kromatid.com Open in urlscan Pro
141.193.213.20  Public Scan

Submitted URL: https://t.sidekickopen14.com/Ctc/OO+23284/cyDwT04/Jks2-6q7W69sMD-6lZ3n-W6DSBwf6HvLwgF8r_-KCNTM6N587X8Wml1STW8SLWPF6vvjpRN3xZt...
Effective URL: https://kromatid.com/genetic-disease-services/
Submission: On March 10 via manual from US — Scanned from DE

Form analysis 6 forms found in the DOM

Name: loginformPOST https://kromatid.com/wp-login.php?wpe-login=true

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GET https://kromatid.com/

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</form>

GET https://kromatid.com/

<form role="search" class="searchform fusion-search-form  fusion-search-form-clean" method="get" action="https://kromatid.com/" data-hs-cf-bound="true">
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GET https://kromatid.com/

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      <input type="submit" class="fusion-search-submit searchsubmit" aria-label="Search" value="">
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</form>

POST /genetic-disease-services/

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    <div id="wpforms-10224-field_9-container" class="wpforms-field wpforms-field-text" data-field-id="9"><label class="wpforms-field-label" for="wpforms-10224-field_9">Institution <span class="wpforms-required-label">*</span></label><input
        type="text" id="wpforms-10224-field_9" class="wpforms-field-medium wpforms-field-required" name="wpforms[fields][9]" required=""></div>
    <div id="wpforms-10224-field_1-container" class="wpforms-field wpforms-field-email" data-field-id="1"><label class="wpforms-field-label" for="wpforms-10224-field_1">Professional Email <span class="wpforms-required-label">*</span></label><input
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    <div id="wpforms-10224-field_7-container" class="wpforms-field wpforms-field-text" data-field-id="7"><label class="wpforms-field-label" for="wpforms-10224-field_7">Sample Type</label><input type="text" id="wpforms-10224-field_7"
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    <div id="wpforms-10224-field_5-container" class="wpforms-field wpforms-field-text" data-field-id="5"><label class="wpforms-field-label" for="wpforms-10224-field_5">Cell Type</label><input type="text" id="wpforms-10224-field_5"
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    <div id="wpforms-10224-field_10-container" class="wpforms-field wpforms-field-radio" data-field-id="10"><label class="wpforms-field-label" for="wpforms-10224-field_10">Number of Cells Analyzed Per Sample</label>
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    <div id="wpforms-10224-field_8-container" class="wpforms-field wpforms-field-textarea" data-field-id="8"><label class="wpforms-field-label" for="wpforms-10224-field_8">Experimental Objective</label><textarea id="wpforms-10224-field_8"
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  <div class="wpforms-field wpforms-field-hp"><label for="wpforms-10224-field-hp" class="wpforms-field-label">Comment</label><input type="text" name="wpforms[hp]" id="wpforms-10224-field-hp" class="wpforms-field-medium"></div>
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</form>

GET https://kromatid.com/

<form role="search" class="searchform fusion-search-form  fusion-search-form-clean" method="get" action="https://kromatid.com/" data-hs-cf-bound="true">
  <div class="fusion-search-form-content">
    <div class="fusion-search-field search-field">
      <label><span class="screen-reader-text">Search for:</span>
        <input type="search" value="" name="s" class="s" placeholder="Search..." required="" aria-required="true" aria-label="Search...">
      </label>
    </div>
    <div class="fusion-search-button search-button">
      <input type="submit" class="fusion-search-submit searchsubmit" aria-label="Search" value="">
    </div>
  </div>
</form>

Text Content

Skip to content
 * Cart
 * My Account
   
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 * Cart

 * Cart
 * My Account
 * Cart


Search for:


 * PRODUCTS
    * FISH PROBES
      * HUMAN WHOLE CHROMOSOME PINPOINT FISH™ PAINT PROBES
      * SUBCENTROMERE PINPOINT FISH™ PROBES
      * SUBTELOMERE PINPOINT FISH™ PROBES
      * ONCOLOGY PINPOINT FISH™ PROBES
    * FISH KITS
      * TP53/CEP17 PINPOINT FISH™ PROBE
    * DGH™ KITS
      * dGH™ in-Site™ CAR-T PROBE KIT
      * dGH™ ASSAYS CELL PREP
    * BUFFERS AND REAGENTS
   
