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Plus, the next episode of our comic strip, Sequenced






TAKING ANIMAL MODELS OUT OF PRECLINICAL TESTING WITH MICROPHYSICAL SYSTEMS

What do spheroids, organoids, and organs on chips have in common? These are all
examples of microphysical systems — 3D cell cultures that aim to mimic the
environment in the body. As these models have improved over the years, they’ve
garnered increasing attention as potential replacements for in vivo testing of
new drugs, offering faster time-to-results and decreased reliance on animal
testing. But in order for these models to work, high-throughput methods are
needed to assess the effects of the drug. Read a case study supporting the use
of Bio-Plex Assays in concert with a kidney-on-chip system for rapid assessment
of kidney toxicity.

Early Disease Detection with AI: New on BioRad.io

Early detection of cancer and other diseases can significantly improve patient
prognosis. Tune into this episode for the lowdown on development of noninvasive
early screening tools, from biomarker identification to clinical performance.

Next Up on Sequenced, Our Next-Gen Sequencing Comic

In the second episode of Sequenced, Terence learns the basics of RNA-Seq from a
postdoc, but things get off to a rough start. Is he already ready for
extraction? Check out our comic strip to find out.

Chromatography Lab Sets Students Up for Success

Dr. Dominique Ingato is a faculty member at MiraCosta College with a passion for
mentoring the next generation of scientists. Read about how her teaching lab
gives students real, hands-on experience with state-of-the-art instrumentation.

How to Build Bigger Immunophenotyping Panels

As flow cytometers have become more advanced, so have multicolor
immunophenotyping assays. But with this complexity comes new challenges. Find
out how StarBright Dyes can alleviate common issues and enable reliable results.

Excellence in RNA Therapeutics

RNA therapeutics have greatly expanded the range of potential targets for new
drugs, but their development requires exceptional precision. Droplet Digital PCR
has what it takes, but don’t take our word for it — read real examples where it
has transformed processes.

Bridging the Sequencing Gap with SEQuoia Kits

Though RNA-Seq is now a common technique, limitations with cost and sample
compatibility still prevent its use in some cases. See how SEQuoia Library Prep
Kits and new short-read sequencers can bring RNA-Seq to more labs.

Assess Viral Clearance in Early-Phase Process Development

See how a design of experiments (DOE) approach was used to study the effect of
buffer pH and conductivity on the removal of product and process impurities by
an AEX mixed-mode resin, CHT media, and a high-resolution CEX resin.



 

Featured Webinars

DOE — mAb Process Development Using Mixed-Mode Resins

This webinar presents a two-step monoclonal antibody purification workflow and
compares multimodal resin alternatives for polishing. See how both mixed-mode
resin studies and their DOE approaches can achieve high-purity products.

A Culture-Free Method for SARS-CoV-2 NT50 Determination

Measuring 50% neutralization titer (NT50) can be a time-consuming process that’s
challenging to scale. Learn how a Bio-Plex Neutralization Antibody Assay can be
used for rapid SARS-CoV-2 NT50 determination in current and future variants.



 

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