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* * * Redefining Sight for Life. * About Us * Our Global Mission * Core Values * Sustainability * Leadership Team * Board of Directors * Scientific Advisors * Board Committees * Our Technology * Reimagining Ocular Gene Therapy * Therapeutic Protein Biofactories * Sustained Protein Expression * Efficient, Scalable Manufacturing * Pipeline * Our Programs * Ixo-vec * For Patients & Caregivers * Overview * Resources * Our Commitment * Join The Team * Life at Adverum * Our Credo * Our Benefits * Diversity, Equity, and Inclusion * Careers * News & Publications * In the News * Publications * Contact Us * Investors * Overview * News * Events & Presentations * Stock Info * Financials * Governance * Resources Scroll to top Contact Us SEE LIFE. IN VISION. IN ACTION. IN EXPRESSION. REDEFINING SIGHT FOR LIFE. We aspire to develop functional cures through gene therapy to restore vision and prevent blindness. SO YOU SEE. LIFE. OUR GLOBAL MISSION To establish gene therapy as a new standard of care for the leading causes of vision loss. LEARN MORE FOR PATIENTS AND CAREGIVERS Adverum aims to establish gene therapy as a new standard of care for a number of highly prevalent ocular diseases with the aspiration of developing functional cures for these diseases to restore vision and prevent blindness. Our lead program is in wet age-related macular degeneration (wet AMD), which is growing as the leading cause of blindness globally, driven by aging populations combined with treatment options that do not effectively stave off blindness in real-world use. The current standard of care consists of painful eye injections (anti-VEGF therapies) delivered by a retinal specialist recurring every 4-8 weeks. Patients undergoing this burdensome treatment regime often miss treatments, putting them at increased risk of losing their sight. Adverum’s investigational gene therapy Ixo-vec is being developed to offer an in-office, single-administration intravitreal (IVT) therapy with the potential to extend treatment benefit from weeks to years. LEARN MORE OUR TECHNOLOGY Using our proprietary, next-generation adeno-associated virus (AAV) vector platform, we are developing Ixo-vec as a long-lasting treatment for wet AMD. Ixo-vec is a vectorized therapeutic protein (aflibercept) treatment designed to transform retinal cells into ocular biofactories that continually produce and dispense therapeutic doses of aflibercept, a proven effective anti-VEGF treatment. LEARN MORE WE SEE BEYOND Adverum aspires to transform the standard of care, preserve long-term vision, and create a profound societal impact around the globe, by advancing gene therapies for highly prevalent ocular diseases. Leveraging the research capabilities of our IVT platform, we design durable medicines that can be administered in the physician’s office, eliminate the need for frequent retinal injections, in an effort to greatly improve accessibility to treatment. Dr. Laurent Fischer President and Chief Executive Officer NEWS & PUBLICATIONS NEWS & PRESS RELEASES View All ADVERUM BIOTECHNOLOGIES REPORTS THIRD QUARTER 2022 FINANCIAL RESULTS News November 10, 2022 ADVERUM BIOTECHNOLOGIES PRESENTS POSITIVE END OF STUDY RESULTS FROM THE OPTIC TRIAL IN WET AMD INCLUDING TWO-YEAR OUTCOMES FOLLOWING A SINGLE INTRAVITREAL INJECTION OF IXO-VEC (ADVM-022) READ MORE News November 4, 2022 ADVERUM BIOTECHNOLOGIES ANNOUNCES UPCOMING DATA PRESENTATION AT THE RETINA SOCIETY ANNUAL MEETING READ MORE News October 27, 2022 ADVERUM BIOTECHNOLOGIES PRESENTS ANATOMICAL IMPROVEMENTS IN INTRARETINAL AND SUBRETINAL FLUID AFTER A SINGLE IVT INJECTION OF IXO-VEC (ADVM-022) IN THE OPTIC STUDY IN WET AMD READ MORE News September 30, 2022 ADVERUM BIOTECHNOLOGIES TO PARTICIPATE IN THE CHARDAN 6TH ANNUAL GENETIC MEDICINES CONFERENCE READ MORE News September 27, 2022 PUBLICATIONS View All RETINA SOCIETY 2022 Presentations November 4, 2022 AAO 2022 Presentations September 30, 2022 ASRS 2022 Presentations July 13, 2022 MACULA SOCIETY ANNUAL MEETING Presentations June 8, 2022 ASGCT 2022 Presentations May 19, 2022 CONTACT US Interested in learning more and getting an inside view of Adverum? We are eager to hear from you. Please complete our contact form to engage with one of our team members. CONTACT US We are driven to establish gene therapy as a new standard of care for the leading causes of vision loss. * * * ABOUT US * About Us * Our Global Mission * Core Values * Sustainability * Leadership Team * Board of Directors * Scientific Advisors * Board Committees OUR TECHNOLOGY * Our Technology * Reimagining Ocular Gene Therapy * Therapeutic Protein Biofactories * Sustained Protein Expression * Efficient, Scalable Manufacturing PIPELINE * Pipeline * Our Programs * Ixo-vec FOR PATIENTS & CAREGIVERS * For Patients & Caregivers * Overview * Resources * Our Commitment INVESTORS * Investors * Overview * News * Events & Presentations * Stock Info * Financials * Governance * Resources JOIN THE TEAM * Join The Team * Life at Adverum * Our Credo * Our Benefits * Diversity, Equity, and Inclusion * Careers NEWS & PUBLICATIONS * News & Publications * In the News * Publications SEEING BEYOND BLOG CONTACT US * Contact Us Privacy PolicyCommunity Guidelines ADVERUM Adverum Biotechnologies, Inc., 100 Cardinal Way, Redwood City, CA 94063 Tel: 650-656-9323Fax: 650.649.1995 ©Adverum Biotechnologies, Inc. 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