   
 * SERVICES
    * PLASMID SERVICES
      * CUSTOM PLASMIDSNEW!
      * PLASMID PREPSNEW!
    * ASSAY SERVICES
      * dGH in-Site™ TARGETED ASSAY SERVICES
      * dGH SCREEN™ UNBIASED ASSAY SERVICES
      * PINPOINT FISH™ ASSAY SERVICES
    * RESEARCH SERVICES
      * CELL CULTURE SERVICES
      * G BANDING SERVICES
   
   
 * SUPPORT & FAQ’s
    * TECHNICAL INFORMATION
      * MICROSCOPE SPECIFICATIONS DATA SHEET
      * WATER BATH APPLICATION NOTES FOR PINPOINT FISH™ PROBES
      * MULTIPLEXING WITH PINPOINT FISH™ PROBES APPLICATION NOTES
      * FIRST TIME USERS APPLICATION NOTES FOR PINPOINT FISH™ PROBES
    * PRESENTATIONS & POSTERS
      * SCIENTIFIC PRESENTATIONS
      * POSTERS
    * FREQUENTLY ASKED QUESTIONS
   
   
 * ABOUT KROMATID
   * dGH™ TECHNOLOGY
   * WHO WE ARE
   * CAREERS
   * BLOG
   * KROMATID NEWS
 * dGH™ WEBINAR
 * PROJECT INQUIRY
 * 

Search for:


 * PRODUCTS
    * FISH PROBES
      * HUMAN WHOLE CHROMOSOME PINPOINT FISH™ PAINT PROBES
      * SUBCENTROMERE PINPOINT FISH™ PROBES
      * SUBTELOMERE PINPOINT FISH™ PROBES
      * ONCOLOGY PINPOINT FISH™ PROBES
    * FISH KITS
      * TP53/CEP17 PINPOINT FISH™ PROBE
    * DGH™ KITS
      * dGH™ in-Site™ CAR-T PROBE KIT
      * dGH™ ASSAYS CELL PREP
    * BUFFERS AND REAGENTS
   
   
 * SERVICES
    * PLASMID SERVICES
      * CUSTOM PLASMIDSNEW!
      * PLASMID PREPSNEW!
    * ASSAY SERVICES
      * dGH in-Site™ TARGETED ASSAY SERVICES
      * dGH SCREEN™ UNBIASED ASSAY SERVICES
      * PINPOINT FISH™ ASSAY SERVICES
    * RESEARCH SERVICES
      * CELL CULTURE SERVICES
      * G BANDING SERVICES
   
   
 * SUPPORT & FAQ’s
    * TECHNICAL INFORMATION
      * MICROSCOPE SPECIFICATIONS DATA SHEET
      * WATER BATH APPLICATION NOTES FOR PINPOINT FISH™ PROBES
      * MULTIPLEXING WITH PINPOINT FISH™ PROBES APPLICATION NOTES
      * FIRST TIME USERS APPLICATION NOTES FOR PINPOINT FISH™ PROBES
    * PRESENTATIONS & POSTERS
      * SCIENTIFIC PRESENTATIONS
      * POSTERS
    * FREQUENTLY ASKED QUESTIONS
   
   
 * ABOUT KROMATID
   * dGH™ TECHNOLOGY
   * WHO WE ARE
   * CAREERS
   * BLOG
   * KROMATID NEWS
 * dGH™ WEBINAR
 * PROJECT INQUIRY
 * 

 * PRODUCTS
    * FISH PROBES
      * HUMAN WHOLE CHROMOSOME PINPOINT FISH™ PAINT PROBES
      * SUBCENTROMERE PINPOINT FISH™ PROBES
      * SUBTELOMERE PINPOINT FISH™ PROBES
      * ONCOLOGY PINPOINT FISH™ PROBES
    * FISH KITS
      * TP53/CEP17 PINPOINT FISH™ PROBE
    * DGH™ KITS
      * dGH™ in-Site™ CAR-T PROBE KIT
      * dGH™ ASSAYS CELL PREP
    * BUFFERS AND REAGENTS
   
