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Text Content

TRIS SAVINGS PROGRAM

 * IMPORTANT SAFETY INFORMATION
 * DYANAVEL XR PRESCRIBING INFORMATION AND MEDICATION GUIDE
 * QUILLIVANT XR PRESCRIBING INFORMATION AND MEDICATION GUIDE
 * QUILLICHEW ER PRESCRIBING INFORMATION AND MEDICATION GUIDE
 * DYANAVEL XR FOR HEALTHCARE PROFESSIONALS
 * QUILLIVANT XR QUILLICHEW ER FOR HEALTHCARE PROFESSIONALS

 * MENUX

 * * IMPORTANT SAFETY INFORMATION
   * DYANAVEL XR PRESCRIBINGINFORMATION AND MEDICATION GUIDE
   * QUILLIVANT XR PRESCRIBING INFORMATION AND MEDICATION GUIDE
   * QUILLICHEW ER PRESCRIBING INFORMATION AND MEDICATION GUIDE
   * DYANAVEL XR FOR HEALTHCAREPROFESSIONALS
   * QUILLIVANT XRQUILLICHEW ER FOR HEALTHCARE PROFESSIONALS


MENU

With the Tris Savings program, you may be eligible to save on your out-of-pocket
costs for Dyanavel XR, Quillivant XR, or QuilliChew ER

ELIGIBLE PATIENTS MAY
PAY AS LITTLE AS $20*
ON THEIR PRESCRIPTION
Get my savings card


*With the DYANAVEL XR, QUILLIVANT XR, or QUILLICHEW ER Savings Card, eligible
commercially-insured and cash-paying patients can lower their out-of-pocket
costs for their prescription. Eligible insured patients may pay as little as
$20, and the card pays up to the maximum benefit. Program benefit calculated on
FDA-approved dosing. Offer valid for up to 12 uses by 03/31/2022. A valid
Prescriber ID# is required on the prescription. Patients with questions about
the Tris Savings offer should call 1-888-840-7006.





APPROVED USE

Dyanavel XR (amphetamine), Quillivant XR (methylyphenidate hydrochloride), and
QuilliChew ER(methylyphenidate hydrochloride) are central nervous system (CNS)
stimulant prescription medicines used for the treatment of Attention Deficit
Hyperactivity Disorder (ADHD) in people 6 years and older. These medicines may
help increase attention and decrease impulsiveness and hyperactivity in people
with ADHD.

It is not known if Dyanavel XR, Quillivant XR, and QuilliChew ER are safe and
effective in children under 6 years of age.


IMPORTANT SAFETY INFORMATION

Dyanavel XR, Quillivant XR, and QuilliChew ER are federally controlled
substances (CII) because they can be abused or lead to dependence. Keep these
medicines in a safe place to prevent misuse and abuse. Selling or giving away
these medicines may harm others and is against the law. Tell your doctor if you,
your child, or any family members have ever abused or been dependent on alcohol,
prescription medicines, or street drugs.

Dyanavel XR, or Quillivant XR and QuilliChew ER, should not be taken if you or
your child are allergic to amphetamine or methylphenidate hydrochloride,
respectively, or any of the ingredients in these medicines, or are taking or
have taken within the past 14 days an anti-depression medicine called a
monoamine oxidase inhibitor or MAOI.

Dyanavel XR, Quillivant XR, and QuilliChew ER can cause serious side effects.
Tell the doctor:

