kromatid.com
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141.193.213.20
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Submitted URL: https://t.sidekickopen14.com/Ctc/OO+23284/cyDwT04/Jks2-6q7W69sMD-6lZ3n-W6DSBwf6HvLwgF8r_-KCNTM6N587X8Wml1STW8SLWPF6vvjpRN3xZt...
Effective URL: https://kromatid.com/genetic-disease-services/
Submission: On March 10 via manual from US — Scanned from DE
Effective URL: https://kromatid.com/genetic-disease-services/
Submission: On March 10 via manual from US — Scanned from DE
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Text Content
Skip to content * Cart * My Account Remember Me Register * Cart * Cart * My Account * Cart Search for: * PRODUCTS * FISH PROBES * HUMAN WHOLE CHROMOSOME PINPOINT FISH™ PAINT PROBES * SUBCENTROMERE PINPOINT FISH™ PROBES * SUBTELOMERE PINPOINT FISH™ PROBES * ONCOLOGY PINPOINT FISH™ PROBES * FISH KITS * TP53/CEP17 PINPOINT FISH™ PROBE * DGH™ KITS * dGH™ in-Site™ CAR-T PROBE KIT * dGH™ ASSAYS CELL PREP * BUFFERS AND REAGENTS * SERVICES * PLASMID SERVICES * CUSTOM PLASMIDSNEW! * PLASMID PREPSNEW! * ASSAY SERVICES * dGH in-Site™ TARGETED ASSAY SERVICES * dGH SCREEN™ UNBIASED ASSAY SERVICES * PINPOINT FISH™ ASSAY SERVICES * RESEARCH SERVICES * CELL CULTURE SERVICES * G BANDING SERVICES * SUPPORT & FAQ’s * TECHNICAL INFORMATION * MICROSCOPE SPECIFICATIONS DATA SHEET * WATER BATH APPLICATION NOTES FOR PINPOINT FISH™ PROBES * MULTIPLEXING WITH PINPOINT FISH™ PROBES APPLICATION NOTES * FIRST TIME USERS APPLICATION NOTES FOR PINPOINT FISH™ PROBES * PRESENTATIONS & POSTERS * SCIENTIFIC PRESENTATIONS * POSTERS * FREQUENTLY ASKED QUESTIONS * ABOUT KROMATID * dGH™ TECHNOLOGY * WHO WE ARE * CAREERS * BLOG * KROMATID NEWS * dGH™ WEBINAR * PROJECT INQUIRY * Search for: * PRODUCTS * FISH PROBES * HUMAN WHOLE CHROMOSOME PINPOINT FISH™ PAINT PROBES * SUBCENTROMERE PINPOINT FISH™ PROBES * SUBTELOMERE PINPOINT FISH™ PROBES * ONCOLOGY PINPOINT FISH™ PROBES * FISH KITS * TP53/CEP17 PINPOINT FISH™ PROBE * DGH™ KITS * dGH™ in-Site™ CAR-T PROBE KIT * dGH™ ASSAYS CELL PREP * BUFFERS AND REAGENTS * SERVICES * PLASMID SERVICES * CUSTOM PLASMIDSNEW! * PLASMID PREPSNEW! * ASSAY SERVICES * dGH in-Site™ TARGETED ASSAY SERVICES * dGH SCREEN™ UNBIASED ASSAY SERVICES * PINPOINT FISH™ ASSAY SERVICES * RESEARCH SERVICES * CELL CULTURE SERVICES * G BANDING SERVICES * SUPPORT & FAQ’s * TECHNICAL INFORMATION * MICROSCOPE SPECIFICATIONS DATA SHEET * WATER BATH APPLICATION NOTES FOR PINPOINT FISH™ PROBES * MULTIPLEXING WITH PINPOINT FISH™ PROBES APPLICATION NOTES * FIRST TIME USERS APPLICATION NOTES FOR PINPOINT FISH™ PROBES * PRESENTATIONS & POSTERS * SCIENTIFIC PRESENTATIONS * POSTERS * FREQUENTLY ASKED QUESTIONS * ABOUT KROMATID * dGH™ TECHNOLOGY * WHO WE ARE * CAREERS * BLOG * KROMATID NEWS * dGH™ WEBINAR * PROJECT INQUIRY * * PRODUCTS * FISH