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 * Important Safety Information
 * Prescribing Information
 * For Eye Care Professionals
 * Sign up

 * What is GA?
 * How IZERVAY works
 * Getting started
 * Get support


SLOW GA


WITH IZERVAY



IZERVAY is FDA-approved to treat geographic atrophy (GA). IZERVAY slows GA by
directly targeting C5, a key source of retinal cell death and loss of
photoreceptors.

Why treat GA early?




“SLOWING GA MEANS HOPE—HOPE THAT I'LL PRESERVE MY VISION LONGER, WHICH CAN HELP
ME KEEP DOING THE THINGS I LOVE.” – MARY, GA PATIENT


SHIFT GA TO THE SLOW LANE


View transcript

If you’re living with dry AMD, you may be at risk for developing geographic
atrophy, or GA.



GA can be unpredictable—and progress rapidly—leading to irreversible vision
loss.



Now there's something you can do to...



Slow. It. Down.



Get it goin’ slower.



Ask your doctor about IZERVAY.



I. ZER. VAY.



Gets GA goin’ slower.



IZERVAY is an eye injection.



Don’t take it if you have an infection or active swelling in or around your eye.



IZERVAY can cause eye infection, retinal detachment, or increased risk of wet
AMD.



IZERVAY may temporarily increase eye pressure.



Do not drive or use machinery until vision has recovered after an eye injection
or exam.



IZERVAY is proven to slow GA progression which may help preserve vision longer.



I. ZER. VAY.



Gets GA goin’ slower.



So shift gears and get going.



Don’t delay. Ask your doctor about IZERVAY.




SHIFT GA TO THE SLOW LANE

Watch the IZERVAY TV Spot here.

To watch more videos about GA and IZERVAY, visit the video library.

Explore more videos

Learn more about your condition

What is GA?

Learn how IZERVAY can help

How IZERVAY works

Find out what to expect from treatment

Getting started


GET SUPPORT FOR THE NEXT LEG OF YOUR GA JOURNEY

Find out more about financial assistance, community support, and advocacy groups
for people with GA.

Get support

INDICATION AND IMPORTANT SAFETY INFORMATION

WHAT IS IZERVAYTM?

IZERVAY (avacincaptad pegol intravitreal solution) is a prescription eye
injection, used to treat geographic atrophy (GA), the advanced form of dry
age-related macular degeneration (AMD).

WHAT IS THE MOST IMPORTANT INFORMATION I SHOULD KNOW ABOUT IZERVAY?

Do NOT receive IZERVAY if you:

 * Have an infection in or around your eye
 * Have active swelling in or around your eye that may include pain and redness

IZERVAY CAN CAUSE SERIOUS SIDE EFFECTS:

 * Eye injections like the one for IZERVAY can cause an eye infection
   (endophthalmitis) or separation of layers of the retina (retinal detachment).
 * Call your healthcare provider right away if you have redness of the eye, eye
   pain, increased discomfort, worsening eye redness, blurred or decreased
   vision, an increased number of small specks floating in your vision, flashes
   of light, or increased sensitivity to light.
 * There is a risk of developing wet AMD with IZERVAY. You should report any
   symptoms (visual distortions such as straight lines seeming bent,
   deterioration in vision, dark spots, loss of central vision) to your
   healthcare provider to monitor.
 * IZERVAY may cause a temporary increase in eye pressure after the injection.
   Your healthcare provider will monitor this after each injection.

BEFORE RECEIVING IZERVAY TELL YOUR HEALTHCARE PROVIDER ABOUT ALL OF YOUR MEDICAL
CONDITIONS INCLUDING IF YOU:

 * Have a history of seeing flashes of light or small specks floating in your
   vision and if you have a sudden increase of size and number of these specks.
 * Have high pressure in the eye or if you have glaucoma.
 * Are pregnant or breastfeeding, think you may be pregnant, or are planning to
   have a baby, ask your doctor for advice before taking this medicine.
 * Are taking any medications, including prescription and over-the-counter
   medicines, vitamins, and herbal supplements. Tell your healthcare provider
   about any medicine you take.

