onlinelibrary.wiley.com
Open in
urlscan Pro
2606:4700:7::a29f:8257
Public Scan
Submitted URL: https://doi.org/10.1111/j.1365-2265.2011.04299.x
Effective URL: https://onlinelibrary.wiley.com/doi/10.1111/j.1365-2265.2011.04299.x
Submission: On February 17 via manual from AU — Scanned from DE
Effective URL: https://onlinelibrary.wiley.com/doi/10.1111/j.1365-2265.2011.04299.x
Submission: On February 17 via manual from AU — Scanned from DE
Form analysis 8 forms found in the DOM
Name: thisJournalQuickSearch — GET /action/doSearch
<form action="/action/doSearch" name="thisJournalQuickSearch" method="get" title="Quick Search">
<div class="input-group option-0"><label for="searchField0" class="hiddenLabel">Search term</label><input type="search" name="AllField" id="searchField0" placeholder="Search" onfocus="this.value = this.value;" data-auto-complete-max-words="7"
data-auto-complete-max-chars="32" data-contributors-conf="3" data-topics-conf="3" data-publication-titles-conf="3" data-history-items-conf="3" value="" tabindex="9" class="autocomplete actualQSInput quickSearchFilter ui-autocomplete-input"
autocomplete="off"><span role="status" aria-live="polite" class="ui-helper-hidden-accessible"></span><input type="hidden" name="SeriesKey" value="13652265">
<div class="search-options-wrapper quickSearchFilter">
<a href="https://onlinelibrary.wiley.com/search/advanced?publication=13652265" title="" tabindex="12" class="advanced"> Advanced Search</a><a href="https://onlinelibrary.wiley.com/search/advanced?publication=13652265#citation" title="" tabindex="12" class="citation"> Citation Search</a>
</div>
</div><button type="submit" title="Search" tabindex="11" aria-label="Submit Search" class="btn quick-search__button icon-search"></button>
</form>Name: defaultQuickSearch — GET https://onlinelibrary.wiley.com/action/doSearch
<form action="https://onlinelibrary.wiley.com/action/doSearch" name="defaultQuickSearch" method="get" title="Quick Search">
<div class="input-group option-1"><label for="searchField1" class="hiddenLabel">Search term</label><input type="search" name="AllField" id="searchField1" placeholder="Search" onfocus="this.value = this.value;" data-auto-complete-max-words="7"
data-auto-complete-max-chars="32" data-contributors-conf="3" data-topics-conf="3" data-publication-titles-conf="3" data-history-items-conf="3" value="" tabindex="9" class="autocomplete actualQSInput quickSearchFilter ui-autocomplete-input"
autocomplete="off"><span role="status" aria-live="polite" class="ui-helper-hidden-accessible"></span>
<div class="search-options-wrapper quickSearchFilter">
<a href="https://onlinelibrary.wiley.com/search/advanced" title="" tabindex="12" class="advanced"> Advanced Search</a><a href="https://onlinelibrary.wiley.com/search/advanced#citation" title="" tabindex="12" class="citation"> Citation Search</a>
</div>
</div><button type="submit" title="Search" tabindex="11" aria-label="Submit Search" class="btn quick-search__button icon-search"></button>
</form>POST
<form method="post">
<fieldset>
<legend>Please review our <a href="https://onlinelibrary.wiley.com/termsAndConditions" target="_blank">Terms and Conditions of Use</a> and check box below to share full-text version of article.</legend>
<div class="input-group"><label for="terms-and-conditions" class="checkbox--primary"><input id="terms-and-conditions" type="checkbox" value="yes" required="" name="terms-and-conditions"
data-ajax-link="/action/generateShareUrl?doi=10.1111/j.1365-2265.2011.04299.x&shareType=P2P&format=FULL-TEXT" data-shareable-link=""><span class="label-txt">I have read and accept the Wiley Online Library Terms and Conditions of
Use</span></label></div>
</fieldset>
<hr class="separator">
<div class="shareable"><label>Shareable Link</label>
<p>Use the link below to share a full-text version of this article with your friends and colleagues. <a href="https://onlinelibrary.wiley.com/researchers/tools-resources/sharing" target="_blank" class="emphasis">Learn more.</a></p>
<div class="shareable__box">
<div class="shareable__text">
<div class="shareable__field"><span id="shareable__text"></span><textarea tabindex="-1" class="shareable__text-area"></textarea></div>
</div><button type="submit" disabled="" class="btn shareable__btn">Copy URL</button>
</div>
<div class="error shareable__error hidden"></div>