   
 * SERVICES
    * PLASMID SERVICES
      * CUSTOM PLASMIDSNEW!
      * PLASMID PREPSNEW!
    * ASSAY SERVICES
      * dGH in-Site™ TARGETED ASSAY SERVICES
      * dGH SCREEN™ UNBIASED ASSAY SERVICES
      * PINPOINT FISH™ ASSAY SERVICES
    * RESEARCH SERVICES
      * CELL CULTURE SERVICES
      * G BANDING SERVICES
   
   
 * SUPPORT & FAQ’s
    * TECHNICAL INFORMATION
      * MICROSCOPE SPECIFICATIONS DATA SHEET
      * WATER BATH APPLICATION NOTES FOR PINPOINT FISH™ PROBES
      * MULTIPLEXING WITH PINPOINT FISH™ PROBES APPLICATION NOTES
      * FIRST TIME USERS APPLICATION NOTES FOR PINPOINT FISH™ PROBES
    * PRESENTATIONS & POSTERS
      * SCIENTIFIC PRESENTATIONS
      * POSTERS
    * FREQUENTLY ASKED QUESTIONS
   
   
 * ABOUT KROMATID
   * dGH™ TECHNOLOGY
   * WHO WE ARE
   * CAREERS
   * BLOG
   * KROMATID NEWS
 * dGH™ WEBINAR
 * PROJECT INQUIRY


 * PRODUCTS
   * FISH PROBES
     * HUMAN WHOLE CHROMOSOME PINPOINT FISH™ PAINT PROBES
     * SUBCENTROMERE PINPOINT FISH™ PROBES
     * SUBTELOMERE PINPOINT FISH™ PROBES
     * ONCOLOGY PINPOINT FISH™ PROBES
   * FISH KITS
     * TP53/CEP17 PINPOINT FISH™ PROBE
   * DGH™ KITS
     * dGH™ in-Site™ CAR-T PROBE KIT
     * dGH™ ASSAYS CELL PREP
   * BUFFERS AND REAGENTS
 * SERVICES
   * PLASMID SERVICES
     * CUSTOM PLASMIDSNEW!
     * PLASMID PREPSNEW!
   * ASSAY SERVICES
     * dGH in-Site™ TARGETED ASSAY SERVICES
     * dGH SCREEN™ UNBIASED ASSAY SERVICES
     * PINPOINT FISH™ ASSAY SERVICES
   * RESEARCH SERVICES
     * CELL CULTURE SERVICES
     * G BANDING SERVICES
 * SUPPORT & FAQ’s
   * TECHNICAL INFORMATION
     * MICROSCOPE SPECIFICATIONS DATA SHEET
     * WATER BATH APPLICATION NOTES FOR PINPOINT FISH™ PROBES
     * MULTIPLEXING WITH PINPOINT FISH™ PROBES APPLICATION NOTES
     * FIRST TIME USERS APPLICATION NOTES FOR PINPOINT FISH™ PROBES
   * PRESENTATIONS & POSTERS
     * SCIENTIFIC PRESENTATIONS
     * POSTERS
   * FREQUENTLY ASKED QUESTIONS
 * ABOUT KROMATID
   * dGH™ TECHNOLOGY
   * WHO WE ARE
   * CAREERS
   * BLOG
   * KROMATID NEWS
 * dGH™ WEBINAR
 * PROJECT INQUIRY

