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Text Content

JOIN A CLINICAL RESEARCH STUDY FOR LUPUS NEPHRITIS

Let’s Tackle Lupus Together

LEARN MORE



Participants must be between 12 and 18 years old




Individuals must be diagnosed with Lupus Nephritis




The goal is to find

potential new treatments




WHAT IS THE POSTERITY STUDY?




Lupus nephritis (LN) is caused by systemic lupus erythematosus (SLE) and occurs
more frequently in younger patients than adults. It’s a serious condition, and
yet limited treatment options exist. Developing a new, effective treatment
option for LN is important. This clinical study will track how safe and
effective a study drug is in combination with the current standard treatment for
LN. The information obtained may help children and adolescents below age 18 with
LN in the future.



Clinical studies are common



Overseen by medical professionals



This study lasts for two years


WHAT TO EXPECT WITH THIS STUDY





4-Week Screening Period

This screening period allows us to carry out some tests to ensure individuals
are eligible to participate in this study.



Double-Blind Treatment Period

Participants are randomly assigned to receive one of the following:

 * Five infusions of the study drug (2 in 3 chance)
 * Five infusions of a placebo (1 in 3 chance)



Treatment Extension Period

At the end of the double-blind treatment, depending on the review, you’ll
either:

 * Continue to receive three additional infusions of what you received before
 * Knowingly receive the study drug for an additional five infusions



Safety Follow-Up Period

We’ll continue to monitor your health and condition once every six months. These
visits will last as long as necessary but at least 12 months after your last
study treatment infusion. You may continue receiving the standard LN treatment
during the safety follow-up period at your study doctor’s discretion.



What Is a Placebo?

A placebo looks just like the study drug and is given the same way. However, it
contains no active medicine and is often called a dummy drug. They're used so
researchers can better evaluate the overall effectiveness of the study drug.



How Is the Study Drug Administered?

The study drug and the placebo will be given as an intravenous (IV) infusion.
This will take between four and five hours to administer each time. A blinded
treatment means that participants won’t know if they’re receiving the study drug
or the placebo.

LEARN MORE


HOW WILL MY HEALTH BE CHECKED?




During the study, you’ll have 11 visits over an approximately 18-month period so
the study team can check your general health and see how you’re responding to
your study treatment. General health check-ins may include:



Physical exams



Blood tests



Urine tests



TEXAS ARTHRITIS CENTER CLINICAL HEALTH STUDIES




Providers at the Texas Arthritis Center participate in clinical research studies
and have served as principal investigators and sub-investigators in several
studies. In these trials, researchers evaluate investigational medications under
carefully controlled conditions. The FDA only approves medications if they are
found to be safe and effective during the clinical research process. It takes a
team of healthcare professionals to conduct a research study. Besides the main
physician who oversees the study, the research team may include other doctors,
nurses, study coordinators, and other healthcare professionals.


THIS STUDY IS OF NO COST TO PARTICIPANTS

Contact us to see if you qualify

LEARN MORE

or call (915) 317-1660

© 2023 TEXAS ARTHRITIS CENTER. ALL RIGHTS RESERVED. 

PRIVACY POLICY

Thank You!