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Skip to main content Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript. 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Four scientists discuss the generation of a human pangenome, and what insights can be gained from it. * Arya Massarat * Melissa Gymrek * Hákon Jónsson News & Views Forum 10 May 2023 * A CLUE TO THE CATALYTIC ACTIVATION OF SPLICING The processing of messenger RNA during splicing requires the activity of a complex of RNAs and proteins termed the spliceosome. Structural data shed light on previously mysterious aspects of splicing in humans. * Soo-Chen Cheng News & Views 10 May 2023 * VACCINE BOOSTS T CELLS THAT TARGET PANCREATIC TUMOURS Efforts to tackle pancreatic cancer by harnessing immune cells have had limited success. A clinical trial reports promising results from testing a personalized approach to boosting immune responses to such tumours. * Amanda L. 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Taylor News & Views 03 May 2023 Nature is a Transformative Journal; authors can publish using the traditional publishing route OR via immediate gold Open Access. Our Open Access option complies with funder and institutional requirements. LATEST RESEARCH ARTICLES * RESOLVED IMAGING CONFIRMS A RADIATION BELT AROUND AN ULTRACOOL DWARF * Melodie M. Kao * Amy J. Mioduszewski * Evgenya L. Shkolnik Article 15 May 2023 * SPECTROSCOPIC IDENTIFICATION OF WATER EMISSION FROM A MAIN-BELT COMET * Michael S. P. Kelley * Henry H. Hsieh * Heidi B. Hammel Article 15 May 2023 * ABSENCE OF NEAR-AMBIENT SUPERCONDUCTIVITY IN LUH2±XNY * Xue Ming * Ying-Jie Zhang * Hai-Hu Wen Article 11 May 2023 * NON-ABELIAN BRAIDING OF GRAPH VERTICES IN A SUPERCONDUCTING PROCESSOR A unitary protocol for braiding projective non-Abelian Ising anyons in a generalized stabilizer code is implemented on a superconducting processor, allowing for verification of their fusion rules and realization of their exchange statistics. * T. I. Andersen * Y. D. Lensky * P. Roushan Article Open Access 11 May 2023 * A REFLECTIVE, METAL-RICH ATMOSPHERE FOR GJ 1214B FROM ITS JWST PHASE CURVE * Eliza M.-R. Kempton * Michael Zhang * Peter McGill Article 10 May 2023 COLLECTIONS CHRONIC KIDNEY DISEASE Every 30 minutes, our kidneys filter all the blood in the body. Nature Outlook 08 Mar 2023 Advertisement TRENDING - ALTMETRIC * A DRAFT HUMAN PANGENOME REFERENCE * PERSONALIZED RNA NEOANTIGEN VACCINES STIMULATE T CELLS IN PANCREATIC CANCER * TIMING MATTERS FOR COVID VACCINE EFFECTIVENESS * DE NOVO EVOLUTION OF MACROSCOPIC MULTICELLULARITY JOBS * PRINCIPAL SCIENTIST - ORAL BIOLOGICS About the Department ... Lexington, Massachusetts Novo Nordisk * W2 PROFESSORSHIP FOR OPHTHALMOLOGY (M/F/D) At the University Medical Center Greifswald, a legal entity of the University of Greifswald, a W2 professorship for ophthalmology (m/f/d) in the Cl... 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