 * PRODUCTS
   * FISH PROBES
     * HUMAN WHOLE CHROMOSOME PINPOINT FISH™ PAINT PROBES
     * SUBCENTROMERE PINPOINT FISH™ PROBES
     * SUBTELOMERE PINPOINT FISH™ PROBES
     * ONCOLOGY PINPOINT FISH™ PROBES
   * FISH KITS
     * TP53/CEP17 PINPOINT FISH™ PROBE
   * DGH™ KITS
     * dGH™ in-Site™ CAR-T PROBE KIT
     * dGH™ ASSAYS CELL PREP
   * BUFFERS AND REAGENTS
 * SERVICES
   * PLASMID SERVICES
     * CUSTOM PLASMIDSNEW!
     * PLASMID PREPSNEW!
   * ASSAY SERVICES
     * dGH in-Site™ TARGETED ASSAY SERVICES
     * dGH SCREEN™ UNBIASED ASSAY SERVICES
     * PINPOINT FISH™ ASSAY SERVICES
   * RESEARCH SERVICES
     * CELL CULTURE SERVICES
     * G BANDING SERVICES
 * SUPPORT & FAQ’s
   * TECHNICAL INFORMATION
     * MICROSCOPE SPECIFICATIONS DATA SHEET
     * WATER BATH APPLICATION NOTES FOR PINPOINT FISH™ PROBES
     * MULTIPLEXING WITH PINPOINT FISH™ PROBES APPLICATION NOTES
     * FIRST TIME USERS APPLICATION NOTES FOR PINPOINT FISH™ PROBES
   * PRESENTATIONS & POSTERS
     * SCIENTIFIC PRESENTATIONS
     * POSTERS
   * FREQUENTLY ASKED QUESTIONS
 * ABOUT KROMATID
   * dGH™ TECHNOLOGY
   * WHO WE ARE
   * CAREERS
   * BLOG
   * KROMATID NEWS
 * dGH™ WEBINAR
 * PROJECT INQUIRY


Search for:



Genetic Disease ServicesDave Burdick2023-02-22T08:36:21-07:00



MONITOR STRUCTURAL VARIANTS AND GENOMIC STABILITY WITH DGH SCREEN™ ASSAYS




DGH SCREEN™ IS A SINGLE-CELL ASSAY DESIGNED TO MONITOR STRUCTURAL VARIANTS
THROUGHOUT THE GENOME. THE ASSAY USES PATENTED DIRECTIONAL GENOMIC
HYBRIDIZATION™ (DGH™) TECHNOLOGY COMBINED WITH MULTIPLEX FLUORESCENCE LABELING
TO TRACK AND LOCALIZE A WIDE VARIETY OF CHROMOSOMAL REARRANGEMENTS WITH A LIMIT
OF DETECTION AS LOW AS 5KB.  



Overview of dGH SCREEN™ Assay Services:

 * Detection of exchange events including reciprocal, balanced and allelic
   translocations; orientation events like inversions and sister chromatid
   exchanges; 
 * Chromosomal gain and loss events including sister chromatid fusions,
   dicentrics/acentrics, fragmentation/chromothrypsis, polypoidy and aneuploidy.
 * Cellular engineering outcomes: genome-wide, cell-by-cell and
   chromosome-by-chromosome assessment of structure, pre- and post-modification;
 * Orthogonal data for sequencing: genome-wide, confirmatory data regarding
   rearrangements predicted with long read and other NGS analyses;
 * Structural integrity QC: a straightforward yardstick by which to measure the
   relative stability of cell lines, or to screen and compare candidate cell
   lines, based on total genomic structural variation metrics; 
 * Genomic stability assessment: Track persistence of variants over time,
   passages and process variable changes;
 * Variant discovery: discover previously unknown mutations by de novo
   assessment of single cells from patient sub-types. 

dGH SCREEN™ analysis produces the kinds of rearrangement data needed to create
stability and structural variance profiles for complex, heterogeneous cell
populations.  

This makes dGH SCREEN™ one of the most comprehensive and robust karyographic
assays available. 



 * 1/5 - DATA FROM 6 UNDIAGNOSED DISEASE PATIENTS AND 5 OF THEIR FAMILY MEMBERS
   WERE ASSESSED WITH DGH PAINTS THROUGH THE UNDIAGNOSED DISEASE CONSORTIUM.
   HERE, A CELL FROM ONE OF THE PATIENTS DEMONSTRATES A PERICENTRIC INVERSION ON
   CHROMOSOME 2 (CIRCLED).
   
   

 * 2/5 - A CELL FROM ANOTHER PATIENT FROM THE UNDIAGNOSED DISEASE CONSORTIUM
   DEMONSTRATING A PARACENTRIC INVERSION ON CHROMOSOME 2 (CIRCLED).
   
