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BIO X™
Generation 3 of the go-to 3D bioprinter for cell biologists, tissue engineers
and biomedical researchers.
Get a quote
Book a demo
EXPLORE THE MOST USER-FRIENDLY AND FLEXIBLE BIOPRINTER IN THE WORLD
Brochure
Open biomaterial platform
While we offer an extensive portfolio of biomaterials, we understand the
necessity and importance to make the BIO X compatible with the widest range of
biomaterials available.
Better Cell Safety
Thanks to built-in UV sterilization and a HEPA filter, our patented Clean
Chamber™ technology, the BIO X brings the sterility of the biosafety cabinet to
the benchtop.
Intelligent Printheads for flexibility
Our range of intelligent printheads brings users of the BIO X the utmost
flexibility and interchangeability. The printheads are developed to suit many
different biofabrication projects.
HIGHLIGHTED PUBLICATIONS
Immerse yourself in some of the most recent publications that demonstrate the
power and versatility of the BIO X.
BIOPRINTING A SKIN PATCH WITH DUAL-CROSSLINKED GELATIN (GELMA) AND SILK FIBROIN
(SILMA): AN APPROACH TO ACCELERATING CUTANEOUS WOUND HEALING
Xu, Zhang, Jorgensen et al. (2023) Mater Today Bio 18
The researchers used the bioprinter to print a monolayer round shape with their
custom made G-S Hydrogel as a material, in order to create skin repair patches
for wound healing.
KIRIGAMI-INSPIRED PROGRAMMABLE SOFT MAGNETORESPONSIVE ACTUATORS WITH VERSATILE
MORPHING MODES
Zhu, Wang, Ge et al. (2022) Advanced Science 9 (32), e2203711
Using the BIO X to print magnetoelastic sheets with a custom composite magnetic
ink, using the software to adjust the printing parameters to suit the ink’s
viscosity.
ASTROCYTE 3D CULTURE AND BIOPRINTING USING PEPTIDE FUNCTIONALIZED HYALURONAN
HYDROGELS
Matthiessen, Jury, Rasti Boroojeni et al. (2023) Science and Technology of
Advanced Materials 24(1)
Developing an engineered hyaluronan hydrogel to facilitate the 3D cell culture
of astrocytes with the syringe pump printhead.
DNA STUDIO 4 COMPATIBLE
Generation 3 of the BIO X harnesses the power of the most advanced bioprinting
software available today.
Software
ADVANCED FUNCTIONALITY AND VERSATILITY
Streamline your workflows in a wide range of application areas.
The BIO X’s compatibility with virtually any material makes it the bioprinter of
choice for industry leaders at the forefront of today’s biggest scientific
breakthroughs. Whether you are automating 3D cell cultures, developing complex
tissue constructs or testing new drug compounds, the BIO X 3D bioprinter has the
advanced functionality and versatility to streamline workflows in a wide range
of application areas.
PATENTED CLEAN CHAMBER FOR BETTER CELL SAFETY
Built-in UV sterilization and a HEPA filter bring the sterility of the biosafety
cabinet to the benchtop.
Dual high-powered fans channel air through a HEPA H14 filter to remove 99.995%
of unwanted particles and microorganisms as part of the Clean Chamber™
technology, which also includes UV-C germicidal lights, rounded edges and
positive air pressure.
Initiate Clean Chamber before beginning your experiment to ensure full sterility
around the print area for the duration of the print.
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OPEN MATERIAL PLATFORM, BIOPRINT WITH THE WIDEST RANGE OF MATERIALS
UNIVERSAL BIOMATERIAL COMPATABILITY
We offer an extensive portfolio of bioinks but understand the importance of
material development, which is why we built the BIO X to be an open system that
is compatible with the widest range of materials available. Start developing
your own bioinks with our high-quality bioink development products or explore
our ready-to-print bioinks.
