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Text Content

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 * Cancer Testing
 * Physicians
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CANCER IS NOW THE #1 CATASTROPHIC CLAIM FOR SELF-FUNDED HEALTH CARE PLANS

We have a plan to reduce your costs by improving your care
StageZero's programs can help reduce your company's healthcare costs by more
than 50% through early interventions.

LEARN MORE






THE FOLLOWING CASE-STUDY DEMONSTRATES A 58% REDUCTION IN BREAST CANCER COSTS
ALONE THROUGH EARLY INTERVENTION

Presumptions
 * In a target population of 1,000 women 12.9% will develop Breast Cancer in
   their lifetime(1)
 * With a 65% average compliance rate with breast cancer in the U.S. (2) , you
   can expect to find 84 Cancers
 * If only 84 employees have been screened, how do you address the 45 employees
   who have cancer, but have not been diagnosed?

Sample Female
Population
12.9% Lifetime Risk of BC
65% Compliance  Rate Should find This many cancers
Remaining Undiagnosed
(35%)
1000
129
84
45


Predicted Financial Benefit
 * According to a 2022 study by BMC Health Services Research, the average cost
   of treating Stage 1 Breast cancer is $56,507; whereas the cost of treating a
   Stage-4 Breast Cancer is $133,100 (3)
 * The late-stage cost of treating 45 employees with late-stage Breast Cancer is
   $5,989,500
 * If caught early in the same 45 employees, the cost would only be $2,542,815

Treatment Cost 
Stage 1
Treatment Cost 
Stage 4
Cost of Treating 45 Women
at Stage 1
Cost of Treating 45 Women
at Stage 4
Achieved Savings
$56,507
$133,100
$2,542,815
$5,989,500
$3,446,685




A COST AVOIDANCE OF $3,446,685
FOR BREAST CANCER ALONE

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OUR PROCESS IS OUR DIFFERENCE

--------------------------------------------------------------------------------


StageZero provides advanced diagnostics that can not only identify cancer
earlier among employees, but also identify the early warning signs that can lead
to a future cancer diagnosis. This paired with a physician supervised
intervention program run by experienced oncologists can reduce costs for your
organization dramatically.



OUR PROGRAMS ENHANCE YOUR BENEFITS 

--------------------------------------------------------------------------------




ARISTOTLE®
ADRESSING TODAY'S CANCER EARLIER

Did you know 50% of Cancers are still found in the late stages when outcomes are
poor and costs are high(5)?

Aristotle® is a new blood test that can detect the molecular signatures of
multiple cancers from a single sample of blood to help you find cancer earlier
and start treatment when it can dramatically improve patient outcomes. Aristotle
can discretely detect each cancer signature with high sensitivity and
specificity.(4) Today Aristotle can detect 9 specific cancers: 
Ovarian, Breast, Endometrial, Cervical, Bladder, Prostate, Colorectal, Liver
and Stomach. 

Our underlying mRNA technology, The Sentinel Principle, has been validated in
more than 9,000 patients and used by more than 100,000 patients in North
America. (4) 

Learn More




AVRT™
ADDRESSING TOMORROW'S CANCER TODAY

Did you know 40% of the most common cancers are preventable through modifiable
risk factors(6)?

AVRT (pronounced "avert") identifies early risk factors that may lead to cancer
and provides actionable information to help people adopt lifestyle modifications
to help reduce their risk. 

We assess the inflammatory and metabolic pathways that have been demonstrated to
increase the risk of developing cancer and other chronic diseases.

Learn More



LATEST NEWS 


Results from METRICs Study Informs Expansion of StageZero's New Care Oncology
Protocol

StageZero Life Sciences Announces Change of Date of Special Meeting of
Shareholders; Will Combine with AGM in Q2 2023
2/2/23


CONTACT US

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ARISTOTLE - Early Cancer Detection Test AVRT - Cancer Prevention Program The COC
Protocol - Adjunctive Cancer Care All of the above

I am: *
Prospective Patient Physician/Health System/Researcher Employer / Organization
Benefits Advisor Investor



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OUR MISSION

Today the field of cancer research and discovery is focused on the "Moonshot" -
a cure for cancer. But at StageZero Life Sciences we believe in "groundshots"
too by doing whatever we can to help improve outcomes through cancer prevention,
earlier cancer detection and adjunctive cancer therapy to improve cancer
outcomes.


OUR LABORATORY

StageZero Life Sciences U.S. Headquarters is based in Richmond, VA. Our
laboratory in Richmond is registered and certified according to the Clinical
Laboratory Improvement Amendment (CLIA) for high complexity laboratory testing
through the Centers of Medicare and Medicaid Services (CMS). In addition, the
lab is accredited through the U.S. College of American Pathologists (CAP). These
certifications demonstrate our highest commitment to excellence in laboratory
test processing and our passion for patient care. 




References
1. https://www.cancer.gov/types/breast/risk-fact-sheet 
2.https://www.cdc.gov/nchs/hus/topics/mammography.html
3. McGarvey, N., Gitlin, M., Fadli, E. et al. Increased healthcare costs by
later stage cancer diagnosis. BMC Health Serv Res 22, 1155 (2022).
https://doi.org/10.1186/s12913-022-08457-6 American
4. Aristotle: A single blood test for pan-cancer screening. Dempsey AA, Chao S,
Stamatiou D, Pilcz T, Ying J, Burakoff R. Journal of Clinical Oncology 2020;
38:15_suppl e15037
5. Siegel RL, Miller KD, Fuchs HE, Jemal A. Cancer Statistics, 2021. CA Cancer J
Clin. 2021 Jan;71(1):7-33.
6.GBD 2019 Cancer Risk Factors Collaborators. The global burden of cancer
attributable to risk factors, 2010-19: a systematic analysis for the Global
Burden of Disease Study 2019. Lancet. 2022 Aug 20;400(10352):563-591. doi:
10.1016/S0140-6736(22)01438-6. PMID: 35988567. 

Headline on catastrophic cancer claims: 2022 Sun Life Stop-Loss Research Report:
High-cost Claims and Injectable Drug Trends Analysis.

Aristotle™ was developed, and its performance characteristics determined by
Stage Zero Life Sciences, Inc.; they have not been cleared or approved by the US
Food and Drug Administration. 


StageZero Life Sciences. Ltd.
30-70 East Beaver Creek Road
Richmond Hill, Ontario L4B 3B2



StageZero Life Sciences, Inc.
8751 Park Central Drive, Suite 200
Richmond, VA 23227
TEL: 855.420.7140 
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