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<h1>Adult Patients</h1>
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<p><strong>Surviving Sepsis Campaign 2021 Adult Guidelines</strong><br> The new "Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021" provides guidance for the clinician caring for adult patients
with sepsis or septic shock.</p>
<p><a data-feathr-click-track="true" href="https://doi.org/10.1097/CCM.0000000000005337" target="_blank"><em>Critical Care Medicine</em></a> |
<a data-feathr-click-track="true" href="https://link.springer.com/article/10.1007%2Fs00134-021-06506-y" target="_blank"><em>Intensive Care Medicine</em></a></p>
<h2 class="text-body">Related Resources</h2>
<div class="row">
<div class="col-md-3">
<a data-feathr-click-track="true" href="/sccm/media/PDFs/Surviving-Sepsis-Campaign-2021-Guidelines-Infographic_Anitbiotic-Timing.pdf?lang=en-US"><img alt="" src="/getmedia/220bdb8d-9ba0-49e7-8518-be31a284e5a9/Surviving-Sepsis-Campaign-2021-Guidelines-Infographic_Anitbiotic-Timing?width=250&height=250" style="width: 250px; height: 250px;"></a><br>
<strong>Antibiotic Timing Infographic</strong><br>
<a data-feathr-click-track="true" href="/sccm/media/PDFs/Surviving-Sepsis-Campaign-2021-Guidelines-Infographic_Anitbiotic-Timing.pdf?lang=en-US">Download</a>
</div>
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<a data-feathr-click-track="true" href="/sccm/media/PDFs/Surviving-Sepsis-Campaign-2021-Guidelines-Infographic_Vasoactive-Agent.pdf?lang=en-US"><img alt="" src="/getmedia/ae24301d-3089-411b-9469-6460534f682e/Surviving-Sepsis-Campaign-2021-Guidelines-Infographic_Vasoactive-Agent?width=250&height=250" style="width: 250px; height: 250px;"></a><br>
<strong>Vasoactive Agent Management Infographic</strong><br>
<a data-feathr-click-track="true" href="/sccm/media/PDFs/Surviving-Sepsis-Campaign-2021-Guidelines-Infographic_Vasoactive-Agent.pdf?lang=en-US">Download</a>
</div>
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<a data-feathr-click-track="true" href="http://journals.lww.com/10.1097/CCM.0000000000005357" target="_blank"><img alt="" src="/getmedia/0189a4f0-7835-4321-bb35-419b7bc34f3c/SSC-Executive-Summary?width=250&height=250" style="width: 250px; height: 250px;"></a>
<strong>Executive Summary</strong><br>
<a data-feathr-click-track="true" href="https://journals.lww.com/10.1097/CCM.0000000000005357" target="_blank">Read Now</a>
</div>
</div>
<p> </p>
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<ul>
<li><strong><a data-feathr-click-track="true" href="/sccm/media/PDFs/Surviving-Sepsis-Campaign-2021-Adult-Guidelines-Learning-Slides.pdf?lang=en-US" target="_blank">2021 Surviving Sepsis Guidelines Presentation</a></strong></li>
<li>Podcast:<strong>
<a data-feathr-click-track="true" href="https://www.esicm.org/esicm-talk-ssc-international-guidelines-management-sepsis-septic-shock-2021" target="_blank">SSC: International Guidelines for Management of Sepsis and Septic Shock 2021 - ESICM</a></strong>
</li>
<li><strong><a data-feathr-click-track="true" href="/Blog/October-2021/Surviving-Sepsis-Campaign-Releases-2021-Adult-Seps" target="_blank">Surviving Sepsis Campaign Releases 2021 Adult Sepsis Guidelines</a></strong></li>
<li><strong><a data-feathr-click-track="true" href="http://journals.lww.com/10.1097/CCM.0000000000005356" target="_blank">The Evolution of Toolkits and Bundles to Improve the Care of Sepsis Patients</a></strong></li>
</ul>
</div>
</div>
<p> </p>
<p><strong>Translations</strong><br>
<a data-feathr-click-track="true" href="/sccm/media/PDFs/Surviving-Sepsis-Campaign-2021-Portuguese-Translation.pdf" target="_blank">Portuguese Translation: Surviving Sepsis Campaign 2021 Guidelines</a>
</p>
<h2 class="text-body">SSC Adult Guidelines 2021: What's New and What's Changed?</h2>