   

 * 3/5 - DE NOVO DISCOVERY OF A PREVIOUSLY UNSUSPECTED LARGE INVERSION (CIRCLED)
   FOUND IN ROUGHLY 40% OF CELLS ON CHROMOSOME 2 IN AN UNDIAGNOSED DISEASE
   PATIENT.
   
   

 * 4/5 - FOLLOW UP ASSAY IN WHICH A PROBE LADDER WAS DESIGNED FOR THE ANTISENSE
   STRAND, AND USED IN COMBINATION WITH CHROMATID 2 PAINT TO NARROW DOWN THE
   BREAKPOINT REGION LOCATIONS. THIS IMAGE DEMONSTRATES A NORMAL CELL WITHOUT
   REARRANGEMENTS.
   
   

 * 5/5 - ANTISENSE LADDER AND CHROMATID 2 PAINT COMBINATION ASSAY DEMONSTRATING
   AN INVERSION BETWEEN THE LADDER AND PAINT (CIRCLED).
   
   

 * 
 * 




ORDERING INFORMATION

SKU

PRODUCTS

LIST PRICE

SCR-001 SCREEN Adherent/Suspension Culture Development: Thaw, recovery, and
harvest optimization $1,500.00 SCR-002 SCREEN Assay Execution and Analysis:
Imaging and scoring for 50 spreads/sample $5,775.00 SCR-003 SCREEN Assay
Execution and Analysis: Imaging and scoring for 20 spreads/sample $3,465.00
SCR-004 SCREEN Assay Execution and Analysis: Imaging and scoring for 100
spreads/sample $10,395.00 SCR-005 SCREEN T-Cell Culture Development: Thaw,
recovery, and harvest optimization $1,625.00 SCR-006 SCREEN IPSC Cell Culture
Development: Thaw, recovery, and harvest optimization $1,750.00 SCR-007 SCREEN
Whole Blood Culture Development: Thaw, recovery, and harvest optimization
$1,250.00 SCR-008 SCREEN Metaphase Adherent/Suspension Prep and Harvest
$1,500.00 SCR-009 SCREEN T Cells Metaphase Prep and Harvest $1,625.00 SCR-010
SCREEN™ IPSC Metaphase Prep and Harvest $1,750.00 SCR-011 SCREEN™ Whole Blood
Metaphase Prep and Harvest $1,250.00 SCR-012 SCREEN™ Chr1p E-Banding
mini-Analysis on 100 existing cells $,1050.00 SCR-013 SCREEN™ NK Cells Metaphase
Prep and Harvest $1,625.00 SCR-014 SCREEN™ NK Cell Culture Development: Thaw,
recovery, and harvest optimization $1,625.00




PLEASE FILL OUT THE FORM BELOW TO INQUIRE ABOUT DGH SCREEN™ ASSAYS

Please enable JavaScript in your browser to complete this form.
Name *
First
Last
Institution *
Professional Email *
Sample Type
Cell Type
Number of Cells Analyzed Per Sample
 * 20
 * 50
 * 100
 * Other

Experimental Objective
Expected Turnaround Time Needed
Any Additional Information You Would Like to Provide
Comment

Submit


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RESOURCES



Buffers and Reagents

DGH SCREEN™ DATASHEET

DGH SCREEN™ Assay Services Overview



DATASHEETS



Geno Toxicity and Genomic Instability Datasheet

Microscope Assay Specifications datasheet



SAMPLE DATA REPORTS



dGH SCREEN™ Sample Report

Sample Gene Editing Report



FISH PROBES AND SERVICES



Centromere Pinpoint FISH™ Probes

subTelomere Pinpoint FISH™ Probes

ONCOLOGY PINPOINT FISH™ PROBES

PINPOINT FISH™ TP53/CEP17 KIT

HUMAN WHOLE CHROMOSOME PINPOINT FISH™ PAINT PROBES

PINPOINT FISH™ ASSAY SERVICES



GENOMIC ASSAY PRODUCTS AND SERVICES



dGH™ CELL PREP KIT

DGH SCREEN™ UNBIASED ASSAY SERVICES

DGH IN-SITE™ TARGETED ASSAY SERVICES


RESEARCH SERVICES


Cell Culture Services

G-Banding






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Longmont, CO 80501

Phone: 720-815-2898
Fax: 720-815-2902


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