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EXPAREL® (BUPIVACAINE LIPOSOME INJECTABLE SUSPENSION) APPROVED FOR POSTSURGICAL
PAIN MANAGEMENT IN PEDIATRICS

Learn More


WE’RE DRIVING INNOVATION TO PROVIDE BETTER WAYS TO SAFELY AND EFFECTIVELY MANAGE
PAIN


ADVANCING PATIENT CARE

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ADVANCING PATIENT CARE

Overreliance on opioids in the postsurgical setting has set off a cascade of
negative consequences, ranging from potentially severe adverse events to the
risk of long-term use, misuse, and addiction.

Why we push for change


REDEFINING PAIN MANAGEMENT

 * EXPAREL® (bupivacaine liposome injectable suspension)
 * Proprietary multivesicular liposome (pMVL) technology
 * iovera°
 * ZILRETTA® (triamcinolone acetonide extended-release injectable suspension)


PROPRIETARY MULTIVESICULAR LIPOSOME (PMVL) TECHNOLOGY

Proprietary multivesicular liposome (pMVL) technology is an advanced drug
delivery platform that encapsulates drugs without altering their molecular
structure and then releases them over a desired period of time.

Learn More

Our long-acting local analgesic, EXPAREL® (bupivacaine liposome injectable
suspension), is a non-opioid medication administered at the time of surgery to
control pain while reducing opioid* requirements.

*The clinical benefit of the decrease in opioid consumption was not demonstrated
in the pivotal trials.

Learn More

Our iovera° system is an FDA-approved handheld cryoanalgesia device used to
deliver precise, controlled doses of cold temperature only to targeted nerves,
interrupting the nerve’s ability to transmit a pain signal. Results can be felt
immediately after iovera° treatment with pain relief that can last three months,
and in some cases longer, as the nerve regenerates over time.

The iovera° system offers a non-opioid solution for the management of pain
associated with both orthopedic surgery and persistent orthopedic conditions
such as osteoarthritis.

Learn More

ZILRETTA® (triamcinolone acetonide extended-release injectable suspension) is
the first and only approved treatment for osteoarthritis (OA) knee pain
utilizing extended-release microsphere technology.

ZILRETTA is a non-opioid option for significant extended relief of OA knee pain.

Learn More



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EXPAREL® (bupivacaine liposome injectable suspension), ioverao, ZILRETTA®
(triamcinolone acetonide extended-release injectable suspension), and Pacira are
registered trademarks of the respective subsidiaries of Pacira BioSciences, Inc.
All other trademarks referenced herein are the property of their respective
owners.

©2024 Pacira Pharmaceuticals, Inc., a wholly owned subsidiary of Pacira
BioSciences, Inc.