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ISAAC CARRICO

Chemistry

Lab Website

Chemical biology, bioorganic chemistry, and protein engineering; Introduction of
unnatural monomers into biopolymers for tracking or perturbing biological
processes; Metabolic engineering to introduce unnatural functionality into
biosynthetic processes, focusing on remodeling eukaryotic virus surfaces for
gene therapy and vaccine applications; Protein engineering to enhance protein
pharmaceuticals by reducing protease interactions and immunogenicity through
introduction of unnatural functionality; Development of fast, chemoselective
bioorthogonal reactions for specific chemical modifications under physiological
conditions, with emphasis on electrocyclic reactions aided by molecular
recognition events.


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