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Cite article Article metrics: 231 views



CITE THIS ARTICLE



Vilares Ana Teresa, Ciabattoni Riccardo, Cunha Teresa Margarida, Félix Ana
(2022) Cervical cancer in Cape Verde: reappraisal upon referral to a tertiary
cancer centre ecancer 16 1471

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https://doi.org/10.3332/ecancer.2022.1471
Abstract | Full Article | PDF


RESEARCH


CERVICAL CANCER IN CAPE VERDE: REAPPRAISAL UPON REFERRAL TO A TERTIARY CANCER
CENTRE

17 Nov 2022
Ana Teresa Vilares, Riccardo Ciabattoni, Teresa Margarida Cunha, Ana Félix

Background: Cervical cancer (CC) is the first cause of cancer-related deaths
among Cape Verdean women. The absence of a national screening programme and a
lack of dedicated cancer treatment facilities contribute to its high mortality
rate. In an effort to improve the prognosis of these women, a health cooperation
agreement was established between Portugal and Cape Verde (CV), allowing their
evacuation to Portuguese hospitals. Our aim was to characterise CC among CV
women, and to assess the response given to these patients in Instituto Português
de Oncologia de Lisboa Francisco Gentil (IPOLFG), so that their treatment and
follow-up protocols can be optimised and overall prognosis improved.

Methods: Retrospective evaluation of women diagnosed with CC in CV that
underwent therapy in IPOLFG between 2013 and 2020. Risk factors, demographic and
tumour characteristics, treatment and outcomes were reviewed.

Results: Fifty-eight patients were included. Squamous cell carcinoma was the
most frequent (91.5%) histological type. HPV DNA was present in 25 out of 26
samples.The agreement rate between the pathology analysis performed in CV and in
Portugal was high (87.9%); however, the agreement regarding the FIGO stage was
low (15.5%). This may be explained by both the time interval between diagnosis
and treatment (around 6 months) and by the absence of resources to accurately
stage the disease in CV. In IPOLFG, 77.6% of patients received combined
chemo-radiotherapy. Post-treatment follow-up varied widely, due to
disease-related and bureaucratic issues. Eighteen patients developed
cancer-related complications and/or cancer-related death. The survival rate and
median overall survival (OS) in our cohort were of 89.7% and 73.2 months,
respectively.

Conclusions: Although most women had advanced-stage disease, the OS in our
cohort was better than what has been reported for other African countries,
probably because state-of-the-art treatment, frequently not accessible in those
countries, was offered to all patients.

Article metrics: 231 views
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