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   Spinal Muscular Atrophy
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   HIV
   Narcolepsy
   Nephrology
   Psoriasis
   Psoriatic Arthritis
   Rheumatoid Arthritis
 * Research Reviews
   Clinical Advances
   Comparative Effectiveness
   HEOR
   Real-World Outcomes
 * Rheumatology Insights
   Ankylosing Spondylitis
   Nonradiographic Axial Spondyloarthritis
   Psoriasis
   Psoriatic Arthritis
 * LTACH Insights




PSORIASIS TOPIC CENTER

FEATURED ARTICLE

News
Before Secukinumab Treatment, Prescreening for Inflammatory Bowel Disease
Advised
10/12/2021
Jolynn Tumolo
“Given the utilization of secukinumab as a therapy for psoriasis and psoriatic
arthritis, appropriate screening and risk stratification could help limit
morbidity and mortality that can be associated with secukinumab-induced
inflammatory bowel disease,” researchers advised. 
10/12/2021
First Report Managed Care

News
Analysis Shows High Rates of Patient Satisfaction With Secukinumab for Plaque
Psoriasis
09/15/2021
Jolynn Tumolo
“In this analysis of deidentified electronic medical record data from patients
with predominantly moderate-to-severe plaque psoriasis, patients achieved and
maintained a high level of treatment satisfaction with secukinumab up to 24
months, regardless of previous treatment experience,” researchers wrote.
09/15/2021
First Report Managed Care

News
Prescriptions Drive Higher Costs for Moderate-to-Severe Pediatric Psoriasis
08/17/2021
Jolynn Tumolo
“Higher unadjusted health care costs by severity were driven by outpatient
prescription costs,” researchers reported.
08/17/2021
First Report Managed Care

Videos
Psoriasis Treatment Effective at Achieving Skin Clearance
07/26/2021
Maria Asimopoulos
Jeffrey Stark, MD, head of immunology medical affairs, UCB, breaks down the
unique challenges patients with psoriasis face, and discusses the BE RADIANT and
BE SURE studies, both of which indicated that bimekizumab was effective at
achieving skin clearance in this patient population.
07/26/2021
First Report Managed Care

News
Improvements in Psoriasis Skin Severity Related to Sustained Gains in QoL
06/18/2021
Jolynn Tumolo
“Patients who experience improvements in skin severity are likely to also
experience improvements in quality of life,” researchers wrote. “Similarly, once
skin severity no longer improves, quality of life is likely to remain stable."
06/18/2021
First Report Managed Care

News
Medicare Part D Spending for Psoriasis Drugs Grows
06/07/2021
Jolynn Tumolo
“Psoriasis prescriptions comprise a large, increasing proportion of Medicare
Part D spending related to dermatology,” researchers wrote. “These increasing
costs have significant implications for the health care system and affect
out-of-pocket costs for patients who rely on such medications.”
06/07/2021
First Report Managed Care

News
No Link Between Psoriasis and Non-Ischemic Dilated Cardiomyopathy
06/01/2021
Jolynn Tumolo
Despite case reports and small observational studies that have suggested a link
between psoriasis and non-ischemic dilated cardiomyopathy, a new
population-based cross-sectional study failed to find such an association.
06/01/2021
First Report Managed Care

News
For Inflammatory Joint and Skin Disease, Switching More Common With Oral Than
Injectable Immunotherapy
12/07/2020

“Health care resource utilization was higher in the oral group, but total costs
were lower,” researchers reported, “which was likely driven by the lower costs
of oral drugs.” 
12/07/2020
First Report Managed Care

News
Treatment Class May Worsen Fungal Infections in Patients With Psoriasis
10/31/2020

The paper focused on Candida infections in patients with psoriasis and psoriatic
arthritis treated with interleukin-17 (IL-17) inhibitors.
10/31/2020
First Report Managed Care

News
Major QoL Impairment Possible Among Patients With Lower PASI Scores
10/07/2020

Although the minimum eligibility for psoriasis treatment is typically a PASI
score of 10 or 12, which is considered moderate psoriasis, patients with lower
scores can still have major quality of life impairment.
10/07/2020
First Report Managed Care

