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 1. Healio
 2. CME
 3. Cardiology

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INDIVIDUALIZING CARE FOR HIGH-RISK PATIENTS WITH HFREF FOLLOWING DECOMPENSATION
EVENTS

Release 9/20/2022; Expiration 9/20/2023

1.00 CME
1.00 AAPA
60 MINS
$0 FEE
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ACTIVITY OVERVIEW

Heart failure with reduced ejection fraction (HFrEF) is a global health
challenge that poses a significant burden on the healthcare system and on
patients’ quality of life. In recent years, new pathways for improving cardiac
function have been targeted by novel pharmaceuticals as well as by advanced
cardiac devices, with particular emphasis on high-risk patients with HFrEF.
However, challenges still exist in translating prognostic data regarding
high-risk patient populations with HFrEF into therapeutic action in clinical
practice. This adaptive learning activity will personalize and customize your
learning experience as you acquire and apply knowledge about managing patients
with HFrEF that is consistent with the new guidelines for heart failure.

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TARGET AUDIENCE

This activity is intended Cardiologists, Primary Care Physicians, PAs, Nurses,
and other healthcare providers who diagnose and manage patients with HFrEF.

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LEARNING OBJECTIVES

Upon completion of the educational activity, participants should be able to:

 * Evaluate risk in patients with HFrEF to identify populations at high risk for
   death and hospitalization for heart failure.
 * Identify treatment options for patients with HFrEF following hospitalization
   for heart failure or need for outpatient intravenous diuretics.
 * Design an individualized treatment regimen for high-risk patients with HFrEF
   following decompensation events, incorporating appropriate patient selection,
   drug combinations, and dose escalations as needed.

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CRITERIA FOR SUCCESS

To obtain a certificate of completion, a score of 100 % proficiency is required.
Please proceed with the activity until you have successfully completed this
program, answered all test questions, completed the evaluation, and have
received a digital copy of your certificate. You must participate in the entire
activity to receive credit. There is no fee to participate in this activity. If
you have questions about this activity, please contact AKH Inc. at
byron@akhcme.com.

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FACULTY



Barry H. Greenberg, MD
Distinguished Professor of Medicine
Director, Advanced Heart Failure Treatment Program
UCSD Medical Center

Barry H. Greenberg, MD, is Distinguished Professor of Medicine and Director of
the Advanced Heart Failure Treatment Program at the University of California,
San Diego (UCSD). He earned a medical degree from the State University of New
York Upstate Medical University College of Medicine in Syracuse and completed
his internship at George Washington University Hospital and residency in
internal medicine at Yale-New Haven Hospital. Following research training at the
Lipid Metabolism Branch of the National Heart, Lung, and Blood Institute in
Bethesda, Maryland and the Cardiovascular Research Institute of the University
of California, San Francisco (UCSF), he completed a fellowship in cardiology at
UCSF. He then joined the faculty of Oregon Health Sciences University School of
Medicine. Prior to arriving at UCSD, he was visiting professor in residence at
the Royal Postgraduate Medical School in London, England and at the Laboratoire
de Médicine Expérimentale of the Collège de France in Paris.

Dr. Greenberg’s clinical research focuses on understanding mechanisms of cardiac
dysfunction and developing new heart failure therapies. He has served on the
executive steering committees of numerous international multicenter heart
failure trials including most recently RELAX-AHF2, RELAX-AHF Asia, COMMANDER-HF
(co-chair) and DREAM-HF (co-chair) and he currently chairs a number of DSMB
committees for clinical trials. In addition, Dr. Greenberg directs a basic
science laboratory that studies the molecular basis of cardiac remodeling,
myocardial fibrosis and the development of novel therapies. His recent clinical
research activities have focused on the use of artificial intelligence to
develop algorithms for predicting risk of clinical events in patients with heart
failure and other cardiovascular diseases. Dr. Greenberg has published
extensively in top-tiered medical journals throughout his career.

Dr. Greenberg is co-editor of Congestive Heart Failure: Pathophysiology,
Diagnosis, and Comprehensive Approach to Management, the first comprehensive
text in this field, now in its 3rd edition and is editor of Myocardial
Remodeling: Mechanisms and Treatment, published in 2006 and Management of Heart
Failure published in 2010. He served as Associate Editor for the Journal of the
American College of Cardiology (JACC) from 2002-2014 and is a senior member of
the editorial boards of several cardiology and subspecialty journals including
European Journal of Heart Failure. He is currently Guest Editor-in-Chief of
JACC:HF.

Dr. Greenberg is a founding member and past President of the Heart Failure
Society of America (HFSA). He chaired the initial HFSA Heart Failure Board
Review Course and he has served as Chair for numerous HFSA Committees (including
Education, Advocacy, Nominating, and Corporate Affairs), the Strategic
Development initiative in 2010 and the Journal of Cardiac Failure Task Force in
2020.

Dr. Greenberg has been selected for many years as one of the “Best Doctors in
America” and “Best Doctors in San Diego.” In recognition of accomplishments over
the course of his career Dr. Greenberg received the HFSA’s Lifetime Achievement
Award in 2017.