 * if you or your child have heart problems, heart defects, high blood pressure,
   or a family history of these problems. This is important because sudden death
   has occurred in children 6 to 17 years old with heart problems or defects,
   and sudden death, stroke, and heart attack have happened in adults. Your
   doctor should check you or your child carefully for heart problems before
   starting any of these medicines. Since increases in blood pressure and heart
   rate may occur, the doctor should regularly check these during treatment.
   Call the doctor right away if you or your child have any signs of heart
   problems such as chest pain, shortness of breath, or fainting while taking
   any of these medicines.
 * if you or your child have mental problems, or a family history of suicide,
   bipolar illness, or depression. This is important because new or worsening
   behavior and thought problems or bipolar illness may occur. New symptoms such
   as seeing or hearing things that are not real, believing things that are not
   true, being suspicious, or having new manic symptoms may occur. Call the
   doctor right away if there are any new or worsening mental symptoms during
   treatment.
 * if you or your child have circulation problems in fingers and toes (called
   peripheral vasculopathy, including Raynaud’s phenomenon). Fingers or toes may
   feel numb, cool, painful, sensitive to temperature, and/or change color from
   pale, to blue, to red. Call the doctor right away if any signs of unexplained
   wounds appear on fingers or toes while taking Dyanavel XR, Quillivant XR, or
   QuilliChew ER.
 * if your child is having slowing of growth (height and weight); Your child
   should have his or her height and weight checked often while taking Dyanavel
   XR, Quillivant XR, or QuilliChew ER.
 * if you or your child develop painful and prolonged erections (priapism), seek
   medical help right away. Priapism has occurred with methylphenidate
   (Quillivant XR and QuilliChew ER). Because priapism can cause long-lasting
   damage, it should be checked by a doctor right away.
 * if you or your child have symptoms of serotonin syndrome - agitation,
   hallucinations, coma, or other changes in mental status; fast heartbeat;
   sweating or fever; nausea, vomiting, diarrhea; high or low blood pressure;
   problems controlling movements or muscle twitching; muscle stiffness or
   tightness. Serotonin syndrome may occur when Dyanavel XR is taken with
   certain other medicines and may be life-threatening. Stop Dyanavel XR and
   call your doctor or go to the nearest hospital emergency room.
 * if you or your child have phenylketonuria (PKU). QuilliChew ER contains
   phenylalanine as part of theartificial sweetener, aspartame. The artificial
   sweetener may be harmful to people with PKU or who are allergic to
   phenylalanine.
 * if you or your child are pregnant or plan to become pregnant. It is not known
   if Dyanavel XR, Quillivant XR, or QuilliChew ER will harm your unborn baby.
   Tell your doctor if you or your child become pregnant during treatment with
   any of these medicines.
 * if you or your child is breastfeeding or plan to breastfeed. Dyanavel XR,
   Quillivant XR, and QuilliChew ER pass into breast milk. You or your child
   should not breastfeed while you are taking any of these medicines.

Common side effects of amphetamine products include:

 * dry mouth
 * decreased appetite

 * weight loss
 * stomach pain
 * nausea

 * trouble sleeping
 * restlessness
 * extreme mood changes

 * dizziness
 * increased heart rate

 * dry mouth
 * decreased appetite
 * weight loss
 * stomach pain
 * nausea

 * trouble sleeping
 * restlessness
 * extreme mood changes
 * dizziness
 * increased heart rate

Common side effects of methylphenidate products include:

 * decreased appetite
 * trouble sleeping
 * nausea
 * vomiting

 * indigestion
 * stomach pain
 * weight loss

 * anxiety
 * dizziness
 * irritability

 * mood swings
 * fast heart beat
 * increased blood pressure

 * decreased appetite
 * trouble sleeping
 * nausea
 * vomiting
 * indigestion
 * stomach pain
 * weight loss

 * anxiety
 * dizziness
 * irritability
 * mood swings
 * fast heart beat
 * increased blood pressure

Talk to your doctor if you or your child have any side effects that bother you
or do not go away.

Avoid drinking alcohol while taking Dyanavel XR, Quillivant XR, or QuilliChew
ER.

You are encouraged to report negative side effects of prescription drugs to the
FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Please see Full Prescribing Information and Medication Guide for Dyanavel XR,
Quillivant XR, and QuilliChew ER, including Boxed Warning about Abuse and
Dependence.

The health information contained herein is provided for educational purposes
only and is not intended to replace discussions with a healthcare professional.
All decisions regarding patient care must be made with a healthcare
professional, considering the unique characteristics of the patient.

This site is intended solely for US residents and is governed solely by US laws
and government regulations. Please see our online privacy policy for more
information. While Tris Pharma makes reasonable efforts to include accurate,
up-to-date information on the site, Tris Pharma makes no warranties or
representations as to its accuracy. Tris Pharma assumes no liability for any
errors or omissions in the content of the site.

DYANAVEL XR is a registered trademark of Tris Pharma, Inc. Quillivant XR and
QuilliChew ER are registered trademarks of NextWave Pharmaceuticals, Inc. © 2021
Tris Pharma, Inc. All rights reserved. DXR.773.PR      01/21






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