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VHP4Safety: Towards safety assessment based on human data  
About VHP4Safety
VHP4Safety News & Events
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MEET THE CREW - ANIEK DE WINTER

Spotlight
11 days ago
Get to know your VHP4Safety colleagues better in our monthly Meet the Crew! Hi
Aniek! Can you tell us a little bit about yourself? My name is Aniek de Winter
and I am 27 years old. I have a bachelor in Biotechnology, during which I became
very interested in why people do or do not accept certain technological
innovations, such as GMOs. That’s why I decided to do a second masters in
Communication and Innovation, next to my masters in Biotechnology. After
graduating my masters, I worked at a consultancy firm for 8 months, until a
friend told me that the VHP4Safety project was looking for somebody with a
background in both biology and science communication. This was like music to my
ears, so I applied for the job and that’s why I’m here now! And what will you be
doing for VHP4Safety? I am responsible for the communication and stakeholder
engagement, so what Sara and Bas did before, but it is now combined in one job.
The communication part means updating the website, making LinkedIn posts,
sending the Newsflash et cetera. The stakeholder engagement part means that I’m
part of Research Line 3, focusing in the societal part of the Virtual Human
Platform. What is needed to make sure that the platform will be accepted by
regulators and in society as a possible replacement for animal testing? I’m
looking into ways for stakeholders to contribute to these goals. What interests
you the most about the VHP4Safety project? What interests me most is the
interdisciplinarity and the challenges that come along with this. As a social
scientist, it makes me very enthusiastic that there is a whole research line in
this project that is focused specifically on ensuring societal acceptance. But
still it can be challenging to get the researchers out of their own bubbles and
to work in an interdisciplinary way. I think the Common Language Taskforce plays
a very nice role in this and I think the glossary that they created is very
helpful for fostering the interdisciplinary collaboration. I also think that
events like the Designathons and Hackathons are very useful for this. And then a
word about yourself, what do you do when you're not busy with your research? In
my free time, I play trumpet in a cover band named the Great Cover-Up. I have
played trumpet since I was nine years old and I still enjoy it a lot! Making
music together with others really energizes me. Also, I recently found a new
hobby, gardening! This year I am growing my own vegetables for the first time. I
hope that the weather will soon get better so the slugs will stop eating all of
my plants!



RECAP OF THE 5TH DESIGNATHON

Spotlight
2 months ago
Report of the 5th VHP4Safety Designathon On Monday, 13 May, the 5th VHP4Safety
Designathon took place, offering engaging and informative sessions. The day
began with an introduction by Anne Kienhuis, followed by an update from Ozan on
the state of the platform. The Taskforce Risk Assessment then hosted a session
on managing uncertainties in risk assessment, introduced by Jacqueline van
Engelen. Participants were divided into three groups to discuss specific
subtopics: exposure, QIVIVE, and (q)AOPs. Each group presented their findings in
a plenary session before breaking for lunch. In the afternoon, Isaac Ortega
Alvarado presented on the perspective of end users, distinguishing between
stakeholders and users. This was followed by a discussion on identifying the end
users of the Virtual Human Platform. Participants then worked in breakout groups
to explore the needs of specific end user categories. After a short coffee
break, these groups shared their insights. The final session featured Marc
Teunis, who gave a presentation on the use of AI in risk assessment, sparking
discussions on the advantages and disadvantages of AI. The event concluded with
closing remarks from Anne Kienhuis, followed by a networking session with
drinks.

VHP4Safety Social Feed
LinkedIn VHP

18 days ago
The past two days many of our colleagues were present at the 45th annual meeting
of the @Nederlandse Vereniging voor Toxicologie (NVT). It was a very interesting
event with insightful presentations, interactive sessions, and inspiring
discussions. It was also a treat to explore other exciting projects on NAMs. A
special congratulations to @Nathalie Dierichs on winning the PhD Platform
presentation prize and to @Elise van der Koogh on winning the Master student
poster prize! #NLTox #Toxicology #NAMs



LinkedIn VHP

2 months ago
Last Monday, we successfully held the 5th VHP4Safety Designathon! This edition
focused on tackling challenges in risk assessment and understanding the
perspective of the end user—both essential for the platform's ongoing
development. Stay tuned for more updates as we continue to advance our work! 💡
Read the report of the day here: https://lnkd.in/eWnwHft6. #VHP4Safety
#Innovation #RiskAssessment #UserExperience



LinkedIn VHP

2 months ago
Last Friday, the VHP4Safety-ONTOX Collaboration Day took place, followed by the
VHP4Safety Symposium! During the morning there were a lot of interesting
discussions on several topics on which VHP4Safety and @ONTOX will strengthen
their collaboration. In the afternoon, the VHP4Safety Symposium provided a
platform for all PhD candidates of VHP4Safety to present their research to the
academic partners involved in the project. A very fruitful day filled with
valuable insights and networking opportunities. We are looking forward to what
we can achieve together! https://lnkd.in/e8fgP4Xr



LinkedIn VHP

3 months ago
Last Thursday, Young @Transitie Proefdiervrije Innovatie presented their
manifesto! One of the key strategies that they identified was Transition
Science, on which our colleague @Jarno Hoekman gave a very interesting
presentation at this event. The audience gained valuable insights into the
dynamics of socio-technical transitions. Let's harness this knowledge to drive
the transition to animal-free research! Read the Young TPI manifesto here:
https://lnkd.in/en5KHJ_b.