<p><iframe allow="accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture" allowfullscreen="" frameborder="0" height="315" src="https://www.youtube.com/embed/rqgdvuzQ90E" title="YouTube video player"
width="560"></iframe></p>
<h3 class="text-body">Brief Guideline Updates</h3>
<p>Find brief guideline updates from heads of the guidelines writing groups. <a data-feathr-click-track="true" href="https://sccmvoices.gv-one.com/hive/ssc-guideline-summaries" target="_blank">View all updates.</a></p>
<p><a data-feathr-click-track="true" href="https://sccmvoices.gv-one.com/video.html?v=ux7qJph07NU=&token=5cd219d8aea95346d5f72d6e0404efdd" title="Watch Video">Infection Overview</a></p>
<p><a data-feathr-click-track="true" href="https://sccmvoices.gv-one.com/hive/ssc-guideline-summaries" target="_blank"><img alt="" src="https://sccmvoices.gv-one.com/video_thumbnail?v=ux7qJph07NU=&overlay=true" style="width: 400px;"></a>
</p>
<p> </p>
<p><a data-feathr-click-track="true" href="https://sccmvoices.gv-one.com/video.html?v=bkSwaCwuRz0=&token=83b510068e4c246906a7b365c9c95b1e" title="Watch Video">Screening & Early Treatment</a></p>
<p><a data-feathr-click-track="true" href="https://sccmvoices.gv-one.com/hive/ssc-guideline-summaries" target="_blank"><img alt="" src="https://sccmvoices.gv-one.com/video_thumbnail?v=bkSwaCwuRz0=&overlay=true" style="width: 400px;"></a>
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<p> </p>
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<a href="https://www.sccm.org/sccm/media/PDFs/Surviving-Sepsis-Campaign-Hour-1-Bundle.pdf" target="_blank"><img src="/sccm/media/ssc/BundleIcon-PinkBlue.png" alt=" Hour-1 Bundle Pocket Card & Infographic"></a>
<p><a href="https://www.sccm.org/sccm/media/PDFs/Surviving-Sepsis-Campaign-Hour-1-Bundle.pdf" target="_blank"> Hour-1 Bundle Pocket Card & Infographic</a></p>
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<p>The hour-1 bundle should be viewed as a quality improvement opportunity moving toward an ideal state. For critically ill patients with sepsis or septic shock, time is of the essence. Although the starting time for the Hour-1 bundle is
recognition of sepsis, both sepsis and septic shock should be viewed as <b>medical emergencies</b> requiring rapid diagnosis and immediate intervention. </p>
<p>The hour-1 bundle encourages clinicians to act as quickly as possible to obtain blood cultures, administer broad spectrum antibiotics, start appropriate fluid resuscitation, measure lactate, and begin vasopressors if clinically indicated.
Ideally these interventions would all begin in the first hour from sepsis recognition but may not necessarily be completed in the first hour. Minimizing the time to treatment acknowledges the urgency that exists for patients with sepsis and
septic shock. </p>
<p> <i>*</i><em>Note that the description of the hour-1 bundle above is the most current description, having passed all approval points effective October 10, 2019.</em><br>
<br>
<a href="/sccm/media/PDFs/Surviving-Sepsis-Campaign-Hour-1-Bundle.pdf" target="_blank">Hour-1 Bundle Pocket Card and Infographic </a>(see more resources below)<br>
<br>
<a href="https://www.sccm.org/sccm/media/PDFs/Surviving-Sepsis-Campaign-Bundle-Update-Process.pdf" target="_blank">How does the SSC update the bundle? </a>
</p>
<p><a href="https://sccmmedia.sccm.org/documents/Surviving-Sepsis-Campaign-Hour-1-Bundle-Teaching-Slides.pptx" target="_blank">Surviving Sepsis Campaign Hour-1 Bundle Teaching Slides</a></p>
<div><strong>SSC Hour-1 Bundle of Care Elements:</strong></div>
<ul>
<li>Measure lactate level*</li>
<li>Obtain blood cultures before administering antibiotics.</li>
<li>Administer broad-spectrum antibiotics.</li>
<li>Begin rapid administration of 30mL/kg crystalloid for hypotension or lactate level ≥ 4 mmol/L.</li>
<li>Apply vasopressors if hypotensive during or after fluid resuscitation to maintain MAP ≥ 65 mm Hg.</li>
</ul> * Remeasure lactate if initial lactate is elevated (> 2 mmol/L).