News
Psoriasis Associated With High Level of Comedication
09/17/2020

“Comorbidity highly influences the total morbidity, health care costs, and
socioeconomic burden of psoriasis. It has been estimated that a third of
productivity losses in psoriasis patients are attributed to psoriasis while
comorbidity accounts for the rest,” researchers wrote. 
09/17/2020
First Report Managed Care

NEWSFEED

News
Before Secukinumab Treatment, Prescreening for Inflammatory Bowel Disease
Advised
10/12/2021
Jolynn Tumolo
“Given the utilization of secukinumab as a therapy for psoriasis and psoriatic
arthritis, appropriate screening and risk stratification could help limit
morbidity and mortality that can be associated with secukinumab-induced
inflammatory bowel disease,” researchers advised. 
10/12/2021
First Report Managed Care
News
Analysis Shows High Rates of Patient Satisfaction With Secukinumab for Plaque
Psoriasis
09/15/2021
Jolynn Tumolo
“In this analysis of deidentified electronic medical record data from patients
with predominantly moderate-to-severe plaque psoriasis, patients achieved and
maintained a high level of treatment satisfaction with secukinumab up to 24
months, regardless of previous treatment experience,” researchers wrote.
09/15/2021
First Report Managed Care
News
Prescriptions Drive Higher Costs for Moderate-to-Severe Pediatric Psoriasis
08/17/2021
Jolynn Tumolo
“Higher unadjusted health care costs by severity were driven by outpatient
prescription costs,” researchers reported.
08/17/2021
First Report Managed Care
News
Improvements in Psoriasis Skin Severity Related to Sustained Gains in QoL
06/18/2021
Jolynn Tumolo
“Patients who experience improvements in skin severity are likely to also
experience improvements in quality of life,” researchers wrote. “Similarly, once
skin severity no longer improves, quality of life is likely to remain stable."
06/18/2021
First Report Managed Care
News
Medicare Part D Spending for Psoriasis Drugs Grows
06/07/2021
Jolynn Tumolo
“Psoriasis prescriptions comprise a large, increasing proportion of Medicare
Part D spending related to dermatology,” researchers wrote. “These increasing
costs have significant implications for the health care system and affect
out-of-pocket costs for patients who rely on such medications.”
06/07/2021
First Report Managed Care
News
No Link Between Psoriasis and Non-Ischemic Dilated Cardiomyopathy
06/01/2021
Jolynn Tumolo
Despite case reports and small observational studies that have suggested a link
between psoriasis and non-ischemic dilated cardiomyopathy, a new
population-based cross-sectional study failed to find such an association.
06/01/2021
First Report Managed Care
News
For Inflammatory Joint and Skin Disease, Switching More Common With Oral Than
Injectable Immunotherapy
12/07/2020

“Health care resource utilization was higher in the oral group, but total costs
were lower,” researchers reported, “which was likely driven by the lower costs
of oral drugs.” 
12/07/2020
First Report Managed Care
News
Treatment Class May Worsen Fungal Infections in Patients With Psoriasis
10/31/2020

The paper focused on Candida infections in patients with psoriasis and psoriatic
arthritis treated with interleukin-17 (IL-17) inhibitors.
10/31/2020
First Report Managed Care
News
Major QoL Impairment Possible Among Patients With Lower PASI Scores
10/07/2020

Although the minimum eligibility for psoriasis treatment is typically a PASI
score of 10 or 12, which is considered moderate psoriasis, patients with lower
scores can still have major quality of life impairment.
10/07/2020
First Report Managed Care
News
Psoriasis Associated With High Level of Comedication
09/17/2020

