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We're Hiring! icon / arrow linked in instagram twitter Fill 1 * 01 HOME * 02 ABOUT NGM PARTNERSHIP OPPORTUNITIES * 03 DISCOVERY ENGINE ONCOLOGY RETINAL DISEASE LIVER & METABOLIC DISEASE PUBLICATIONS * 04 PIPELINE * 05 TEAM * 06 INVESTORS & MEDIA * 07 CAREERS * 08 CONTACT EXPLORERS ON THE FRONTIER OF LIFE-CHANGING SCIENCE. At NGM, we are charting new paths and pushing beyond boundaries to discover and deliver medicines for people whose health and lives have been disrupted by disease. icon / arrow SCROLL TO DISCOVER JUNE 30, 2022 32 Questions at NGM Bio with President, Siobhan Nolan Mangini and CEO, David Woodhouse icon / arrow diagonal Our mission is to translate complex, powerful biology with rigor and urgency into life-changing medicines. Our vision is to make lasting scientific contributions that improve human life. icon / arrow Learn More LATEST NGM BIO NEWS 9/13/2022 - PRESS RELEASE NGM BIO PRESENTS UPDATED PRELIMINARY FINDINGS FROM THE ONGOING PH... icon / arrow Read More 9/6/2022 - PRESS RELEASE NGM BIO PRESENTS UPDATED PRELIMINARY FINDINGS FOR A SUBGROUP OF P... icon / arrow Read More 8/15/2022 - PRESS RELEASE NGM BIO ANNOUNCES PRESENTATIONS FEATURING UPDATED FINDINGS FROM T... icon / arrow Read More OUR PIPELINE WE ARE ADVANCING OUR BROAD AND DIVERSE PIPELINE OF BIOLOGIC DRUG CANDIDATES, ALL DISCOVERED IN-HOUSE, WITH THE GOAL OF ADDRESSING LARGE UNMET MEDICAL NEEDS IN CANCER AND OTHER DISEASES THAT IMPACT THE LIVES OF MILLIONS AROUND THE WORLD. View Full Pipeline icon / → ONCOLOGY MYELOID REPROGRAMMING AND CHECKPOINT INHIBITION PORTFOLIO NGM707 NGM707 DUAL ILT2/ILT4 ANTAGONIST ANTIBODY Advanced Solid Tumors Phase 1/2 Trial (Enrolling) Monotherapy and Combination Therapy with KEYTRUDA® (pembrolizumab) Advanced Solid Tumors Phase 1/2 Trial (Enrolling) Monotherapy and Combination Therapy with KEYTRUDA® (pembrolizumab) NGM831 NGM831 ILT3 ANTAGONIST ANTIBODY Advanced Solid Tumors Phase 1a/1b Trial (Enrolling) Monotherapy and Combination Therapy with KEYTRUDA Advanced Solid Tumors Phase 1a/1b Trial (Enrolling) Monotherapy and Combination Therapy with KEYTRUDA NGM438 NGM438 LAIR1 ANTAGONIST ANTIBODY Advanced Solid Tumors Phase 1a/1b Trial (Enrolling) Monotherapy and Combination Therapy with KEYTRUDA Advanced Solid Tumors Phase 1a/1b Trial (Enrolling) Monotherapy and Combination Therapy with KEYTRUDA CANCER & CACHEXIA NGM120 NGM120 GFRAL ANTAGONIST ANTIBODY Advanced Solid Tumors Phase 2 PINNACLES Trial (Enrolling Patients with Metastatic Pancreatic Cancer) Phase 1a/1b Trial (Ongoing) Advanced Solid Tumors Phase 2 PINNACLES Trial (Enrolling Patients with Metastatic Pancreatic Cancer) Phase 1a/1b Trial (Ongoing) RETINAL DISEASES NGM621 NGM621 ANTI-COMPLEMENT C3 ANTIBODY Geographic Atrophy Phase 2 CATALINA Trial (Enrollment completed) Merck Right to Option at Proof-of-Concept Geographic Atrophy Phase 2 CATALINA Trial (Enrollment completed) Merck Right to Option at Proof-of-Concept LIVER & METABOLIC DISEASES MK-3655 MK-3655 FGFR1C/KLB AGONISTIC ANTIBODY NASH F2/F3 Phase 2b Trial (Enrolling) Merck Optioned at Proof-of-Concept NASH F2/F3 Phase 2b Trial (Enrolling) Merck Optioned at Proof-of-Concept Aldafermin Aldafermin FGF19 ANALOG NASH F4 Phase 2b ALPINE 4 Trial (Enrollment completed) NASH F4 Phase 2b ALPINE 4 Trial (Enrollment completed) NGM'S DISCOVERY ENGINE * Approach BIOLOGY-LED INNOVATION NGM is built on a straightforward central premise: create an environment that allows drug discovery research to thrive by focusing on powerful human biology unconstrained by therapeutic area or technology approach. Regardless of where it leads us, our scientific exploration is grounded in a singular motivation: deliver important medicines to address critical unmet medical needs in grievous diseases. The heart and soul of NGM, our discovery engine fuels ongoing innovation and is the source of our diverse and growing pipeline of candidates. icon / arrow Learn More * Expertise * Output * Scientific Values BIOLOGY-LED INNOVATION NGM is built on a straightforward central premise: create an environment that allows drug discovery research to thrive by focusing on powerful human biology unconstrained by therapeutic area or technology approach. Regardless of where it leads us, our scientific exploration is grounded in a singular motivation: deliver important medicines to address critical unmet medical needs in grievous diseases. The heart and soul of NGM, our discovery engine fuels ongoing innovation and is the source of our diverse and growing pipeline of candidates. icon / arrow Learn