</div>
</form>POST /action/doLogin?societyURLCode=
<form action="/action/doLogin?societyURLCode=" class="bordered" method="post"><input type="hidden" name="id" value="67065c09-4a88-49cd-934c-ac707951d35c">
<input type="hidden" name="popup" value="true">
<input type="hidden" name="loginUri" value="/doi/10.1111/j.1365-2265.2011.04299.x">
<input type="hidden" name="redirectUri" value="/doi/10.1111/j.1365-2265.2011.04299.x">
<input type="hidden" name="loginUri" value="/doi/10.1111/j.1365-2265.2011.04299.x">
<div class="input-group">
<div class="label">
<label for="username">Email or Customer ID</label>
</div>
<input id="username" class="login" type="text" name="login" value="" size="15" placeholder="Enter your email" autocorrect="off" spellcheck="false" autocapitalize="off" required="true">
<div class="actions">
</div>
</div>
<div class="input-group">
<div class="label">
<label for="password">Password</label>
</div>
<input id="password" class="password" type="password" name="password" value="" autocomplete="off" placeholder="Enter your password" autocorrect="off" spellcheck="false" autocapitalize="off" required="true">
<span class="password-eye-icon icon-eye hidden"></span>
</div>
<div class="actions">
<a href="/action/requestResetPassword" class="link show-request-reset-password">
Forgot password?
</a>
</div>
<div class="loginExtraBeans-dropZone" data-pb-dropzone="loginExtraBeans">
</div>
<div class="align-end">
<span class="submit " disabled="disabled">
<input class="button btn submit primary no-margin-bottom accessSubmit" type="submit" name="submitButton" value="Log In" disabled="disabled">
</span>
</div>
</form>POST /action/changePassword
<form action="/action/changePassword" method="post">
<div class="message error"></div>
<input type="hidden" name="submit" value="submit">
<div class="input-group">
<div class="label">
<label for="a589574e-bb98-4c6e-8fed-67365ff05357-old">Old Password</label>
</div>
<input id="a589574e-bb98-4c6e-8fed-67365ff05357-old" class="old" type="password" name="old" value="" autocomplete="off">
<span class="password-eye-icon icon-eye hidden"></span>
</div>
<div class="input-group">
<div class="label">
<label for="a589574e-bb98-4c6e-8fed-67365ff05357-new">New Password</label>
</div>
<input id="a589574e-bb98-4c6e-8fed-67365ff05357-new" class="pass-hint new" type="password" name="new" value="" autocomplete="off">
<span class="password-eye-icon icon-eye hidden"></span>
<div class="password-strength-indicator" data-min="10" data-max="32" data-strength="3">
<span class="text too-short">Too Short</span>
<span class="text weak">Weak</span>
<span class="text medium">Medium</span>
<span class="text strong">Strong</span>
<span class="text very-strong">Very Strong</span>
<span class="text too-long">Too Long</span>
</div>
</div>
<input class="button primary submit" type="submit" value="Submit" disabled="disabled">
</form>POST /action/registration
<form action="/action/registration" class="registration-form" method="post"><input type="hidden" name="redirectUri" value="/doi/10.1111/j.1365-2265.2011.04299.x">
<div class="input-group">
<div class="label">
<label for="4e647394-f751-4441-baa4-df426bca4b6e.email">Email or Customer ID</label>
</div>
<input id="4e647394-f751-4441-baa4-df426bca4b6e.email" class="email" type="text" name="email" value="" size="15">
</div>
<div class="submit">
<input class="button submit primary" type="submit" value="Register" disabled="disabled">
</div>
</form>POST /action/requestResetPassword
<form action="/action/requestResetPassword" class="request-reset-password-form" method="post"><input type="hidden" name="requestResetPassword" value="true">
<div class="input-group">
<div class="input-group">
<div class="label">
<label for="email">Email or Customer ID</label>
</div>
<input id="email" class="email" type="text" name="email" value="" size="15" placeholder="Enter your email" autocorrect="off" spellcheck="false" autocapitalize="off">
</div>
</div>
<div class="password-recaptcha-ajax"></div>
<div class="message error"></div>
<div class="form-btn">
<input class="button btn primary submit" type="submit" name="submit" value="RESET PASSWORD" disabled="disabled">
</div>
</form>POST /action/requestUsername
<form action="/action/requestUsername" method="post"><input type="hidden" name="requestUsername" value="requestUsername">
