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RESEARCHER PORTRAIT:
THE INNOVATOR, MAIKE SANDER




VIDEO


UNDERSTANDING THE MOLECULAR BASIS OF HEALTH AND DISEASE


INNOVATING MEDICAL THERAPIES AND CLINICAL DIAGNOSTICS

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OUR RESEARCH

Research at the Max Delbrück Center aims to elucidate the molecular mechanisms
of health and disease, and translate those findings into medical practice.

 * 82 research labs
 * 18 technology platforms
 * 25 ERC Grant laureates


OUR NEWSLETTER

Stay connected and find out more about our research, innovations and campus
life! Subscribe now to our monthly newsletter Insights.

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Further information


RESEARCH HIGHLIGHTS

Our research teams publish around 450 specialist articles every year. Our
research highlights can be found here, presented in a comprehensible format.

More information

Selection of research highlights




RESEARCH NEWS & EVENTS

Science October 30, 2024


THE INNOVATOR

As Scientific Director of Max Delbrück Center, Maike Sander is driving a bold
shift toward interdisciplinary research to address the health challenges of our
time. As a diabetes researcher, her next frontier is to use organ-on-a-chip
technologies to build more accurate models of the human pancreas.
Science October 30, 2024


BEYOND CHATGPT: FOUNDATION MODELS FOR RESEARCH

Foundation models are complex AI applications with enormous potential. Trained
on vast datasets from medicine, climate, or material science, they can uncover
new relationships and make predictions. Helmholtz is supporting this pioneering
work, with €5.55 million going to the Max Delbrück Center.
Science October 29, 2024


FROM RESEARCH TO APPLICATION

The Max Delbrück Center proudly welcomes Dr. Nevine Shalaby as the new Head of
the Innovation and Entrepreneurship Department. With a rich background in
genetics and industry, she aims to drive research impact, foster spin-offs, and
strengthen industry partnerships, aligned with the Strategy 2030.
October 25, 2024


CANCER RISK LINKED TO P53 IN ULCERATIVE COLITIS

Researchers in the lab of Michael Sigal at the Max Delbrück Center and Charité –
Universitätsmedizin Berlin have elucidated the role of the p53 gene in
ulcerative colitis. The study, published in “Science Advances,” suggests a
potential new drug target to stop disease progression to cancer.
October 23, 2024


A DIALOGUE BETWEEN SCIENCE AND ART

From November 1 to 10, 2024, researchers and science enthusiasts will come
together during Berlin Science Week to discuss important questions about science
and society. Kicking off the week, the Max Delbrück Center will present its
photo exhibition “Discoverers” for the first time.
Science October 21, 2024


NAVIGATING CANCER TREATMENT WITH THE HELP OF AI

Cancer treatment has become complex. An AI based online tool developed by
researchers at the Max Delbrück Center can already help oncologists and cancer
patients find the most up to date personalized treatment.
October 08, 2024


PERSPECTIVES FOR THE MEDICINE OF THE FUTURE

What opportunities lie ahead for the future of medical research and healthcare?
Scientists from the Helmholtz Association share their ideas with decision-makers
from science, politics, patient organizations, biotech, and the pharmaceutical
industry at the first Helmholtz Health Summit in Berlin.
Science September 30, 2024


MEDICINE NEEDS MORE INNOVATION

We at the Helmholtz Association have everything we need to leverage the
potential of biomedical engineering in Germany. We simply need to assemble all
the puzzle pieces thoughtfully and unite people who have never collaborated
before, says our Scientific Director Maike Sander.
Science September 30, 2024


THE PIONEER OF SINGLE-CELL SEQUENCING

Ashley Sanders, Group Leader of the Genome Instability and Somatic Mosaicism
Lab, developed a technique to sequence strands of DNA in single cells. Today it
is the most accurate method to detect DNA rearrangements. She hopes the
technique will help reveal clues on how diseases develop.
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PUBLICATIONS

2025


CONCURRENT PROFILING OF LOCALIZED TRANSCRIPTOME AND RNA DYNAMICS IN NEURONS BY
SPATIAL SLAMSEQ

Methods Mol Biol
December, 2024


CHARACTERIZATION OF TWO IPSC LINES FROM PATIENTS WITH MATERNALLY INHERITED LEIGH
(MILS) AND NEUROPATHY, ATAXIA, AND RETINITIS PIGMENTOSA (NARP) SYNDROME CARRYING
THE MT-ATP6 M.8993 T>G MUTATION AT DIFFERENT DEGREES OF HETEROPLASMY

Stem Cell Res
December, 2024


A POINT-OF-RESEARCH DECISION IN SYNOVIAL TISSUE ENGINEERING: MESENCHYMAL STROMAL
CELLS, TISSUE DERIVED FIBROBLAST OR CTGF-MEDIATED MESENCHYMAL-TO-FIBROBLAST
TRANSITION

Eur J Cell Biol
December, 2024


IN VITRO TESTING OF DRUG RESPONSE IN PRIMARY MULTIPLE MYELOMA CELLS USING A
MICROWELL-BASED TECHNOLOGY

Leuk Res

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CAREER & TRAINING

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PHD AT THE MAX DELBRÜCK CENTER

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Discovery for tomorrow's medicine

Max Delbrück Center for Molecular Medicine in the Helmholtz Association
(Max Delbrück Center)

Robert-Rössle-Str. 10
13125 Berlin (street address)
13092 Berlin (postal address)
Germany

Phone: +49 30 9406-0

Travel directions

Berlin Institute for Medical Systems Biology of the Max Delbrück Center
(MDC-BIMSB)

Hannoversche Straße 28
10115 Berlin
Germany

Phone: +49 30 9406-1300

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Helmholtz-Institut für translationale AngioCardioScience (HI-TAC) des Max
Delbrück Center

Standort Medizinische Fakultät Mannheim & Medizinische Fakultät Heidelberg der
Universität Heidelberg


Phone: +49 30 9406-0


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