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This activity has been developed under the direction of Alcon.

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ALCON ROUNDTABLE

As modern cataract surgery has evolved into a refractive procedure, advancements
in IOL technologies now offer surgeons many design options to reduce spectacle
dependency and achieve different lifestyle and vision goals.1-4 With the variety
of IOL options available today, it becomes imperative for surgeons to use
standardized methods to assess and compare the visual quality and refractive
performance of these IOLs for better informed IOL selection to meet patients’
needs with expected outcomes.2-4 The lack of a defined standard to categorize
monofocal IOLs with enhanced intermediate vision can lead to mislabeling these
lenses as extended depth of focus (EDOF) IOLs and contribute to IOL category
confusion, inaccurate expectations of IOL performance and unsatisfactory
outcomes.5 The American National Standards Institute defines the criteria for
classifying EDOF IOLs5; furthermore, defocus curve testing can assess and
compare the range of vision provided by different presbyopia-mitigating IOLs.3,6
The Clareon® Vivity® EDOF IOL (Alcon) is the first and only non-diffractive EDOF
IOL designed with wavefront-shaping technology to increase depth of focus,
demonstrating a monofocal-like distance, excellent intermediate, and functional
near vision without significant visual disturbances.1 Recent study findings
compared the clinical outcomes of the Clareon® monofocal IOL (Alcon) with the
Eyhance™ monofocal IOL (Johnson & Johnson Vision) and found no significant
difference between these IOLs for best corrected distance visual acuity,
distance corrected intermediate visual acuity, target corrected intermediate
visual acuity or defocus curve testing. The study data help elucidate the
similar range of vision that may be expected from the Clareon® and Eyhance™
monofocal IOLs.7

In this roundtable discussion, a panel of experts discuss the history of
monofocal IOLs and the evolution of IOL designs as they review the process
behind Alcon’s innovative advancements in IOL technology. The experts share
their experiences with the Vivity® EDOF IOL and patient selection preferences
for improved outcomes.1 Learn more about the importance of data-driven
technology for the progress of cataract surgery outcomes and fulfillment of
patient needs.

This roundtable discussion is sponsored by Alcon.


MODERATOR



Stephen S. Lane, MD
Chief Medical Officer
Alcon






FACULTY



Rob Scott, PhD
Vice President, Intraocular Devices R&D
Alcon







J. Morgan Micheletti, MD, FACS*
Cataract/Refractive/Anterior Segment Surgeon
Director of Research at Berkeley Eye Center







Cathleen M. McCabe, MD*
Medical Director and Cataract/Refractive Surgeon
Eye Associates of Manatee





*Faculty members are paid consultants of Alcon.


VIDEO


HISTORY OF MONOFOCAL IOLS





WATCH


VIDEO


EARLY GENERATION ATIOLS





WATCH


VIDEO


DEFOCUS CURVES EVALUATE TRUE RANGE OF VISION





WATCH


VIDEO


IDEATION AND DEVELOPMENT OF THE FIRST AND ONLY NON-DIFFRACTIVE PCIOL, VIVITY®





WATCH


VIDEO


CLARIFYING THE IOL CATEGORY CONFUSION





WATCH


VIDEO


CLARIFY THE CATEGORY: MONOFOCAL “PLUS” VS. EXTENDED DEPTH OF FOCUS IOLS





WATCH


VIDEO


EXPERT PANEL DISCUSSION ON TARGETING MINI-MONOVISION





WATCH


VIDEO


EXTENDING THE RANGE OF VISION WITH VIVITY AND PANOPTIX





WATCH


VIDEO


ALCON’S COMMITMENT TO INNOVATION





WATCH


REFERENCES

 1. Bala C, Poyales F, Guarro M, et al. Multicountry clinical outcomes of a new
    nondiffractive presbyopia-correcting IOL. J Cataract Refract Surg.
    2022;48(2):136-143. doi:10.1097/j.jcrs.0000000000000712
 2. McCabe C, Berdahl J, Reiser H, et al. Clinical outcomes in a U.S.
    registration study of a new EDOF intraocular lens with a nondiffractive
    design. J Cataract Refract Surg. 2022;48(11):1297-1304.
    doi:10.1097/j.jcrs.0000000000000978
 3. Böhm M, Petermann K, Hemkeppler E, Kohnen T. Defocus curves of 4
    presbyopia-correcting IOL designs: diffractive panfocal, diffractive
    trifocal, segmental refractive, and extended-depth-of-focus. J Cataract
    Refract Surg. 2019;45(11):1625-1636. doi:10.1016/j.jcrs.2019.07.014
 4. Kanclerz P, Toto F, Grzybowski A, Alio JL. Extended depth-of-field
    intraocular lenses: an update. Asia Pac J Ophthalmol (Phila).
    2020;9(3):194-202. doi:10.1097/APO.0000000000000296
 5. Fernández J, Rocha-de-Lossada C, Zamorano-Martín F, Rodríguez-Calvo-de-Mora
    M, Rodríguez-Vallejo M. Positioning of enhanced monofocal intraocular lenses
    between conventional monofocal and extended depth of focus lenses: a scoping
    review. BMC Ophthalmol. 2023;23(1):101. doi:10.1186/s12886-023-02844-1
 6. Kohnen T, Lemp-Hull J, Suryakumar R. Defocus curves: focusing on factors
    influencing assessment. J Cataract Refract Surg. 2022;48(8):961-968.
    doi:10.1097/j.jcrs.0000000000000906
 7. Micheletti JM, Duncan N, Hall B. Head-to-head comparison of intermediate
    vision of two monofocal intraocular lenses. Presented at: American Society
    of Cataract and Refractive Surgery (ASCRS) Annual Meeting; May 6, 2023. San
    Diego, CA.