Yasmine S. Ali, MD, MSCI, FACC, FACP is a board-certified cardiologist and
clinical lipidologist who has focused her clinical career on the promotion of
heart health and the prevention of cardiovascular disease. She is a prolific
medical writer and educator, and is President of LastSky Writing, LLC. In
addition to her clinical experience as a cardiologist, she has 25 years of
medical writing experience, much of it in the CME space.

Dr. Ali has served as Chief Editor of the Atherosclerosis & Risk Factors section
of Medscape Reference Drugs and Diseases (from WebMD) for over a decade. She has
numerous peer-reviewed publications focused on mechanisms of atherosclerosis and
the detection and treatment of ASCVD. She is Assistant Clinical Professor of
Medicine at Vanderbilt University School of Medicine. Dr. Ali is also a Fellow
of the American College of Cardiology (FACC), a Premium Professional Member of
the American Heart Association, and a Fellow of the American College of
Physicians (FACP). 
Dr. Ali is also an award-winning writer and essayist, and is the author of Walk
Through Fire: The Train Disaster That Changed America (March 2023), which
highlights the irreplaceable role of the community hospital in US history.

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CE credit provided by AKH Inc., Advancing Knowledge in Healthcare.

In support of improving patient care, this activity has been planned and
implemented by AKH Inc., Advancing Knowledge in Healthcare. AKH Inc., Advancing
Knowledge in Healthcare is jointly accredited by the Accreditation Council for
Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy
Education (ACPE), and the American Nurses Credentialing Center (ANCC), to
provide continuing education for the healthcare team.

Physicians
AKH Inc., Advancing Knowledge in Healthcare designates this enduring material
activity for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should
claim only the credit commensurate with the extent of their participation in the
activity.

Nurses
Credit being awarded: 1.0 ANCC contact hours.

Physician Assistant
AKH Inc., Advancing Knowledge in Healthcare has been authorized by the American
Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned
in accordance with AAPA CME Criteria. This activity is designated for 1.0 AAPA
Category 1 CME credits. Approval is valid until 9/20/2023. PAs should only claim
credit commensurate with the extent of their participation.

--------------------------------------------------------------------------------


COMMERCIAL SUPPORT

This activity is supported from an independent medical education grant from
Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc.

--------------------------------------------------------------------------------

DISCLOSURES

Name

Relationship

Commercial Interest

Barry Greenberg, MD (Course Chair)

Consultant

ACI, Actelion, Axon, AstraZeneca, Boehringer Ingelheim, Bayer, Cytokinetics, EBR
systems, Faraday, Impulse Dynamics, Inventiva, Ionis, Jaan, Merck, Salubris,
Vifor, Viking Windtree

 

Speaker

Novartis

Researcher

Rocket Pharmaceuticals

Yasmine Ali, MD, MSCI, FACC, FACP (faculty)

Consultant

Philips Healthcare

Dorothy Caputo, MA, BSN, RN, Senior Director of Continuing Education &
Compliance

N/A

Nothing to disclose

Michele Bielarski, RN, AKH Nurse Review

N/A

Nothing to disclose

AKH Inc Staff and Planners

N/A

Nothing to disclose

Area9 Staff and Planners

N/A

Nothing to disclose

All of the relevant financial relationships listed for these individuals have
been mitigated.


DISCLOSURE

It is the policy of AKH Inc. to ensure independence, balance, objectivity,
scientific rigor, and integrity in all of its continuing education activities.
The author must disclose to the participants any significant relationships with
ineligible companies whose products or devices may be mentioned in the activity
or with the commercial supporter of this continuing education activity.
Identified conflicts of interest are mitigated by AKH prior to accreditation of
the activity. AKH planners and reviewers have no relevant financial
relationships to disclose.

--------------------------------------------------------------------------------


DISCLOSURE OF UNLABELED USE AND INVESTIGATIONAL PRODUCT

This educational activity may include discussion of uses of agents that are
investigational and/or unapproved by the FDA. Please refer to the official
prescribing information for each product for discussion of approved indications,
contraindications, and warnings.

--------------------------------------------------------------------------------


DISCLAIMER

This course is designed solely to provide the healthcare professional with
information to assist in his/her practice and professional development and is
not to be considered a diagnostic tool to replace professional advice or
treatment. The course serves as a general guide to the healthcare professional,
and therefore, cannot be considered as giving legal, nursing, medical, or other
professional advice in specific cases. AKH Inc. specifically disclaim
responsibility for any adverse consequences resulting directly or indirectly
from information in the course, for undetected error, or through participant's
misunderstanding of the content.

--------------------------------------------------------------------------------


REQUIRED HARDWARE/SOFTWARE:

A computer with an internet connection
Internet Browser: Internet Explorer 7.x or higher, Firefox 4.x or higher, Safari
2.x or higher, or any other W3C standards compliant browser
Other additional software may be required such as PowerPoint or Adobe Acrobat
Reader

AKH Privacy Policy (link: https://akhcme.com/akhcme/pages/privacy)

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