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 * Lab Partnering

 * (773) 665-4005


WHICH CANCER DRUG IS RIGHT FOR YOU?





Cancer drugs have an average of 75% chance they WILL NOT work for you.

That means that 75% of the time that you take a chemo drug for 6 months it will
literally have NO EFFECT on stopping your cancer.  In spite of having to
experience awful side effects you would get NO EFFECT on stopping the cancer. 

 

80% of the time a cancer drug doesn’t work, it is because of your specific
genetic mutations.

Humans know very little about gene mutations. We only know what 1% of our gene
mutations actually do. So generally, we had no idea if your specific mutations
were going to cause a drug not to work.

 

UNTIL NOW . . . Read on to find out why 

Or watch this webinar now




DO YOU HAVE HER2+ CANCER?
OR DID YOUR DOCTOR ORDER (OR WANT TO ORDER) A BIOPSY TO SEE IF YOU HAVE HER2+
CANCER?



HER2 is actually the name of one of the genes in your body found on the long arm
of chromosome 17 (17q12).

When the HER2 gene has a mutation, it often causes the body (and specifically
the breasts) to make more HER2 protein.  The abundance of that protein is what
stimulates cancer growth in the breast tissue. 

When they do a biopsy of the tumor, they measure how much HER2 protein is in the
tissue.  They give the protein a value from 0 to 4. Anything about 2 is
considered to be HER2+ cancer (they assume since there is a lot of HER2 protein,
that is what is causing your cancer).

A value of 2+ means you may have HER2+ cancer – It’s a doctors call.

A value of 0 and 1  means your cancer is not HER2+

When they do the biopsy they usually check for estrogen and progesterone to see
if you are Estrogen or Progesterone positive.

If you don’t have any of these 3 things the cancer is called “triple negative”
(HER2 protein, estrogen and progesterone are all negative).  Doctors often call
this the worst breast cancer, because the treatment options are severely limited
with western medicine. Triple negative has the worst survival rate of all the
types of breast cancer.


IF YOU ARE HER2+ YOUR DOCTOR PROBABLY HAS OR WILL PRESCRIBE ONE OF THESE 3 MEDS.


LAPATINIB


NERATITNIB


TUCATINIB




THIS WEBSITE WILL PROVIDE YOU WITH MORE INFORMATION ABOUT THESE DRUGS AND HER2+
CANCER.





WATCH THIS WEBINAR VIDEO. IT IS ALL ABOUT HER2+ CANCER, AND THE DRUGS COMMONLY
USED TO TREAT HER2+ CANCER.




Finally learn which of the 3 most common meds for HER2+ cancer 


YOU ARE SENSITIVE OR RESISTANT TO.




WHAT DOES “SENSITIVE” OR “RESISTANT” MEAN?

Sensitive means the drug will bind to it's target spot.
Resistant means – the drug will not bind to it's target spot.



HOW DOES THAT HELP YOU?


WHAT DOES THAT MEAN?

Well, it is generally accepted that if a drug cannot bind to your cells, it will
NOT WORK for you. Hence if you are RESISTANT to a drug, it won’t work for you
because it WILL NOT bind to it’s target spot. Therefore, don’t give it and don’t
take it.

80% of the time (Link) if you are resistant, its because of your genetic
mutations.

That means, because of the way one of your genes is mutated (the HER2 Gene in
this case)it changes the 3 dimensional shape of the gene. This change in shape
causes the drug to no longer fit into the “binding pocket”.

Imagine it like this, if you have a lock and key that fit perfectly, and were
designed to go together, then the lock is changed, that same key will NO LONGER
FIT.

That is exactly what is happening, Your genes are the “lock” that has changed
shape because of a mutation. That mutation stops the “Key” or drug, from fitting
into the place it was designed to work.

Some mutations are already known to cause drug resistance. For example, there
are 3 mutations, that cause resistance to Lapatinib.  And your doctor can
already check for these mutations, and know in advance if lapatinib will NOT
work. (But they still don’t know if it will work).

The problem is, there are over 6,000 possible mutations in the area that
Lapatinib binds, that POSSIBLY could cause the drug not to work.  Of those
6,000, no one knew how 5,400 of those possible mutations would keep the drug
from binding……UNTIL NOW




UNTIL NOW.

 * We at TruGene have mapped out EVERY mutation in the region of the HER2 Gene
   that the 3 most common drugs prescribed bind to.
 * We have mapped them out with these 3 drugs present. So we know EVERY
   mutations effect on the binding of these 3 drugs and whether it will allow
   the drug to bind or not. Thus showing whether you are sensitive to the drug
   or not.
 * Up until now NO ONE can tell if you are sensitive to a drug, because they
   don’t know what 99% of any given mutation does in the body, let alone what it
   does to the bindability of the drug to it's target site.
 * Not only do we know the 3 of the mutations that will cause resistance to
   lapatinib that everyone else knows; but we know all 256 mutations that will
   cause resistance to Lapatinib. We at Trugene, also know 267 mutations for
   Tucatanib and 289 for Neratinib. Which is ALL of them.

FIND OUT HOW WE KNOW THIS, WHEN NO ONE ELSE IN THE WORLD DOES!

AND WHY SO MANY CANCER MEDS WON’T WORK FOR SPECIFIC PEOPLE.


WATCH THE VIDEO NOW.

Find out if we can help you and your doctor by telling you which meds you are
sensitive or resistant to.




It is really that easy

Normally this test is $997

For a limited time, we are offering it at 50% off the next 100 people pay only
$497.

Order today before the test price goes up.

(Most insurance will pay for or give a discount for the Tempus Test.

(CURRENT RESULTS PROCESSING IS 2-3 MONTHS)




 * +1 (773) 665-4005
 * dr@trugenediagnostics.com
 * 3839 McKinney Ave. #251 Dallas, TX 75204

PRODUCTS

Clinical Diagnostics

Companion Diagnostics

Genetic Testing For Cancer

Improving Genetic Diagnostics

Whole Gene Biomarkers

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