taking place today (26 September) in
New York.

The meeting is an opportunity for world leaders to collectively address
the urgent threat AMR poses to global health, food security and achieving the
2030 Sustainable Development Goals.



After demonstrating its continued commitment to fighting antimicrobial
resistance, ISAC received special accreditation to attend. Representing ISAC at
the meeting is Prof. David Jenkins (ISAC Executive Committee member).

Read his editorial on the proposed Declaration which is the main focus of
today's UNGA high-level AMR meeting.

 1. United Nations General Assembly High-Level Meeting on AMR
    David Jenkins

 2. Antibiotic shortages: an overview
    Huong Vu Thi Lan, Miki Nagao, Fatima Allaw, Linus Ndegwa, Gabriel Levy
    Hara, Souha S. Kanj, Pierre Tattevin

 3. Antimicrobial stewardship: a One Health perspective
    Fatma Abdelaziz Amer and Manar G. Gebriel

 4. The development of the ABX Guide: a pathogen-directed consensus guideline
    for antimicrobial use in resource-constrained settings
    Hind Kadri, Neda Milevska-Kostova, Souha Kanj, Heiman Wertheim

The newsletter also features details on ISAC and APUA's latest free educational
activities. Please email secretariat@isac.world with any suggestions for future
articles. View / download the newsletter here

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APUA WEBINARS | INVITATION TO ATTEND



We are pleased to share details of two short webinars hosted by the Alliance for
the Prudent Use of Antibiotics (APUA) happening next week. We are hosting two
webinars to ensure we cover as many time zones as possible.

The main aim of these webinars is to identify and prioritise the objectives of
existing APUA members. But we also invite colleagues interested in joining APUA
to attend.

There will be a short introduction / overview of ISAC and APUA and a
presentation from one of our Project Grant Awardees. The majority of the webinar
will be devoted to group discussion so we can decide how we can best serve our
members.

To attend the webinars, please register using the links below. There are two
registration links so if you want to join both webinars, please sign up to each
one).
Places are limited and existing members will receive priority.

18 September, 17.00 - 18.00 CET
REGISTER

19 September, 10.00 - 11.00 CET
REGISTER

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INTRODUCING THE ABX GUIDE



We are excited to announce a series of six webinars to mark the launch of the
ABX Guide, an open-access antibiotic treatment guideline focused on
pathogen-directed treatment in resource-constrained settings. The ABX Guide will
be accessible through an open access website.

These webinars will delve into the relevance of the ABX Guide and the
development process behind its treatment recommendations. We will explore its
application across various geographic regions, featuring speakers who will
highlight related projects and initiatives. Join us to engage with experts and
stakeholders in the field, and contribute to advancing global health through
informed antibiotic stewardship.

The next webinar in the series to launch the ABX Guide, an open-access
antibiotic treatment-guide focussed on pathogen-directed treatment for
resource-constrained settings, is taking place on 17 September.

Register

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ANTIBIOTIC SUSCEPTIBILITY PATTERNS USED FOR EPIDEMIOLOGIC SURVEILLANCE OF
STAPHYLOCOCCUS AUREUS



There have been recent studies in the US and Spain showing emerging resistance
in MSSA to macrolides and to tetracyclines. ST398 S. aureus strains, initially
identified as “livestock associated MRSA” are a fascinating example. Studies of
clinical S. aureus strains have in some cases included molecular epidemiology
suggesting that ST398 S. aureus strains may be responsible for a change in the
relative prevalence of strains causing clinically significant disease. Other
studies have examined national or transnational emergence of various
increasingly common strains of MRSA and MSSA, using susceptibility patterns to
track strain emergence or change over time. Listen to this webinar and hear from
3 experts in the field on these topics.

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TRAVEL GRANTS TO ATTEND 33RD ICC



There is only ONE week to submit abstracts and apply for travel grants to attend
the 33rd International Congress of Antimicrobial Chemotherapy (ICC) in Istanbul,
Turkey from 3 - 6 November 2024.
All accepted abstracts will be published in ISAC’s open access journal,
the Journal of Global Antimicrobial Resistance (JGAR).

There are three types of awards are available:

ISAC Young Investigator Travel Awards

 * ISAC YITAs are available to applicants from ISAC Member Societies.