PROBES * HUMAN WHOLE CHROMOSOME PINPOINT FISH™ PAINT PROBES * SUBCENTROMERE PINPOINT FISH™ PROBES * SUBTELOMERE PINPOINT FISH™ PROBES * ONCOLOGY PINPOINT FISH™ PROBES * FISH KITS * TP53/CEP17 PINPOINT FISH™ PROBE * DGH™ KITS * dGH™ in-Site™ CAR-T PROBE KIT * dGH™ ASSAYS CELL PREP * BUFFERS AND REAGENTS * SERVICES * PLASMID SERVICES * CUSTOM PLASMIDSNEW! * PLASMID PREPSNEW! * ASSAY SERVICES * dGH in-Site™ TARGETED ASSAY SERVICES * dGH SCREEN™ UNBIASED ASSAY SERVICES * PINPOINT FISH™ ASSAY SERVICES * RESEARCH SERVICES * CELL CULTURE SERVICES * G BANDING SERVICES * SUPPORT & FAQ’s * TECHNICAL INFORMATION * MICROSCOPE SPECIFICATIONS DATA SHEET * WATER BATH APPLICATION NOTES FOR PINPOINT FISH™ PROBES * MULTIPLEXING WITH PINPOINT FISH™ PROBES APPLICATION NOTES * FIRST TIME USERS APPLICATION NOTES FOR PINPOINT FISH™ PROBES * PRESENTATIONS & POSTERS * SCIENTIFIC PRESENTATIONS * POSTERS * FREQUENTLY ASKED QUESTIONS * ABOUT KROMATID * dGH™ TECHNOLOGY * WHO WE ARE * CAREERS * BLOG * KROMATID NEWS * dGH™ WEBINAR * PROJECT INQUIRY * PRODUCTS * FISH PROBES * HUMAN WHOLE CHROMOSOME PINPOINT FISH™ PAINT PROBES * SUBCENTROMERE PINPOINT FISH™ PROBES * SUBTELOMERE PINPOINT FISH™ PROBES * ONCOLOGY PINPOINT FISH™ PROBES * FISH KITS * TP53/CEP17 PINPOINT FISH™ PROBE * DGH™ KITS * dGH™ in-Site™ CAR-T PROBE KIT * dGH™ ASSAYS CELL PREP * BUFFERS AND REAGENTS * SERVICES * PLASMID SERVICES * CUSTOM PLASMIDSNEW! * PLASMID PREPSNEW! * ASSAY SERVICES * dGH in-Site™ TARGETED ASSAY SERVICES * dGH SCREEN™ UNBIASED ASSAY SERVICES * PINPOINT FISH™ ASSAY SERVICES * RESEARCH SERVICES * CELL CULTURE SERVICES * G BANDING SERVICES * SUPPORT & FAQ’s * TECHNICAL INFORMATION * MICROSCOPE SPECIFICATIONS DATA SHEET * WATER BATH APPLICATION NOTES FOR PINPOINT FISH™ PROBES * MULTIPLEXING WITH PINPOINT FISH™ PROBES APPLICATION NOTES * FIRST TIME USERS APPLICATION NOTES FOR PINPOINT FISH™ PROBES * PRESENTATIONS & POSTERS * SCIENTIFIC PRESENTATIONS * POSTERS * FREQUENTLY ASKED QUESTIONS * ABOUT KROMATID * dGH™ TECHNOLOGY * WHO WE ARE * CAREERS * BLOG * KROMATID NEWS * dGH™ WEBINAR * PROJECT INQUIRY * PRODUCTS * FISH PROBES * HUMAN WHOLE CHROMOSOME PINPOINT FISH™ PAINT PROBES * SUBCENTROMERE PINPOINT FISH™ PROBES * SUBTELOMERE PINPOINT FISH™ PROBES * ONCOLOGY PINPOINT FISH™ PROBES * FISH KITS * TP53/CEP17 PINPOINT FISH™ PROBE * DGH™ KITS * dGH™ in-Site™ CAR-T PROBE KIT * dGH™ ASSAYS CELL PREP * BUFFERS AND REAGENTS * SERVICES * PLASMID SERVICES * CUSTOM PLASMIDSNEW! * PLASMID PREPSNEW! * ASSAY SERVICES * dGH in-Site™ TARGETED ASSAY SERVICES * dGH SCREEN™ UNBIASED ASSAY SERVICES * PINPOINT FISH™ ASSAY SERVICES * RESEARCH SERVICES * CELL CULTURE SERVICES * G BANDING SERVICES * SUPPORT & FAQ’s * TECHNICAL INFORMATION * MICROSCOPE SPECIFICATIONS DATA SHEET * WATER BATH APPLICATION NOTES FOR PINPOINT FISH™ PROBES * MULTIPLEXING WITH PINPOINT