Biomaterials
EXCELLENT TEMPERATURE CONTROL
Bioprint with a wider range of materials and cell types thanks to precise
printhead and printbed temperature control.
With a printhead temperature range of 4°C to 250°C and a printbed temperature
range between 4°C and 65°C, enjoy precise control of temperatures when working
with temperature-sensitive materials like collagen and gelatin. The
possibilities are limitless when you are able to work with a wider range of
materials and cell types.
GROW YOUR RESEARCH WITH MULTIPLE, INTERCHANGEABLE, INTELLIGENT PRINTHEADS
BIO X is the first 3D bioprinter in the world with Intelligent Printheads (iPH),
ensuring your research is always at the forefront.
With an ever-growing list of Intelligent Printheads, the possibilities are
limitless, giving you more freedom to push your research further. Our family of
intelligent printheads is always growing. Each printhead system is made to suit
different biofabrication application, which helps ensure the best possible
result for your 3D bioprint.
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DESIGNED TO DO EVEN MORE
The BIO X’s exceptional features maximize versatility to enhance your success in
the following application areas and beyond.
Application notes
3D cell culture
Three-dimensional cell cultures offer multiple advantages over 2D cell cultures,
including the precise geometrical arrangement of multicellular constructs that
can better recapitulate the native 3D human physiology. Extrusion-based
bioprinters such as the BIO X offers great flexibility when designing 3D cell
culture systems, as they allow researchers to precisely control geometries and
the spatial patterning of cells and other biomaterials.
Organ-on-a-chip
The merger of bioprinting and microfluidics opens the door to on-demand and
personalized organ-on-a-chip models and may replace many preclinical steps in
future drug trials. The BIO X, combined with microfluidic systems like the
VasKit perfusion system allow for complex organ-chip models; and multi-printhead
technology can be used in a one-step fabrication design with spatial
heterogeneity of tissues.
Tissue models and engineering
The BIO X allows for 3D bioprinting with up to three printheads, enabling
multi-material and multi-cell flixbility during small and large tissue
engineering. The world’s your oyster.
Drug delivery
Bioprinters can do more than print with cells, they can also be used for
fabricating hydrogel drug encapsulation and extended-release technologies. The
BIO X bioprinter offers a variety of printheads that are compatible with
different hydrogels. Drugs and bioactives can be mixed within the hydrogels and
printed in patterns such as large patches or micrometer-sized beads.
Soft robotics
Biohybrid soft robotics is an emerging field that combines material science,
biomechanics, sensing, and cells. The advantage of utilizing 3D bioprinting is
the ability to fabricate systems with precise geometries and spatial patterning
of cell types. Such systems can be further integrated or bioprinted with
advanced nanomaterials and biosensors to enable more diverse controls and
functions.
REDUCING THE BARRIERS TO PURCHASE
Select from our various financing options, or reach out to learn more about
refurbished options for a sustainable option to get started with your
bioprinting.
Contact us
TECHNICAL SPECIFICATIONS
Outer Dimensions (L x W x H) 477 mm x 441 mm x 365 mm Weight 18 kg Build Volume
130 mm x 90 mm x 70 mm Build Surface Compatibility Multi-well plates, petri
dishes, glass slides Resolution XY 1 μm Layer Resolution 1 μm Pressure Range
(internal pump) 0-200 kPa Pressure Range (external air supply) 0-700 kPa
Printhead Slots 3 Photocuring Sources (built-in) 365 nm, 405 nm, 485 nm, 520 nm
Printbed Temperature Range 4-65 °C Printhead Temperature Range 4-250
°C (printhead specific) Filter Class, Chamber Air-flow HEPA 14
UV-Sterilization UV-C (275 nm) 20 mW output Calibration Options Manual and
Automatic User Interface Integrated Display, Tablet or Computer OS
Compatibility Windows Connectivity USB Storage, Ethernet Connection Supported
File Formats .gcode, .stl
READY TO CREATE THE FUTURE OF HEALTH?
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