 * Applicants must be under the age of 35 years at the time of the congress.

ICC Young Investigator Travel Awards

 * ICC YITAs are available to colleagues in Türkiye and neighbouring countries.

 * Applicants must be under the age of 35 years at the time of the congress.


EASTERN EUROPEAN TRAVEL GRANTS

 * Colleagues residing in Eastern Europe are invited to apply for travel grants
   to attend the ICC.

 * Applicants from relevant ISAC Member Societies and abstract submitters will
   be given priority.

 * Applicants at all stages of their careers are invited to apply and there are
   no age restrictions.

Deadline: 26 July 2024

More details

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ON-DEMAND | ANTIFUNGAL RESISTANCE IN CANDIDA AND ASPERGILLUS



Fungal infections, in their various manifestations, affect millions of people
worldwide and cause a very high morbidity and mortality. The new threats in the
field of invasive mycoses and the new drugs recently available are reviewed in
this webinar by internationally recognised experts.

1. Epidemiology of Fungal Infections with a focus in antifungal resistance - Dr
Ana Alastruey-Izquierdo
2. Detection of antifungal resistance: from MICs to SNPs - Dr Jesús Guinea
3. Clinical impact & new therapeutic options for managing antifungal resistant
fungi - Dr Antonio Vena

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ANTIBIOTIC CARDS - VIETNAMESE TRANSLATIONS



We are delighted to share the Vietnamese translations of five cards for
antibiotics commonly used in Vietnam.

We are very grateful to our colleagues from the Antimicrobial Stewardship
Research Collaboration between Oxford University Clinical Research Unit and the
National Hospital for Tropical Diseases Vietnam for translating these cards.

Download cards

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ANTIFUNGAL RESISTANCE IN CANDIDA AND ASPERGILLUS

Fungal infections, in their various manifestations, affect millions of people
worldwide and cause a very high morbidity and mortality.
The new threats in the field of invasive mycoses and the new drugs recently
available will be reviewed in our next webinar by internationally recognised
experts.

Join us at the next free ISAC webinar on 10 June.

register

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ISAC / APUA NEWSLETTER - SPRING 2024

The International Society of Antimicrobial Chemotherapy (ISAC) and the Alliance
for the Prudent Use of Antibiotics (APUA) are delighted to share the latest
issue of the ISAC / APUA Newsletter.

This issue contains three excellent feature articles:



 1. Identifying targets for antibiotic utilisation for the management of
    resistant pathogens in hospital settings: a threshold logistic modelling
    approach
    Mamoon A. Aldeyab, Stuart E. Bond, William J. Lattyak and Ian Gould

 2. Hand hygiene: playing the “trump card”
    Fatma Abdelaziz Amer and Rehab M. Elsaid Tash

 3. Examining contextual determinants for antimicrobial stewardship in hospital
    settings in an LMIC in Asia: experience from Vietnam
    Huong Vu, Duong Hai Yen, Elizabeth Dodds Ashley, Deverick J. Anderson,
    Nguyen Trung Cap, Pham Ngoc Thach and H Rogier van Doorn

The newsletter also features information on all ISAC and APUA's latest free
educational iniatiatives.

Please email secretariat@isac.world with any suggestions for future articles.

Read / download newsletter

--------------------------------------------------------------------------------


ANTIBIOTIC CARDS

We are pleased to share the next five antibiotic summary cards in the series.
You can now download the following cards for free:

Cefepime, Ceftazidime-Avibactam, Ciprofloxacin, Levofloxacin,
Piperacillin-Tazobactam

All other cards in the series can still be donwloaded.

The cards have so far been downloaded over 10,000 times from countries around
the world.

Download cards


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APUA ON LINKEDIN

APUA is now on Linkedin. Keep up to date with the latest news on APUA’s
activities and other likeminded organisations who promote the prudent use of
antibiotics and aim to combat resistance around the world.

Follow on Linkedin

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CALL FOR APUA MEMBERS

APUA currently has a Board of elected international members. To further promote
and highlight global AMS / AMR issues, APUA is now expanding its individual
membership which is open to individuals with an interest in this field.
Non-governmental organisations with aims similar to APUA are welcome to apply
also.



