cytel.com Open in urlscan Pro
5.100.156.151  Public Scan

Submitted URL: https://url.us.m.mimecastprotect.com/s/WUGnCYExEKux34WjHDuGFxjI1Z?domain=9zy04.na1.hubspotlinks.com
Effective URL: https://cytel.com/news-and-events/cytel-launches-east-horizon/?utm_campaign=2024_Partner%20Program%20newsletter&ut...
Submission: On October 02 via manual from US — Scanned from US

Form analysis 5 forms found in the DOM

GET https://cytel.com/

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GET https://cytel.com/

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   Data Strategy
   Model-lnformed Drug Development
   Chemistry, Manufacturing and Controls (CMC)
   Toxicology Solutions
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   We help you navigate complex trial phases efficiently with data-driven
   methods & strategies tailored to Phase I-III trials for accelerated drug
   development.
   
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   Adaptive Trial Designs
   Complex and Innovative Trial Design
   Model-lnformed Drug Development
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   insights and shape future drug development cycles for enhanced efficacy and
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   Real-World Evidence
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   Post-Authorization Safety Studies
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   Clinical Trial Design
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   Craft optimal trial designs with our advanced analytical methods to enhance
   efficiency and increase the probability of success throughout your drug’s
   lifecycle.
   
   Learn more
   
   QUICK LINKS
   
   Adaptive Trial Design
   Complex and Innovative Trial design
   Model-lnformed Drug Development
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   Empower your trial delivery by transforming trial designs into actionable
   strategies with our data-driven approach to ensure seamless delivery and
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   Unlock the power of data with our methods for actionable insights to drive
   informed decisions and optimize clinical trial outcomes.
   
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   Complex and Innovative Trial Design
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   We offer tailored analytics solutions for your specialized or niche projects
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   External Controls
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   Post-Authorization Safety Studies
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   Pediatrics
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Home News & events Cytel Launches East Horizon™ Platform: Advancing the Science
of Adaptive Clinical Trial Design and Simulation


CYTEL LAUNCHES EAST HORIZON™ PLATFORM: ADVANCING THE SCIENCE OF ADAPTIVE
CLINICAL TRIAL DESIGN AND SIMULATION


September 30, 2024

CYTEL

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New platform integrates East® software’s established adaptive design workflows
with cutting-edge cloud computing simulation and advanced design capabilities
for enhanced clinical development.

Cambridge, MA. – September 30, 2024 – Cytel, a leader in statistical software
and advanced quantitative solutions for clinical research, announces the release
of East Horizon™, an innovative platform that represents a significant
advancement in the field of clinical trial design and simulation. Building on
the foundation of Cytel’s industry-standard East® software, the East Horizon
trial design platform is a collaborative workbench for biostatisticians to
create and optimize trials to help maximize probability of success and reduce
the time to market for life-saving medicines. This platform consolidates Cytel’s
best-in-class assets in a single synergistic workflow, integrating advanced
open-source capabilities and analytics tools in a single, easy to access cloud
platform.

“For over three decades, East software has been pivotal in shaping robust and
scientifically sound clinical trials,” said Kevin Trimm, Chief Product Officer
at Cytel. “East Horizon extends this legacy by incorporating state-of-the-art
design capabilities, simulation-based approaches, and cloud-powered computing,
providing researchers and statisticians with a unified platform for trial design
and decision-making.”

 


COMPREHENSIVE MODULES TO ADDRESS THE COMPLEXITIES OF CLINICAL TRIAL DESIGN

The East Horizon™ platform introduces a range of specialized modules to support
clinical trials across all stages of development, addressing both the
statistical rigor and operational complexities required in modern clinical
research:

 * Early Phase Designs
   * Dose Escalation Module: Optimizes dose escalation strategies for Phase I
     studies.
   * Dose Finding Module: Determines optimal dosing in early-stage trials using
     both Frequentist and Bayesian approaches.

 * Late Phase Designs
   * Fixed Sample and Group Sequential Modules: Facilitates both fixed-sample
     and group sequential designs, allowing researchers to apply both
     Frequentist and Bayesian methodologies.
   * Multiplicity and Adaptive Modules: Manages multiplicity issues and supports
     adaptive designs in later phases of development.