“Comorbidity highly influences the total morbidity, health care costs, and
socioeconomic burden of psoriasis. It has been estimated that a third of
productivity losses in psoriasis patients are attributed to psoriasis while
comorbidity accounts for the rest,” researchers wrote. 
09/17/2020
First Report Managed Care
News
Meta-analysis Finds Predictors of Psoriatic Arthritis in Patients With Psoriasis
10/12/2021
Jolynn Tumolo
“Identifying predictors and risk factors for the development of psoriatic
arthritis among psoriasis patients is a crucial step for the understanding of
the pathophysiology of psoriatic arthritis and for the recognition of psoriasis
patients that could benefit from psoriatic arthritis interception or early
intervention near to psoriatic arthritis onset,” researchers wrote.
10/12/2021
First Report Managed Care
News
Before Secukinumab Treatment, Prescreening for Inflammatory Bowel Disease
Advised
10/12/2021
Jolynn Tumolo
“Given the utilization of secukinumab as a therapy for psoriasis and psoriatic
arthritis, appropriate screening and risk stratification could help limit
morbidity and mortality that can be associated with secukinumab-induced
inflammatory bowel disease,” researchers advised. 
10/12/2021
First Report Managed Care
News
Most Group Practices Achieve Exceptional Performance for MIPs Year 2
10/12/2021
Jolynn Tumolo
“The findings of this cross-sectional study suggest that despite more stringent
composite score thresholds for 2020 payment adjustments, most practices achieved
exceptional performance,” authors wrote.
10/12/2021
First Report Managed Care
News
The Public Backs Medicare Rx Price Negotiation Even After Hearing Both Sides’
Views
10/12/2021

Amanda Michelle Gomez, Kaiser Health News

Amanda Michelle Gomez, Kaiser Health ...
Recent poll results revealed that the majority of Americans support the federal
government negotiating lower drug prices for beneficiaries of both Medicare and
private insurance, despite the pharmaceutical industry's argument that current
prices help fund research.
10/12/2021
First Report Managed Care
News
Treatment Reduces Appetite, Weight in Patients With Obesity
10/08/2021
Maria Asimopoulos
Patients with obesity experienced greater reductions in appetite, food
consumption, and body weight while receiving once-weekly subcutaneous
semaglutide 2.4 mg in comparison to placebo.
10/08/2021
First Report Managed Care
News
Integrated HIV, Diabetes, and Hypertension Services Cut Costs for Providers,
Patients
10/07/2021
Jolynn Tumolo
“In this cohort study, we have demonstrated that one-stop treatment of
comorbidities is likely worthwhile and an efficient strategy enhancing financial
equity in service provision for people with multiple conditions in sub-Saharan
Africa settings,” researchers wrote.
10/07/2021
First Report Managed Care
News
Analysis Finds Sharp Increase in Concentration of Spending on Prescription Drugs
10/07/2021
Jolynn Tumolo
“In 2001, one-half of all expenditures on prescription drugs were concentrated
in 6.0% of the US population,” researchers wrote, “but by 2018, this proportion
had decreased to 2.3%.”
10/07/2021
First Report Managed Care
News
Black Patients Report More Out-of-Pocket Costs for Atopic Dermatitis
10/06/2021
Jolynn Tumolo
“Additional studies are needed to better understand unique out-of-pocket
financial considerations among Black individuals and develop targeted approaches
to reduce both the financial and overall burden of atopic dermatitis,” concluded
researchers.
10/06/2021
First Report Managed Care
News
Congress Debates Medicaid Expansion, Coverage Gaps
09/30/2021

Phil Galewitz, Kaiser Health News

Phil Galewitz, Kaiser Health News ...
Congressional Democrats are moving to close the coverage gap after 12 states
have not expanded Medicaid, but their efforts have yielded concerns about costs.
09/30/2021
First Report Managed Care
News
Study Finds Inverse Correlation Between Endothelial Function and Depression in
PsA
09/30/2021
Jolynn Tumolo
“If validated in longitudinal studies, this evidence would encourage a
systematic research of depressive symptoms as a part of a correct assessment of
cardiovascular risk in PsA,” researchers wrote, “helping to raise the
effectiveness of prevention strategies.”
09/30/2021
First Report Managed Care

INSIGHTS

Videos
Psoriasis Treatment Effective at Achieving Skin Clearance
07/26/2021
Maria Asimopoulos
Jeffrey Stark, MD, head of immunology medical affairs, UCB, breaks down the
unique challenges patients with psoriasis face, and discusses the BE RADIANT and
BE SURE studies, both of which indicated that bimekizumab was effective at
achieving skin clearance in this patient population.
07/26/2021
First Report Managed Care
Interviews
Psoriatic Arthritis: A Dermatologist’s Perspective
08/01/2019

Alice B. Gottlieb, MD, PhD, clinical professor of dermatology at the Icahn
School of Medicine at Mount Sinai in New York, discusses the importance of early
identification for patients with psoriatic arthritis as well as treatments that
are currently available.
08/01/2019
First Report Managed Care
Commentary
Insights Into Selecting Biologics for Psoriasis
07/08/2019

