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 2. Auckland Bioengineering Institute

 1. Our research
 2. Research groups and themes
 3. You are currently on: Implantable Devices Group


IMPLANTABLE DEVICES GROUP

Showcasing our research into implantable devices, their potential and how they
can be used to make a dramatic difference to people’s lives.


RESEARCH QUESTIONS

An electric heart pump can provide life support for heart failure. Today’s pumps
need a wire poking through the skin to provide enough power to keep the pump
spinning, and everyone gets infections from this wire.

The questions are:

 * Can we do better?
 * Can we eliminate drive-line infections using our wireless power transfer
   technology?

We have been looking at this and making developments at the University of
Auckland over the past 25 years.

We have been working on a pump that can be charged overnight so it can run all
day without cables and connections to support a patient’s natural heart. This
work is in conjunction with leading clinicians and pump companies in NZ and the
US.


PROJECTS


SMALL, POWER-EFFICIENT IMPLANTABLE MEDICAL DEVICES

The Implantable Devices Group has been developing small, power-efficient,
wireless data acquisition systems that can be implanted for long-term monitoring
of physiological signals.

A driving force has been our need to record sympathetic nerve activity which is
small in magnitude, high in frequency content and measurement durations of a
month are required.

Our solution to this problem is a compact device capable of recording a wide
variety of biopotential signals with bandwidths as high as 8 KHz. These devices
are now available through the Auckland-based company Kaha Sciences.


NEW SENSORS FOR BLOOD ANALYSIS, BLOOD FLOW AND BLOOD PRESSURE MONITORING

Our focus is on power and development of new sensors. Inductive power transfer
has been used to provide energy to an ECG telemetry system for a rat. New
sensors are being investigated for blood analysis, blood flow and blood
pressure.

These devices are low cost, high volume, and have applications in diverse areas
starting with the implantable animal monitoring market, moving into clinical
monitoring and also adding versatility to other existing devices.


OPTOGENETICS

This involves a custom-made implantable light module. Optogenetics uses light to
manipulate neural activity. This has several advantages over conventional
electrical stimulation approach including:

 * Specific cell-type targeting with precise temporal precision
 * Simultaneous stimulation using different wavelengths of light
 * Eliminating side effects associated with electrical stimulation.

Optogenetic stimulation offers the potential of treating lifetime conditions
such as Parkinson’s Disease. However, current optogenetics available
commercially are mainly connected with wires or fibres existing the body and
providing an infection risk and are generally not suitable for chronic use.

This study project is creating fully implantable optogenetics system supporting
long-term light stimulation. A custom-made LED-fibre light module has been
designed and validated to measure individual cellular response to optical
stimulation of photosensitive rat brain slices.


MITIGATING DRIFT

Long term error accumulation of pressure readings (termed drift) significantly
affects the operating lifetime of intracranial pressure monitors for
hydrocephalus.

When drift occurs the real and measured pressures differ, which becomes
clinically significant after some time.

Mitigating drift involves studying the contributions from raw pressure dies such
as inelastic mechanical deformation and thermal effects of wire bonding. It also
involves studying the effect of various encapsulation methods for water vapour
transmission and moisture absorption, where encapsulation is required for
biocompatibility and sensor protection.


MEMBERS


PRIMARY CONTACT

David Budgett



ACADEMICS

David Budgett
Beverly Chen
Robert Gallichan
Sarah-Jane Guild
Jenny Kruger
Simon Malpas
Dan McCormick



PROFESSIONALS

Dario Barron
Laith Hermez
Stepan Lapshev
Alex Leung
Bryon Wright



STUDENTS

Cyril (Shun Long) Au
Emma Ordono Evangelista
Mehak Janjua
Rui Jin
Dixon Leung
Hendrick Lim
Alistair Newcombe
Laura Pedofsky
Reza (Mohammad) Seh Dehi
Chaoping Zhang


Our people


FUNDING PARTNERS

The Implantable Devices Group gratefully acknowledges the support of its funding
partners:

 * Auckland UniServices Ltd
 * Pre-seed Accelerator Fund
 * Health Research Council of New Zealand
 * MBIE
 * Hugo Charitable Trust


INTERNATIONAL LINKS

 * Australia: Baker IDI Heart and Diabetes Institute and Bionics Institute
   Melbourne
 * US: Cedars-Sinai Cardiology and MIT, Boston





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