 


R-INTEGRATION CAPABILITIES AND AI-DRIVEN CODING ASSISTANCE

The East Horizon™ platform’s native designs can be easily extended by the user
in an infinite number of ways using R code integration points throughout the
software. Users can leverage

Cytel’s CyneRgy R package, a comprehensive library of code samples and
documentation, or employ their own R scripts.

 


IMPLICATIONS FOR CLINICAL RESEARCH AND DEVELOPMENT

The East Horizon™ platform is set to transform clinical trial design and
execution by enabling rapid, precise modeling, simulation, and optimization of
study protocols. Its integration of AI and cloud computing with established
statistical tools provides a robust environment for adaptive design and
real-time scenario evaluation.

“Cytel has always been a proponent of innovation and collaboration.”, said Jovan
Willford, CEO at Cytel. “We believe that we are in a position to help ensure
that innovation, regardless of where it occurs, rapidly reaches the statistical
market. East Horizon provides a transparent, validated, platform for the
storage, sharing and collaboration of open-source R code. This will be an
important cornerstone of our software strategy — bringing together the best
open-source and proprietary workflow tools.”

“I am delighted by Cytel’s latest advancement in adaptive trial design
software,” said Marisa Bacchi, PhD, Senior Statistical Advisor with over two
decades of experience in the biotech and pharmaceutical industry. “Cytel’s
software has always excelled at fostering collaboration among cross-functional
drug development teams. The integration of their legacy and cutting-edge
solutions into a single AI-driven platform will undoubtedly enhance evidence
generation and decision-making in drug development and lead to improved
solutions for the benefit of patients.”


ABOUT CYTEL

Cytel is the world’s leading provider of statistical software, advanced
quantitative solutions, and statistical methods for the life sciences industry,
committed to advancing human health. For nearly four decades, Cytel has set the
standard in adaptive trial design, using data-driven insights to inform strategy
across all phases of drug development and commercialization. By accelerating
drug development, improving success rates, and delivering better patient
outcomes, Cytel continues to drive innovation in clinical research.

For more information about the East Horizon platform or to request a
comprehensive overview of its capabilities, please visit
cytel.com/east-horizon/or contact support@cytel.com

 

East Horizon™ and East® are trademarks or registered trademarks of Cytel Inc.
All rights reserved.

Media Contact:
Sofie Vandevyver
VP, Global Head of Marketing
sofie.vandevyver@cytel.com

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DRUG DEVELOPMENT CYCLE

Pre-Clinical / Discovery Phase I-III Clinical Trials Commercialization
Real-World Evidence Solutions

STRATEGIC ANALYTICS

Clinical Trial Design Trial Delivery Advanced Analytics Specialty Areas

DELIVERY MODELS

Strategic Consulting Beyond Functional Service Provider Project-Based Solutions

SOFTWARE SOLUTIONS

Trial Design Software Live SLR® Trial Implementation and Decision Support
Software

THERAPEUTIC AREAS

Rare Disease Oncology Other Therapeutic Areas

ABOUT US

Our Experts Innovation Advisory Board Leadership Team Board of Directors
Sustainability

INSIGHTS

Perspectives News & Events Resources Publications Cytel Design Institute

CAREERS

Connect With Us Join Our Talent Network

CONTACT US

Phone:
+1 (617) 661-2011

Email:
support@cytel.com

675 Massachusetts Ave Cambridge, MA 02139 USA

DRUG DEVELOPMENT CYCLE

Pre-Clinical / Discovery Phase I-III Clinical Trials Commercialization
Real-World Evidence Solutions

STRATEGIC ANALYTICS

Clinical Trial Design Trial Delivery Advanced Analytics Specialty Areas

DELIVERY MODELS

Strategic Consulting Beyond Functional Service Provider Project-Based Solutions

SOFTWARE SOLUTIONS

Trial Design Software Live SLR® Trial Implementation and Decision Support
Software

THERAPEUTIC AREAS

Rare Disease Oncology Other Therapeutic Areas

ABOUT US

Our Experts Innovation Advisory Board Leadership Team Board of Directors
Sustainability

INSIGHTS

Perspectives News & Events Resources Publications Cytel Design Institute

CAREERS

Connect With Us Join Our Talent Network

CONTACT US

Phone:
+1 (617) 661-2011

Email:
support@cytel.com

675 Massachusetts Ave Cambridge, MA 02139 USA

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