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EEn should restock by 05/05/2024, ideally. EC by 19/05/2024.

AN IMMEDIATE RECALL OF ALL TRANSDERMAL GEL PURCHASED SINCE THE END OF AUGUST IS
IN EFFECT. YOU ARE ADVISED TO DISCONTINUE USE. IF YOU WERE AFFECTED, YOU WILL
HAVE BEEN CONTACTED BY THE EMAIL YOU USED TO PURCHASE FROM US. VIEW OUR INCIDENT
REPORT HERE.

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ESTRADIOL ENANTHATE 10ML (40MG/ML)

Estradiol Enanthate has a longer-acting effect than Estradiol Valerate and
Estradiol Cypionate, allowing for more stable levels and a greater duration
between injections. At 15mg/14 days (0.375ml), a single vial should last a year.

Store in a cool, dry place, out of direct sunlight. Not suitable for
refrigeration (unless for long term storage).

Vials may be prepared for use by removing the circular seal at the top of the
aluminium cap with a fingernail or other thin object to expose the centre of the
stopper. Removing the entire aluminium cap risks contaminating the vial.

If vial stopper becomes compromised, or changes occur in visual clarity or
viscosity of oil solution, discard. If vial coring occurs, discard.

Recommended reading/viewing at the bottom of the page if this is your first time
using injections.

All recommended dosages are suggestions for monotherapy only, pre-orchiectomy,
and should be informed and adjusted based on bloodwork. For bloodwork, Estradiol
levels should be taken at trough, up to 24 hours before your next dose. Target
trough levels should be roughly 200 pg/ml (734 pmol/l) without an antiandrogen,
or 100 pg/ml (367 pmol/l) with an antiandrogen in sufficient dosage to suppress
testosterone production by the testes.

The recommended dosage (15mg/14 days) will likely give you levels easily above
these ranges, except for rare individuals who process the Estradiol ester
abnormally, if you are able to access bloodwork, it is recommended to adapt your
dosage according to target trough levels, either by altering the dosage, or by
altering injection frequency. The current advised dosage will achieve T
suppression in the vast majority of the population, and has been selected for
that purpose on the assumption that many individuals may not have access to
bloodwork. It IS NOT the ideal dosage for YOU. Processing of drugs differs on an
individual basis. In order to achieve levels tailored to your own metabolism of
estradiol while saving money, we recommend obtaining bloodwork when possible.

Estradiol monotherapy is not recommended to cisgender women with intact
endometrial tissue as a form of menopause relief or birth control due to risks
of cancer and endometrial hyperplasia.

For harm reduction purposes it should be noted that the recommended dosages are
only appropriate for adults, and not for children or individuals in their early
teens, for whom dosages should be lower.

Most trans individuals, particularly in cold and light deprived regions are
deficient in Vitamin D. It is recommended to take supplements to account for
this, or spend time outside touching grass during daylight hours.

Vials are theoretically stable for 8+ years, assuming no major alterations in
appearance of oil solution. It is not, however, advisable to keep so many on
hand, in most cases, and we would recommend no more than 3 vials maximum per
individual.

In case of refrigerating at a stable temperature for long term storage, or
storing in a cold place, dissolved estradiol might crash out of solution. This
will appear as small white crystal dust forming on the bottom of the vial which
will lift from the base of the vial when tilted sufficiently to displace it
where it will stick close together in a thin ribbon of crystalline white dust
suspended in oil near the bottom of the vial. To return it to solution, warm the
vial in hot water and shake thoroughly.

Out of stock

 * Additional information
 * Reviews (4)


ADDITIONAL INFORMATION

Ingredients

Estradiol Enanthate (400mg), MCT Oil (53.9%), Benzyl Benzoate (44.1%), Benzyl
Alcohol (2.0%) — All percentages by weight

Concentration

40mg/ml

Total Volume

10ml

Total Active Ingredient

400mg

Final Notes

If vial stopper becomes compromised, or changes occur in visual clarity or
viscosity of oil solution, discard. If vial coring occurs, discard.

Redness or irritation post-injection may be a result of localised irritation,
improper aseptic technique, contamination of the vial, Benzyl Alcohol or Benzyl
Benzoate—a solvent used too facilitate the dissolving of the Estradiol ester
contained within this vial. While not currently available, variations with
lower/absent concentrations of Benzyl Benzoate will be available at a later
date, compounded in a different Carrier Oil.

