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Prescribing Info Including Patient Info
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Prescribing Info Including Patient Info
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Prescribing Info Including Patient Info

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Important Safety Information:
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Important Safety Information:

What is the most important information I should know about ADAKVEO?

ADAKVEO may cause serious side effects, including infusion-related
reactions. Infusion-related reactions. Infusion-related react... See More

 

Approved Use:

What is ADAKVEO® (crizanlizumab-tmca)?

ADAKVEO is a prescription medicine used in people 16 years of age and older who
have sickle cell disease to help reduce how often painful crises happen.

It is not known if ADAKVEO is safe and effective in children under 16 years of
age.... See More Read full Important Safety Information and Approved Use

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I AM AN ADULT LIVING WITH SICKLE CELL DISEASE AND HAVE BEEN PRESCRIBED ADAKVEO

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I AM THE LEGAL GUARDIAN OF A 16 OR 17 YEAR OLD PRESCRIBED ADAKVEO

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Approved Use

What is ADAKVEO® (crizanlizumab-tmca)?

ADAKVEO is a prescription medicine used in people 16 years of age and older who
have sickle cell disease to help reduce how often painful crises happen.

It is not known if ADAKVEO is safe and effective in children under 16 years of
age.

Important Safety Information

What is the most important information I should know about ADAKVEO?

ADAKVEO may cause serious side effects, including infusion-related reactions.

Infusion-related reactions. Infusion-related reactions may happen during or
within 24 hours of receiving an infusion of ADAKVEO. Your health care provider
may slow down, temporarily stop, or completely stop your infusion with ADAKVEO
if you have an infusion-related reaction. You may continue to receive ADAKVEO at
a slower infusion rate, and your health care provider may give you certain
medicines before your infusion to lower your risk of getting an infusion-related
reaction. Your health care provider should monitor you for signs and symptoms of
infusion-related reactions and treat your symptoms as needed. Tell your health
care provider right away if you get any of the following signs and symptoms of
an infusion-related reaction:

 * pain in various locations
 * headache
 * fever
 * chills or shivering
 * nausea
 * vomiting
 * diarrhea

 * tiredness
 * dizziness
 * sweating
 * hives
 * itching
 * shortness of breath or wheezing

 * pain in various locations
 * headache
 * fever
 * chills or shivering
 * nausea
 * vomiting
 * diarrhea
 * tiredness
 * dizziness
 * sweating
 * hives
 * itching
 * shortness of breath or wheezing

 

ADAKVEO may interfere with a blood test.

Tell your health care provider that you are receiving ADAKVEO before having any
blood tests. ADAKVEO may interfere with a laboratory test to measure your
platelet counts.

Before receiving ADAKVEO, tell your health care provider about all of your
medical conditions, including if you

 * are pregnant or plan to become pregnant. ADAKVEO may harm your unborn baby
 * are breastfeeding or plan to breastfeed. It is not known if ADAKVEO passes
   into your breast milk. You and your health care provider should decide the
   best way to feed your baby during treatment with ADAKVEO

Tell your health care provider about all of the medicines you take, including
prescription and over-the-counter medicines, vitamins, and herbal supplements.

The most common side effects of ADAKVEO include:

 * nausea
 * joint pain
 * back pain

 * stomach-area (abdominal) pain or tenderness
 * fever

 * nausea
 * joint pain
 * back pain
 * stomach-area (abdominal) pain or tenderness
 * fever

 

These are not all of the possible side effects of ADAKVEO. For more information,
ask your health care provider or pharmacist.

Call your doctor for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the
FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Please see full Prescribing Information, including Patient Information.

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