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OPEN REPOSITORY

Welcome to OPEN - the Repository of Open Scientific Publications, run by the
Interdisciplinary Centre for Mathematical and Computational Modelling,
University of Warsaw, previously operating as the CeON Repository. The
Repository enables Polish researchers from all fields to openly share their
articles, books, conference materials, reports, doctoral theses, and other
scientific texts.

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22382 ARCHIVED ITEMS


INSTITUTIONAL COMMUNITIES

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 * Instytut Badań Literackich PAN [186]
 * Instytut Chemii Fizycznej PAN [169]
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RECENT SUBMISSIONS

Item
Teatr, w którym dziecko jest twórcą. Obszary sprawczości dziecka w teatrze
(2022) Okurowska-Wabnic, Karolina; Akademia Sztuk Teatralnych im. Stanisława
Wyspiańskiego w Krakowie, Filia we Wrocławiu
Show more
Praca dotyczy problemu sprawczości dziecka w teatrze. Opisane zostały w niej
różne formy partycypacji dziecięcej oparte na partnerskiej relacji między
dziećmi i instruktorem / pedagogiem teatralnym. Socjologiczne i pedagogiczne
zmiany w postrzeganiu roli dziecka w kulturze zestawione są ze zmianami na
gruncie edukacji teatralnej. Na podstawie sylwetek i metod pracy wybranych
twórców i pedagogów teatralnych (Jan Dorman, Augusto Boal, Viola Spolin i Ketih
Johnstone) opracowane zostały zasady i warunki teatru opartego na sprawczości
dziecka, które koncentrują się na postawie instruktora, uwarunkowaniach
zewnętrznych oraz na równowadze między strukturyzacją a wolnością w procesie
teatralnym. Podsumowaniem pracy jest zaprezentowane konkretnych strategii i form
ćwiczeń w teatrze z ideą sprawczości. Przedstawiony zostaje proces powstawania
spektaklu od pierwszego spotkania z grupą, po trening aktorski, budowanie
fundamentów sprawczości, rozmowę i pracę nad scenariuszem.
Show more
Item
A Report on work: Cardiac MRI CBIR for pathologies detection
(SciTePress, 2023) Michno, Tomasz; Jelonek, Michał; Kielce University of
Technology; Center for Cardiovascular Research and Development, American Heart
of Poland
Show more
The early detection of pathologies in the cardiovascular system is very
important. One of the most accurate imaging examinations of human tissues is
magnetic resonance imaging (MRI), which is a very precise yet non-invasive test.
In order to process MRI images to detect pathologies, one of the most promising
methods is Content Based Image Retrieval (CBIR). This paper presents a report on
the research on that topic as a result of the Miniatura 5 Grant. The main
contributions of the paper are: a review of the state-of-the-art methods, a
selection of the most promising image features that may be used to identify
pathologies, a description of the proposed system for preparing suggestions for
doctors, which takes into consideration also methods for presenting the results,
which are most often omitted in other researches. The next step will be
incorporating full 3D MRI information into the pipeline.
Show more
Item
Microfluidic Formulationof Topological Hydrogels for Microtissue Engineering
(ACS Publications, 2022-09-15) Rojek, Katarzyna O.; Ćwiklińska, Monika; Kuczak,
Julia; Guzowski, Jan; Institute of Physical Chemistry, Polish Academy of
Sciences, Warsaw, Poland
Show more
Microfluidics has recently emerged as a powerful tool in generation of
submillimeter-sized cell aggregates capable of performing tissue-specific
functions, so-called microtissues, for applications in drug testing,
regenerative medicine, and cell therapies. In this work, we review the most
recent advances in the field, with particular focus on the formulation of
cell-encapsulating microgels of small “dimensionalities”: “0D” (particles), “1D”
(fibers), “2D” (sheets), etc., and with nontrivial internal topologies,
typically consisting of multiple compartments loaded with different types of
cells and/or biopolymers. Such structures, which we refer to as topological
hydrogels or topological microgels (examples including core–shell or Janus
microbeads and microfibers, hollow or porous microstructures, or granular
hydrogels) can be precisely tailored with high reproducibility and throughput by
using microfluidics and used to provide controlled “initial conditions” for cell
proliferation and maturation into functional tissue-like microstructures.
Microfluidic methods of formulation of topological biomaterials have enabled
significant progress in engineering of miniature tissues and organs, such as
pancreas, liver, muscle, bone, heart, neural tissue, or vasculature, as well as
in fabrication of tailored microenvironments for stem-cell expansion and
differentiation, or in cancer modeling, including generation of vascularized
tumors for personalized drug testing. We review the available microfluidic
fabrication methods by exploiting various cross-linking mechanisms and various
routes toward compartmentalization and critically discuss the available
tissue-specific applications. Finally, we list the remaining challenges such as
simplification of the microfluidic workflow for its widespread use in biomedical
research, bench-to-bedside transition including production upscaling, further in
vivo validation, generation of more precise organ-like models, as well as
incorporation of induced pluripotent stem cells as a step toward clinical
applications.
Show more
Item
Long-term day-by-day tracking of microvascular networks sprouting in fibrin
gels: From detailed morphological analyses to general growth rules
(AIP Publishing, 2024-02-06) Rojek, Katarzyna O.; Wrzos, Antoni; Żukowski,
Stanisław; Bogdan, Michał; Lisicki, Maciej; Szymczak, Piotr; Guzowski, Jan;
Institute of Physical Chemistry, Polish Academy of Sciences, Warsaw, Poland;
Institute of Theoretical Physics, Faculty of Physics, University of Warsaw,
Warsaw, Poland; Laboratoire Matière et Systèmes Complexes (MSC), UMR 7057, CNRS
& Université Paris Cité , Paris, France
Show more
Understanding and controlling of the evolution of sprouting vascular networks
remains one of the basic challenges in tissue engineering. Previous studies on
the vascularization dynamics have typically focused only on the phase of intense
growth and often lacked spatial control over the initial cell arrangement. Here,
we perform long-term day-by-day analysis of tens of isolated microvasculatures
sprouting from endothelial cell-coated spherical beads embedded in an external
fibrin gel. We systematically study the topological evolution of the sprouting
networks over their whole lifespan, i.e., for at least 14 days. We develop a
custom image analysis toolkit and quantify (i) the overall length and area of
the sprouts, (ii) the distributions of segment lengths and branching angles, and
(iii) the average number of branch generations—a measure of network complexity.
We show that higher concentrations of vascular endothelial growth factor (VEGF)
lead to earlier sprouting and more branched networks, yet without significantly
affecting the speed of growth of individual sprouts. We find that the mean
branching angle is weakly dependent on VEGF and typically in the range of
60°–75°, suggesting that, by comparison with the available diffusion-limited
growth models, the bifurcating tips tend to follow local VEGF gradients. At high
VEGF concentrations, we observe exponential distributions of segment lengths,
which signify purely stochastic branching. Our results—due to their high
statistical relevance—may serve as a benchmark for predictive models, while our
new image analysis toolkit, offering unique features and high speed of
operation, could be exploited in future angiogenic drug tests.
Show more
Item
Polonistyka światowa: archiwa i współczesność, tom 3: Glottodydaktyka i
językoznawstwo
(Stowarzyszenie Badaczy Popkultury i Edukacji Popkulturowej "Trickster",
2023-12-31) praca, zbiorowa; Dąbrowska, Anna; Jura, Marcin; Uniwersytet
Wrocławski
Show more
Trzeci tom zawierający materiały konferencyjne z VII Światowego Kongresu
Polonistów.
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1918 - 191911950 - 1979121980 - 20093.1K2010 - 202419.3K