APUA Membership is free and will put you at the heart of an international
network to advocate for better use of antibiotics.

Membership offers several benefits including the following:

• The opportunity to share and collaborate on projects with colleagues globally.
• To participate in APUA webinars, position papers and other initiatives.
• To communicate and publish in the popular ISAC / APUA newsletters.

Read the full statement here.

APPLY HERE

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JUST PUBLISHED | ISAC / APUA NEWSLETTER

The International Society of Antimicrobial Chemotherapy (ISAC) and the Alliance
for the Prudent Use of Antibiotics (APUA) are delighted to share a special issue
of the ISAC / APUA Newsletter to mark World Antimicrobial Awareness Week 2023.
This issue contains four excellent feature articles and a timely editorial by
Pierre Tattevin (APUA Board Chair):



 1. The continuing mission of APUA
    Pierre Tattevin

 2. Antifungal stewardship during COVID-19 times
    Sara F. Haddad, Souha S. Kanj and Jeroen Schouten

 3. Optimising patient outcomes through diagnostic stewardship
    Johnny Zakhour and Souha S. Kanj

 4. Beyond the pill: Transformative approaches to combat AMR
    Abdul Ghafur on behalf of AMR Declaration Trust / APUA

 5. The Global AMS Partnership Hub (GASPH)
    Dilip Nathwani

The newsletter also features the news on the latest activities by ISAC and APUA.
You can read the newsletter online and download it via the following e-reader:


READ / DOWNLOAD

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NEW ANTIBIOTIC SUMMARY CARDS

For the occasion of World AMR Awareness Week 2023, the Alliance for the Prudent
Use of Antibiotics (APUA) is proud to announce the launch of the second batch of
‘Antibiotic cards’ for a further six antibiotics currently in use with further
cards to follow. This project aims to provide a summary of the main
characteristics of selected antibiotics. These antibiotic cards have been
primarily designed to assist the prescribers in the selection of the most
appropriate antibiotic, with optimal dosages, and to provide guidance to those
who take care of patients who receive antibiotics.

These antibiotic cards have been produced by members of the APUA board and
colleagues, with no support from the pharmaceutical industry, and are available
free of charge. They share a common design, with a special focus on their
antimicrobial spectrum, main indications, dosing, and adverse events. We hope
that you will find them useful and that these antibiotic cards will contribute
to better use of antibiotics worldwide, the primary goal of APUA.


Download cards

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TACKLING AMR IN HOSPITAL SETTINGS

Join experts from around the globe, including Prof. Pierre Tattevin
(representing the Alliance for the Prudent Use of Antibiotics [APUA]) at this
free webinar organised by the Global Alliance for Infections in Surgery to
coincide with World AMR Awareness Week 2023 (WAAW).

📆21 November 2023


To give people from all over the world the opportunity to connect, the webinar
will last 15 hours, starting at 6.55 a.m. UTC and ending at 10.00 p.m. UTC.

register

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JUST PUBLISHED



Download the latest ISAC / APUA Newsletter which contains features articles, a
round-up of the latest AMR news as well as ISAC / APUA society news.

Volume 41, No. 2
Summer 2023

 1. Antibiotic access and use in the community setting in Africa and Asia:
    introducing the ABACUS projects
    Annelie L. Monnier and Heiman F. L. Wertheim on behalf of the ABACUS II
    consortium

 2. Prosthetic valve endocarditis following transcatheter aortic
    valve replacement: insights on microbiology, prophylaxis and treatment
    strategies
    Saliba Wehbe, Suha Kalash, Fatima Allaw, Johnny Zakhour and Souha S. Kanj

 3. 5th Global Ministerial Summit on Patient Safety 
    Pierre Tattevin

 4. Optimised doses of polymyxins to improve outcomes for non-critically ill and
    critically ill patients with MDR Gram-negative bacterial infection
    Puteri Zamri

Read newsletter

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AMR DECLARATION TRUST / APUA WEBINAR

We are delighted to invite you to a joint webinar by the AMR Declaration Trust
and the Alliance for the Prudent Use of Antibiotics (APUA):

"Beyond the pill: Transformative approaches to combat antimicrobial resistance"
26th August 2023
13.30 - 15.30 (CET) / 17:00 - 19:00 (IST)

We kindly request you distribute the attached flyer among your networks,
including members of the medical community, policymakers, industry professionals
and the public.

