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THIS CONTENT WAS DESIGNED FOR PORTRAIT ORIENTATION ONLY. CME/MOC/NCPD/ILNA/IPCE Information Practice AidsSlidesPodcastsAbbr.ShareFeedback 1.5 CME/MOC/NCPD/ILNA/IPCEThis activity expired on May 25, 2025; credit is no longer available. Ten Steps for Highly Successful Myeloma Care: Guidance on the Road to Remission With Antibodies, BCMA Immunotherapy, and Other Innovations Please complete and tap Submit at the end to continue. Question 1/5 Which statement is true regarding the efficacy of isatuximab quadruplets (ie, adding isatuximab to carfilzomib or bortezomib-based platforms)? * Adding isatuximab was active but did not produce MRD-negative responses * Adding isatuximab did not improve activity compared with triplets * Adding isatuximab was active and produced MRD-negative responses * Isatuximab was active when combined with carfilzomib but not bortezomib platforms * I’m not sure Question 2/5 You are managing an older patient with RRMM who is preparing for therapy with the bispecific antibody teclistamab. Assuming that you have counseled the patient on dosing for the step-up period, how would you proceed when educating the patient on subsequent dosing aspects? * Note a 1.5 mg/kg weekly dose and the potential of every 2-week dosing based on response * Note a 0.3 mg/kg weekly dose and the potential of every 2-week dosing based on response * Educate the patient on continuous, 1.5 mg/kg weekly dosing * Note a 0.06 mg/kg weekly dose and use of every 2-week dosing based on response * I’m not sure Question 3/5 Think of a future scenario where you are managing a patient with RRMM on treatment with the novel BCMA x CD3 antibody linvoseltamab, first at the 200 mg IV weekly then biweekly schedule. If the patient achieves ≥VGPR after week 24, how would you address dosing considerations going forward? * Plan for a dose of 100 mg every 4 weeks * Suggest staying on the dose of 200 mg every 2 weeks * Plan for a dose of 200 mg every 4 weeks * Suggest reverting to a dose of 200 mg every week * I’m not sure Question 4/5 Consider a fit adult patient with RRMM and a PS of 1 with early progression after lenalidomide maintenance with VRd induction prior to ASCT. Assuming this patient is willing to pursue aggressive treatment, how would you plan for the next steps in care while working with your colleagues on the healthcare team? * Plan for CAR-T with no bridging * Plan for treatment with a CD38-based regimen (no CAR-T) * Plan for the use of an alternative lenalidomide-based treatment * Plan for CAR-T, bridge with Dara-Pd, then refer to CAR-T * I’m not sure Question 5/5 Assume that you are developing a safety care plan for a patient with NDMM preparing to receive a CD38 antibody platform. How would you plan to mitigate hypersensitivity reactions? * Plan for steroid premedication prior to therapy * Plan for premedication with acetaminophen and diphenhydramine * Plan for premedication with acetaminophen, diphenhydramine, and steroids * Plan for optional premedication with acetaminophen, diphenhydramine, and steroids * I’m not sure Submit CHAIR & MODERATOR Beth Faiman, PhD, MSN, APN-BC, AOCN, BMTCN, FAAN, FAPO Cleveland Clinic Taussig Cancer Institute Department of Hematology and Medical Oncology Member, Population and Cancer Prevention Program Case Comprehensive Cancer Center Cleveland, Ohio PRESENTER Donna D. Catamero, ANP-BC, OCN, CCRC Associate Director, Myeloma Research The Mount Sinai Health System New York, New York PRESENTER Charise Gleason, MSN, NP-C, AOCNP Vice President and Chief Advanced Practice Officer Emory Healthcare Atlanta, Georgia In support of improving patient care, this activity has been planned and implemented by PVI, PeerView Institute for Medical Education, and HealthTree Foundation for Multiple Myeloma. PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team. Support This activity is supported by educational grants from Bristol Myers Squibb, Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC, Regeneron Pharmaceuticals, Inc., and Sanofi. Physicians PVI, PeerView Institute for Medical Education, designates this enduring material for a maximum of 1.5 AMA PRA Category 1 CreditsTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity. MOC Statement Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1.5 MOC points and patient safety MOC credit in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit. Participation information will be shared through the ACCME’s Program and Activity Reporting System (PARS). Through an agreement between the Accreditation Council for Continuing Medical Education and the Royal College of Physicians and Surgeons of Canada, medical practitioners participating in the Royal College MOC Program may record completion of accredited activities registered under the ACCME’s “CME in Support of MOC” program in Section 3 of the Royal College’s MOC Program. Nurses Successful completion of this nursing continuing professional education activity will be awarded 1.5 contact hour(s) and 1.50 contact hour(s) in the area of pharmacology. ILNA Coding Statement The program content has been reviewed by the Oncology Nursing Certification Corporation (ONCC) and is acceptable for recertification points as follows: 1.5 points: Care Continuum, Nursing Practice, Professional Practice/Performance, Psychosocial Dimension of Care, Roles of the APRN, Symptom Management, Palliative Care, Supportive Care, Treatment The numerical value(s) indicated above is the maximum amount of points that can be claimed in each subject area domain. The total amount of points claimed may not exceed the total amount of nursing continuing professional development (NCPD) or CME awarded from this course and may only apply to the credential being renewed. Interprofessional Continuing Education (IPCE) Statement This activity was planned by and for the healthcare team, and learners will receive 1.5 Interprofessional Continuing Education (IPCE) credits for learning and change. Disclosure Policy PVI, PeerView Institute for Medical Education, disclosure policy adheres to The Standards for Integrity and Independence in Accredited Continuing Education. All individuals in a position to control the content of a CE activity, including faculty, planners and reviewers are required to disclose all financial relationships with ineligible companies (commercial interests) that as an entity produces, markets, re-sells or distributes healthcare goods or services consumed by or used on patients. All relevant conflicts of interest have been mitigated prior to the commencement of the activity. Faculty/Planner Disclosures Chair/Planner Beth Faiman, PhD, MSN, APN-BC, AOCN, BMTCN, FAAN, FAPO, has a financial interest/relationship or affiliation in the form of: Consultant and/or Advisor for Bristol Myers Squibb; GlaxoSmithKline; Janssen Pharmaceuticals, Inc.; Karyopharm Therapeutics; Pfizer; and Sanofi. Faculty/Planner Donna D. Catamero, ANP-BC, OCN, CCRC, has a financial interest/relationship or affiliation in the form of: Consultant and/or Advisor for Bristol Myers Squibb; Janssen Pharmaceuticals, Inc.; Karyopharm Therapeutics; and Pfizer. Speaker for Bristol Myers Squibb and Janssen Pharmaceuticals, Inc. Faculty/Planner Charise Gleason, MSN, NP-C, AOCNP, has a financial interest/relationship or affiliation in the form of: Consultant and/or Advisor for Pfizer. Planning Committee and Reviewer Disclosures Planners, independent reviewers, and staff of PVI, PeerView Institute for Medical Education, do not have any relevant financial relationships related to this CE activity unless listed below. CONNECT WITH US Copyright © 2000-2024, PeerView Terms of Use | Privacy Policy | Sign Up for Email Alerts This site uses cookies.Learn More. ×