WHAT SHOULD I AVOID WHILE RECEIVING IZERVAY?

 * Your vision may be impaired after receiving an eye injection or after an eye
   exam. Do not drive or use machinery until your vision has recovered
   sufficiently.

WHAT ARE THE MOST COMMON SIDE EFFECTS OF IZERVAY?

 * Blood in the white of the eye
 * Increase in eye pressure
 * Blurred vision
 * Wet age-related macular degeneration

These are not all the possible side effects of IZERVAY. Tell your healthcare
provider about any side effect that bothers you or that does not go away.

Call your healthcare provider for medical advice about side effects. You are
encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Please see full Prescribing Information for more information.

INDICATION AND IMPORTANT SAFETY INFORMATION

WHAT IS IZERVAYTM?

IZERVAY (avacincaptad pegol intravitreal solution) is a prescription eye
injection, used to treat geographic atrophy (GA), the advanced form of dry
age-related macular degeneration (AMD).

WHAT IS THE MOST IMPORTANT INFORMATION I SHOULD KNOW ABOUT IZERVAY?

Do NOT receive IZERVAY if you:

 * Have an infection in or around your eye
 * Have active swelling in or around your eye that may include pain and redness

IZERVAY CAN CAUSE SERIOUS SIDE EFFECTS:

 * Eye injections like the one for IZERVAY can cause an eye infection
   (endophthalmitis) or separation of layers of the retina (retinal detachment).
 * Call your healthcare provider right away if you have redness of the eye, eye
   pain, increased discomfort, worsening eye redness, blurred or decreased
   vision, an increased number of small specks floating in your vision, flashes
   of light, or increased sensitivity to light.
 * There is a risk of developing wet AMD with IZERVAY. You should report any
   symptoms (visual distortions such as straight lines seeming bent,
   deterioration in vision, dark spots, loss of central vision) to your
   healthcare provider to monitor.
 * IZERVAY may cause a temporary increase in eye pressure after the injection.
   Your healthcare provider will monitor this after each injection.

BEFORE RECEIVING IZERVAY TELL YOUR HEALTHCARE PROVIDER ABOUT ALL OF YOUR MEDICAL
CONDITIONS INCLUDING IF YOU:

 * Have a history of seeing flashes of light or small specks floating in your
   vision and if you have a sudden increase of size and number of these specks.
 * Have high pressure in the eye or if you have glaucoma.
 * Are pregnant or breastfeeding, think you may be pregnant, or are planning to
   have a baby, ask your doctor for advice before taking this medicine.
 * Are taking any medications, including prescription and over-the-counter
   medicines, vitamins, and herbal supplements. Tell your healthcare provider
   about any medicine you take.

WHAT SHOULD I AVOID WHILE RECEIVING IZERVAY?

 * Your vision may be impaired after receiving an eye injection or after an eye
   exam. Do not drive or use machinery until your vision has recovered
   sufficiently.

WHAT ARE THE MOST COMMON SIDE EFFECTS OF IZERVAY?

 * Blood in the white of the eye
 * Increase in eye pressure
 * Blurred vision
 * Wet age-related macular degeneration

These are not all the possible side effects of IZERVAY. Tell your healthcare
provider about any side effect that bothers you or that does not go away.

Call your healthcare provider for medical advice about side effects. You are
encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Please see full Prescribing Information for more information.

 * What is GA?
 * How IZERVAY works
 * Getting started
 * Get support
 * Sign up

 * For Eye Care Professionals
 * Prescribing Information
 * Terms of Use
 * Privacy Policy
 * IZERVAY Website Accessibility Statement

This website is intended for US residents only.

Copyright © 2024 Astellas Pharma Inc. or its affiliates.
All trademarks are the property of their respective owners. US-AP-2400211
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