Please note there is no fee to register but registration is mandatory.




register

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AMR CONTROL UNDER ONE HEALTH

This plenary lecture was presented at the 32nd International Congress of
Antimicrobial Chemotherapy (ICC) in Perth, Australia.

Global leader Prof. Ramanan Laxminarayan presents an excellent plenary lecture
on understanding how antimicrobial resistance (AMR) should be managed in the One
Health context. The One Health concept recognises that the health of humans,
animals, plants and the environment are interconnected. Ramanan Laxminarayan is
the Founder and President of the One Health Trust founded as the Center for
Disease Dynamics, Economics & Policy (CDDEP).

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VIRAL RESPIRATORY TRACT INFECTIONS (RTIS): SUPERINFECTIONS



The Alliance for the Prudent Use of Antibiotics (APUA) hosted this recent
webinar on viral respiratory tract infections: superinfections.

Superinfection of viral respiratory infection has been one of the hottest topics
during the first waves of COVID-19: although it was rapidly demonstrated that
coinfections were rare during the first days, fungal or bacterial
superinfections was a major cause of death for intensive care unit patients on
various immunosuppressive treatments (dexamethasone, IL6-inhibitors, etc.), who
required prolonged mechanical ventilation. More recently, the burden of Group A
streptococci superinfections have dramatically increased, in children and in
adults, for reasons that still remain unclear.

Watch the on-demand recording to hear from three worldwide experts in the field
of superinfections who shared with us the main features of these hot topics.

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OPEN ACCESS ISAC / APUA ARTICLE

Diagnostic stewardship in infectious diseases: a continuum of antimicrobial
stewardship in the fight against antimicrobial resistance
Johnny Zakhour, Sara F Haddad, Anthony Kerbage, Wertheim Heiman, Pierre
Tattevin, Andreas Voss, Serhat Ünal, Abdoul Salam Ouedraogo, Souha S Kanj on
behalf of the International Society of Antimicrobial Chemotherapy (ISAC) and the
Alliance for the Prudent Use of Antibiotics (APUA)
Int J Antimicrob Agents. 2023 Apr 13;106816.

Abstract
Antimicrobial resistance (AMR) is an imminent threat to global health and has
been exacerbated by the inappropriate use of diagnostics that lead to excessive
prescription of antimicrobials. Diagnostic stewardship (DS) is an auxiliary to
antimicrobial stewardship (AMS) and emphasizes on ordering the right tests for
the right patient at the right time. It also promotes the judicious use of rapid
and novel molecular diagnostic tools to allow for initiation of proper
antibiotic therapy while avoiding excessive use of broad-spectrum antibiotics
when not needed. Proper interpretation of test results is crucial to avoid
overdiagnosis, and excessive healthcare costs. Although many rapid diagnostic
tools have been developed with a high diagnostic yield, they are often limited
by accessibility, cost, and lack of knowledge regarding their use. Careful
consideration of clinical signs and symptoms with knowledge of the local
epidemiology are cardinal for DS. This allows for appropriate interpretation of
microbiological results. Multidisciplinary teams that involve well trained
professionals should cooperate to promote DS. Challenges and barriers to the
implementation of DS are mostly caused by scarcity of resources and trained
personnel, and most importantly, lack of knowledge. The lack of resources is
often due to absence of awareness of the impact that good medical microbiology
diagnostic facilities and expertise can have on the proper use of antibiotics.

Read now

--------------------------------------------------------------------------------

The International Society of Antimicrobial Chemotherapy (ISAC) and the Alliance
for the Prudent Use of Antibiotics (APUA) are delighted to share the latest
issue of the ISAC / APUA Newsletter.