Lawrence Green, MD, associate clinical professor of dermatology at George
Washington University School of Medicine, reviews current biologic therapies
available for psoriasis and shares his methods for selecting the appropriate
biologic for patients.
07/08/2019
First Report Managed Care
Interviews
Inside the New Psoriasis Guidelines, Part I
05/09/2019

Alan Menter, MD, chairman of the division of dermatology at Baylor University
Medical Center, Dallas, TX, and Craig A. Elmets, MD, professor of dermatology at
the University of Alabama in Birmingham and co-chair of the guideline workgroup,
provide a deeper dive into the recent updates that address the latest evidence
on the safety and efficacy of biologics.
05/09/2019
First Report Managed Care
Interviews
Reviewing the Recently Released Psoriasis Guidelines
03/14/2019

In this discussion, Jeffery Weinberg, MD, medical dermatologist at Mount Sinai
School of Medicine, and Megan Noe, MD, MPH, dermatologist at the University of
Pennsylvania, highlight the new psoriasis treatment guidelines released by NPF
and AAD and they explain why the guidelines are useful resources for improving
patient care.
03/14/2019
First Report Managed Care


CURRENT ISSUE

September 2021
Volume 18
Issue 6
Current Issue

Issue Archive




WHAT'S TRENDING?

Transgender Patients: Calculating the Actual Cost
09/11/2017

Dave Muoio

Dave Muoio
An unexpected announcement from President Donald Trump has propelled discussions
on the costs and complications of transgender medical care into the mainstream.
09/11/2017

First Report Managed Care
News
Treatment Reduces Appetite, Weight in Patients With Obesity
10/08/2021
Maria Asimopoulos
Patients with obesity experienced greater reductions in appetite, food
consumption, and body weight while receiving once-weekly subcutaneous
semaglutide 2.4 mg in comparison to placebo.
10/08/2021
First Report Managed Care
News
The Public Backs Medicare Rx Price Negotiation Even After Hearing Both Sides’
Views
10/12/2021

Amanda Michelle Gomez, Kaiser Health News

Amanda Michelle Gomez, Kaiser Health ...
Recent poll results revealed that the majority of Americans support the federal
government negotiating lower drug prices for beneficiaries of both Medicare and
private insurance, despite the pharmaceutical industry's argument that current
prices help fund research.
10/12/2021
First Report Managed Care
Podcasts
Chronic Lymphocytic Leukemia Treatment Demonstrates Long-term Efficacy
09/24/2021
Maria Asimopoulos
Jim Dean, MD, PhD, Imbruvica global development lead and executive medical
director, AbbVie, discusses data from the RESONATE-2 study showing that
single-agent ibrutinib (Imbruvica) improved progression-free and overall
survival for up to seven years in patients with chronic lymphocytic leukemia,
compared to the standard of care.
09/24/2021
First Report Managed Care
Podcasts
Treatment Options and Unmet Need in Non-small Cell Lung Cancer
10/08/2021
Maria Asimopoulos
Alex Spira, MD, PhD, FACP, director of the Virginia Cancer Specialists Research
Institute, medical director at US Oncology Network, provides an overview of
currently available treatment options in non-small cell lung cancer, and
describes the unmet need and challenges in treating this type of cancer.
10/08/2021
First Report Managed Care
VIDEO INSIGHTS

