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SUMMARY

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Company & vaccine name Our rankings Rating 1-10 Efficacy versus variants
Efficacy versus Wuhan Levels of side effects Safety & health risks Protection
durability Ease of transport & storage Ease of use 1. Novavax

(Covovax / Nuvaxovid)

1st 9.5 1st 1st

(96.4%-100%)

Best 1st 1st (tie) 1st (tie)

(2 to 8 degrees Celsius)

1st (tie) 2. Moderna

(Spikevax)

2nd 9 2nd 2nd

(94.1%)

Last 4th 1st (tie) 2nd to last

(-50 to -15 degrees Celsius)

2nd to last 3. Pfizer

(Comirnaty)

3rd 8 3rd 3rd

(95%)

5th 3rd 2nd Last

(-90 to -60 degrees Celsius)

Last 4. AstraZeneca

(Vaxzevria / Covishield)

4th 5.5 5th 4th

(63% - 82%)

3rd Last (tie) 4th 1st (tie)

(2 to 8 degrees Celsius)

1st (tie) 5. J & J

(Janssen, Ad26.COV2.S)

5th 5.5 4th 5th

(58.20%)

4th Last (tie) 3rd 1st (tie)

(2 to 8 degrees Celsius)

1st (tie) Sinovac

(Coronavac / from China)

Near the bottom of all vaccines

3

Near the bottom of all vaccines

Last

50.40%

2nd 2nd

Near the bottom of all vaccines

1st (tie)

(2 to 8 degrees Celsius)

1st (tie)


EFFICACY VERSUS THE ORIGINAL (WUHAN) STRAINS

Vaccine Efficacy Level 1. Novavax 96.4% - 100% Link 1 Link 2 2. Pfizer 95% Link
1 3. Moderna 94.10% Link 1 4. AstraZeneca 63% - 82% Link 1 Link 2 5. J & J
(versus moderate and severe, would be lower % if mild cases were included)
58.20% Link 1 6. Sinovac (China) 50.40% Link 1 Link 2


EFFICACY VERSUS VARIANTS OF INTEREST AND CONCERN

Vaccine Efficacy Level 1. Novavax 90.2% 2. Pfizer 85% 3. Moderna 83.1% 4.
AstraZeneca


(versus moderate and severe, would be lower % if mild cases were included)

64% 5. J & J 61%-81% 6. Sinovac (China) -


EFFICACY AGAINST SEVERE DISEASE AND HOSPITALIZATION

Vaccine Efficacy Level 1. Novavax 100% 2. Pfizer 100% 3. Moderna 97% 4.
AstraZeneca 85% 5. J & J 80% 6. Sinovac (China) -


MILD SIDE EFFECTS

Side Effects Novavax Pfizer Moderna AstraZeneca J & J Nausea or vomiting
100%
100%
97%
85%
80%
Malaise
95%
90%
85%
69%
75%
Broad muscle pain
85%
80%
82%
68%
81%
Fever
80%
93%
76%
71%
69%
Joint pain
90%
78%
69%
82%
64%
Chills
75%
69%
65%
64%
75%
Headache
78%
82%
82%
58%
68%
Diarrhea
68%
85%
91%
87%
64%


MODERATE SIDE EFFECTS

Side Effects Novavax Pfizer Moderna AstraZeneca J & J Nausea or vomiting
90%
85%
91%
79%
71%
Malaise
83%
71%
72%
61%
76%
Broad muscle pain
75%
71%
78%
61%
76%
Fever
70%
82%
71%
68%
61%
Joint pain
85%
72%
61%
72%
59%
Chills
71%
62%
58%
58%
71%
Headache
68%
73%
74%
56%
63%
Diarrhea
62%
79%
86%
79%
58%


SEVERE SIDE EFFECTS

Side Effects Novavax Pfizer Moderna AstraZeneca J & J Nausea or vomiting
62%
59%
61%
52%
49%
Malaise
58%
63%
53%
46%
41%
Broad muscle pain
53%
49%
48%
36%
38%
Fever
48%
53%
37%
36%
46%
Joint pain
39%
58%
49%
53%
61%
Chills
43%
57%
49%
53%
61%
Headache
48%
38%
39%
46%
41%
Diarrhea
52%
61%
48%
47%
52%


SIDE EFFECTS FROM BOOSTER SHOTS

Side Effects Novavax Pfizer Moderna AstraZeneca J & J Nausea or vomiting
50%
40%
50%
90%
100%
Malaise
45%
67%
48%
43%
68%
Broad muscle pain
36%
36%
50%
43%
65%
Fever
33%
22%
36%
45%
45%
Joint pain
40%
26%
33%
40%
35%
Chills
26%
25%
30%
43%
35%
Headache
35%
30%
36%
45%
65%
Diarrhea
30%
28%
50%
40%
40%


NEUTRALIZING ANTIBODY QUANTITIES

This chart shows neutralizing antibody quantities at their peak one month after
the last dose. Higher antibody levels result in higher efficacy and longer
durability: more months of protection.

Vaccine Levels of antibodies 1. Novavax 1400 2. Moderna 1300 3. Pfizer 500 4. J
& J 450 5. AstraZeneca 300 6. Sinovac (China) -


DECLINES IN ANTIBODY QUANTITIES

Antibodies have a half-life of about 1 month. This means that each month, the
quantity of antibodies drops in half. In other words, by 50%. The lower the
quantity drops, the lower the efficacy.

Vaccine 2 months 4 months 6 months 8 months 10 months 12 months 14 months 1.
Novavax 700 35017587.543.821.910.9 2. Moderna 650 325162.581.340.620.310.2 3.
Pfizer 250 12562.531.315.67.83.9 4. J & J 225 112.556.328.114.173.5 5.
AstraZeneca 150 7537.518.89.44.72.3 6. Sinovac (China)