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Text Content

Zum Inhalt springen
LATEST NEWS

Björn Cochlovius New CEO of Eleva
...
Eleva Enters Clinical Development of Difficult-To-Express High-Potential
Proteins
...
Eleva Reaches Industrial Production Scale and Prepares for Clinical Development
of Factor H
...
Navigo Proteins and Eleva Announce Successful Development of an Affinity
Chromatography Resin Customized for the Efficient Purification of Human
Complement-Factor H
...
Eleva secures up to EUR 60 million to advance a drug candidate, appoints new
board member

UNLOCKING THE POWER
OF COMPLEX PROTEINS FOR
FUTURE THERAPIES

Toggle Navigation
 * Welcome
 * Assets
   * Complement
   * Enzyme replacement therapies
 * Platform
   * Publications
 * Company
   * Careers
 * Newsroom
 * Contact
   * Imprint
   * Privacy policy

Toggle Navigation
 * Welcome
 * Assets
   * Complement
   * Enzyme replacement therapies
 * Platform
   * Publications
 * Company
   * Careers
 * Newsroom
 * Contact
   * Imprint
   * Privacy policy


Welcome to elevaMarkus Reichert2023-10-24T14:42:55+02:00

MISSION


TOGETHER WITH PHARMACEUTICAL PARTNERS, WE DEVELOP DRUG CANDIDATES TO ADVANCE
INTO THE CLINIC

New solutions and new therapies need new avenues to reach them. The age of
cells producing biological compounds has achieved a lot for human medicine, but
its means are coming to an end. A step change in technology is required to
unleash the potential of molecules we didn’t dream we would discover – or be
able to create if we did.

ELEVA is opening this realm of unprecedented therapies with the help of
an inconspicuous but incredibly efficient tool: Bryophyta, more commonly known
as moss. This ancient organism holds the key to the therapies of the future.
Moss plants are not only able to produce the most complex and demanding
proteins; with their unique characteristics, they virtually invite easy, stable
engineering and reliable output.

WHAT WE OFFER


HOW ELEVA CAN CHANGE YOUR WORLD

We have harnessed the moss platform’s outstanding features to create candidates
and take them to clinical stages, ready for a bright future. Be our clinical
partner to develop unprecedented candidates into the therapies that will turn
around countless patient’s lives.

 * Are you looking for a partner with an asset that might be the key to a
   revolutionary treatment?

 * Are you struggling with a difficult protein?

 * Are you toying with a revolutionary toxin that targets just the right cells?

JOIN US AND OUR MOSS CELLS TO UNLEASH OPPORTUNITIES NEVER IMAGINED BEFORE, BASED
ON A PLATFORM THAT SURPASSES THE CAPACITIES OF ALL OTHER CELL LINES USED TO
DATE.

TALK TO US IF YOU ARE LOOKING AT PRODUCING

 * Antibodies

 * Biobetters

 * LSD enzymes

 * Fusion toxins

 * Virus-like particles/vaccines

 * Any complex, difficult protein

 * Efficient and effective glycosylation

PLATFORM


EVERYTHING YOU EXPECT FROM CELL LINE DEVELOPMENT
– YET WITHOUT THE PROBLEMS

Tailored Glycolysation
Flexible Genetic Engineering
Pathogen-Free Processing
Fusion Toxin Production

BUSINESS MODEL


AT ELEVA…

… we develop complex proteins into tomorrow’s drugs in partnership with
pharmaceutical companies

… we unlock the potential of difficult compounds that have so far failed to get
expressed

… we explore unusual opportunities in other promising fields

We have successfully developed enzymes and other proteins into clinical stages
and continue to scout for promising compounds. This results in a plethora of
opportunities. Whilst our technology platform remains the property of Eleva, new
individual assets will be developed in cooperation with pharmaceutical partners.
Each of such partnerships will be taken into a newly formed subsidiary. This
allows the partners to focus on the respective indication.


OUR PIPELINE


WE ARE INVITING PHARMACEUTICAL PARTNERS TO TAKE ALL CURRENT AND FUTURE
CANDIDATES TO CLINICAL SUCCESS.

INDICATION

RESEARCH

PRECLINICAL

PHASE I

PHASE II



THERAPIES FOR COMPLEMENT DISORDERS

C3 GLOMERULOPATHY (C3G)

Compleva FH/CPV-104 (natural complement regulator)


COMPLEMENT DISORDERS

Compleva MFHR1/CPV-102 (novel multi-level complement regulator)


COMPLEMENT DISORDERS

Compleva FHL/CPV-103 (natural complement regulator)



ENZYME REPLACEMENT THERAPIES

FABRY DISEASE

Repleva AGAL/RPV-001 (glyco-improved Fabry-ERT)


POMPE DISEASE

Repleva GAA/RPV-002 (glyco-improved Pompe-ERT)



RECENT NEWS

BJÖRN COCHLOVIUS NEW CEO OF ELEVA



Björn Cochlovius Ph.D. has become the new CEO of Eleva, a Freiburg-based biotech
company and the developer of “Bryotechnology”, a unique and pioneering process
for the moss-based production of complex therapeutic proteins. The renowned
oncologist, immunologist, and molecular biologist has nearly three decades of
experience in scientific, entrepreneurial, and advisory leadership roles in his
field.

Read More


ELEVA ENTERS CLINICAL DEVELOPMENT OF DIFFICULT-TO-EXPRESS HIGH-POTENTIAL
PROTEINS



Eleva, a manufacturer of superior biologics, is entering clinical phases with
its own drug candidates, such as immune-regulating factor H, as well as in
collaboration with pharmaceutical partners. Its moss-based platform is ideally
suited to produce difficult-to-express but therapeutically promising drug
candidates.

Read More


ELEVA REACHES INDUSTRIAL PRODUCTION SCALE AND PREPARES FOR CLINICAL DEVELOPMENT
OF FACTOR H



Eleva, a manufacturer of superior biologics, is scaling up its production
capacity to 2500 l in state-of-the-art single-use reactors. This will produce
sufficient quantities of factor H to cover all three clinical phases.

Read More




CONTACT

WE LOOK FORWARD TO HEARING FROM YOU!

eleva GmbH
Hans-Bunte-Str. 19
79108 Freiburg
Germany

Phone: +49 761 470 99 0
hello@elevabiologics.com


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Protection Regulation (DSGVO).

In accordance with Article 13 of the Basic Data Protection Regulation (DSGVO),
we would like to provide you with comprehensive information about the processing
of your personal data. You can read all relevant information in our data
protection policy.

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eleva GmbH

Hans-Bunte-Str. 19
79108 Freiburg, Germany

Phone: +49 761 470 99 0
hello@elevabiologics.com

Contact | Imprint | Privacy Policy

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