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SimpleMicrofluidics
 * DIY Microfluidics Prototyping
   * Duplicate an Existing Circuit
   * PDMS Fabrication Techniques
     * Overview
     * What is PDMS?
     * 3D Printed Mold
     * Metal Micromilling
     * Puffy Paint Mold
     * Duplicate an Existing Circuit
     * ABS Sheet Mold
     * ESCARGOT
   * PDMS Surface Modification
     * Corona Discharge
     * SolGel (TEOS)
     * SolGel (Glass)
     * SolGel (Borosilicate Glass)
     * O2 Plasma (Plasma Cleaner)
     * O2 Plasma (Microwave)
     * Surfactant In-molding
     * PEGMEM Modification
     * PVA Deposition
     * PVP Coating
     * Silinization
     * Chemical Micropatterning
     * Polymer Brushing (Grafting-to)
     * Polymer Brushing (Grafting-from)
     * Silicon-Oxide Layer
   * Paper Fabrication Techniques
     * Overview
     * Laser Cutting
     * Wax Printing
     * Wax Stamping
     * Wax Tracing
     * Paper and Tape
     * Stamp Printing Ink
     * Stamp Printing PDMS
     * Flash Foam Stamping
     * Screen Printing
     * Printed Polyester Film
     * Embossing
     * Ink Plotting
     * Plasma Treatment
 * Microfluidics News


SIMPLE MICROFLUIDICS


EVERYTHING YOU WANT TO KNOW ABOUT MICROFLUIDICS MANUFACTURING

Become the microfluidics fabrication expert at your lab




PDMS MICROFLUIDICS MOLDING

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 * Overview
 * What is PDMS?
 * 3D Printed Mold
 * Metal Micromilling
 * Puffy Paint Mold
 * Duplicate a PDMS circuit
 * ABS sheet mold
 * ESCARGOT


DUPLICATE A CHIP

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 * How to duplicate a microfluidic chip


PAPER MICROFLUIDIC FABRICATION

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 * Overview
 * Laser Cutting
 * Wax Printing
 * Wax Stamping
 * Wax Tracing
 * Movable Type Wax Printing
 * Paper and Tape
 * Stamp Printing Ink
 * Stamp Printing PDMS
 * Flash Foam Stamping
 * Screen Printing
 * Laser Printed Polyester Film
 * Embossing
 * Ink Plotting
 * Plasma Treatment
 * Silicon-Oxide Layer (UV/Ozone Treatment)


PDMS SURFACE MODIFICATION

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 * SolGel (TEOS)
 * SolGel (Glass)
 * SolGel (Borosilicate glass)
 * O2 Plasma (Plasma Cleaner)
 * O2 Plasma (Microwave)
 * Surfactant in-molding
 * PEGMEM Modification
 * PVA Deposition
 * PVP Coating
 * Silinization
 * Chemical Micropatterning
 * Polymer Brushing (grafting-to)
 * Polymer Brushing (grafting-from)
 * Charged Polymers


WHY MICROFLUIDICS?



> We all know about the miracle of miniaturization. Back in the day, computers
> used to fill this entire room, and people actually used to work inside the
> computers. [..] The good news is that the same technology that allowed
> miniaturization of electronics is now allowing us to miniaturize biological
> laboratories. So, right now, we can actually miniaturize biological and
> chemistry laboratories onto microfluidic chips [..] so you have integrated
> valves, pumps, mixers and injectors — so you can fit entire diagnostic
> experiments onto a microfluidic system.
> 
> Fredrick Balagadde, UMass Lowell



> By combining tissue engineering techniques with microfluidics, the field is
> actually evolving towards just that, a model of the entire ecosystem of the
> body, complete with multiple organ systems to be able to test how a drug you
> might take for your blood pressure might affect your liver or an
> antidepressant might affect your heart. These systems are really hard to
> build, but we’re just starting to be able to get there, and so, watch out.
> 
> Nina Tandon, CEO @ EpiBone



> This could really revolutionize and be a game changer for not only the
> pharmaceutical industry, but a whole host of different industries, including
> the cosmetics industry. We can [..] test whether the ingredients in those
> products that you’re using are actually safe to put on your skin without the
> need for animal testing. We could test the safety of chemicals that we are
> exposed to on a daily basis in our environment, such as chemicals in regular
> household cleaners. We could also use the organs on chips for applications in
> bioterrorism or radiation exposure. We could use them to learn more about
> diseases such as ebola or other deadly diseases such as SARS.
> 
> Geraldine Hamilton, Wyss Institute Harvard





ADDITIONAL RESOURCES

 1. Greg Nordin: New Tools, New Possibilities – 3D Printing for Lab-on-a-Chip
 2. Fluigent: Microfluidics definitions and advantages
 3. Charles Baroud: Microfluidic based medical technologies of the future



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