More BIOLOGICAL AND PROTEIN ENGINEERING EXPERTISE We integrate deep expertise in experimental biology with leading capabilities in protein and antibody engineering. This approach drives a synergy that allows us to rapidly test multiple hypotheses, identify compelling targets and use the resulting biological insights to engineer promising drug candidates. icon / arrow Learn More BROAD AND DIVERSE PORTFOLIO Our discovery engine has yielded a deep portfolio of drug candidates, currently spanning oncology, retinal diseases and liver and metabolic diseases. Beyond our disclosed programs, we have multiple research programs — all generated from our discovery engine — vying to deliver our next clinical candidate. icon / arrow Learn More PRINCIPLES AND PURPOSE At NGM, science comes first. We pride ourselves on the daily pursuit of excellence and a culture of scientific rigor that extends from our drug discovery efforts through clinical development. Our scientific values ground and guide us as we work together to explore complex biology and advance new medicines for patients in need. icon / arrow Learn More MEET OUR TEAM We are explorers — 200+ strong. We are awed by human biology, undaunted by difficult problems, committed to excellence, optimistic about what lies ahead and humbled by the privilege and responsibility of discovering and developing medicines for our fellow humans. icon / arrow Meet Our Team CAREERS AT NGM We are seeking fellow explorers with a pioneering spirit, a penchant to break free from convention, an eagerness to contribute in meaningful ways, and an innate desire to make a difference in the world through the advancement of life-changing medicines. Join Us icon / → BUILT FROM SCRATCH. LED BY BIOLOGY. MOTIVATED BY PATIENTS. icon / arrow Learn More Group 3 Explorers on the frontier of life-changing science. * Careers * Contact * Terms of Use * Privacy Policy twitter instagram linked in © 2022 NGM Biopharmaceuticals. All Rights Reserved. PRIVACY PREFERENCE CENTER When you visit any website, it may store or retrieve information on your browser, mostly in the form of cookies. This information might be about you, your preferences or your device and is mostly used to make the site work as you expect it to. The information does not usually directly identify you, but it can give you a more personalized web experience. Because we respect your right to privacy, you can choose not to allow some types of cookies. Click on the different category headings to find out more and change our default settings. However, blocking some types of cookies may impact your experience of the site and the services we are able to offer. More information Allow All MANAGE CONSENT PREFERENCES STRICTLY NECESSARY COOKIES Always Active These cookies are necessary for the website to function and cannot be switched off in our systems. They are usually only set in response to actions made by you which amount to a request for services, such as setting your privacy preferences, logging in or filling in forms. You can set your browser to block or alert you about these cookies, but some parts of the site will not then work. These cookies do not store any personally identifiable information. PERFORMANCE COOKIES Performance Cookies These cookies allow us to count visits and traffic sources so we can measure and improve the performance of our site. They help us to know which pages are the most and least popular and see how visitors move around the site. All information these cookies collect is aggregated and therefore anonymous. If you do not allow these cookies we will not know when you have visited our site, and will not be able to monitor its performance. TARGETING COOKIES Targeting Cookies These cookies may be set through our site by our advertising partners. They may be used by those companies to build a profile of your interests and show you relevant adverts on other sites. They do not store directly personal information, but are based on uniquely identifying your browser and internet device. If you do not allow these cookies, you will experience less targeted advertising. Back Button PERFORMANCE COOKIES Vendor Search Search Icon Filter Icon Clear checkbox label label Apply Cancel Consent Leg.Interest checkbox label label checkbox label label checkbox label label Reject All Confirm My Choices By clicking “Accept All Cookies”, you agree to the storing of cookies on your device to enhance site navigation, assist in marketing efforts, and analyze site usage.Read about cookies in our Privacy Policy. 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