FISH™ PROBES APPLICATION NOTES * FIRST TIME USERS APPLICATION NOTES FOR PINPOINT FISH™ PROBES * PRESENTATIONS & POSTERS * SCIENTIFIC PRESENTATIONS * POSTERS * FREQUENTLY ASKED QUESTIONS * ABOUT KROMATID * dGH™ TECHNOLOGY * WHO WE ARE * CAREERS * BLOG * KROMATID NEWS * dGH™ WEBINAR * PROJECT INQUIRY Search for: Genetic Disease ServicesDave Burdick2023-02-22T08:36:21-07:00 MONITOR STRUCTURAL VARIANTS AND GENOMIC STABILITY WITH DGH SCREEN™ ASSAYS DGH SCREEN™ IS A SINGLE-CELL ASSAY DESIGNED TO MONITOR STRUCTURAL VARIANTS THROUGHOUT THE GENOME. THE ASSAY USES PATENTED DIRECTIONAL GENOMIC HYBRIDIZATION™ (DGH™) TECHNOLOGY COMBINED WITH MULTIPLEX FLUORESCENCE LABELING TO TRACK AND LOCALIZE A WIDE VARIETY OF CHROMOSOMAL REARRANGEMENTS WITH A LIMIT OF DETECTION AS LOW AS 5KB. Overview of dGH SCREEN™ Assay Services: * Detection of exchange events including reciprocal, balanced and allelic translocations; orientation events like inversions and sister chromatid exchanges; * Chromosomal gain and loss events including sister chromatid fusions, dicentrics/acentrics, fragmentation/chromothrypsis, polypoidy and aneuploidy. * Cellular engineering outcomes: genome-wide, cell-by-cell and chromosome-by-chromosome assessment of structure, pre- and post-modification; * Orthogonal data for sequencing: genome-wide, confirmatory data regarding rearrangements predicted with long read and other NGS analyses; * Structural integrity QC: a straightforward yardstick by which to measure the relative stability of cell lines, or to screen and compare candidate cell lines, based on total genomic structural variation metrics; * Genomic stability assessment: Track persistence of variants over time, passages and process variable changes; * Variant discovery: discover previously unknown mutations by de novo assessment of single cells from patient sub-types. dGH SCREEN™ analysis produces the kinds of rearrangement data needed to create stability and structural variance profiles for complex, heterogeneous cell populations. This makes dGH SCREEN™ one of the most comprehensive and robust karyographic assays available. * 1/5 - DATA FROM 6 UNDIAGNOSED DISEASE PATIENTS AND 5 OF THEIR FAMILY MEMBERS WERE ASSESSED WITH DGH PAINTS THROUGH THE UNDIAGNOSED DISEASE CONSORTIUM. HERE, A CELL FROM ONE OF THE PATIENTS DEMONSTRATES A PERICENTRIC INVERSION ON CHROMOSOME 2 (CIRCLED). * 2/5 - A CELL FROM ANOTHER PATIENT FROM THE UNDIAGNOSED DISEASE CONSORTIUM DEMONSTRATING A PARACENTRIC INVERSION ON CHROMOSOME 2 (CIRCLED). * 3/5 - DE NOVO DISCOVERY OF A PREVIOUSLY UNSUSPECTED LARGE INVERSION (CIRCLED) FOUND IN ROUGHLY 40% OF CELLS ON CHROMOSOME 2 IN AN UNDIAGNOSED DISEASE PATIENT. * 4/5 - FOLLOW UP ASSAY IN WHICH A PROBE LADDER WAS DESIGNED FOR THE ANTISENSE STRAND, AND USED IN COMBINATION WITH CHROMATID 2 PAINT TO NARROW DOWN THE BREAKPOINT