Videos
Psoriasis Treatment Effective at Achieving Skin Clearance
07/26/2021
Maria Asimopoulos
Jeffrey Stark, MD, head of immunology medical affairs, UCB, breaks down the
unique challenges patients with psoriasis face, and discusses the BE RADIANT and
BE SURE studies, both of which indicated that bimekizumab was effective at
achieving skin clearance in this patient population.
07/26/2021
First Report Managed Care
Roundtable
Information Blocking Rules and HIT: Tips for Payer, Provider Compliance
10/05/2021
Maria Asimopoulos
In this roundtable, Scott Collins, president of marketing at ARIA, moderates a
conversation with Matthew A Michela, MBA, president and chief executive officer
of Life Image; Chris Hobson, MD, MBA, chief medical officer of Orion Health; and
Jim Sdoia, MBA, vice president of product management at Lyniate. They discuss
the ways organizations have been struggling with the information bloc...
10/05/2021
Integrated Healthcare Executive
Videos
Treatment for Presymptomatic SMA Proves Effective in Phase 3 Trial
08/16/2021
Julie Gould
Maria Asimopoulos
Shephard Mpofu, MD, senior vice president and chief medical officer, Novartis
Gene Therapies, discusses findings from SPR1NT, a phase 3 clinical trial in
which Zolgensma (onasemnogene abeparvovec-xioi) was effective in treating
patients with presymptomatic spinal muscular atrophy.
08/16/2021
First Report Managed Care
Videos
Psoriasis Treatment Effective at Achieving Skin Clearance
07/26/2021
Maria Asimopoulos
Jeffrey Stark, MD, head of immunology medical affairs, UCB, breaks down the
unique challenges patients with psoriasis face, and discusses the BE RADIANT and
BE SURE studies, both of which indicated that bimekizumab was effective at
achieving skin clearance in this patient population.
07/26/2021
First Report Managed Care
Videos
Genomic Risk Scoring Reduces Unnecessary Chemotherapy for Breast Cancer
06/11/2021
Julie Gould
William Audeh, MD, MS, chief medical officer for Agendia, discusses the results
of the MINDACT study, including how genomic risk scoring in women with breast
cancer could successfully prevent unnecessary chemotherapy treatment, as well as
the importance of understanding tumor biology before choosing a treatment
option.
06/11/2021
First Report Managed Care
Videos
Roundtable: Expert Panel Breaks Down Coverage Options, Various Payer Perceptions
for SMA
06/07/2021
Julie Gould
In this roundtable discussion, moderator Edmund Pezalla, MD, MPH, is joined by
Gary Owens, MD, and Jeffrey Dunn, PharmD, MBA, to examine payer perceptions of
the unmet needs for SMA, review what payers should understand regarding
diagnosis, and provide need-to-know information regarding current treatment and
coverage options.
06/07/2021
First Report Managed Care
Videos
Understanding Therapy Needs, Payer Coverage Challenges for Patients With Asthma
06/01/2021
Edan Stanley
Lakiea Wright, MD, MAT, MPH, Brigham and Women’s Hospital, and medical director,
Thermo Fisher Scientific, describes some of the common challenges of treating
uncontrolled persistent asthma, emphasizes the importance of catering to
individual patients’ needs when choosing therapy options, as well as offers tips
for payers covering this patient population.
06/01/2021
First Report Managed Care
Videos
Utilizing Scheduling Technology to Improve Patient Engagement, Manage Vaccine
Administration
02/05/2021

Danny Sanchez, vice president and general manager, EnlivenHealth, speaks about
the benefits of the CareScheduler tool; outlines how it improves processes for
pharmacists, health plans, and patients; as well as highlights how this kind of
technology can alleviate the many challenges associated with patient engagement
and COVID-19 vaccination administration.
02/05/2021
First Report Managed Care
Videos
Discussing Treatment Paradigm Shifts, Successful Therapy Options for Atopic
Dermatitis
11/13/2020

Vivian Shi, MD, FAAD, associate professor of dermatology, University of Arkansas
for Medical Sciences, describes challenges involved with treating atopic
dermatitis, highlights the benefits of dupilumab—particularly among pediatric
patients, and discusses the how the treatment paradigm for AD is shifting.
11/13/2020
First Report Managed Care
Videos
Improving Care Quality Through Meaningful Partnerships
10/26/2020

Ben Park, MD, president and CEO, American Health Network, part of Optum,
discusses a recent partnership with Suburban Health Organization that will
improve health care quality for Medicare Advantage members and reduce costs, and
shares insight into AHN’s response to the COVID-19 pandemic.
10/26/2020
First Report Managed Care
Videos
Why Health Plans, Systems Should Work Together to Improve Care for Vulnerable
Populations
10/08/2020

Jacob Sattelmair, CEO of Wellframe, a market-leading digital health management
company, discusses the COVID-19 Chronic Condition Population Report and
highlights how the findings help provide both health plans and health care
organizations the capability to extend care in order to improve patient access.
10/08/2020
First Report Managed Care




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