Benzyl Alcohol is a preservative used in our vials. It is a sensitisation agent,
potentially capable of making you allergic to it. A small percentage of users
might become sensitised to Benzyl Alcohol and experience irritation or swelling
in the region. Please be mindful of this, a newly formed allergy will not
disappear if you ignore it, though in many cases might not be particularly
severe.

This is not solely typical to our injections. Benzyl Alcohol is a common
preservative in many injections, and is highly advised if not outright necessary
for contamination prevention of multi-dose vials. We cannot at present provide
vials without Benzyl Alcohol, since those without are, by necessity, single-use
and become contaminated if not drawn and used in a single sitting. NEVER
subsequently draw from a vial lacking a preservative in two separate sittings.

For added safety from microbial contamination, you might consider using a
sterile, individually sealed 0.22 micron filter needle to draw from our vials
before switching to a different sterile needle. This is not necessary, but it
recommended where possible. Using a single filter needle to both draw and
inject, will result in you conveniently delivering any potentially isolated
microbes or particles directly into your body. Use a filter needle for either
drawing or injecting, never both.

Always follow proper disinfection technique and ensure proper storage and
examination of vials prior to use.

Ensure no large air bubbles remain in your syringe during injection.

If you have congenital heart issues or a family history of breast cancer,
consult a doctor.

Anecdotal observation suggests that severe connective tissue disorders are more
common in trans individuals. If you are hypermobile with a history of joint
pain, subluxation, dislocations, or unexplained weakness of cardiac valves,
please consider the following:
https://www.ehlers-danlos.com/eds-types/
https://www.nhs.uk/conditions/marfan-syndrome/diagnosis/
https://www.hopkinsmedicine.org/health/conditions-and-diseases/loeysdietz-syndrome
https://www.nhs.uk/conditions/joint-hypermobility-syndrome/


4 REVIEWS FOR ESTRADIOL ENANTHATE 10ML (40MG/ML)

 1. Rated 5 out of 5
    
    Louise (verified owner) – May 10, 2023
    
    Super fast next day delivery in a lovely box, looking forward to seeing the
    effects and will update review in 6 months accordingly thank you sooooo
    much!

    
 2. Rated 5 out of 5
    
    Vicky (verified owner) – May 26, 2023
    
    Arrived in good time, and the discreet packaging was certainly discreet (lol
    iykyk), excited to begin my injections and couldn’t recommend more! much
    love to what you do, saving lives x

    
 3. Rated 5 out of 5
    
    Vikkie – June 24, 2023
    
    I’m delighted. Subtle packaging, fast delivery, and after 2 months of use,
    the effects are already clearly apparent. Thank you Vanna

    
 4. Rated 5 out of 5
    
    Lucille Easton (verified owner) – August 20, 2023
    
    After almost a year of use I am now a 38B cup and still going, this is the
    best affordable option for uk transfems when so many delivery methods are so
    much more expensive.

    

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RELATED PRODUCTS


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 * ESTRADIOL CYPIONATE 10ML (40MG/ML)
   
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 * ESTRADIOL UNDECYLATE 10ML (40MG/ML)
   
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IF INJECTING, PLEASE UTILISE THE FOLLOWING RESOURCES PRIOR TO INJECTION! IF IN
DOUBT, ASK A FRIENDLY NURSE AT YOUR LOCAL HOSPITAL. THEY MIGHT BE WILLING TO
SHOW YOU.

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We recommend the vastus lateralis (thigh) injection site for beginners to
self-injection. Please note that subcutaneous and intramuscular injection sites
might not coincide with each other. Find the sites appropriate for your method
of administration. Subcutaneous injection might lead to minor irritation or
redness, intramuscular injection can reduce or resolve that.


FIND INJECTION MATERIALS HERE, OR FROM YOUR LOCAL HOSPITAL / GENERAL PRACTICE.

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Select only sterile, individually wrapped needles and syringes. If using a
sterile, individually wrapped filter unit or filter needle (not a Frontier
Medical Filter Needle which is not applicable for vials), only use the filter
for either drawing or injecting. This will require replacing the needle unit
placed on the tapered top of the syringe after drawing from the vial.

When selecting needle sizes, the size is represented by gauge. Larger needle
diameters(represented by a smaller gauge number – 18G vs 29G) can lead to
greater pain at the injection site if used. However, given the viscosity of oil
injections, be aware that needles with smaller diameters (larger gauge, e.g.
29G) take longer to fill. Individuals with higher body fat may require longer
needles for intramuscular injection. Finally, be aware that insulin syringes
show “insulin units” not millilitres. Each 10 units is equivalent to 0.1ml.
Please keep this in mind when using insulin syringes.


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