LEARN MORE ABOUT ALCON

Learn More
© 2023 Alcon Inc. 08/23 US-VIV-2300020


Important Product Information – Clareon® Aspheric Family of Hydrophobic Acrylic
IOLs

CAUTION: Federal law restricts this device to sale by or on the order of a
physician.

INDICATION: The Clareon® Aspheric Hydrophobic Acrylic IOLs include the Clareon®
Aspheric and Clareon® Aspheric Toric IOLs and are indicated for primary
implantation in the capsular bag in the posterior chamber of the eye for the
visual correction of aphakia in adult patients in whom a cataractous lens has
been removed. In addition, the Clareon® Aspheric Toric IOL is indicated to
correct pre-existing corneal astigmatism.

WARNINGS/PRECAUTIONS:
The Clareon® IOL is intended for implantation in the capsular bag only.
Physicians considering lens implantation under any of the following
circumstances should weigh the potential risk/benefit ratio: Patients in whom
the posterior capsule is ruptured, zonules are damaged, or primary posterior
capsulotomy is planned.

Careful preoperative evaluation and sound clinical judgment should be used by
the surgeon to decide the risk/benefit ratio before implanting the IOL in a
patient with any of the conditions described in the Directions for Use.

For the Clareon® Aspheric Toric IOLs, rotation can reduce astigmatic correction;
if necessary lens repositioning should occur as early as possible prior to lens
encapsulation.

As with any surgical procedure, there is risk involved. Potential complications
accompanying cataract and/or IOL implantation surgery may include, but are not
limited to, the following: lens epithelial cell on- growth, corneal endothelial
cell damage, infection (endophthalmitis), toxic anterior segment syndrome
(TASS), retinal detachment, vitritis, cystoid macular edema, corneal edema,
pupillary block, cyclitic membrane, iris prolapse, hypopyon, anterior uveitis,
hyphema, pigment dispersion, posterior capsule opacification, transient or
persistent glaucoma, and secondary surgical interventions. Secondary surgical
interventions include, but are not limited to: lens repositioning, lens
replacement, vitreous aspiration or iridectomy for pupillary block, wound leak
repair, and retinal detachment repair.

Prior to surgery, prospective patients should be informed of the possible risks
and benefits associated with this IOL as well as the risks and benefits
associated with cataract surgery. After surgery, physicians should provide an
implant card to patients regarding the IOL implanted.

DO NOT re-sterilize the Clareon® IOL by any method. The device is for single use
only.

ATTENTION: Refer to the Directions for Use labeling for a complete list of
indications, warnings and precautions.

Important Safety Information

Important Product Information – Clareon® Aspheric Family of Hydrophobic Acrylic
IOLs

CAUTION: Federal law restricts this device to sale by or on the order of a
physician.

INDICATION: The Clareon® Aspheric Hydrophobic Acrylic IOLs include the Clareon®
Aspheric and Clareon® Aspheric Toric IOLs and are indicated for primary
implantation in the capsular bag in the posterior chamber of the eye for the
visual correction of aphakia in adult patients in whom a cataractous lens has
been removed. In addition, the Clareon® Aspheric Toric IOL is indicated to
correct pre-existing corneal astigmatism.

WARNINGS/PRECAUTIONS:
The Clareon® IOL is intended for implantation in the capsular bag only.
Physicians considering lens implantation under any of the following
circumstances should weigh the potential risk/benefit ratio: Patients in whom
the posterior capsule is ruptured, zonules are damaged, or primary posterior
capsulotomy is planned.

Careful preoperative evaluation and sound clinical judgment should be used by
the surgeon to decide the risk/benefit ratio before implanting the IOL in a
patient with any of the conditions described in the Directions for Use.

For the Clareon® Aspheric Toric IOLs, rotation can reduce astigmatic correction;
if necessary lens repositioning should occur as early as possible prior to lens
encapsulation.

As with any surgical procedure, there is risk involved. Potential complications
accompanying cataract and/or IOL implantation surgery may include, but are not
limited to, the following: lens epithelial cell on- growth, corneal endothelial
cell damage, infection (endophthalmitis), toxic anterior segment syndrome
(TASS), retinal detachment, vitritis, cystoid macular edema, corneal edema,
pupillary block, cyclitic membrane, iris prolapse, hypopyon, anterior uveitis,
hyphema, pigment dispersion, posterior capsule opacification, transient or
persistent glaucoma, and secondary surgical interventions. Secondary surgical
interventions include, but are not limited to: lens repositioning, lens
replacement, vitreous aspiration or iridectomy for pupillary block, wound leak
repair, and retinal detachment repair.

Prior to surgery, prospective patients should be informed of the possible risks
and benefits associated with this IOL as well as the risks and benefits
associated with cataract surgery. After surgery, physicians should provide an
implant card to patients regarding the IOL implanted.

DO NOT re-sterilize the Clareon® IOL by any method. The device is for single use
only.

ATTENTION: Refer to the Directions for Use labeling for a complete list of
indications, warnings and precautions.

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