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* About SSC
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Adult Patients
ADULT PATIENTS
Surviving Sepsis Campaign 2021 Adult Guidelines
The new "Surviving Sepsis Campaign: International Guidelines for Management of
Sepsis and Septic Shock 2021" provides guidance for the clinician caring for
adult patients with sepsis or septic shock.
Critical Care Medicine | Intensive Care Medicine
RELATED RESOURCES
Antibiotic Timing Infographic
Download
Vasoactive Agent Management Infographic
Download
Executive Summary
Read Now
* 2021 Surviving Sepsis Guidelines Presentation
* Podcast: SSC: International Guidelines for Management of Sepsis and Septic
Shock 2021 - ESICM
* Surviving Sepsis Campaign Releases 2021 Adult Sepsis Guidelines
* The Evolution of Toolkits and Bundles to Improve the Care of Sepsis Patients
Translations
Portuguese Translation: Surviving Sepsis Campaign 2021 Guidelines
SSC ADULT GUIDELINES 2021: WHAT'S NEW AND WHAT'S CHANGED?
BRIEF GUIDELINE UPDATES
Find brief guideline updates from heads of the guidelines writing groups. View
all updates.
Infection Overview
Screening & Early Treatment
Hour-1 Bundle Pocket Card & Infographic
Guidance on the Guidelines and Bundle
Hour-1 Bundle Video
The hour-1 bundle should be viewed as a quality improvement opportunity moving
toward an ideal state. For critically ill patients with sepsis or septic shock,
time is of the essence. Although the starting time for the Hour-1 bundle is
recognition of sepsis, both sepsis and septic shock should be viewed as medical
emergencies requiring rapid diagnosis and immediate intervention.
The hour-1 bundle encourages clinicians to act as quickly as possible to obtain
blood cultures, administer broad spectrum antibiotics, start appropriate fluid
resuscitation, measure lactate, and begin vasopressors if clinically indicated.
Ideally these interventions would all begin in the first hour from sepsis
recognition but may not necessarily be completed in the first hour. Minimizing
the time to treatment acknowledges the urgency that exists for patients with
sepsis and septic shock.
*Note that the description of the hour-1 bundle above is the most current
description, having passed all approval points effective October 10, 2019.
Hour-1 Bundle Pocket Card and Infographic (see more resources below)
How does the SSC update the bundle?
Surviving Sepsis Campaign Hour-1 Bundle Teaching Slides
SSC Hour-1 Bundle of Care Elements:
* Measure lactate level*
* Obtain blood cultures before administering antibiotics.
* Administer broad-spectrum antibiotics.
* Begin rapid administration of 30mL/kg crystalloid for hypotension or lactate
level ≥ 4 mmol/L.
* Apply vasopressors if hypotensive during or after fluid resuscitation to
maintain MAP ≥ 65 mm Hg.
* Remeasure lactate if initial lactate is elevated (> 2 mmol/L).
The Surviving Sepsis Campaign (SSC) is a joint collaboration of the Society of
Critical Care Medicine (SCCM) and the European Society of Intensive Care
Medicine (ESICM) committed to reducing mortality and morbidity from sepsis and
septic shock worldwide. Read more
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The Society of Critical Care Medicine, SCCM and Critical Care Congress are
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