AUTHOR

200 Klimczuk, Andrzej 142 Wojciechowska, Maja 117 Mazur, Piotr 101 Sobczak,
Elżbieta 99 Siuda, Piotr
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AFFILIATION

924 Uniwersytet Warszawski 658 Uniwersytet Jagielloński 636 Instytut Ekonomiki
Rolnictwa i Gospodarki Żywnościowej - Państwowy Instytut Badawczy 438
Uniwersytet Wrocławski 352 Katolicki Uniwersytet Lubelski Jana Pawła II
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SUBJECT

383 Polska 365 Poland 291 rodzina 285 edukacja 231 rolnictwo
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PUBLISHER

737 Instytut Ekonomiki Rolnictwa i Gospodarki Żywnościowej - Państwowy Instytut
Badawczy 448 Biuro Analiz Sejmowych 440 Towarzystwo Doktorantów UJ 327 Difin SA
176 Wydział Inżynierii Zarządzania Politechniki Białostockiej
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LICENSE

7.7K Dozwolony użytek 4.1K Uznanie autorstwa-Na tych samych warunkach 3.0 Polska
3.5K Uznanie autorstwa 3.0 Polska 2.8K Uznanie autorstwa-Użycie
niekomercyjne-Bez utworów zależnych 3.0 Polska 887 Uznanie autorstwa-Użycie
niekomercyjne-Na tych samych warunkach 3.0 Polska
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open.icm.edu.pl Open in urlscan Pro 213.135.60.139 Public Scan

Form analysis 9 forms found in the DOM

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open.icm.edu.pl Open in urlscan Pro
213.135.60.139 Public Scan

Form analysis
9 forms found in the DOM