REGION LOCATIONS. THIS IMAGE DEMONSTRATES A NORMAL CELL WITHOUT REARRANGEMENTS. * 5/5 - ANTISENSE LADDER AND CHROMATID 2 PAINT COMBINATION ASSAY DEMONSTRATING AN INVERSION BETWEEN THE LADDER AND PAINT (CIRCLED). * * ORDERING INFORMATION SKU PRODUCTS LIST PRICE SCR-001 SCREEN Adherent/Suspension Culture Development: Thaw, recovery, and harvest optimization $1,500.00 SCR-002 SCREEN Assay Execution and Analysis: Imaging and scoring for 50 spreads/sample $5,775.00 SCR-003 SCREEN Assay Execution and Analysis: Imaging and scoring for 20 spreads/sample $3,465.00 SCR-004 SCREEN Assay Execution and Analysis: Imaging and scoring for 100 spreads/sample $10,395.00 SCR-005 SCREEN T-Cell Culture Development: Thaw, recovery, and harvest optimization $1,625.00 SCR-006 SCREEN IPSC Cell Culture Development: Thaw, recovery, and harvest optimization $1,750.00 SCR-007 SCREEN Whole Blood Culture Development: Thaw, recovery, and harvest optimization $1,250.00 SCR-008 SCREEN Metaphase Adherent/Suspension Prep and Harvest $1,500.00 SCR-009 SCREEN T Cells Metaphase Prep and Harvest $1,625.00 SCR-010 SCREEN™ IPSC Metaphase Prep and Harvest $1,750.00 SCR-011 SCREEN™ Whole Blood Metaphase Prep and Harvest $1,250.00 SCR-012 SCREEN™ Chr1p E-Banding mini-Analysis on 100 existing cells $,1050.00 SCR-013 SCREEN™ NK Cells Metaphase Prep and Harvest $1,625.00 SCR-014 SCREEN™ NK Cell Culture Development: Thaw, recovery, and harvest optimization $1,625.00 PLEASE FILL OUT THE FORM BELOW TO INQUIRE ABOUT DGH SCREEN™ ASSAYS Please enable JavaScript in your browser to complete this form. Name * First Last Institution * Professional Email * Sample Type Cell Type Number of Cells Analyzed Per Sample * 20 * 50 * 100 * Other Experimental Objective Expected Turnaround Time Needed Any Additional Information You Would Like to Provide Comment Submit NEW OFFERING ORDER PLASMIDPROS PREP ORDER CUSTOM PLASMIDS ORDER DEMECOLCINE (COLCEMID™) RESOURCES Buffers and Reagents DGH SCREEN™ DATASHEET DGH SCREEN™ Assay Services Overview DATASHEETS Geno Toxicity and Genomic Instability Datasheet Microscope Assay Specifications datasheet SAMPLE DATA REPORTS dGH SCREEN™ Sample Report Sample Gene Editing Report FISH PROBES AND SERVICES Centromere Pinpoint FISH™ Probes subTelomere Pinpoint FISH™ Probes ONCOLOGY PINPOINT FISH™ PROBES PINPOINT FISH™ TP53/CEP17 KIT HUMAN WHOLE CHROMOSOME PINPOINT FISH™ PAINT PROBES PINPOINT FISH™ ASSAY SERVICES GENOMIC ASSAY PRODUCTS AND SERVICES dGH™ CELL PREP KIT DGH SCREEN™ UNBIASED ASSAY SERVICES DGH IN-SITE™ TARGETED ASSAY SERVICES RESEARCH SERVICES Cell Culture Services G-Banding Close product quick view× TITLE 1880 Industrial Circle Dr. Suite A Longmont, CO 80501 Phone: 720-815-2898 Fax: 720-815-2902 Search for: Terms of Sale Privacy Policy © 2023 KromaTiD Inc. 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