This issue contains four excellent feature articles:



 1. A new resistance combatting strategy
    Robin Patel

 2. Antimicrobial treatment of Pseudomonas aeruginosa severe sepsis
    Johnny Zakhour, Sima L. Sharara, Joya-Rita Hindy, Sara F. Haddad, Souha S.
    Kanj

 3. HAPPY PATIENT project: an update
    Carl Llor, Lars Bjerrum, Pierre Tattevin

 4. The ISAC Early Career Working Group: providing support to the next
    generation of researchers
    Jinxin Zhao, Yu-Wei Lin, Nusaibah Abdul Rahim, Iris Minichmayr

The newsletter also features a round-up of recent antimicrobial resistance and
stewardship news, as well as ISAC / APUA society updates.

Please email secretariat@isac.world with any suggestions for future articles.

If you are attending ECCMID, stop by the ISAC booth (booth #B3-07 1D) and pick
up a copy of the newsletter or find out more about ISAC / APUA and the 33rd
International Congress of Antimicrobial Chemotherapy (ICC).

read the newsletter

--------------------------------------------------------------------------------


ANTIBIOTIC CARDS

The Alliance for the Prudent Use of Antibiotics (APUA) is proud to announce the
launch of ‘Antibiotic cards’ for some of the main antibiotics currently in use
with further cards to follow. This project, initiated by Mushira Enani, aims to
provide a summary of the main characteristics of selected antibiotics. These
antibiotic cards have been primarily designed to assist the prescribers in the
selection of the most appropriate antibiotic, with optimal dosages, and to
provide guidance to those who take care of patients who receive antibiotics.

These antibiotic cards have been produced by members of the APUA board, with no
support from the pharmaceutical industry, and are available free of charge
through our website. They share a common design, with a special focus on their
antimicrobial spectrum, main indications, dosing, and adverse events. We hope
that you will find them useful and that these antibiotic cards will contribute
to better use of antibiotics worldwide, the primary goal of APUA.

View / Download the cards


--------------------------------------------------------------------------------




MICROBIAL THERANOSTICS - A RESISTANCE COMBATTING STRATEGY

Prof. Robin Patel presented the opening lecture at the 32nd International
Congress of Antimicrobial Chemotherapy (ICC) on "Microbial Theranostics - a
Resistance Combatting Strategy".
In this lecture, Prof. Patel presents a potential strategy to help in the fight
against the global antimicrobial resistance crisis through better diagnostics.
Subscribe to ISAC's YouTube Channel to watch other excellent plenary / keynote
lectures as they are uploaded.
Visit www.ISAC.world for more information about ISAC and how to join.

--------------------------------------------------------------------------------

"Antibiotics are uniquely societal drugs because individual use affects others
in the community and environment.  Better stewardship, incentives, and
establishment of a special regulatory category will improve how they are used,
marketed, and developed through incentives to industry."

Stuart B. Levy, M.D.
President of APUA, professor at Tufts University School of Medicine
From the IOM 25th Anniversary Symposium (1996) and The Antibiotic Paradox (2002)



 * Home/
 * About Us/
    * ISAC / APUA Merger
    * APUA Board
    * Individual membership
    * Organisational members
    * Join APUA
    * What We Do
    * Our History
    * APUA Publications
    * APUA / ISAC Reception
    * Contact Us

 * About the Issue/
    * General Background
    * Science of Resistance
    * Glossary

 * Policy/
    * APUA in Action
    * Antibiotic Use in Food Animals
    * Antibiotics and Nutrition
    * Other Initiatives
    * International Development

 * Research/
    * Research Competencies
    * Representative Projects

 * Resources/
    * Antibiotic cards
    * Antibiotic cards - vietnamese
    * Consumers
    * Educators
    * Practitioners
    * References

 * News/
    * APUA Newsletter
    * Latest APUA News
    * Antibiotic Resistance in the News
    * World Antibiotic Awareness Week
    * Tributes to Prof. Stuart Levy
    * APUA Webinars
    * In Memorium
    * APUA Leadership Award
    * Archives


ALLIANCE FOR THE PRUDENT USE OF ANTIBIOTICS

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Latest APUA Newsletters

ISAC/APUA Newsletter Spring 2024
ISAC/APUA Newsletter Winter 2023
ISAC / APUA Newsletter Summer 2023
ISAC / APUA Newsletter Spring 2023
ISAC / APUA Newsletter Winter 2022
ISAC / APUA Newsletter Spring 2022
ISAC / APUA Newsletter winter 2021
ISAC / APUA Newsletter Summer 2021

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