<div class="input-group">
<div class="label">
<label for="ac834f24-aa07-4ad2-9d13-f77c843f21cb.email">Email or Customer ID</label>
</div>
<input id="ac834f24-aa07-4ad2-9d13-f77c843f21cb.email" class="email" type="text" name="email" value="" size="15">
</div>
<div class="username-recaptcha-ajax">
</div>
<input class="button primary submit" type="submit" name="submit" value="Submit" disabled="disabled">
<div class="center">
<a href="#" class="cancel">Close</a>
</div>
</form>Text Content
* Skip to Article Content * Skip to Article Information Working off-campus? Learn about our remote access options Search withinThis JournalAnywhere * Search term Advanced Search Citation Search * Search term Advanced Search Citation Search Login / Register Clinical Endocrinology Volume 77, Issue 4 p. 537-540 Original Article FGF23 CONTRIBUTES TO INSULIN SENSITIVITY IN OBESE ADOLESCENTS – PRELIMINARY RESULTS Malgorzata Wojcik, Malgorzata Wojcik Pediatric and Adolescent Endocrinology Department, Chair of Pediatrics, Jagiellonian University, Collegium Medicum Children’s University Hospital Search for more papers by this author Katarzyna Dolezal-Oltarzewska, Katarzyna Dolezal-Oltarzewska Children’s University Hospital Search for more papers by this author Dominika Janus, Dominika Janus Pediatric and Adolescent Endocrinology Department, Chair of Pediatrics, Jagiellonian University, Collegium Medicum Children’s University Hospital Search for more papers by this author Dorota Drozdz, Dorota Drozdz Children’s University Hospital Pediatric Nephrology Department, Chair of Pediatrics, Jagiellonian University, Collegium Medicum Search for more papers by this author Krystyna Sztefko, Krystyna Sztefko Children’s University Hospital Department of Clinical Biochemistry, Pediatric Institute, Jagiellonian University, Collegium Medicum, Krakow, Poland Search for more papers by this author Jerzy B. Starzyk, Jerzy B. Starzyk Pediatric and Adolescent Endocrinology Department, Chair of Pediatrics, Jagiellonian University, Collegium Medicum Children’s University Hospital Search for more papers by this author Malgorzata Wojcik, Malgorzata Wojcik Pediatric and Adolescent Endocrinology Department, Chair of Pediatrics, Jagiellonian University, Collegium Medicum Children’s University Hospital Search for more papers by this author Katarzyna Dolezal-Oltarzewska, Katarzyna Dolezal-Oltarzewska Children’s University Hospital Search for more papers by this author Dominika Janus, Dominika Janus Pediatric and Adolescent Endocrinology Department, Chair of Pediatrics, Jagiellonian University, Collegium Medicum Children’s University Hospital Search for more papers by this author Dorota Drozdz, Dorota Drozdz Children’s University Hospital Pediatric Nephrology Department, Chair of Pediatrics, Jagiellonian University, Collegium Medicum Search for more papers by this author Krystyna Sztefko, Krystyna Sztefko Children’s University Hospital Department of Clinical Biochemistry, Pediatric Institute, Jagiellonian University, Collegium Medicum, Krakow, Poland Search for more papers by this author Jerzy B. Starzyk, Jerzy B. Starzyk Pediatric and Adolescent Endocrinology Department, Chair of Pediatrics, Jagiellonian University, Collegium Medicum Children’s University Hospital Search for more papers by this author First published: 22 November 2011 https://doi.org/10.1111/j.1365-2265.2011.04299.x Citations: 32 Małgorzata Wojcik, Pediatric and Adolescent Endocrinology Department, Chair of Pediatrics, Jagiellonian University, Collegium Medicum, Ul. Wielicka 265, 30-663 Krakow, Poland. Tel.: 0048126581277; Fax: 00486581005; E-mail: malgorzata.wojcik@uj.edu.pl Read the full text About * * RELATED * INFORMATION * PDF PDF Tools * Request permission * Export citation * Add to favorites * Track citation ShareShare Give access Share full text access Close modal Share full-text access Please review our Terms and Conditions of Use and check box below to share full-text version of article. I have read and accept the Wiley Online Library Terms and Conditions of Use -------------------------------------------------------------------------------- Shareable Link Use the link below to share a full-text version of this article with your friends and colleagues. Learn more. Copy URL Share a