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Home — Global Center for Health Security — The Transmission — What Is Disease X?
How Scientists Are Preparing for the Next Pandemic


WHAT IS DISEASE X? HOW SCIENTISTS ARE PREPARING FOR THE NEXT PANDEMIC

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 * Published Sep 27, 2023

Washington Post It sounds like something Elon Musk might have cooked up:
“Disease X.” In fact, the term was coined years ago as a way of getting
scientists to work on medical countermeasures for unknown infectious threats —
novel coronaviruses like the one that causes Covid-19, for example — instead of
just known ones, like the Ebola virus. The idea was to encourage the development
of platform technologies, including vaccines, drug therapies and diagnostic
tests, that could be rapidly adapted and deployed in response to an array of
future outbreaks with epidemic or pandemic potential. 

1. What is ‘Disease X?’

It’s the somewhat mysterious name for an illness caused by a presently unknown,
yet serious microbial threat. The World Health Organization added Disease X in
2017 to a short list of pathogens deemed a top priority for research, alongside
known killers like Severe Acute Respiratory Syndrome (SARS) and Ebola. Covid-19,
caused by a novel coronavirus, was an example of a Disease X when it touched off
the pandemic at the end of 2019. The vast reservoir of viruses circulating in
wildlife are seen as a likely source of more such diseases. That’s because of
their potential to spill over and infect other species, including humans, giving
rise to an infection against which people will have no immunity.

2. What’s the point of studying Disease X?

As the WHO puts it, it’s to “enable early cross-cutting R&D preparedness that is
also relevant” for an unknown disease. The humanitarian crisis sparked by the
2014–2016 Ebola epidemic in West Africa was a wake up call. Despite decades of
research, there were no products ready to deploy in time to save more than
11,000 lives. In response, the WHO created an R&D Blueprint to accelerate
development of a range of tools for “priority diseases.” The current list
includes:

• Covid-19,

• Crimean-Congo hemorrhagic fever,

• Ebola virus disease and Marburg virus disease,

• Lassa fever,

• Middle East respiratory syndrome (MERS) and SARS,

• Nipah and henipaviral diseases,

• Rift Valley fever,

• Zika,

Continue Reading




1 COMMENT

 1. Onyayi William WHO says:
    November 23, 2023 at 5:45 am
    
    Thank you for the update
    
    Reply
    


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