LinkedIn VHP

4 months ago
This week our colleagues @Ivo Djidrovski, PhD and @Marc Teunis are present at
the EPAA Designathon in Ispra, Italy, themed “Innovations in New Approach
Methodologies”. They are representing the #PKMine team, constituted in
collaboration with @ONTOX. Wishing all participants the best for a productive
and inspiring event!



read_more


VHP4SAFETY-ONTOX COLLABORATION DAY AND VHP4SAFETY SYMPOSIUM RECAP

Spotlight
2 months ago
On Friday 26 April, the VHP4Safety-ONTOX Collaboration Day took place, followed
by the VHP4Safety Symposium in the afternoon. The Collaboration Day started with
insightful presentations by Anne Kienhuis (VHP4Safety) and Mathieu Vinken
(ONTOX), who outlined the overarching goals of both projects and the governance
structure that will underpin the collaboration between the two projects. Our
partnership is structured around six "Collaboration Groups" (CGs) focusing on
the following topics: qAOPs, Chemical Selection, Risk Assessment, Data
Management, Stakeholder Involvement, and IT Platforms. Following the
presentations by Anne and Mathieu, leaders of each CG pitched ideas for
collaboration, setting the stage for the breakout groups. These groups engaged
in interesting discussions on ways to enhance our joint efforts. The morning
session concluded with a presentation of the outcomes from these discussions,
leading into a well-deserved lunch break. The afternoon was dedicated to the
VHP4Safety Symposium, where PhD candidates had the opportunity to present their
research to the academic partners of the project. Each presentation was followed
by a productive exchange of ideas from researchers from various work packages,
providing new perspectives to the PhD candidates. The day concluded with a nice
and interactive closing activity from our coordinator Juliette Legler, followed
by networking drinks. All in all, it was a very fruitful day filled with
valuable insights and networking opportunities. We are enthusiastic about the
future and the achievements that our continued collaboration will bring!



MEET THE CREW - ISAAC ORTEGA ALVARADO

Spotlight
3 months ago
Interview with Isaac Ortega Alvarado, postdoc researcher in VHP4Safety Hi Isaac!
Could you tell us a little bit about yourself? Hi! My name is Isaac Ortega
Alvarado. I am from Costa Rica, where I did my bachelors. I have a bachelors in
communication and industrial design engineering. After these, I started working
mainly on commercial projects. Then, I took a master’s degree in design in
Turkey, a different life experience. I also worked on my master’s research in
Portugal. After completing my master’s, I went for a PhD at the Norwegian
University of Science and Technology, in Trondheim, Norway. So, I have been
moving around quite a bit for the last ten years! And what do you do in the
project? In VHP4Safety, I work as a postdoc researcher in work package 3.1 since
15 February. I am currently trying to bring a user perspective to the project.
This perspective has been requested in the project by the people building the
platform, as they are interested in knowing who they are building it for. I’m
coming with this perspective, and the project has been going on for almost three
years, so a lot of information and knowledge has already been collected. I’m
interested in seeing how this information can converge into something that could
become the Virtual Human Platform. How has it been for you to move to the
Netherlands? I had been to the Netherlands before, so in general, it was not
very surprising. But I have been a bit surprised about the weather. It has been
very rainy since I got here. The temperatures are higher than I expected; it’s a
lot warmer than in Norway, where I lived during the past five years. In January,
when I came here, I was expecting to see more snow, haha. Why is the project of
interest to you personally? Personally, I see this project as responsible
innovation. The research in the project can be beneficial for everybody. In the
end, the whole society can benefit from it, not just one group. When is
VHP4Safety a success for you? For me, success will be when the tools or
infrastructure for risk assessment change. I think the goal should be better
risk assessment, not necessarily creating a virtual human or avoiding the use of
animals. These are also successes, but to my understanding, the aim of the
project is to enable better risk assessment. What has struck you recently while
working on the project? Everything! I’m a designer, I don’t have a biology or
chemistry-related background, like most people in the project. A lot of the
things that I’m learning are entirely new to me. I also have a social science
background, which makes working on a transdisciplinary project like this very
interesting. And then a word about yourself, what do you do when you're not busy
with your research? I like going for long walks, like really long walks. The
longest I have ever walked is 62 kilometers in one day. So do you have any plans
to join the “Nijmeegse Vierdaagse” some time, the four-day walking event in the
East of the Netherlands? That sounds good, I will definitely check it out!