link Share on * Facebook * Twitter * Linked In * Reddit * Wechat ABSTRACT Fibroblast growth factor-23 (FGF23) is a hormonal regulator of circulating phosphate and vitamin D levels. Recent investigations revealed that besides a key role in the pathogenesis of calcium–phosphorus disorders, in some patients FGF23 may be an indicator of cardiovascular complications. As a ‘hormone-like’ factor, it may also be involved in some metabolic processes, especially in the metabolism of glucose and fat. Its potential contribution to metabolic syndrome (MS) development has not been confirmed yet. Objective The study was to examine the possible correlations between FGF23 serum levels and body composition, blood pressure and selected parameters of glucose, insulin and fat metabolism in adolescents with simple obesity. Patients and design In 68 (35 female) adolescents (mean age 13·9 years) with simple obesity [mean BMI SDS 4·9 (95% CI 4·4–5·4)], the levels of FGF23, total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol and triglycerides were measured. Standard oral glucose tolerance tests were performed with the assessment of fasting and after 120′ postload glucose and insulin levels; the insulin resistance index HOMA-IR was calculated. Results Regardless of gender, there was a significant inverse correlation between FGF23 and fasting insulin level (r = −0·3), as well as HOMA-IR (r = −0·29). Multiple regression model showed the independent association between FGF23 and HOMA-IR. Conclusion FGF23 seems to be a novel factor contributing to insulin sensitivity. Further investigations are needed to define its role in the development of MS. CITING LITERATURE Volume77, Issue4 October 2012 Pages 537-540 * RELATED * INFORMATION RECOMMENDED * Validation of the oral glucose insulin sensitivity index to assess insulin sensitivity in Japanese subjects for use in clinical practice M. Kanauchi, European Journal of Clinical Investigation * Comparison among different insulin sensitivity indices in obese patients E. Mannucci, G. Bardini, F. Rotella, C. M. Rotella, Diabetic Medicine * Insulin secretory capacity and insulin sensitivity in impaired fasting glucose in Japanese Rie Mitsui, Mitsuo Fukushima, Ataru Taniguchi, Yoshikatsu Nakai, Sae Aoyama, Yoshitaka Takahashi, Hideaki Tsuji, Daisuke Yabe, Koichiro Yasuda, Takeshi Kurose, Toshiko Kawakita, Yutaka Seino, Nobuya Inagaki, Journal of Diabetes Investigation * Regulation of fibroblast growth factor 23 (FGF23) in health and disease Ludmilla Bär, Christos Stournaras, Florian Lang, Michael Föller, FEBS Letters * Insulin sensitivity across the lifespan from obese adolescents to obese adults with impaired glucose tolerance: Who is worse off? Silva Arslanian, Joon Young Kim, Alexis Nasr, Fida Bacha, Hala Tfayli, SoJung Lee, Frederico G. S. Toledo, Pediatric Diabetes Close Figure Viewer Return to Figure Previous FigureNext Figure Caption Download PDF back ADDITIONAL LINKS ABOUT WILEY ONLINE LIBRARY * Privacy Policy * Terms of Use * Cookies * Accessibility * Publishing Policies HELP & SUPPORT * Contact Us * Training and Support * DMCA & Reporting Piracy OPPORTUNITIES * Subscription Agents * Advertisers & Corporate Partners CONNECT WITH WILEY * The Wiley Network * Wiley Press Room Copyright © 1999-2022 John Wiley & Sons, Inc. All rights reserved The full text of this article hosted at iucr.org is unavailable due to technical difficulties. LOG IN TO WILEY ONLINE LIBRARY Email or Customer ID Password Forgot password? NEW USER > INSTITUTIONAL LOGIN > CHANGE PASSWORD Old Password New Password Too Short Weak Medium Strong Very Strong Too Long PASSWORD CHANGED SUCCESSFULLY Your password has been changed CREATE A NEW ACCOUNT Email or Customer ID Returning user FORGOT YOUR PASSWORD? Enter your email address below. Email or Customer ID Please check your email for instructions on resetting your password. If you do not receive an email within 10 minutes, your email address may not be registered, and you may need to create a new Wiley Online Library account. REQUEST USERNAME Can't sign in? Forgot your username? Enter your email address below and we will send you your username Email or Customer ID Close If the address matches an existing account you will receive an email with instructions to retrieve your username Close crossmark popup